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The map label for this gene is argD [H]

Identifier: 116690511

GI number: 116690511

Start: 2761454

End: 2762638

Strand: Direct

Name: argD [H]

Synonym: Bcen2424_2491

Alternate gene names: 116690511

Gene position: 2761454-2762638 (Clockwise)

Preceding gene: 116690510

Following gene: 116690512

Centisome position: 79.26

GC content: 64.89

Gene sequence:

>1185_bases
ATGCCCCTGAACGATTATCCGATCGACTCGCTGATGTACATCACGAACCGCCCCGACATCGTGTTTACGCACGGCAAGGG
TTCGTGGCTCTACGATCACACGGGCAAGCGCTATCTGGACTTCATCCAGGGCTGGGCCGTCAACAGCCTGGGCCACTGCA
ACGACGGTATCGTCGAGGCGCTGAAGACGCAGGCCGAAAAGCTGCTGAACCCGTCGCCAGCGTTCTACAACGAACCGATG
GCGAAGCTCGCGGGTCTGCTCACGCAGCACAGCGTGTTCGACAAGGTGTTCTTCACGAACAGCGGCGCCGAGGCGAACGA
AGGCGCGATCAAGCTCGCGCGCAAGTGGGGCCGCAAGTACAAGAACGGCGCATACGAGATCATCACGTTCGACCACAGCT
TCCACGGCCGCACGCTCGCGACGATGTCGGCCAGCGGCAAGCCGGGCTGGGACACGATCTACGCGCCGCAGGTGCCGGGC
TTCCCGAAGGCCGAGCTGAACAACATCGAGTCGGTCGAGAAGCTGATCACCGACAAGACCGTCGCGGTGATGCTCGAGCC
GATCCAGGGCGAAGGCGGCGTGATCCCGGCCACGCGTGAATTCATGCAGGCGCTGCGCGCGCTGACGAAGCAGCACAACC
TGCTGCTGATCGTCGACGAAGTGCAAAGCGGTTGCGGCCGCGCGGGCAAGCTGTTCGCGTACGAGCTGTCCGGCATCGAG
CCGGACGTCATGACGCTCGCGAAGGGCATCGGCGGCGGCGCACCGCTCGGCGCGCTGCTGTCGAAAGCCGACGTCGCGGT
GTTCGAGGCCGGCGACCAGGGCGGTACGTACAACGGCAACCCGCTGATGACGGCGGTCGGCTATTCGGTGATCTCGCAGC
TCGTCGCACCCGGCTTCCTCGAAGGCGTGCGTGCGCGCAGCGAGTATCTGAAGCGCAAGCTGCTCGAACTGTCGGAGGAG
CGCGGCTTCGAGGGCGAACGCGGCGAAGGCCTGCTGCGCGCGCTGCTGCTCGGCAAGGACATCGGCCCGCAGATCGTCGA
GAAGGCGCGCGACATGCAGCCCGACGGCCTGCTGCTGAACGCCGCACGGCCGAACCTGCTGCGCTTCATGCCTGCCCTGA
ACGTGACGACCGAAGAAATCGACCAGATGATGGCGATGCTGCGGTCGATCCTCGACACGCTGTAA

Upstream 100 bases:

>100_bases
CTTCACCGGTTACGCACAAGCTGTTCGACCCACCAGCCACGGCCTTCCGTGGCTTTTTTATTGCCCGTTTCCCTTTCAAC
GCCCGCTGGAGTCTGCTGCC

Downstream 100 bases:

>100_bases
GGAGACCGTCGCGATGGATGCCGCCGCCGATGCTGTCGCTATCCGCCCGTTCGAACGCGCCGACACCGATGCCGTGCTCG
CGGTATGGCGCGACGCGTTC

Product: acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MPLNDYPIDSLMYITNRPDIVFTHGKGSWLYDHTGKRYLDFIQGWAVNSLGHCNDGIVEALKTQAEKLLNPSPAFYNEPM
AKLAGLLTQHSVFDKVFFTNSGAEANEGAIKLARKWGRKYKNGAYEIITFDHSFHGRTLATMSASGKPGWDTIYAPQVPG
FPKAELNNIESVEKLITDKTVAVMLEPIQGEGGVIPATREFMQALRALTKQHNLLLIVDEVQSGCGRAGKLFAYELSGIE
PDVMTLAKGIGGGAPLGALLSKADVAVFEAGDQGGTYNGNPLMTAVGYSVISQLVAPGFLEGVRARSEYLKRKLLELSEE
RGFEGERGEGLLRALLLGKDIGPQIVEKARDMQPDGLLLNAARPNLLRFMPALNVTTEEIDQMMAMLRSILDTL

Sequences:

>Translated_394_residues
MPLNDYPIDSLMYITNRPDIVFTHGKGSWLYDHTGKRYLDFIQGWAVNSLGHCNDGIVEALKTQAEKLLNPSPAFYNEPM
AKLAGLLTQHSVFDKVFFTNSGAEANEGAIKLARKWGRKYKNGAYEIITFDHSFHGRTLATMSASGKPGWDTIYAPQVPG
FPKAELNNIESVEKLITDKTVAVMLEPIQGEGGVIPATREFMQALRALTKQHNLLLIVDEVQSGCGRAGKLFAYELSGIE
PDVMTLAKGIGGGAPLGALLSKADVAVFEAGDQGGTYNGNPLMTAVGYSVISQLVAPGFLEGVRARSEYLKRKLLELSEE
RGFEGERGEGLLRALLLGKDIGPQIVEKARDMQPDGLLLNAARPNLLRFMPALNVTTEEIDQMMAMLRSILDTL
>Mature_393_residues
PLNDYPIDSLMYITNRPDIVFTHGKGSWLYDHTGKRYLDFIQGWAVNSLGHCNDGIVEALKTQAEKLLNPSPAFYNEPMA
KLAGLLTQHSVFDKVFFTNSGAEANEGAIKLARKWGRKYKNGAYEIITFDHSFHGRTLATMSASGKPGWDTIYAPQVPGF
PKAELNNIESVEKLITDKTVAVMLEPIQGEGGVIPATREFMQALRALTKQHNLLLIVDEVQSGCGRAGKLFAYELSGIEP
DVMTLAKGIGGGAPLGALLSKADVAVFEAGDQGGTYNGNPLMTAVGYSVISQLVAPGFLEGVRARSEYLKRKLLELSEER
GFEGERGEGLLRALLLGKDIGPQIVEKARDMQPDGLLLNAARPNLLRFMPALNVTTEEIDQMMAMLRSILDTL

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=381, Percent_Identity=31.758530183727, Blast_Score=204, Evalue=9e-53,
Organism=Homo sapiens, GI284507298, Length=301, Percent_Identity=30.8970099667774, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI13994255, Length=427, Percent_Identity=27.4004683840749, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI37574042, Length=416, Percent_Identity=28.8461538461538, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI24119277, Length=417, Percent_Identity=27.0983213429257, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI226442705, Length=416, Percent_Identity=28.125, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI226442709, Length=386, Percent_Identity=29.0155440414508, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI188536080, Length=429, Percent_Identity=23.7762237762238, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI38679950, Length=429, Percent_Identity=23.7762237762238, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI38679946, Length=429, Percent_Identity=23.7762237762238, Blast_Score=86, Evalue=6e-17,
Organism=Escherichia coli, GI1788044, Length=359, Percent_Identity=44.5682451253482, Blast_Score=296, Evalue=1e-81,
Organism=Escherichia coli, GI1789759, Length=368, Percent_Identity=41.5760869565217, Blast_Score=276, Evalue=2e-75,
Organism=Escherichia coli, GI1789016, Length=398, Percent_Identity=32.1608040201005, Blast_Score=174, Evalue=6e-45,
Organism=Escherichia coli, GI145693181, Length=391, Percent_Identity=30.9462915601023, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1787560, Length=398, Percent_Identity=31.1557788944724, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1786349, Length=332, Percent_Identity=31.9277108433735, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1786991, Length=311, Percent_Identity=28.9389067524116, Blast_Score=96, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI25144271, Length=380, Percent_Identity=32.8947368421053, Blast_Score=218, Evalue=5e-57,
Organism=Caenorhabditis elegans, GI32564660, Length=417, Percent_Identity=28.7769784172662, Blast_Score=155, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI25144274, Length=276, Percent_Identity=32.9710144927536, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI71992977, Length=416, Percent_Identity=28.3653846153846, Blast_Score=131, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI71981843, Length=159, Percent_Identity=32.0754716981132, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17541228, Length=349, Percent_Identity=25.5014326647564, Blast_Score=84, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324432, Length=401, Percent_Identity=33.9152119700748, Blast_Score=212, Evalue=8e-56,
Organism=Saccharomyces cerevisiae, GI6323470, Length=397, Percent_Identity=31.2342569269521, Blast_Score=186, Evalue=5e-48,
Organism=Saccharomyces cerevisiae, GI6321456, Length=424, Percent_Identity=25.2358490566038, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6324386, Length=462, Percent_Identity=25.1082251082251, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI21357415, Length=378, Percent_Identity=33.3333333333333, Blast_Score=212, Evalue=4e-55,
Organism=Drosophila melanogaster, GI161085790, Length=415, Percent_Identity=27.2289156626506, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28574759, Length=410, Percent_Identity=27.5609756097561, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI21356575, Length=427, Percent_Identity=26.6978922716628, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI281366494, Length=293, Percent_Identity=25.938566552901, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24667139, Length=293, Percent_Identity=25.938566552901, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24667143, Length=293, Percent_Identity=25.938566552901, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43030; Mature: 42899

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS00599 AA_TRANSFER_CLASS_2 ; PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLNDYPIDSLMYITNRPDIVFTHGKGSWLYDHTGKRYLDFIQGWAVNSLGHCNDGIVEA
CCCCCCCCCCEEEEECCCCEEEECCCCCEEECCCCHHHHHHHHHHHCCCCCCCCHHHHHH
LKTQAEKLLNPSPAFYNEPMAKLAGLLTQHSVFDKVFFTNSGAEANEGAIKLARKWGRKY
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHH
KNGAYEIITFDHSFHGRTLATMSASGKPGWDTIYAPQVPGFPKAELNNIESVEKLITDKT
CCCCEEEEEECCCCCCCEEEEEECCCCCCCCCEECCCCCCCCCHHHCCHHHHHHHHHCCE
VAVMLEPIQGEGGVIPATREFMQALRALTKQHNLLLIVDEVQSGCGRAGKLFAYELSGIE
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEHHHHCCCCCCCEEEEECCCCC
PDVMTLAKGIGGGAPLGALLSKADVAVFEAGDQGGTYNGNPLMTAVGYSVISQLVAPGFL
HHHHHHHHHCCCCCCHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCHHH
EGVRARSEYLKRKLLELSEERGFEGERGEGLLRALLLGKDIGPQIVEKARDMQPDGLLLN
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEE
AARPNLLRFMPALNVTTEEIDQMMAMLRSILDTL
CCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
PLNDYPIDSLMYITNRPDIVFTHGKGSWLYDHTGKRYLDFIQGWAVNSLGHCNDGIVEA
CCCCCCCCCEEEEECCCCEEEECCCCCEEECCCCHHHHHHHHHHHCCCCCCCCHHHHHH
LKTQAEKLLNPSPAFYNEPMAKLAGLLTQHSVFDKVFFTNSGAEANEGAIKLARKWGRKY
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHH
KNGAYEIITFDHSFHGRTLATMSASGKPGWDTIYAPQVPGFPKAELNNIESVEKLITDKT
CCCCEEEEEECCCCCCCEEEEEECCCCCCCCCEECCCCCCCCCHHHCCHHHHHHHHHCCE
VAVMLEPIQGEGGVIPATREFMQALRALTKQHNLLLIVDEVQSGCGRAGKLFAYELSGIE
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEHHHHCCCCCCCEEEEECCCCC
PDVMTLAKGIGGGAPLGALLSKADVAVFEAGDQGGTYNGNPLMTAVGYSVISQLVAPGFL
HHHHHHHHHCCCCCCHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCHHH
EGVRARSEYLKRKLLELSEERGFEGERGEGLLRALLLGKDIGPQIVEKARDMQPDGLLLN
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEE
AARPNLLRFMPALNVTTEEIDQMMAMLRSILDTL
CCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]