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The map label for this gene is rssA [H]

Identifier: 116690637

GI number: 116690637

Start: 2898893

End: 2900239

Strand: Reverse

Name: rssA [H]

Synonym: Bcen2424_2617

Alternate gene names: 116690637

Gene position: 2900239-2898893 (Counterclockwise)

Preceding gene: 116690638

Following gene: 116690636

Centisome position: 83.25

GC content: 72.61

Gene sequence:

>1347_bases
GTGCGGTCGATTCGTCATCAATTGCTGATCTGGCTGCTCGCGATCGTCGTCGCGGGCGTGGGCATGGCGGGCTGGCTCAT
CTACCGGCAGGCGCTCGCGGAAGCGAACGAGCTGTTCGACTACCAGTTGCAGGAAATCGCCGCGGCGCTGCCGTCCGAAC
CGTTCTCGCAGGTGTTCGGCTCGCGCACCAACGGCGACGAAGGCATCGTGATCCAGATCTGGAACCGCAACGGCGTGCTG
ATGTACTTCTCGCATCCGCGCGCGCCGATCGCGCCGCGCGCGGAGCTCGGCTTCTCGACTGAGCGCACCGATCGCGGCGA
ATGGCGCGTGTACGGGGCGATCGTCGGCGACAACGTCGTGCAGCTCGCGCAGCCGCTGTCGGTGCGCAACCGGCTGGCGG
CGAACGTCGCGCTGCGCACGCTGTGGCCGCTGATCGTGCTGCTGCCGTTCCTCGGCGCGGCCGTGTGGGGAATCGTCGGG
CGCGGGCTCGCGCCGCTCGGCCGCGTGACGCGCGCGGTCGAGGCGCGCCGGCCGGAAGCGCTCGATTCGCTGCCCGACGC
GCGCCTGCCGCTCGAGGTGCAGCCGCTCGTGCGGGCGCTGAACGGGCTGCTCGCGCGGCTGGCGGCGGCGCTCGACACGC
AGAAGGCGTTCGTCGCCGATGCCGCGCACGAGTTGCGCACGCCGCTCGCGGCCGTGCAGATCCAGGCGCAGCTCGTCGCC
CGCGCGAAGGACGACGCATCGCGCCGCGAGGCGATCGCGGATCTCCAGGACGGCGTGTCGCGCGCGACGCGTCTCACCGA
GCAACTGCTCGCGCTCGCGCGCGCCGAACCGGACGGCGCGACGATGCGCGAACCGGTCGACCTGCAGGCGCTGCTCGCCG
AATGCGTGGCCGCGCATGCGCCGCTCGCGCAGCGGCACGACATCGATCTCGGCTTCGAGGAAACCCGCGCGGCGAGCGTC
GTCGCGGACGTCGGCGCGCTGCGCGTGATGTTCGGCAACCTGCTCGACAACGCGGTGAAGTACACGCCGGACGGCGGCCG
CATCGACGTGTCGCTGACGCGCGACGCGGCTGGCCGCGCGTGCGTGCAGATCGCCGACAGCGGGCCGGGCATTCCGGCCG
ACGAGCGCGAGCGCGTGTTCGACCGCTTCTATCGCGACAGCTCGGCGCGGGCACGCACCGACGTGTCGGGCAGCGGGCTC
GGGCTCGCGATCGTCAAGCGCGTGGCGGCGCAGCAGGGCGCGACGGTGTCGCTCGGCGATGCAGCCGCGGGCGGCCTGCT
CGTCAGCGTCGTGTTCCGCGATGCCGAGATGCCGGCCCCGGCCCCGCAGCCTTCCGAATCTGCCTGA

Upstream 100 bases:

>100_bases
GGTCGAGGTCTACATCCACGCGCTGCGCAAGAAGCTCGGCTCGGACCTGATCCGCAACGTGCGCGGGCTCGGCTACATGG
TCGTCAAGGAAAGCTGACGC

Downstream 100 bases:

>100_bases
AGGGCGGTGTGCCGGCCGGATGCCGGCAGCCGCTTAAGCCCCGCTTAAGGCTGATTAAGCCTCCTTTAAGTCAGGGTCGT
TACGCTGCGTCCTAACAACG

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MRSIRHQLLIWLLAIVVAGVGMAGWLIYRQALAEANELFDYQLQEIAAALPSEPFSQVFGSRTNGDEGIVIQIWNRNGVL
MYFSHPRAPIAPRAELGFSTERTDRGEWRVYGAIVGDNVVQLAQPLSVRNRLAANVALRTLWPLIVLLPFLGAAVWGIVG
RGLAPLGRVTRAVEARRPEALDSLPDARLPLEVQPLVRALNGLLARLAAALDTQKAFVADAAHELRTPLAAVQIQAQLVA
RAKDDASRREAIADLQDGVSRATRLTEQLLALARAEPDGATMREPVDLQALLAECVAAHAPLAQRHDIDLGFEETRAASV
VADVGALRVMFGNLLDNAVKYTPDGGRIDVSLTRDAAGRACVQIADSGPGIPADERERVFDRFYRDSSARARTDVSGSGL
GLAIVKRVAAQQGATVSLGDAAAGGLLVSVVFRDAEMPAPAPQPSESA

Sequences:

>Translated_448_residues
MRSIRHQLLIWLLAIVVAGVGMAGWLIYRQALAEANELFDYQLQEIAAALPSEPFSQVFGSRTNGDEGIVIQIWNRNGVL
MYFSHPRAPIAPRAELGFSTERTDRGEWRVYGAIVGDNVVQLAQPLSVRNRLAANVALRTLWPLIVLLPFLGAAVWGIVG
RGLAPLGRVTRAVEARRPEALDSLPDARLPLEVQPLVRALNGLLARLAAALDTQKAFVADAAHELRTPLAAVQIQAQLVA
RAKDDASRREAIADLQDGVSRATRLTEQLLALARAEPDGATMREPVDLQALLAECVAAHAPLAQRHDIDLGFEETRAASV
VADVGALRVMFGNLLDNAVKYTPDGGRIDVSLTRDAAGRACVQIADSGPGIPADERERVFDRFYRDSSARARTDVSGSGL
GLAIVKRVAAQQGATVSLGDAAAGGLLVSVVFRDAEMPAPAPQPSESA
>Mature_448_residues
MRSIRHQLLIWLLAIVVAGVGMAGWLIYRQALAEANELFDYQLQEIAAALPSEPFSQVFGSRTNGDEGIVIQIWNRNGVL
MYFSHPRAPIAPRAELGFSTERTDRGEWRVYGAIVGDNVVQLAQPLSVRNRLAANVALRTLWPLIVLLPFLGAAVWGIVG
RGLAPLGRVTRAVEARRPEALDSLPDARLPLEVQPLVRALNGLLARLAAALDTQKAFVADAAHELRTPLAAVQIQAQLVA
RAKDDASRREAIADLQDGVSRATRLTEQLLALARAEPDGATMREPVDLQALLAECVAAHAPLAQRHDIDLGFEETRAASV
VADVGALRVMFGNLLDNAVKYTPDGGRIDVSLTRDAAGRACVQIADSGPGIPADERERVFDRFYRDSSARARTDVSGSGL
GLAIVKRVAAQQGATVSLGDAAAGGLLVSVVFRDAEMPAPAPQPSESA

Specific function: Member of the two-component regulatory system rssA/rssB involved in regulation of swarming motility which has been shown to be inhibited by saturated fatty acids. RssA/rssB regulates cellular fatty acid composition, hemolysin production and cell surface t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=457, Percent_Identity=29.7592997811816, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1786783, Length=275, Percent_Identity=28.7272727272727, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788393, Length=244, Percent_Identity=31.9672131147541, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1788279, Length=317, Percent_Identity=27.1293375394322, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1790551, Length=273, Percent_Identity=31.1355311355311, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786600, Length=220, Percent_Identity=31.8181818181818, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1787374, Length=292, Percent_Identity=27.7397260273973, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790861, Length=299, Percent_Identity=31.1036789297659, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1789808, Length=252, Percent_Identity=29.3650793650794, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790346, Length=229, Percent_Identity=27.9475982532751, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI48994928, Length=244, Percent_Identity=23.7704918032787, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI87082128, Length=257, Percent_Identity=28.4046692607004, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787894, Length=239, Percent_Identity=28.8702928870293, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1789149, Length=212, Percent_Identity=25.9433962264151, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786912, Length=239, Percent_Identity=27.6150627615063, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788713, Length=267, Percent_Identity=26.5917602996255, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788549, Length=212, Percent_Identity=26.8867924528302, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI145693157, Length=220, Percent_Identity=25.4545454545455, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790436, Length=209, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 47985; Mature: 47985

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSIRHQLLIWLLAIVVAGVGMAGWLIYRQALAEANELFDYQLQEIAAALPSEPFSQVFG
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCC
SRTNGDEGIVIQIWNRNGVLMYFSHPRAPIAPRAELGFSTERTDRGEWRVYGAIVGDNVV
CCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCHHCCCCCCCCCCCCEEEEEEECCCHHH
QLAQPLSVRNRLAANVALRTLWPLIVLLPFLGAAVWGIVGRGLAPLGRVTRAVEARRPEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHH
LDSLPDARLPLEVQPLVRALNGLLARLAAALDTQKAFVADAAHELRTPLAAVQIQAQLVA
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
RAKDDASRREAIADLQDGVSRATRLTEQLLALARAEPDGATMREPVDLQALLAECVAAHA
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHC
PLAQRHDIDLGFEETRAASVVADVGALRVMFGNLLDNAVKYTPDGGRIDVSLTRDAAGRA
CCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCCCE
CVQIADSGPGIPADERERVFDRFYRDSSARARTDVSGSGLGLAIVKRVAAQQGATVSLGD
EEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCC
AAAGGLLVSVVFRDAEMPAPAPQPSESA
HHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MRSIRHQLLIWLLAIVVAGVGMAGWLIYRQALAEANELFDYQLQEIAAALPSEPFSQVFG
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCC
SRTNGDEGIVIQIWNRNGVLMYFSHPRAPIAPRAELGFSTERTDRGEWRVYGAIVGDNVV
CCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCHHCCCCCCCCCCCCEEEEEEECCCHHH
QLAQPLSVRNRLAANVALRTLWPLIVLLPFLGAAVWGIVGRGLAPLGRVTRAVEARRPEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHH
LDSLPDARLPLEVQPLVRALNGLLARLAAALDTQKAFVADAAHELRTPLAAVQIQAQLVA
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
RAKDDASRREAIADLQDGVSRATRLTEQLLALARAEPDGATMREPVDLQALLAECVAAHA
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHC
PLAQRHDIDLGFEETRAASVVADVGALRVMFGNLLDNAVKYTPDGGRIDVSLTRDAAGRA
CCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCCCE
CVQIADSGPGIPADERERVFDRFYRDSSARARTDVSGSGLGLAIVKRVAAQQGATVSLGD
EEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCC
AAAGGLLVSVVFRDAEMPAPAPQPSESA
HHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA