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The map label for this gene is kdsB1 [H]

Identifier: 116690567

GI number: 116690567

Start: 2823204

End: 2823995

Strand: Direct

Name: kdsB1 [H]

Synonym: Bcen2424_2547

Alternate gene names: 116690567

Gene position: 2823204-2823995 (Clockwise)

Preceding gene: 116690566

Following gene: 116690568

Centisome position: 81.04

GC content: 70.45

Gene sequence:

>792_bases
ATGACTCACCCGCCCCCCTTCATCGCCGTCATTCCCGCCCGGCTCGCGTCGACGCGGCTCCCGAACAAGCCGCTCGCCGA
TCTCGGCGGCAAGCCGATGGTCGTGCGTGTCGCCGAGCGCGCGCGCGAAGCGGGCGCGCAACAGGTGCTCGTCGCGTCCG
ACGCGCAGAGCGTGCTCGACGCGGCGCGCGATCACGGCTTCGAAGCGGTGCTCACGCGCGCCGACCATCCGTCCGGCACC
GACCGGCTCGCGGAAGTCGCGGCGGCCTTCGGCTGGCGCGACGACACCGTCGTCGTCAACGTGCAGGGCGACGAGCCGCT
GATCGACCCCGTGCTCGTGCGCGACGTAGCGTCGCACCTGGCCGCGCATCCGGCGTGCGCGATCGCGACCGCCGCTCACC
CGATCCACGACGCGGCCGACGTGTTCAATCCGAACGTCGTGAAGGTCGCGCTCGACGCGCAGAGCGTCGCGCTGTACTTC
TCGCGCGCGCCGATTCCGTGGAGCCGCGACGCGTACCAGCCGCACTGGCCCGACGTCGCGGCCATGCCTGCACCGGCTTT
CCCGGTCTATCGGCACATCGGCCTCTATGCGTATCGCGCGCGTTTCCTGCGCACCTATCCGTCGCTCGCGCAGGCGCCAA
TCGAACAGGCCGAGCAGCTCGAACAGTTGCGCGCGCTGTGGCACGGCGAGCGCATCGCGGTGCTGATCACCGAATCCGCG
CCCGAAGCCGGCATCGATACGCCGGCCGATCTCGCGCGCGTGCAGGCCCTTTTTCAGCCGGGTTCAAAATAA

Upstream 100 bases:

>100_bases
CCGTTCGACACCGTGACGGCCCGGCCCCGGCCGGGCTGCCGCACTCGCCGGGCGCCCGGCTTCCGGCGTCGCCCGCCCCG
TTCTTCCCAGCGCTCCCCTG

Downstream 100 bases:

>100_bases
CCCGTGGCATAATCAGGCGATTGTGCGAGCCGTCCGCGACCAGCGCGTCCTCGCTTGACCCCGCCCGTGGCCCTGCCGGC
AGCCGCGCGTCGCCTCGGCC

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase 1; CKS 1; CMP-KDO synthase 1 [H]

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MTHPPPFIAVIPARLASTRLPNKPLADLGGKPMVVRVAERAREAGAQQVLVASDAQSVLDAARDHGFEAVLTRADHPSGT
DRLAEVAAAFGWRDDTVVVNVQGDEPLIDPVLVRDVASHLAAHPACAIATAAHPIHDAADVFNPNVVKVALDAQSVALYF
SRAPIPWSRDAYQPHWPDVAAMPAPAFPVYRHIGLYAYRARFLRTYPSLAQAPIEQAEQLEQLRALWHGERIAVLITESA
PEAGIDTPADLARVQALFQPGSK

Sequences:

>Translated_263_residues
MTHPPPFIAVIPARLASTRLPNKPLADLGGKPMVVRVAERAREAGAQQVLVASDAQSVLDAARDHGFEAVLTRADHPSGT
DRLAEVAAAFGWRDDTVVVNVQGDEPLIDPVLVRDVASHLAAHPACAIATAAHPIHDAADVFNPNVVKVALDAQSVALYF
SRAPIPWSRDAYQPHWPDVAAMPAPAFPVYRHIGLYAYRARFLRTYPSLAQAPIEQAEQLEQLRALWHGERIAVLITESA
PEAGIDTPADLARVQALFQPGSK
>Mature_262_residues
THPPPFIAVIPARLASTRLPNKPLADLGGKPMVVRVAERAREAGAQQVLVASDAQSVLDAARDHGFEAVLTRADHPSGTD
RLAEVAAAFGWRDDTVVVNVQGDEPLIDPVLVRDVASHLAAHPACAIATAAHPIHDAADVFNPNVVKVALDAQSVALYFS
RAPIPWSRDAYQPHWPDVAAMPAPAFPVYRHIGLYAYRARFLRTYPSLAQAPIEQAEQLEQLRALWHGERIAVLITESAP
EAGIDTPADLARVQALFQPGSK

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=250, Percent_Identity=52, Blast_Score=258, Evalue=3e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 28372; Mature: 28241

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHPPPFIAVIPARLASTRLPNKPLADLGGKPMVVRVAERAREAGAQQVLVASDAQSVLD
CCCCCCEEEEHHHHHHHCCCCCCCHHHCCCCCEEHHHHHHHHHCCHHEEEEHHHHHHHHH
AARDHGFEAVLTRADHPSGTDRLAEVAAAFGWRDDTVVVNVQGDEPLIDPVLVRDVASHL
HHHHCCHHEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHH
AAHPACAIATAAHPIHDAADVFNPNVVKVALDAQSVALYFSRAPIPWSRDAYQPHWPDVA
HHCCHHHHHHHCCCCHHHHHHCCCCEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCC
AMPAPAFPVYRHIGLYAYRARFLRTYPSLAQAPIEQAEQLEQLRALWHGERIAVLITESA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
PEAGIDTPADLARVQALFQPGSK
CCCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
THPPPFIAVIPARLASTRLPNKPLADLGGKPMVVRVAERAREAGAQQVLVASDAQSVLD
CCCCCEEEEHHHHHHHCCCCCCCHHHCCCCCEEHHHHHHHHHCCHHEEEEHHHHHHHHH
AARDHGFEAVLTRADHPSGTDRLAEVAAAFGWRDDTVVVNVQGDEPLIDPVLVRDVASHL
HHHHCCHHEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHH
AAHPACAIATAAHPIHDAADVFNPNVVKVALDAQSVALYFSRAPIPWSRDAYQPHWPDVA
HHCCHHHHHHHCCCCHHHHHHCCCCEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCC
AMPAPAFPVYRHIGLYAYRARFLRTYPSLAQAPIEQAEQLEQLRALWHGERIAVLITESA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
PEAGIDTPADLARVQALFQPGSK
CCCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA