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The map label for this gene is rsmB [H]

Identifier: 116690529

GI number: 116690529

Start: 2778824

End: 2780089

Strand: Reverse

Name: rsmB [H]

Synonym: Bcen2424_2509

Alternate gene names: 116690529

Gene position: 2780089-2778824 (Counterclockwise)

Preceding gene: 116690530

Following gene: 116690528

Centisome position: 79.8

GC content: 69.59

Gene sequence:

>1266_bases
ATGAAGCTGCACGGATTCCTGATTGGCCAGACCGAAACCCTGCTCGCCGAGGTGCTGAAGTTCGCCGGCCCCGCCGACGC
GACGACGAGCCGGTTCTTCCGCGCGCACCCGAAGCTCGGGCATGCCGAGCGCGGCGTGATCGCCGAGGCCGTGTTCGCGG
TGCTGCGCCGGAAGATGGAGTTCTCGCATCTCGCCGAGAGCGGCACCGGCACGCCCGCGCGGCGTCTCACGCTGCTCGGC
CTGATGCAGACGATGGGGCGCAATGCGCTGAAGCCGTTCCTGTCCGACACCGAGTCCGCGTGGCTCGAGCACGTGTCGAA
GATCGATCCGGCGAGCCTGCCCGTGCGCATTCGCACGAACCTGCCCGACTGGATTCACCAGGCGCTGTCGGAGCGTTTCG
ACGCCGAGGAACTCGCGCAGCTCGCCGCTGCGCTGAACTACCCGGCGCCGCTCGACCTGCGTGCCAACGCGCAGAAGGCG
ACCCGCGACCAGGTGATCGAAGCGCTGCGCGTGAGCGGCATCGAAGCGGGCGCGACGCCGTTCGCGCCGTTCGGCGTGCG
CGTGGTCGGCAAGCCGGCGCTGACGCGCCTGAAGCTGTTCGAGGAAGGCGCGATCGAGGTGCAGGACGAAGGCAGCCAGC
TGCTGTGCTCGCTGGTCGCGCCGCGCCGCGGTGAAATGGTCGTCGATTTCTGCGCGGGCGCGGGCGGCAAGACGCTCGCA
CTCGGCGCGATGATGCGCTCGACCGGGCGCCTCTATGCGTTCGACATCTCGGAGAAGCGTCTCGCGAAGCTGAAGCCGCG
CCTCGCGCGCAGCGGGCTGTCGAACGTGAACCCGGTGCTGATCGACAGCGAGCACGACGCGAAGATCAAACGGCTCGCCG
GCAAGATCGACCGCGTGCTGGTCGATGCGCCGTGCAGCGGCCTCGGCACGCTGCGCCGCAATCCGGACCTGAAGTGGCGC
CAGACGCGCACGGCGATCGACGAGCTGACGCCGAAGCAGGCGTCGATCCTCGCGAGCGCCGCGCGGCTCGTGAAGAAGGG
CGGCCGGCTCGTCTACGCGACCTGCAGCGTGCTCGACGCCGAGAACGAGCGCATCGTCGAACAGTTCCTGGCCGATCATC
CGGAGTTCACGCTGGTGCCGGCGCAGCAGGTGCTGGCCGACCAGCGCATCGAGCTCGAGACGGGCGACTACCTGTCGCTG
TGGCCGCACCGTCACGCGACCGACGGCTTCTTCGCCGCGGTGCTCGAGCGCCGCGCCGCGCAGTAA

Upstream 100 bases:

>100_bases
AAGGGCGTCTGCGCCTCGAGGACGGTCGTGCAGTGGTCGCGCCCGAAGAGGCGCGCTGGATTTTCGCGGATCAACCGCAA
ACCGAAACGAGTGAGGGCGT

Downstream 100 bases:

>100_bases
CGACTGCCCGGACGGACGATGGAGAATTTGCAGAGCCGCCTGCTGTCGCACCGGCTGGAATCGGTGATTCGCGATTTCCA
CCAGCCGGTGATGATCTGGC

Product: Fmu (Sun) domain-containing protein

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MKLHGFLIGQTETLLAEVLKFAGPADATTSRFFRAHPKLGHAERGVIAEAVFAVLRRKMEFSHLAESGTGTPARRLTLLG
LMQTMGRNALKPFLSDTESAWLEHVSKIDPASLPVRIRTNLPDWIHQALSERFDAEELAQLAAALNYPAPLDLRANAQKA
TRDQVIEALRVSGIEAGATPFAPFGVRVVGKPALTRLKLFEEGAIEVQDEGSQLLCSLVAPRRGEMVVDFCAGAGGKTLA
LGAMMRSTGRLYAFDISEKRLAKLKPRLARSGLSNVNPVLIDSEHDAKIKRLAGKIDRVLVDAPCSGLGTLRRNPDLKWR
QTRTAIDELTPKQASILASAARLVKKGGRLVYATCSVLDAENERIVEQFLADHPEFTLVPAQQVLADQRIELETGDYLSL
WPHRHATDGFFAAVLERRAAQ

Sequences:

>Translated_421_residues
MKLHGFLIGQTETLLAEVLKFAGPADATTSRFFRAHPKLGHAERGVIAEAVFAVLRRKMEFSHLAESGTGTPARRLTLLG
LMQTMGRNALKPFLSDTESAWLEHVSKIDPASLPVRIRTNLPDWIHQALSERFDAEELAQLAAALNYPAPLDLRANAQKA
TRDQVIEALRVSGIEAGATPFAPFGVRVVGKPALTRLKLFEEGAIEVQDEGSQLLCSLVAPRRGEMVVDFCAGAGGKTLA
LGAMMRSTGRLYAFDISEKRLAKLKPRLARSGLSNVNPVLIDSEHDAKIKRLAGKIDRVLVDAPCSGLGTLRRNPDLKWR
QTRTAIDELTPKQASILASAARLVKKGGRLVYATCSVLDAENERIVEQFLADHPEFTLVPAQQVLADQRIELETGDYLSL
WPHRHATDGFFAAVLERRAAQ
>Mature_421_residues
MKLHGFLIGQTETLLAEVLKFAGPADATTSRFFRAHPKLGHAERGVIAEAVFAVLRRKMEFSHLAESGTGTPARRLTLLG
LMQTMGRNALKPFLSDTESAWLEHVSKIDPASLPVRIRTNLPDWIHQALSERFDAEELAQLAAALNYPAPLDLRANAQKA
TRDQVIEALRVSGIEAGATPFAPFGVRVVGKPALTRLKLFEEGAIEVQDEGSQLLCSLVAPRRGEMVVDFCAGAGGKTLA
LGAMMRSTGRLYAFDISEKRLAKLKPRLARSGLSNVNPVLIDSEHDAKIKRLAGKIDRVLVDAPCSGLGTLRRNPDLKWR
QTRTAIDELTPKQASILASAARLVKKGGRLVYATCSVLDAENERIVEQFLADHPEFTLVPAQQVLADQRIELETGDYLSL
WPHRHATDGFFAAVLERRAAQ

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=320, Percent_Identity=29.375, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI76150623, Length=320, Percent_Identity=29.375, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI32698918, Length=186, Percent_Identity=30.1075268817204, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI270288818, Length=238, Percent_Identity=32.3529411764706, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI270288816, Length=238, Percent_Identity=32.3529411764706, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI8922322, Length=238, Percent_Identity=32.3529411764706, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI23199998, Length=238, Percent_Identity=32.3529411764706, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI301336155, Length=257, Percent_Identity=28.7937743190661, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI39995082, Length=201, Percent_Identity=31.3432835820896, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI40316918, Length=154, Percent_Identity=34.4155844155844, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI11545785, Length=163, Percent_Identity=32.5153374233129, Blast_Score=65, Evalue=1e-10,
Organism=Escherichia coli, GI2367212, Length=259, Percent_Identity=32.8185328185328, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI87081985, Length=203, Percent_Identity=29.5566502463054, Blast_Score=92, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17536757, Length=295, Percent_Identity=28.8135593220339, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI115534021, Length=226, Percent_Identity=31.4159292035398, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71998419, Length=226, Percent_Identity=31.4159292035398, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI25143471, Length=290, Percent_Identity=29.6551724137931, Blast_Score=85, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6324268, Length=312, Percent_Identity=26.6025641025641, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6319447, Length=183, Percent_Identity=33.879781420765, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI22024126, Length=227, Percent_Identity=28.1938325991189, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21356579, Length=327, Percent_Identity=25.6880733944954, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21355201, Length=191, Percent_Identity=30.3664921465969, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24668781, Length=207, Percent_Identity=29.951690821256, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21356513, Length=207, Percent_Identity=29.951690821256, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19920494, Length=154, Percent_Identity=33.7662337662338, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 46114; Mature: 46114

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLHGFLIGQTETLLAEVLKFAGPADATTSRFFRAHPKLGHAERGVIAEAVFAVLRRKME
CCCCEEEECCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
FSHLAESGTGTPARRLTLLGLMQTMGRNALKPFLSDTESAWLEHVSKIDPASLPVRIRTN
HHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEECC
LPDWIHQALSERFDAEELAQLAAALNYPAPLDLRANAQKATRDQVIEALRVSGIEAGATP
CHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
FAPFGVRVVGKPALTRLKLFEEGAIEVQDEGSQLLCSLVAPRRGEMVVDFCAGAGGKTLA
CCCCCEEEECCHHHHHHHHHHCCCEEEECCHHHHHHHHHCCCCCCEEEEEECCCCCCHHH
LGAMMRSTGRLYAFDISEKRLAKLKPRLARSGLSNVNPVLIDSEHDAKIKRLAGKIDRVL
HHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHEE
VDAPCSGLGTLRRNPDLKWRQTRTAIDELTPKQASILASAARLVKKGGRLVYATCSVLDA
EECCCCCCHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEEHHCC
ENERIVEQFLADHPEFTLVPAQQVLADQRIELETGDYLSLWPHRHATDGFFAAVLERRAA
CHHHHHHHHHHCCCCEEEECHHHHHCCCCEEECCCCEEEECCCCCCCHHHHHHHHHHHCC
Q
C
>Mature Secondary Structure
MKLHGFLIGQTETLLAEVLKFAGPADATTSRFFRAHPKLGHAERGVIAEAVFAVLRRKME
CCCCEEEECCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
FSHLAESGTGTPARRLTLLGLMQTMGRNALKPFLSDTESAWLEHVSKIDPASLPVRIRTN
HHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEECC
LPDWIHQALSERFDAEELAQLAAALNYPAPLDLRANAQKATRDQVIEALRVSGIEAGATP
CHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
FAPFGVRVVGKPALTRLKLFEEGAIEVQDEGSQLLCSLVAPRRGEMVVDFCAGAGGKTLA
CCCCCEEEECCHHHHHHHHHHCCCEEEECCHHHHHHHHHCCCCCCEEEEEECCCCCCHHH
LGAMMRSTGRLYAFDISEKRLAKLKPRLARSGLSNVNPVLIDSEHDAKIKRLAGKIDRVL
HHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHEE
VDAPCSGLGTLRRNPDLKWRQTRTAIDELTPKQASILASAARLVKKGGRLVYATCSVLDA
EECCCCCCHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEEHHCC
ENERIVEQFLADHPEFTLVPAQQVLADQRIELETGDYLSLWPHRHATDGFFAAVLERRAA
CHHHHHHHHHHCCCCEEEECHHHHHCCCCEEECCCCEEEECCCCCCCHHHHHHHHHHHCC
Q
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]