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The map label for this gene is xseA [H]

Identifier: 116690564

GI number: 116690564

Start: 2820043

End: 2821425

Strand: Reverse

Name: xseA [H]

Synonym: Bcen2424_2544

Alternate gene names: 116690564

Gene position: 2821425-2820043 (Counterclockwise)

Preceding gene: 116690569

Following gene: 116690563

Centisome position: 80.98

GC content: 72.6

Gene sequence:

>1383_bases
ATGCTTTCCGATTCCCCTTTTTCCGCCCCCGGCGCCACCCGCGGCGGCGACGAAGTGATTCCCGTTTCGGCGCTCAATCG
TGCGATTTCGACGATGCTCGAGCGCTCGTTTCCGCTGTTATGGATTTCCGGCGAAGTGTCGAATTTCACGCGCGCCGCGA
GCGGCCACTGGTATTTCTCGATCAAGGACCAGCAGGCGCAGATGCGCTGCGTGATGTTCCGTGGCCGCGCCCAGTATGCG
GAATTCACGCCGCGCGAAGGCGACCGCATCGAGGTGCGCGCGGTCGTCACGATGTACGAGCCGCGCGGCGAAGTGCAGCT
CAACGTCGAAGCCGTGCGGCGCACCGGGCAGGGGCGCCTGTACGAGGCATTCCTGCGGCTGAAGGCGCAGCTCGAGGCCG
AGGGCCTGTTCGCCCCCGAGCGCAAGCGGCCGCTGCCGGCGCACCCGCGCGCGATCGGCATCGTCACGTCGCTGCAGGCC
GCCGCGCTGCGCGACGTGCTGACCACGCTCGCCCGGCGCGCGCCGCATATTCCGGTGATCGTCTATCCGGCCCCCGTGCA
GGGCGCCGGTTCCGCCGAAAAGCTCGTCGCGGCCGTGGCGACCGCGAATGCGCGGCGCGAGGTAGACGTGCTGCTGGTCT
GTCGCGGCGGCGGCTCGATCGAGGATCTGTGGTCGTTCAACGACGAAGCGCTGGCGCGCGCGATCGCGGCGAGCGAGCTG
CCGGTCGTCAGCGGCGTCGGGCACGAAACCGATTTCACGATCGCCGACTTCGCGGCCGACCTGCGCGCGCCGACGCCGAC
CGGCGCGGCCGAACTCGCGAGCCCGCAGCGCGCGCTGCTGCTGCGCGAGGTCGACGAGCGCCAGCGTGCGCTCGCGCGCG
GCATGGCGCGCCGGCTCGAACAGCGCGCGCAGCAGCTCGACTGGCTCGCGCGCCGGCTCGTGAGTCCGGCCGAGCGGCTG
CAGCGGCAGCGCACGCACGTCCAGCAGCTCGCGGCGCGGCTGGCGTCGGCGGCGTCGCGGCCGGTGCGCGATGCCCGTGC
GCGTTTCGCGCTCGCGCAGTTGCGCTGGCAGCGCGCGCGGCCCGATGCGTCGCAGGCGCGCCACGCGCTCGCGGGGCTGT
CGCAGCGTCTGGCCAGCGCGTTGCAGCGCCGTCACGAACGCGACACGGCGCGCGTGTCGGCCTGTGCCGCGCGGCTCGAG
GTGCTGAGCCCGCAGCGTACGCTCGAGCGCGGCTATGCGGCGCTGATCGATGCGCAGACGGGCCGTGCGGTGCGCGCGCC
GAACGCGCTGAAGCCGCAGCGGCGCCTGACCGTGCATCTCGCCGAAGGCTCGGCCGACGTGTCGCTCGCCGACGTGCAGC
CGCGGCTGACCGATACGATCTGA

Upstream 100 bases:

>100_bases
GAGTGTGGACACCTTCCGTGCGCGACGGCGAATACGGCGGCGCTGGACGCCGCGCGCGTGTCGGACTATCGTGACGCCGC
CAGCATTCATCCGACCGCCC

Downstream 100 bases:

>100_bases
CGCAAGAAGCGGCGCGCGAGACACGCGAGGATCGTCGCAACGCATGCGGCACGGCCGGGCACGAATGCTGCGCATCGTCC
GGTTCGTCCTGCCGGACGTC

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MLSDSPFSAPGATRGGDEVIPVSALNRAISTMLERSFPLLWISGEVSNFTRAASGHWYFSIKDQQAQMRCVMFRGRAQYA
EFTPREGDRIEVRAVVTMYEPRGEVQLNVEAVRRTGQGRLYEAFLRLKAQLEAEGLFAPERKRPLPAHPRAIGIVTSLQA
AALRDVLTTLARRAPHIPVIVYPAPVQGAGSAEKLVAAVATANARREVDVLLVCRGGGSIEDLWSFNDEALARAIAASEL
PVVSGVGHETDFTIADFAADLRAPTPTGAAELASPQRALLLREVDERQRALARGMARRLEQRAQQLDWLARRLVSPAERL
QRQRTHVQQLAARLASAASRPVRDARARFALAQLRWQRARPDASQARHALAGLSQRLASALQRRHERDTARVSACAARLE
VLSPQRTLERGYAALIDAQTGRAVRAPNALKPQRRLTVHLAEGSADVSLADVQPRLTDTI

Sequences:

>Translated_460_residues
MLSDSPFSAPGATRGGDEVIPVSALNRAISTMLERSFPLLWISGEVSNFTRAASGHWYFSIKDQQAQMRCVMFRGRAQYA
EFTPREGDRIEVRAVVTMYEPRGEVQLNVEAVRRTGQGRLYEAFLRLKAQLEAEGLFAPERKRPLPAHPRAIGIVTSLQA
AALRDVLTTLARRAPHIPVIVYPAPVQGAGSAEKLVAAVATANARREVDVLLVCRGGGSIEDLWSFNDEALARAIAASEL
PVVSGVGHETDFTIADFAADLRAPTPTGAAELASPQRALLLREVDERQRALARGMARRLEQRAQQLDWLARRLVSPAERL
QRQRTHVQQLAARLASAASRPVRDARARFALAQLRWQRARPDASQARHALAGLSQRLASALQRRHERDTARVSACAARLE
VLSPQRTLERGYAALIDAQTGRAVRAPNALKPQRRLTVHLAEGSADVSLADVQPRLTDTI
>Mature_460_residues
MLSDSPFSAPGATRGGDEVIPVSALNRAISTMLERSFPLLWISGEVSNFTRAASGHWYFSIKDQQAQMRCVMFRGRAQYA
EFTPREGDRIEVRAVVTMYEPRGEVQLNVEAVRRTGQGRLYEAFLRLKAQLEAEGLFAPERKRPLPAHPRAIGIVTSLQA
AALRDVLTTLARRAPHIPVIVYPAPVQGAGSAEKLVAAVATANARREVDVLLVCRGGGSIEDLWSFNDEALARAIAASEL
PVVSGVGHETDFTIADFAADLRAPTPTGAAELASPQRALLLREVDERQRALARGMARRLEQRAQQLDWLARRLVSPAERL
QRQRTHVQQLAARLASAASRPVRDARARFALAQLRWQRARPDASQARHALAGLSQRLASALQRRHERDTARVSACAARLE
VLSPQRTLERGYAALIDAQTGRAVRAPNALKPQRRLTVHLAEGSADVSLADVQPRLTDTI

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=440, Percent_Identity=42.2727272727273, Blast_Score=343, Evalue=2e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 50504; Mature: 50504

Theoretical pI: Translated: 11.38; Mature: 11.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSDSPFSAPGATRGGDEVIPVSALNRAISTMLERSFPLLWISGEVSNFTRAASGHWYFS
CCCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHCCCCEEEE
IKDQQAQMRCVMFRGRAQYAEFTPREGDRIEVRAVVTMYEPRGEVQLNVEAVRRTGQGRL
ECCCHHHHHHHHHCCCHHHHCCCCCCCCEEEEEEEEEEECCCCCEEEEHHHHHHCCCCHH
YEAFLRLKAQLEAEGLFAPERKRPLPAHPRAIGIVTSLQAAALRDVLTTLARRAPHIPVI
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
VYPAPVQGAGSAEKLVAAVATANARREVDVLLVCRGGGSIEDLWSFNDEALARAIAASEL
EECCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHCCCHHHHHHHHHHHCC
PVVSGVGHETDFTIADFAADLRAPTPTGAAELASPQRALLLREVDERQRALARGMARRLE
CEEECCCCCCCCHHHHHHHHHCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QRAQQLDWLARRLVSPAERLQRQRTHVQQLAARLASAASRPVRDARARFALAQLRWQRAR
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
PDASQARHALAGLSQRLASALQRRHERDTARVSACAARLEVLSPQRTLERGYAALIDAQT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHEEEECCC
GRAVRAPNALKPQRRLTVHLAEGSADVSLADVQPRLTDTI
CCEECCCCCCCCCCEEEEEEECCCCCEEEECCCCHHHCCC
>Mature Secondary Structure
MLSDSPFSAPGATRGGDEVIPVSALNRAISTMLERSFPLLWISGEVSNFTRAASGHWYFS
CCCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHCCCCEEEE
IKDQQAQMRCVMFRGRAQYAEFTPREGDRIEVRAVVTMYEPRGEVQLNVEAVRRTGQGRL
ECCCHHHHHHHHHCCCHHHHCCCCCCCCEEEEEEEEEEECCCCCEEEEHHHHHHCCCCHH
YEAFLRLKAQLEAEGLFAPERKRPLPAHPRAIGIVTSLQAAALRDVLTTLARRAPHIPVI
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
VYPAPVQGAGSAEKLVAAVATANARREVDVLLVCRGGGSIEDLWSFNDEALARAIAASEL
EECCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHCCCHHHHHHHHHHHCC
PVVSGVGHETDFTIADFAADLRAPTPTGAAELASPQRALLLREVDERQRALARGMARRLE
CEEECCCCCCCCHHHHHHHHHCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QRAQQLDWLARRLVSPAERLQRQRTHVQQLAARLASAASRPVRDARARFALAQLRWQRAR
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
PDASQARHALAGLSQRLASALQRRHERDTARVSACAARLEVLSPQRTLERGYAALIDAQT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHEEEECCC
GRAVRAPNALKPQRRLTVHLAEGSADVSLADVQPRLTDTI
CCEECCCCCCCCCCEEEEEEECCCCCEEEECCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA