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The map label for this gene is kynB [H]

Identifier: 116690597

GI number: 116690597

Start: 2851578

End: 2852219

Strand: Direct

Name: kynB [H]

Synonym: Bcen2424_2577

Alternate gene names: 116690597

Gene position: 2851578-2852219 (Clockwise)

Preceding gene: 116690595

Following gene: 116690598

Centisome position: 81.85

GC content: 70.25

Gene sequence:

>642_bases
ATGGACACACTCTGGGACATCTCGCCGCCGGTCAGCCCCGCCACCCCCGTGTGGCCGGGCGATACGCCAGTTGCCGTCGA
ACGCGTATGGCGGATGGAGGCCGGTTCGCCGGTCAACGTCGCGCGCCTGACGCTGTCGCCGCACACGGGCGCGCACTGCG
ACGCGCCGCTGCACTACGATGCCGACGGCGCGCCGATCGGCGCGGTGCCGCTCGATACCTATCTCGGCCCGTGCCGCGTG
ATTCATTGCATCGGCGCGTCGCCGGTCGTGCGGCCGGCCGATGTGGAAGCCGCGCTCGACGGCGTACCGCCGCGCGTGCT
GCTGCGCACGTATGCGCGCGCCGCGGTCGAACAATGGGACAGCAATTTCTGCGCGGTCGCACCCGATACCGTCGACCTGC
TCGCCGCGCACGGTGTGAAGCTGATCGGCATCGATACGCCGTCGCTCGACCCGCAGGAATCGAAGACGATGGACGCGCAT
CACCGCGTGCGCGCGCACCGGATGGCGATCCTCGAAGGCATCGTGCTCGACGACGTGCCGCCCGGCGACTACGAATTGAT
CGCGCTGCCGCTCAAATTCGCGACACTCGACGCGAGCCCCGTGCGCGCGGTGCTGCGCGCGCTGCCCGCGCACGCTTCCT
GA

Upstream 100 bases:

>100_bases
ATTATCTGCCAATCCGGCGGATTGTCCATGTTTATTTCGCAAGCACTTTCTGCGAGCGTCCACCTATCATTCGAAGGATC
GACTCACGCTTCGTCATGCC

Downstream 100 bases:

>100_bases
TTACCCGACCTACGACCCCACATCATGATGATCAAGACCCGTGAAGATGCGCTCGCGCTCGACCGCGACGACCCGCTGGC
CCCGCTGCGCGACCAGTTCG

Product: cyclase family protein

Products: NA

Alternate protein names: KFA; N-formylkynurenine formamidase [H]

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MDTLWDISPPVSPATPVWPGDTPVAVERVWRMEAGSPVNVARLTLSPHTGAHCDAPLHYDADGAPIGAVPLDTYLGPCRV
IHCIGASPVVRPADVEAALDGVPPRVLLRTYARAAVEQWDSNFCAVAPDTVDLLAAHGVKLIGIDTPSLDPQESKTMDAH
HRVRAHRMAILEGIVLDDVPPGDYELIALPLKFATLDASPVRAVLRALPAHAS

Sequences:

>Translated_213_residues
MDTLWDISPPVSPATPVWPGDTPVAVERVWRMEAGSPVNVARLTLSPHTGAHCDAPLHYDADGAPIGAVPLDTYLGPCRV
IHCIGASPVVRPADVEAALDGVPPRVLLRTYARAAVEQWDSNFCAVAPDTVDLLAAHGVKLIGIDTPSLDPQESKTMDAH
HRVRAHRMAILEGIVLDDVPPGDYELIALPLKFATLDASPVRAVLRALPAHAS
>Mature_213_residues
MDTLWDISPPVSPATPVWPGDTPVAVERVWRMEAGSPVNVARLTLSPHTGAHCDAPLHYDADGAPIGAVPLDTYLGPCRV
IHCIGASPVVRPADVEAALDGVPPRVLLRTYARAAVEQWDSNFCAVAPDTVDLLAAHGVKLIGIDTPSLDPQESKTMDAH
HRVRAHRMAILEGIVLDDVPPGDYELIALPLKFATLDASPVRAVLRALPAHAS

Specific function: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine [H]

COG id: COG1878

COG function: function code R; Predicted metal-dependent hydrolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kynB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017484
- InterPro:   IPR007325 [H]

Pfam domain/function: PF04199 Cyclase [H]

EC number: =3.5.1.9 [H]

Molecular weight: Translated: 22677; Mature: 22677

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTLWDISPPVSPATPVWPGDTPVAVERVWRMEAGSPVNVARLTLSPHTGAHCDAPLHYD
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCEEC
ADGAPIGAVPLDTYLGPCRVIHCIGASPVVRPADVEAALDGVPPRVLLRTYARAAVEQWD
CCCCCCCCCCHHHHCCHHHEEEECCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHC
SNFCAVAPDTVDLLAAHGVKLIGIDTPSLDPQESKTMDAHHRVRAHRMAILEGIVLDDVP
CCEEEECCCHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEECCCC
PGDYELIALPLKFATLDASPVRAVLRALPAHAS
CCCEEEEEEEEEEEECCCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDTLWDISPPVSPATPVWPGDTPVAVERVWRMEAGSPVNVARLTLSPHTGAHCDAPLHYD
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCEEC
ADGAPIGAVPLDTYLGPCRVIHCIGASPVVRPADVEAALDGVPPRVLLRTYARAAVEQWD
CCCCCCCCCCHHHHCCHHHEEEECCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHC
SNFCAVAPDTVDLLAAHGVKLIGIDTPSLDPQESKTMDAHHRVRAHRMAILEGIVLDDVP
CCEEEECCCHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEECCCC
PGDYELIALPLKFATLDASPVRAVLRALPAHAS
CCCEEEEEEEEEEEECCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA