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The map label for this gene is mas [H]

Identifier: 116690273

GI number: 116690273

Start: 2505851

End: 2506870

Strand: Reverse

Name: mas [H]

Synonym: Bcen2424_2252

Alternate gene names: 116690273

Gene position: 2506870-2505851 (Counterclockwise)

Preceding gene: 116690274

Following gene: 116690272

Centisome position: 71.96

GC content: 69.31

Gene sequence:

>1020_bases
ATGAAAGCCATCGAAATCACCGAATTCGGCGCCCCCGACGTGCTGAAGCTCGCGGAGCGTCCGCGCCCCGAACCGAAGCG
CGGCGAGGTGCTGATCAAGGTGGCGGCTTCCGGCGTGAACCGGCCCGACGTGTTCCAGCGCAAGGGTGCCTATGCGCCGC
CGCCGGGTGCGTCGGATCTGCCGGGCCTCGAGGTCGCGGGCGAGATCGTCGGTGGCGATTTGTCCGATGCGGCCCTGAAC
CCGTTCGGGCTGAAACTGGGCGATCGCGTGTGCGCGCTGCTCGCGGGCGGCGGCTATGCCGAATATGCGGTCGCGCCGCT
GCCGCAGTGCCTGCCGGTGCCGGATGGCCTCACCGATATCGAGGCCGCCTCGCTGCCCGAAACGTTTTTCACCGTGTGGA
GCAACGTGTTCGACCGTGCGCAGCTCGGCGCGGGCGAAGGCGGCGAGCAGGAGACCCTGCTCGTGCAGGGCGGCTCGAGC
GGCATCGGCGTGACGGCGATCCAGATCGCGCATGCGCTCGGCTTTCGGGTGTTCGCGACGGCCGGTACCGCCGACAAGTG
CCGTGCGTGCGAGGCGCTCGGCGCCGAGCGCGCGATCAACTACAAGACCGAAGACTTCGTCGAAGTCGTGAAGTCGCTGA
CGCACGATCGCGGTGTCGACGTGATCCTCGACATGGTGGCGGGCTCGTACGTGCCGCGCGAGCTGTCCGCGCTCGCGGAC
GGCGGCCGTCTCGTGCTGATCGCGCTGCTCGGCGGCGCGAAGGCCGAGGTCAACCTGAGCGAGATCCTGCGCCGCCGGCT
GACCGTGACCGGCTCGACGCTGCGTCCGCGCCCGGTCGAATTCAAGGCCCGTATCGCCGCGCAGCTGAAGGCGCGCGTGT
GGCCGCTGCTCGCCGACGGCCGCATCAAGCCGGTGATCTATCGCGTGTTGCCCGCCGCGGACGCCGCCCAGGCGCATGCG
CTGATGGAAAGCAGCGAGCATACCGGCAAGATCGTGCTCGATTGGGGAACGAACGCCTGA

Upstream 100 bases:

>100_bases
TTTTCTGTAGCATCGTTGTGCGGCGCAGCAGCGCCGGCGAGGCGCCCGCGCCGTGCGCACGGGCGTGCCATCCGATTCCG
ATCCTGGAGCGACTCTCACC

Downstream 100 bases:

>100_bases
CGGCCCGTGCGGCGGGCTTGACATGCGCGGTTTGACCGGTTCAAGCCGCGCGCAGTAAAATCGCGGGTTTGCTTCGCCAG
ATCCAACCTGACGGCCGGGT

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MKAIEITEFGAPDVLKLAERPRPEPKRGEVLIKVAASGVNRPDVFQRKGAYAPPPGASDLPGLEVAGEIVGGDLSDAALN
PFGLKLGDRVCALLAGGGYAEYAVAPLPQCLPVPDGLTDIEAASLPETFFTVWSNVFDRAQLGAGEGGEQETLLVQGGSS
GIGVTAIQIAHALGFRVFATAGTADKCRACEALGAERAINYKTEDFVEVVKSLTHDRGVDVILDMVAGSYVPRELSALAD
GGRLVLIALLGGAKAEVNLSEILRRRLTVTGSTLRPRPVEFKARIAAQLKARVWPLLADGRIKPVIYRVLPAADAAQAHA
LMESSEHTGKIVLDWGTNA

Sequences:

>Translated_339_residues
MKAIEITEFGAPDVLKLAERPRPEPKRGEVLIKVAASGVNRPDVFQRKGAYAPPPGASDLPGLEVAGEIVGGDLSDAALN
PFGLKLGDRVCALLAGGGYAEYAVAPLPQCLPVPDGLTDIEAASLPETFFTVWSNVFDRAQLGAGEGGEQETLLVQGGSS
GIGVTAIQIAHALGFRVFATAGTADKCRACEALGAERAINYKTEDFVEVVKSLTHDRGVDVILDMVAGSYVPRELSALAD
GGRLVLIALLGGAKAEVNLSEILRRRLTVTGSTLRPRPVEFKARIAAQLKARVWPLLADGRIKPVIYRVLPAADAAQAHA
LMESSEHTGKIVLDWGTNA
>Mature_339_residues
MKAIEITEFGAPDVLKLAERPRPEPKRGEVLIKVAASGVNRPDVFQRKGAYAPPPGASDLPGLEVAGEIVGGDLSDAALN
PFGLKLGDRVCALLAGGGYAEYAVAPLPQCLPVPDGLTDIEAASLPETFFTVWSNVFDRAQLGAGEGGEQETLLVQGGSS
GIGVTAIQIAHALGFRVFATAGTADKCRACEALGAERAINYKTEDFVEVVKSLTHDRGVDVILDMVAGSYVPRELSALAD
GGRLVLIALLGGAKAEVNLSEILRRRLTVTGSTLRPRPVEFKARIAAQLKARVWPLLADGRIKPVIYRVLPAADAAQAHA
LMESSEHTGKIVLDWGTNA

Specific function: Catalyzes the elongation of N-fatty acyl-CoA with methylamalonyl-CoA (not malonyl-CoA) as the elongating agent to form mycocerosyl lipids [H]

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=343, Percent_Identity=37.0262390670554, Blast_Score=212, Evalue=3e-55,
Organism=Homo sapiens, GI22538444, Length=343, Percent_Identity=37.0262390670554, Blast_Score=212, Evalue=3e-55,
Organism=Homo sapiens, GI194239674, Length=337, Percent_Identity=33.5311572700297, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI13236495, Length=337, Percent_Identity=33.5311572700297, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI194239676, Length=337, Percent_Identity=30.8605341246291, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI18379349, Length=352, Percent_Identity=28.6931818181818, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI24308257, Length=355, Percent_Identity=26.7605633802817, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI197927207, Length=184, Percent_Identity=30.9782608695652, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI28557745, Length=285, Percent_Identity=29.1228070175439, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI41872631, Length=321, Percent_Identity=27.7258566978193, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI47519420, Length=359, Percent_Identity=27.0194986072423, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1790485, Length=340, Percent_Identity=29.7058823529412, Blast_Score=100, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17507255, Length=272, Percent_Identity=31.6176470588235, Blast_Score=109, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6319520, Length=344, Percent_Identity=25.5813953488372, Blast_Score=86, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6323961, Length=349, Percent_Identity=26.3610315186246, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324486, Length=349, Percent_Identity=26.0744985673352, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI221330659, Length=252, Percent_Identity=25.7936507936508, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19920632, Length=252, Percent_Identity=25.7936507936508, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24581345, Length=252, Percent_Identity=25, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR009081
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR000794
- InterPro:   IPR011032
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016036
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020842
- InterPro:   IPR020801
- InterPro:   IPR020841
- InterPro:   IPR020807
- InterPro:   IPR020843
- InterPro:   IPR013968
- InterPro:   IPR006162
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF08240 ADH_N; PF00107 ADH_zinc_N; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF08659 KR; PF00550 PP-binding [H]

EC number: =2.3.1.111 [H]

Molecular weight: Translated: 35689; Mature: 35689

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIEITEFGAPDVLKLAERPRPEPKRGEVLIKVAASGVNRPDVFQRKGAYAPPPGASDL
CCCEEECCCCCCHHHHHHHCCCCCCCCCCEEEEEECCCCCCCHHHHHCCCCCCCCCCCCC
PGLEVAGEIVGGDLSDAALNPFGLKLGDRVCALLAGGGYAEYAVAPLPQCLPVPDGLTDI
CCHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCC
EAASLPETFFTVWSNVFDRAQLGAGEGGEQETLLVQGGSSGIGVTAIQIAHALGFRVFAT
CHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCEEEEE
AGTADKCRACEALGAERAINYKTEDFVEVVKSLTHDRGVDVILDMVAGSYVPRELSALAD
CCCHHHHHHHHHHCHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHCC
GGRLVLIALLGGAKAEVNLSEILRRRLTVTGSTLRPRPVEFKARIAAQLKARVWPLLADG
CCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCEEECCC
RIKPVIYRVLPAADAAQAHALMESSEHTGKIVLDWGTNA
CCCHHHHEECCCCCHHHHHHHHHCCCCCCEEEEECCCCC
>Mature Secondary Structure
MKAIEITEFGAPDVLKLAERPRPEPKRGEVLIKVAASGVNRPDVFQRKGAYAPPPGASDL
CCCEEECCCCCCHHHHHHHCCCCCCCCCCEEEEEECCCCCCCHHHHHCCCCCCCCCCCCC
PGLEVAGEIVGGDLSDAALNPFGLKLGDRVCALLAGGGYAEYAVAPLPQCLPVPDGLTDI
CCHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCC
EAASLPETFFTVWSNVFDRAQLGAGEGGEQETLLVQGGSSGIGVTAIQIAHALGFRVFAT
CHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCEEEEE
AGTADKCRACEALGAERAINYKTEDFVEVVKSLTHDRGVDVILDMVAGSYVPRELSALAD
CCCHHHHHHHHHHCHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHCC
GGRLVLIALLGGAKAEVNLSEILRRRLTVTGSTLRPRPVEFKARIAAQLKARVWPLLADG
CCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCEEECCC
RIKPVIYRVLPAADAAQAHALMESSEHTGKIVLDWGTNA
CCCHHHHEECCCCCHHHHHHHHHCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1527058; 12788972 [H]