| Definition | Burkholderia cenocepacia HI2424 chromosome 1, complete sequence. |
|---|---|
| Accession | NC_008542 |
| Length | 3,483,902 |
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The map label for this gene is icd [H]
Identifier: 116690543
GI number: 116690543
Start: 2795610
End: 2797838
Strand: Reverse
Name: icd [H]
Synonym: Bcen2424_2523
Alternate gene names: 116690543
Gene position: 2797838-2795610 (Counterclockwise)
Preceding gene: 116690544
Following gene: 116690541
Centisome position: 80.31
GC content: 66.08
Gene sequence:
>2229_bases ATGTCCACTTCGCCCAAGATCATCTACACCCTCACCGACGAAGCGCCGGCGCTCGCGACCTACTCGCTGCTGCCGATCGT CAAGGCCTTCACGCGTTCGTCCGGCGTCGCCGTCGAAACGCGCGACATCTCGCTCGCCGGCCGCATCATCGCGGCATTCG CAGACGTCCTGCCGTCGGAGCAGAAGGGTTCCGACGATCTGGCCGAGCTGGGCCAGCTCACGCTGAAGCCGGAAGCGAAC ATCATCAAGCTGCCGAACATCAGCGCATCGGTGCCGCAGCTGAAGGCCGCGATCGCCGAACTGCAGGCGCAGGGCTACGC GCTGCCGGCCTATCCGGAAGATCCGTCGACGGACGAAGAAAAGGCCGTCAAGGCGCGTTACGACAAGATCAAGGGCAGCG CGGTGAACCCGGTGCTGCGCGAAGGCAACTCCGACCGCCGCGCGCCGCTGTCGGTCAAGAACTACGCACGCAAGCATCCG CACAAGATGGGCGCGTGGAAGGCCACGTCGAAGGCGCACGTCGCGCACATGACCGAAGGTGACTTCTACGGCAGCGAGAA GTCGGCGCTGATCGCCGATGCCGGCAGCGTGAAGATCGAACTCACGACGACCGACGGCGCGAAGAAGGTGCTGAAGGAAA AGACGGCCGTGAAGGCCGGTGAAGTGATCGACGCATCGGTGATGAGCCGCAATGCGCTGCGCAGCTTCATCGAAGCGCAG ATCGCCGACGCGAAGGCGCAGGACGTGCTGTTCTCGGTGCACCTGAAGGCGACCATGATGAAGGTCTCGGACCCGATCCT GTTCGGTCACTTCGTGTCGGTGTTCTACCGCGACGCGCTCGCGAAGCACGCGGACGTGCTGGCGAAGGCCGGCTTCAACC CGAACAACGGGATCGGCGACCTGTACGCGCGCCTGAAGGACCTGCCGGCCGACACGCGCGAAGCGATCGAAGCCGACGTC AAGGCCGAGTACGCGGTGCGTCCGCGCCTCGCGATGGTCAACTCGGACAAGGGCATCACGAACCTGCACGTGCCGAGCGA CGTGATCGTCGACGCATCGATGCCGGCGATGATCCGCGATTCGGGCGGCATGTGGGGCCCGGACGGTCAGCTGTACGACG CGAAGGCCGTGATTCCGGACCGCTGCTACGCGGGCGTCTACCAGGCCGTGATCGAGGACTGCAAGCAGCACGGCGCGTTC GATCCGGTCACGATGGGCAGCGTGCCGAACGTCGGCCTGATGGCGCAGGCGGCCGAGGAATACGGTTCGCACGACAAGAC GTTCCAGATCCCGGCGGACGGCGTCGTGCGCGTCATCGACGAAGCCGGCAACGTGCTGCTCGAGCACGCGGTCGAGTCGG GCGACATCTGGCGCATGTGCCAGACGAAGGACGCACCGGTGCAGGACTGGGTCAAGCTCGCGGTCAACCGTGCCCGCGCG ACCGGCGCTCCGGCCGTGTTCTGGCTCGATCCGGCGCGCGCGCACGATGCGCAGATCATCGCGAAGGTCGAACGCTACCT GAAGGATCACGACACGAACGGCCTCGACATCCGGATCATGACGCCGGTCGACGCCACGCGTTTCTCGCTCGAGCGCATCC GCGCGGGCAAGGACACGATTTCGGTCACCGGCAACGTGCTGCGCGACTACCTGACCGACCTGTTCCCGATCATGGAACTC GGCACCAGCGCGAAGATGCTGTCGATCGTGCCGCTGATGGCCGGCGGCGGGATGTTCGAAACGGGTGCGGGCGGTTCCGC GCCGAAGCACGTGCAGCAGTTCGTCGAGGAAGGCTTCCTGCGCTGGGATTCGCTCGGCGAATTCCTCGCGCTGGCCGCGT CGCTCGAACACCTCGGCAACGCTTATCAAAACCCGAAGGCGCTCGTGCTCGCGAAGACGCTCGACCAGGCGACCGGCAAG TTCCTGGACGAGAACAAGTCGCCGGCGCGCAAGGTGGGTGGTCTCGACAACCGCGGCAGCCACTTCTACCTGTGCCTGTA CTGGGCGCAGGCGCTGGCCGAGCAGACCGAGGACGCCGCGCTGAAGGCGCAGTTCGAAGGCGTGGCGAAGACGCTGTCCG ACAACGAAGCGCGCATCCTGGAAGAACTGGCGGCCGCGCAAGGCAAGCCGCAGGCGATCGGCGGCTACTACCGTCCGAAC GTCGAGCTGACGAGCCAGGCCATGCGCCCGAGCGCGACGCTGAACGGCATCGTCGACGCGCTCGCCTGA
Upstream 100 bases:
>100_bases GGCTGAGCCGGCGCCCCTTTCGCGATCGACCCGGTCGCTCCCCGCCGGTTACCGCCGGCGCTCCTCAGTCCCTCAATCAC GTAGCAATGCTTTGACCACC
Downstream 100 bases:
>100_bases CGCCGGCCGCGCCAGCGCGCGAGCCCGTGCATGTGCCGGCGCGGCGGGTTGAACCGTTCGCCGCCCGGCACACAAGAAAA ACGCCCCGGTCGCCCGGGGC
Product: isocitrate dehydrogenase, NADP-dependent
Products: NA
Alternate protein names: IDH; Oxalosuccinate decarboxylase [H]
Number of amino acids: Translated: 742; Mature: 741
Protein sequence:
>742_residues MSTSPKIIYTLTDEAPALATYSLLPIVKAFTRSSGVAVETRDISLAGRIIAAFADVLPSEQKGSDDLAELGQLTLKPEAN IIKLPNISASVPQLKAAIAELQAQGYALPAYPEDPSTDEEKAVKARYDKIKGSAVNPVLREGNSDRRAPLSVKNYARKHP HKMGAWKATSKAHVAHMTEGDFYGSEKSALIADAGSVKIELTTTDGAKKVLKEKTAVKAGEVIDASVMSRNALRSFIEAQ IADAKAQDVLFSVHLKATMMKVSDPILFGHFVSVFYRDALAKHADVLAKAGFNPNNGIGDLYARLKDLPADTREAIEADV KAEYAVRPRLAMVNSDKGITNLHVPSDVIVDASMPAMIRDSGGMWGPDGQLYDAKAVIPDRCYAGVYQAVIEDCKQHGAF DPVTMGSVPNVGLMAQAAEEYGSHDKTFQIPADGVVRVIDEAGNVLLEHAVESGDIWRMCQTKDAPVQDWVKLAVNRARA TGAPAVFWLDPARAHDAQIIAKVERYLKDHDTNGLDIRIMTPVDATRFSLERIRAGKDTISVTGNVLRDYLTDLFPIMEL GTSAKMLSIVPLMAGGGMFETGAGGSAPKHVQQFVEEGFLRWDSLGEFLALAASLEHLGNAYQNPKALVLAKTLDQATGK FLDENKSPARKVGGLDNRGSHFYLCLYWAQALAEQTEDAALKAQFEGVAKTLSDNEARILEELAAAQGKPQAIGGYYRPN VELTSQAMRPSATLNGIVDALA
Sequences:
>Translated_742_residues MSTSPKIIYTLTDEAPALATYSLLPIVKAFTRSSGVAVETRDISLAGRIIAAFADVLPSEQKGSDDLAELGQLTLKPEAN IIKLPNISASVPQLKAAIAELQAQGYALPAYPEDPSTDEEKAVKARYDKIKGSAVNPVLREGNSDRRAPLSVKNYARKHP HKMGAWKATSKAHVAHMTEGDFYGSEKSALIADAGSVKIELTTTDGAKKVLKEKTAVKAGEVIDASVMSRNALRSFIEAQ IADAKAQDVLFSVHLKATMMKVSDPILFGHFVSVFYRDALAKHADVLAKAGFNPNNGIGDLYARLKDLPADTREAIEADV KAEYAVRPRLAMVNSDKGITNLHVPSDVIVDASMPAMIRDSGGMWGPDGQLYDAKAVIPDRCYAGVYQAVIEDCKQHGAF DPVTMGSVPNVGLMAQAAEEYGSHDKTFQIPADGVVRVIDEAGNVLLEHAVESGDIWRMCQTKDAPVQDWVKLAVNRARA TGAPAVFWLDPARAHDAQIIAKVERYLKDHDTNGLDIRIMTPVDATRFSLERIRAGKDTISVTGNVLRDYLTDLFPIMEL GTSAKMLSIVPLMAGGGMFETGAGGSAPKHVQQFVEEGFLRWDSLGEFLALAASLEHLGNAYQNPKALVLAKTLDQATGK FLDENKSPARKVGGLDNRGSHFYLCLYWAQALAEQTEDAALKAQFEGVAKTLSDNEARILEELAAAQGKPQAIGGYYRPN VELTSQAMRPSATLNGIVDALA >Mature_741_residues STSPKIIYTLTDEAPALATYSLLPIVKAFTRSSGVAVETRDISLAGRIIAAFADVLPSEQKGSDDLAELGQLTLKPEANI IKLPNISASVPQLKAAIAELQAQGYALPAYPEDPSTDEEKAVKARYDKIKGSAVNPVLREGNSDRRAPLSVKNYARKHPH KMGAWKATSKAHVAHMTEGDFYGSEKSALIADAGSVKIELTTTDGAKKVLKEKTAVKAGEVIDASVMSRNALRSFIEAQI ADAKAQDVLFSVHLKATMMKVSDPILFGHFVSVFYRDALAKHADVLAKAGFNPNNGIGDLYARLKDLPADTREAIEADVK AEYAVRPRLAMVNSDKGITNLHVPSDVIVDASMPAMIRDSGGMWGPDGQLYDAKAVIPDRCYAGVYQAVIEDCKQHGAFD PVTMGSVPNVGLMAQAAEEYGSHDKTFQIPADGVVRVIDEAGNVLLEHAVESGDIWRMCQTKDAPVQDWVKLAVNRARAT GAPAVFWLDPARAHDAQIIAKVERYLKDHDTNGLDIRIMTPVDATRFSLERIRAGKDTISVTGNVLRDYLTDLFPIMELG TSAKMLSIVPLMAGGGMFETGAGGSAPKHVQQFVEEGFLRWDSLGEFLALAASLEHLGNAYQNPKALVLAKTLDQATGKF LDENKSPARKVGGLDNRGSHFYLCLYWAQALAEQTEDAALKAQFEGVAKTLSDNEARILEELAAAQGKPQAIGGYYRPNV ELTSQAMRPSATLNGIVDALA
Specific function: Unknown
COG id: COG2838
COG function: function code C; Monomeric isocitrate dehydrogenase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the monomeric-type IDH family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001804 - InterPro: IPR004436 [H]
Pfam domain/function: PF03971 IDH [H]
EC number: =1.1.1.42 [H]
Molecular weight: Translated: 80011; Mature: 79880
Theoretical pI: Translated: 6.12; Mature: 6.12
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 2.6 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 3.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSTSPKIIYTLTDEAPALATYSLLPIVKAFTRSSGVAVETRDISLAGRIIAAFADVLPSE CCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHCCCC QKGSDDLAELGQLTLKPEANIIKLPNISASVPQLKAAIAELQAQGYALPAYPEDPSTDEE CCCCHHHHHHCCEEECCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH KAVKARYDKIKGSAVNPVLREGNSDRRAPLSVKNYARKHPHKMGAWKATSKAHVAHMTEG HHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCEEEECCC DFYGSEKSALIADAGSVKIELTTTDGAKKVLKEKTAVKAGEVIDASVMSRNALRSFIEAQ CCCCCCCCEEEEECCCEEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH IADAKAQDVLFSVHLKATMMKVSDPILFGHFVSVFYRDALAKHADVLAKAGFNPNNGIGD HHCCHHHHHEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH LYARLKDLPADTREAIEADVKAEYAVRPRLAMVNSDKGITNLHVPSDVIVDASMPAMIRD HHHHHHHCCCCHHHHHHHHCCHHHEECCEEEEEECCCCCEEEECCCCEEECCCCCCCEEC SGGMWGPDGQLYDAKAVIPDRCYAGVYQAVIEDCKQHGAFDPVTMGSVPNVGLMAQAAEE CCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCHHHHHHHHH YGSHDKTFQIPADGVVRVIDEAGNVLLEHAVESGDIWRMCQTKDAPVQDWVKLAVNRARA HCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEHHCCCCCCHHHHHHHHHHHHHC TGAPAVFWLDPARAHDAQIIAKVERYLKDHDTNGLDIRIMTPVDATRFSLERIRAGKDTI CCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCEE SVTGNVLRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMFETGAGGSAPKHVQQFVEEGFL EHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHH RWDSLGEFLALAASLEHLGNAYQNPKALVLAKTLDQATGKFLDENKSPARKVGGLDNRGS HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCCCHHHHHCCCCCCCC HFYLCLYWAQALAEQTEDAALKAQFEGVAKTLSDNEARILEELAAAQGKPQAIGGYYRPN EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCEECCC VELTSQAMRPSATLNGIVDALA CHHHHHHCCCCHHHHHHHHHCC >Mature Secondary Structure STSPKIIYTLTDEAPALATYSLLPIVKAFTRSSGVAVETRDISLAGRIIAAFADVLPSE CCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHCCCC QKGSDDLAELGQLTLKPEANIIKLPNISASVPQLKAAIAELQAQGYALPAYPEDPSTDEE CCCCHHHHHHCCEEECCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH KAVKARYDKIKGSAVNPVLREGNSDRRAPLSVKNYARKHPHKMGAWKATSKAHVAHMTEG HHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCEEEECCC DFYGSEKSALIADAGSVKIELTTTDGAKKVLKEKTAVKAGEVIDASVMSRNALRSFIEAQ CCCCCCCCEEEEECCCEEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH IADAKAQDVLFSVHLKATMMKVSDPILFGHFVSVFYRDALAKHADVLAKAGFNPNNGIGD HHCCHHHHHEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH LYARLKDLPADTREAIEADVKAEYAVRPRLAMVNSDKGITNLHVPSDVIVDASMPAMIRD HHHHHHHCCCCHHHHHHHHCCHHHEECCEEEEEECCCCCEEEECCCCEEECCCCCCCEEC SGGMWGPDGQLYDAKAVIPDRCYAGVYQAVIEDCKQHGAFDPVTMGSVPNVGLMAQAAEE CCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCHHHHHHHHH YGSHDKTFQIPADGVVRVIDEAGNVLLEHAVESGDIWRMCQTKDAPVQDWVKLAVNRARA HCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEHHCCCCCCHHHHHHHHHHHHHC TGAPAVFWLDPARAHDAQIIAKVERYLKDHDTNGLDIRIMTPVDATRFSLERIRAGKDTI CCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCEE SVTGNVLRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMFETGAGGSAPKHVQQFVEEGFL EHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHH RWDSLGEFLALAASLEHLGNAYQNPKALVLAKTLDQATGKFLDENKSPARKVGGLDNRGS HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCCCHHHHHCCCCCCCC HFYLCLYWAQALAEQTEDAALKAQFEGVAKTLSDNEARILEELAAAQGKPQAIGGYYRPN EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCEECCC VELTSQAMRPSATLNGIVDALA CHHHHHHCCCCHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 12005040; 4149369; 12467571 [H]