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The map label for this gene is gluQ

Identifier: 116690336

GI number: 116690336

Start: 2573750

End: 2574646

Strand: Direct

Name: gluQ

Synonym: Bcen2424_2315

Alternate gene names: 116690336

Gene position: 2573750-2574646 (Clockwise)

Preceding gene: 116690335

Following gene: 116690341

Centisome position: 73.88

GC content: 71.57

Gene sequence:

>897_bases
ATGAACCCCGGCTATCGCGGCCGCTTCGCGCCTTCGCCCACCGGCCCGCTGCACTTCGGCTCGCTGGTCGGCGCGCTCGC
GAGCTGGCTCGACGCGCGCGCACACGGCGGCGTCTGGCTCGTGCGCATCGAGGATCTAGATGGCCCGCGCACGGTGCCCG
GTGCGGCCGACGACATCCTCGCGACGCTCGCGCATTTCGGCATGACACCCGACGAGCCGCCCGTCTGGCAGAGCACGCGC
GACGCGGCGTACACGGCCGCGCTCGAGCGGCTCGTCGCGGCGGGGCTCGTCTATCCGTGCGGCTGCACGCGCAAGGAGAT
CGCCGATTCACTGCGCGCCGCCCATGAACGCCACACGACGCTCGCGTATCCGGGCACCTGTCGCACCGGCCTGCACGGCA
AGCCCGCGCGCGCATGGCGGCTGCGCGTGCCGGACGGCTGCGACGCGGTCATCACTTTCGACGATCGCTGGCAGCACACG
CAATCGCAGAACCTCGCGACCGAAGTGGGCGATTTCGTGCTGAAACGCGCGGACGGCCAGTGGGCGTATCAGCTCGCGGT
CGTCGTCGACGATGCCGATGCCGGCATCACGCACGTCGTACGCGGCGCCGACCTGCTCGACTCGACCGCACGCCAGATCT
ACCTGCAGCGCTGCCTCGGCGTGCCGACGCCCGAGTACCTGCACGTGCCGGTCGTCGTCGATGCGAACGGCGAAAAGCTC
AGCAAGCAGACGGGCGCGACGGCGCTCGAACGCAACGATCCGCTGCCGGCGCTGCAGGCTGCGGCCGCGCATCTCGGCCT
GGCCAACGATGGCGATCTACCGGGCGGGACGCTCGACGCGTTCTACGCGGCCGCGACCGATGCGTGGGCGCGTCGCTTCG
GGCCGCGCGCCGGTTGA

Upstream 100 bases:

>100_bases
GAAGCGCAACAATCGCCGAGCTACGTGCCCGGCAAGTCGTGCCCCGCCTGCCCACAGGCCGCCAGCGCCGCGTAACGGCG
CATCGCACCGCGCACCGCCG

Downstream 100 bases:

>100_bases
GTCGCTTGCAGGACACCGGCCCGTGCCGACTACGCTCCGGCCTCCGCGAGCGGCGAATCCGCTCGCATGAAAGCATGACG
GAAGCCTGAGCGCCACGCCG

Product: glutamyl-Q tRNA(Asp) synthetase

Products: NA

Alternate protein names: Glu-Q-RSs

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MNPGYRGRFAPSPTGPLHFGSLVGALASWLDARAHGGVWLVRIEDLDGPRTVPGAADDILATLAHFGMTPDEPPVWQSTR
DAAYTAALERLVAAGLVYPCGCTRKEIADSLRAAHERHTTLAYPGTCRTGLHGKPARAWRLRVPDGCDAVITFDDRWQHT
QSQNLATEVGDFVLKRADGQWAYQLAVVVDDADAGITHVVRGADLLDSTARQIYLQRCLGVPTPEYLHVPVVVDANGEKL
SKQTGATALERNDPLPALQAAAAHLGLANDGDLPGGTLDAFYAAATDAWARRFGPRAG

Sequences:

>Translated_298_residues
MNPGYRGRFAPSPTGPLHFGSLVGALASWLDARAHGGVWLVRIEDLDGPRTVPGAADDILATLAHFGMTPDEPPVWQSTR
DAAYTAALERLVAAGLVYPCGCTRKEIADSLRAAHERHTTLAYPGTCRTGLHGKPARAWRLRVPDGCDAVITFDDRWQHT
QSQNLATEVGDFVLKRADGQWAYQLAVVVDDADAGITHVVRGADLLDSTARQIYLQRCLGVPTPEYLHVPVVVDANGEKL
SKQTGATALERNDPLPALQAAAAHLGLANDGDLPGGTLDAFYAAATDAWARRFGPRAG
>Mature_298_residues
MNPGYRGRFAPSPTGPLHFGSLVGALASWLDARAHGGVWLVRIEDLDGPRTVPGAADDILATLAHFGMTPDEPPVWQSTR
DAAYTAALERLVAAGLVYPCGCTRKEIADSLRAAHERHTTLAYPGTCRTGLHGKPARAWRLRVPDGCDAVITFDDRWQHT
QSQNLATEVGDFVLKRADGQWAYQLAVVVDDADAGITHVVRGADLLDSTARQIYLQRCLGVPTPEYLHVPVVVDANGEKL
SKQTGATALERNDPLPALQAAAAHLGLANDGDLPGGTLDAFYAAATDAWARRFGPRAG

Specific function: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble positi

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily

Homologues:

Organism=Homo sapiens, GI134288884, Length=290, Percent_Identity=35.8620689655172, Blast_Score=155, Evalue=5e-38,
Organism=Escherichia coli, GI226510925, Length=285, Percent_Identity=43.5087719298246, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI1788743, Length=246, Percent_Identity=35.3658536585366, Blast_Score=156, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI71993394, Length=299, Percent_Identity=31.1036789297659, Blast_Score=132, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6324540, Length=297, Percent_Identity=34.006734006734, Blast_Score=138, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24665321, Length=262, Percent_Identity=35.4961832061069, Blast_Score=135, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLUQ_BURCA (Q1BUU8)

Other databases:

- EMBL:   CP000378
- RefSeq:   YP_621580.1
- ProteinModelPortal:   Q1BUU8
- SMR:   Q1BUU8
- STRING:   Q1BUU8
- GeneID:   4091034
- GenomeReviews:   CP000378_GR
- KEGG:   bcn:Bcen_1703
- eggNOG:   COG0008
- HOGENOM:   HBG628189
- OMA:   IIKRSDG
- ProtClustDB:   PRK05710
- BioCyc:   BCEN331271:BCEN_1703-MONOMER
- GO:   GO:0005737
- GO:   GO:0006412
- HAMAP:   MF_01428
- InterPro:   IPR022380
- InterPro:   IPR000924
- InterPro:   IPR020058
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR10119
- PRINTS:   PR00987
- TIGRFAMs:   TIGR03838

Pfam domain/function: PF00749 tRNA-synt_1c

EC number: NA

Molecular weight: Translated: 31886; Mature: 31886

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 44-44 BINDING 183-183 BINDING 201-201 BINDING 242-242

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPGYRGRFAPSPTGPLHFGSLVGALASWLDARAHGGVWLVRIEDLDGPRTVPGAADDIL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHH
ATLAHFGMTPDEPPVWQSTRDAAYTAALERLVAAGLVYPCGCTRKEIADSLRAAHERHTT
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCE
LAYPGTCRTGLHGKPARAWRLRVPDGCDAVITFDDRWQHTQSQNLATEVGDFVLKRADGQ
EECCCCCCCCCCCCCCCEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCC
WAYQLAVVVDDADAGITHVVRGADLLDSTARQIYLQRCLGVPTPEYLHVPVVVDANGEKL
EEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCHHH
SKQTGATALERNDPLPALQAAAAHLGLANDGDLPGGTLDAFYAAATDAWARRFGPRAG
HHHHCCCHHHCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNPGYRGRFAPSPTGPLHFGSLVGALASWLDARAHGGVWLVRIEDLDGPRTVPGAADDIL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHH
ATLAHFGMTPDEPPVWQSTRDAAYTAALERLVAAGLVYPCGCTRKEIADSLRAAHERHTT
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCE
LAYPGTCRTGLHGKPARAWRLRVPDGCDAVITFDDRWQHTQSQNLATEVGDFVLKRADGQ
EECCCCCCCCCCCCCCCEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCC
WAYQLAVVVDDADAGITHVVRGADLLDSTARQIYLQRCLGVPTPEYLHVPVVVDANGEKL
EEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCHHH
SKQTGATALERNDPLPALQAAAAHLGLANDGDLPGGTLDAFYAAATDAWARRFGPRAG
HHHHCCCHHHCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA