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The map label for this gene is nuoC [H]

Identifier: 116690268

GI number: 116690268

Start: 2502631

End: 2503233

Strand: Reverse

Name: nuoC [H]

Synonym: Bcen2424_2247

Alternate gene names: 116690268

Gene position: 2503233-2502631 (Counterclockwise)

Preceding gene: 116690269

Following gene: 116690267

Centisome position: 71.85

GC content: 63.85

Gene sequence:

>603_bases
ATGGCAAGCAAAATCGAGACCCTGAAGGCAAACCTCGAAGCCGCGCTCGGCGCGCGCGTGGTGAGCCTCACCGAAGCGAT
CGGTGAACTGACGCTCGTCGTGAAGGCGAGCGATTACCTCGAAGTCGCAAAGACGCTGCGCGATGATCCGAAGCTCCGTT
TCGAGCAACTGATCGACCTCTGCGGCGTCGACTACCAGACCTTCGGCGACGGCGCCTACGACGGCCCGCGCTTCGCGGCC
GTGTCGCACCTGCTGTCGGTCACGAACAACTGGCGCCTGCGCCTGCGCGCATTCGCGCCGGACGACGATCTGCCGATCGT
GGCGTCGCTGGTCGACATCTGGACCTCGGCGAACTGGTACGAGCGCGAAGCGTTCGACCTGTACGGCATCGTGTTCGAAG
GCCACCCCGACCTGCGCCGCATCCTCACCGACTACGGCTTCATCGGTCACCCGTTCCGCAAGGACTTCCCGGTGTCGGGC
TACGTCGAAATGCGTTACGACCCGGAAGAGAAGCGGGTCGTGTACCAGCCGGTGACGATCGAGCCGCGCGAAATCACGCC
GCGCGTGATCCGCGAGGATCGCTATGGCGGTCTGAAACATTAA

Upstream 100 bases:

>100_bases
CACGGCCGAGGCGCTGGTCTACGGCGTGATCCAGCTTCAGGCGAAGATCCGCCGCACCAATACCATCGCCCGTCAATAAA
GCCCCGAGCGTCCCCTCAAT

Downstream 100 bases:

>100_bases
GGGGGCGTCATGGCAGAAATCAAGAACTACACGCTCAACTTCGGCCCGCAGCACCCGGCAGCGCACGGCGTGCTGCGCCT
CGTGCTCGAGCTCGACGGCG

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MASKIETLKANLEAALGARVVSLTEAIGELTLVVKASDYLEVAKTLRDDPKLRFEQLIDLCGVDYQTFGDGAYDGPRFAA
VSHLLSVTNNWRLRLRAFAPDDDLPIVASLVDIWTSANWYEREAFDLYGIVFEGHPDLRRILTDYGFIGHPFRKDFPVSG
YVEMRYDPEEKRVVYQPVTIEPREITPRVIREDRYGGLKH

Sequences:

>Translated_200_residues
MASKIETLKANLEAALGARVVSLTEAIGELTLVVKASDYLEVAKTLRDDPKLRFEQLIDLCGVDYQTFGDGAYDGPRFAA
VSHLLSVTNNWRLRLRAFAPDDDLPIVASLVDIWTSANWYEREAFDLYGIVFEGHPDLRRILTDYGFIGHPFRKDFPVSG
YVEMRYDPEEKRVVYQPVTIEPREITPRVIREDRYGGLKH
>Mature_199_residues
ASKIETLKANLEAALGARVVSLTEAIGELTLVVKASDYLEVAKTLRDDPKLRFEQLIDLCGVDYQTFGDGAYDGPRFAAV
SHLLSVTNNWRLRLRAFAPDDDLPIVASLVDIWTSANWYEREAFDLYGIVFEGHPDLRRILTDYGFIGHPFRKDFPVSGY
VEMRYDPEEKRVVYQPVTIEPREITPRVIREDRYGGLKH

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=155, Percent_Identity=47.0967741935484, Blast_Score=142, Evalue=2e-34,
Organism=Escherichia coli, GI145693162, Length=126, Percent_Identity=38.8888888888889, Blast_Score=85, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71990788, Length=149, Percent_Identity=44.2953020134228, Blast_Score=130, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI32563621, Length=149, Percent_Identity=44.2953020134228, Blast_Score=130, Evalue=6e-31,
Organism=Drosophila melanogaster, GI24656494, Length=160, Percent_Identity=45, Blast_Score=136, Evalue=8e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 22823; Mature: 22692

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASKIETLKANLEAALGARVVSLTEAIGELTLVVKASDYLEVAKTLRDDPKLRFEQLIDL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECHHHHHHHHHHCCCCCHHHHHHHHH
CGVDYQTFGDGAYDGPRFAAVSHLLSVTNNWRLRLRAFAPDDDLPIVASLVDIWTSANWY
HCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCC
EREAFDLYGIVFEGHPDLRRILTDYGFIGHPFRKDFPVSGYVEMRYDPEEKRVVYQPVTI
CCCCEEEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCEEEECCCCC
EPREITPRVIREDRYGGLKH
CCHHCCHHHHHHCCCCCCCC
>Mature Secondary Structure 
ASKIETLKANLEAALGARVVSLTEAIGELTLVVKASDYLEVAKTLRDDPKLRFEQLIDL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECHHHHHHHHHHCCCCCHHHHHHHHH
CGVDYQTFGDGAYDGPRFAAVSHLLSVTNNWRLRLRAFAPDDDLPIVASLVDIWTSANWY
HCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCC
EREAFDLYGIVFEGHPDLRRILTDYGFIGHPFRKDFPVSGYVEMRYDPEEKRVVYQPVTI
CCCCEEEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCEEEECCCCC
EPREITPRVIREDRYGGLKH
CCHHCCHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA