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The map label for this gene is lysN [H]

Identifier: 116690371

GI number: 116690371

Start: 2613040

End: 2614221

Strand: Direct

Name: lysN [H]

Synonym: Bcen2424_2351

Alternate gene names: 116690371

Gene position: 2613040-2614221 (Clockwise)

Preceding gene: 116690370

Following gene: 116690372

Centisome position: 75.0

GC content: 69.71

Gene sequence:

>1182_bases
ATGAATCCGAGCGACCTGCATCCGCCGCACTGGCAGCTTTCCGAACGCGCCCGCAAGCTGACGAGCTCGGCGATCCGCGA
GATCCTGAAGGTCACGGAACGCCCCGAGGTCATCTCGTTCGCCGGCGGCCTGCCCGCCCCCGCGACGTTCCCGGCCGAAC
GCATGCGCGCCGCCGCCGACCGCGTGCTGCGCGATGCGCCGGCCGCCGCACTCCAGTACAGCGCGACCGAAGGCTACCTG
CCGCTGCGCGAGTGGATCGCCGAGCGCTACAGCGTGCGCGTGTCGCAGGTGCTGATCACGACCGGCTCGCAGCAGGCGCT
CGACCTGCTCGGCAAGGCGCTGATCGACCCGAACAGCCCGATCCTCGTCGAAACCCCGACCTACCTCGGCGCGCTGCAAT
CGTTCTCGCTGTACGAGCCGCGCTACGTGCAGGTGCCGACCGACGAGCAGGGCCTGCTGCCGGAAGGCCTCACGCCCGAA
CTCACGCAAGGCGCGCGGCTGCTGTACGCGCAGCCGAACTTCCAGAACCCGACCGGCCGCCGCCTGCCCGTCGAGCGCCG
CCGTGCGCTCGCCGCGTTCGCGCAGACGAGCCCGTTCCCGGTGCTGGAGGACGATCCGTACGGCGCGCTGAACTACCAGG
GCGAGCCGCTGCCGACGATGCTGTCGATGGCGCCCGACCACGTCGTGCATCTCGGCACGTTCTCGAAGGTGCTCGCGCCG
GGCCTGCGGATCGGCTACATCATCGCGCCCGAGGAACTCCACTTCAAGCTCGTGCAGGCCAAGCAGGCCACCGACCTGCA
CACGCCGACGCTCACGCAGCGCATCGCGCACGAAGTGATCAAGGACGGCTTCCTCGACGAGCACATCCCGACGATCCGCG
AGCTGTACAGCGCGCAGTGCGACGCGATGCTCGGCGCGCTCACGCGCCACATGCCGGCAGGCGTCACGTGGAACCGCCCG
GAAGGCGGGATGTTCATCTGGGTGAACCTGCCCGCGCAGATCGACAGCATGAAGCTGCTCGCCGCGGCCGTCGACAACCA
CGTCGCCTTCGTGCCGGGCGCGCCGTTCTTCGCGGAAAACGCGCAGCAGAACACGCTGCGCCTGTCGTTCGTGACGGTGC
CGCCCGAGAAGATCGAGGAAGGCGTCGCGCGCCTCGGCAAGCTGCTGCGCGAGCGCCTCTGA

Upstream 100 bases:

>100_bases
CGAAGGCGCCATCGTGCTCGCGCTCGCCCACCCGGCGGCGTCGAAGCGATCCGCCTGATCGACCTTTCTTGACTGACCAC
GATATCCGAACGAGGAGACT

Downstream 100 bases:

>100_bases
TCCCCTTTTTCCTGTCACGACTCTCTACGAGGAATCGAACACATGGCTAACGTCTACGACAAACTGAAGTCGCTCGGCAT
CGAGCTCCCGACCGCCGGCG

Product: aminotransferase, class I and II

Products: NA

Alternate protein names: 2-aminoadipate aminotransferase; Alpha-aminoadipate aminotransferase; AAA-AT; AadAT [H]

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MNPSDLHPPHWQLSERARKLTSSAIREILKVTERPEVISFAGGLPAPATFPAERMRAAADRVLRDAPAAALQYSATEGYL
PLREWIAERYSVRVSQVLITTGSQQALDLLGKALIDPNSPILVETPTYLGALQSFSLYEPRYVQVPTDEQGLLPEGLTPE
LTQGARLLYAQPNFQNPTGRRLPVERRRALAAFAQTSPFPVLEDDPYGALNYQGEPLPTMLSMAPDHVVHLGTFSKVLAP
GLRIGYIIAPEELHFKLVQAKQATDLHTPTLTQRIAHEVIKDGFLDEHIPTIRELYSAQCDAMLGALTRHMPAGVTWNRP
EGGMFIWVNLPAQIDSMKLLAAAVDNHVAFVPGAPFFAENAQQNTLRLSFVTVPPEKIEEGVARLGKLLRERL

Sequences:

>Translated_393_residues
MNPSDLHPPHWQLSERARKLTSSAIREILKVTERPEVISFAGGLPAPATFPAERMRAAADRVLRDAPAAALQYSATEGYL
PLREWIAERYSVRVSQVLITTGSQQALDLLGKALIDPNSPILVETPTYLGALQSFSLYEPRYVQVPTDEQGLLPEGLTPE
LTQGARLLYAQPNFQNPTGRRLPVERRRALAAFAQTSPFPVLEDDPYGALNYQGEPLPTMLSMAPDHVVHLGTFSKVLAP
GLRIGYIIAPEELHFKLVQAKQATDLHTPTLTQRIAHEVIKDGFLDEHIPTIRELYSAQCDAMLGALTRHMPAGVTWNRP
EGGMFIWVNLPAQIDSMKLLAAAVDNHVAFVPGAPFFAENAQQNTLRLSFVTVPPEKIEEGVARLGKLLRERL
>Mature_393_residues
MNPSDLHPPHWQLSERARKLTSSAIREILKVTERPEVISFAGGLPAPATFPAERMRAAADRVLRDAPAAALQYSATEGYL
PLREWIAERYSVRVSQVLITTGSQQALDLLGKALIDPNSPILVETPTYLGALQSFSLYEPRYVQVPTDEQGLLPEGLTPE
LTQGARLLYAQPNFQNPTGRRLPVERRRALAAFAQTSPFPVLEDDPYGALNYQGEPLPTMLSMAPDHVVHLGTFSKVLAP
GLRIGYIIAPEELHFKLVQAKQATDLHTPTLTQRIAHEVIKDGFLDEHIPTIRELYSAQCDAMLGALTRHMPAGVTWNRP
EGGMFIWVNLPAQIDSMKLLAAAVDNHVAFVPGAPFFAENAQQNTLRLSFVTVPPEKIEEGVARLGKLLRERL

Specific function: Catalyzes the transfer of an amino group between 2- oxoadipate (2-OA) and glutamate (Glu) to yield alpha-aminodipate (AAA). It can also transaminate glutamate, leucine, and aromatic amino acids. It also conbtributes in the biosynthesis of other amino acid

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=410, Percent_Identity=30, Blast_Score=181, Evalue=9e-46,
Organism=Homo sapiens, GI33469970, Length=410, Percent_Identity=30, Blast_Score=181, Evalue=9e-46,
Organism=Escherichia coli, GI1787710, Length=381, Percent_Identity=28.8713910761155, Blast_Score=157, Evalue=9e-40,
Organism=Escherichia coli, GI1790797, Length=336, Percent_Identity=28.5714285714286, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1788722, Length=345, Percent_Identity=25.7971014492754, Blast_Score=71, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321236, Length=485, Percent_Identity=24.5360824742268, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6321000, Length=264, Percent_Identity=28.4090909090909, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6321929, Length=489, Percent_Identity=24.1308793456033, Blast_Score=89, Evalue=8e-19,
Organism=Drosophila melanogaster, GI21356535, Length=392, Percent_Identity=26.7857142857143, Blast_Score=132, Evalue=5e-31,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.39 [H]

Molecular weight: Translated: 43448; Mature: 43448

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPSDLHPPHWQLSERARKLTSSAIREILKVTERPEVISFAGGLPAPATFPAERMRAAAD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHH
RVLRDAPAAALQYSATEGYLPLREWIAERYSVRVSQVLITTGSQQALDLLGKALIDPNSP
HHHHHCCHHHHEECCCCCCCHHHHHHHHHHHHEEEEEEEECCCHHHHHHHHHHHCCCCCC
ILVETPTYLGALQSFSLYEPRYVQVPTDEQGLLPEGLTPELTQGARLLYAQPNFQNPTGR
EEEECCHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCHHHCCCCEEEEECCCCCCCCCC
RLPVERRRALAAFAQTSPFPVLEDDPYGALNYQGEPLPTMLSMAPDHVVHLGTFSKVLAP
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCEEEHHHHHHHHCC
GLRIGYIIAPEELHFKLVQAKQATDLHTPTLTQRIAHEVIKDGFLDEHIPTIRELYSAQC
CCEEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
DAMLGALTRHMPAGVTWNRPEGGMFIWVNLPAQIDSMKLLAAAVDNHVAFVPGAPFFAEN
HHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEECCCCHHHCC
AQQNTLRLSFVTVPPEKIEEGVARLGKLLRERL
CCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNPSDLHPPHWQLSERARKLTSSAIREILKVTERPEVISFAGGLPAPATFPAERMRAAAD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHH
RVLRDAPAAALQYSATEGYLPLREWIAERYSVRVSQVLITTGSQQALDLLGKALIDPNSP
HHHHHCCHHHHEECCCCCCCHHHHHHHHHHHHEEEEEEEECCCHHHHHHHHHHHCCCCCC
ILVETPTYLGALQSFSLYEPRYVQVPTDEQGLLPEGLTPELTQGARLLYAQPNFQNPTGR
EEEECCHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCHHHCCCCEEEEECCCCCCCCCC
RLPVERRRALAAFAQTSPFPVLEDDPYGALNYQGEPLPTMLSMAPDHVVHLGTFSKVLAP
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCEEEHHHHHHHHCC
GLRIGYIIAPEELHFKLVQAKQATDLHTPTLTQRIAHEVIKDGFLDEHIPTIRELYSAQC
CCEEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
DAMLGALTRHMPAGVTWNRPEGGMFIWVNLPAQIDSMKLLAAAVDNHVAFVPGAPFFAEN
HHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEECCCCHHHCC
AQQNTLRLSFVTVPPEKIEEGVARLGKLLRERL
CCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA