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The map label for this gene is nadA [H]

Identifier: 116690526

GI number: 116690526

Start: 2774561

End: 2775697

Strand: Reverse

Name: nadA [H]

Synonym: Bcen2424_2506

Alternate gene names: 116690526

Gene position: 2775697-2774561 (Counterclockwise)

Preceding gene: 116690527

Following gene: 116690525

Centisome position: 79.67

GC content: 65.61

Gene sequence:

>1137_bases
ATGCAATCGACGATCAAACCCGTCGAGTACGACCGGCCCGTCGCAGCAGGGACCGTGTGCGGCGTCGGACAGGCATGGGC
CAAGGTGCCCGACGCGCCGTCCGCCGAGGAGCGCGCTGCGCTGAAGGCACGCATCAAGGCGCTGCTCGCCCGTGAAAAGG
CCGTGCTCGTCGCCCACTACTACGTGGATGCCGAACTGCAGGAACTGGCCGACGAAACGGGCGGCTGCGTGGCCGATTCG
CTCGAAATGGCCCGCTTCGGCCGTGACCACGACGCGCAGACGCTGATCGTTGCCGGCGTGCGCTTCATGGGCGAAACCGC
GAAGATCCTGAGCCCGAACAAACGGATCCTGATGCCCGATCTCGATGCGACCTGTTCGCTCGACCTCGGCTGCCCGGTCG
ACGAATTCTCGGCATTCTGCGATGCGCATCCGGACCGTACCGTCGTCGTCTACGCGAACACCAGCGCTGCCGTGAAGGCG
CGCGCGGACTGGATGGTCACGTCGTCGATCGGTCTCGAGATCGTGGCCGACCTGCACGCGCGCGGCGAAAAGATCATCTG
GGCGCCGGACCGTCATCTCGGCAGCTATATCCAGAAGAAGACCGGCGCGGATATGCTGCTGTGGCAGGGCTCGTGTCTCG
TCCACGACGAATTCAAGGGCATCGAGCTCGACCTGCTGCGCGCCGAATATCCGGACGCGAAGGTGCTCGTCCACCCCGAG
TCGCCGGAAAACGTCGTCGCGCAGGCCGATGTCGTCGGTTCGACCACGCAATTGATCGACGCGGCCGTCAAGTTCGATGC
GAAGCGTTTCATCGTCGCGACGGATCTCGGCATCCTGCACAAGATGCAGCTGGCCGCGCCCGGCAAGACCTTCATTGCCG
CGCCGACGGCCGGCAACAGCGCGACCTGCAAGAGCTGCGCGCACTGCCCGTGGATGGCGATGAACGGCCTCGCGAACCTC
GCCGACGTGCTCGAACGCGGTCACAACGAGATCTTCGTCGATCCCGCGATCGGCGAGCGTGCGCGTTTGCCGATCGACCG
GATGCTCGAATTCGCGGCTGCGCACAAGAAGCGCGTGCAGGCGAGCGGCGATCTGCAGCGCGACCAGTCGCTGTTCGCGA
ACGTGGGGGCGGCATGA

Upstream 100 bases:

>100_bases
GGGCATGAGTAAGCGCTGAAGCGCTAACTCCTGCCGACCGCGAAGCATGGGGCCGGAGTAAGTGCTAAAGCACTCACTCC
GGCCGACAGGAGATATGGAG

Downstream 100 bases:

>100_bases
GCAACGCCGTATCCCCGCTGTTCGAAGCCGTCCGCGCCCAATACGGCGCGGCATTCGACGAAGCGATCGCGCGTAACGTG
GCCGACGCGATCGCCGAAGA

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MQSTIKPVEYDRPVAAGTVCGVGQAWAKVPDAPSAEERAALKARIKALLAREKAVLVAHYYVDAELQELADETGGCVADS
LEMARFGRDHDAQTLIVAGVRFMGETAKILSPNKRILMPDLDATCSLDLGCPVDEFSAFCDAHPDRTVVVYANTSAAVKA
RADWMVTSSIGLEIVADLHARGEKIIWAPDRHLGSYIQKKTGADMLLWQGSCLVHDEFKGIELDLLRAEYPDAKVLVHPE
SPENVVAQADVVGSTTQLIDAAVKFDAKRFIVATDLGILHKMQLAAPGKTFIAAPTAGNSATCKSCAHCPWMAMNGLANL
ADVLERGHNEIFVDPAIGERARLPIDRMLEFAAAHKKRVQASGDLQRDQSLFANVGAA

Sequences:

>Translated_378_residues
MQSTIKPVEYDRPVAAGTVCGVGQAWAKVPDAPSAEERAALKARIKALLAREKAVLVAHYYVDAELQELADETGGCVADS
LEMARFGRDHDAQTLIVAGVRFMGETAKILSPNKRILMPDLDATCSLDLGCPVDEFSAFCDAHPDRTVVVYANTSAAVKA
RADWMVTSSIGLEIVADLHARGEKIIWAPDRHLGSYIQKKTGADMLLWQGSCLVHDEFKGIELDLLRAEYPDAKVLVHPE
SPENVVAQADVVGSTTQLIDAAVKFDAKRFIVATDLGILHKMQLAAPGKTFIAAPTAGNSATCKSCAHCPWMAMNGLANL
ADVLERGHNEIFVDPAIGERARLPIDRMLEFAAAHKKRVQASGDLQRDQSLFANVGAA
>Mature_378_residues
MQSTIKPVEYDRPVAAGTVCGVGQAWAKVPDAPSAEERAALKARIKALLAREKAVLVAHYYVDAELQELADETGGCVADS
LEMARFGRDHDAQTLIVAGVRFMGETAKILSPNKRILMPDLDATCSLDLGCPVDEFSAFCDAHPDRTVVVYANTSAAVKA
RADWMVTSSIGLEIVADLHARGEKIIWAPDRHLGSYIQKKTGADMLLWQGSCLVHDEFKGIELDLLRAEYPDAKVLVHPE
SPENVVAQADVVGSTTQLIDAAVKFDAKRFIVATDLGILHKMQLAAPGKTFIAAPTAGNSATCKSCAHCPWMAMNGLANL
ADVLERGHNEIFVDPAIGERARLPIDRMLEFAAAHKKRVQASGDLQRDQSLFANVGAA

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=326, Percent_Identity=65.0306748466258, Blast_Score=444, Evalue=1e-126,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 40752; Mature: 40752

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSTIKPVEYDRPVAAGTVCGVGQAWAKVPDAPSAEERAALKARIKALLAREKAVLVAHY
CCCCCCCCCCCCCCCCCCHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEE
YVDAELQELADETGGCVADSLEMARFGRDHDAQTLIVAGVRFMGETAKILSPNKRILMPD
EECHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEHHHHHHCCCHHHCCCCCEEEECC
LDATCSLDLGCPVDEFSAFCDAHPDRTVVVYANTSAAVKARADWMVTSSIGLEIVADLHA
CCCCEEEECCCCHHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEECCCCCEEEEHHHC
RGEKIIWAPDRHLGSYIQKKTGADMLLWQGSCLVHDEFKGIELDLLRAEYPDAKVLVHPE
CCCEEEECCCHHHHHHHHHHCCCCEEEECCCEEEECCCCCCEEEEEECCCCCCEEEECCC
SPENVVAQADVVGSTTQLIDAAVKFDAKRFIVATDLGILHKMQLAAPGKTFIAAPTAGNS
CCCCCEEEHHHCCCHHHHHHHHHHHCCCEEEEEECHHHHHHHHHCCCCCEEEEECCCCCC
ATCKSCAHCPWMAMNGLANLADVLERGHNEIFVDPAIGERARLPIDRMLEFAAAHKKRVQ
CCHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
ASGDLQRDQSLFANVGAA
CCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MQSTIKPVEYDRPVAAGTVCGVGQAWAKVPDAPSAEERAALKARIKALLAREKAVLVAHY
CCCCCCCCCCCCCCCCCCHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEE
YVDAELQELADETGGCVADSLEMARFGRDHDAQTLIVAGVRFMGETAKILSPNKRILMPD
EECHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEHHHHHHCCCHHHCCCCCEEEECC
LDATCSLDLGCPVDEFSAFCDAHPDRTVVVYANTSAAVKARADWMVTSSIGLEIVADLHA
CCCCEEEECCCCHHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEECCCCCEEEEHHHC
RGEKIIWAPDRHLGSYIQKKTGADMLLWQGSCLVHDEFKGIELDLLRAEYPDAKVLVHPE
CCCEEEECCCHHHHHHHHHHCCCCEEEECCCEEEECCCCCCEEEEEECCCCCCEEEECCC
SPENVVAQADVVGSTTQLIDAAVKFDAKRFIVATDLGILHKMQLAAPGKTFIAAPTAGNS
CCCCCEEEHHHCCCHHHHHHHHHHHCCCEEEEEECHHHHHHHHHCCCCCEEEEECCCCCC
ATCKSCAHCPWMAMNGLANLADVLERGHNEIFVDPAIGERARLPIDRMLEFAAAHKKRVQ
CCHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
ASGDLQRDQSLFANVGAA
CCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA