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The map label for this gene is nuoD [H]

Identifier: 116690267

GI number: 116690267

Start: 2501368

End: 2502621

Strand: Reverse

Name: nuoD [H]

Synonym: Bcen2424_2246

Alternate gene names: 116690267

Gene position: 2502621-2501368 (Counterclockwise)

Preceding gene: 116690268

Following gene: 116690266

Centisome position: 71.83

GC content: 61.72

Gene sequence:

>1254_bases
ATGGCAGAAATCAAGAACTACACGCTCAACTTCGGCCCGCAGCACCCGGCAGCGCACGGCGTGCTGCGCCTCGTGCTCGA
GCTCGACGGCGAAGTCATCCAGCGTGCCGATCCGCACATCGGCCTGCTGCACCGCGCGACGGAAAAGCTCGCGGAATCCA
AGACCTTCATCCAGTCCGTGCCGTACATGGACCGTCTCGACTACGTGTCGATGATGGTCAACGAGCACGGCTACGTACTC
GCGATCGAAAAGCTGCTCGGCATCGAAGTGCCGGAGCGCGCGCAGTACATCCGCGTGCTGTTCGACGAAATCACGCGCGT
GCTGAACCACCTGATGTGGATTGGCGCGCACGCACTCGACGTCGGCGCGATGGCCGTGTTCCTGTACGCCTTCCGCGAAC
GCGAAGACCTGATGGACGTGTACGAAGCGGTGTCCGGCGCCCGGATGCACGCGGCCTACTATCGTCCGGGCGGCGTCTAT
CGCGATCTGCCTGACGCAATGCCGCAATACAAGGCGTCGAAGATTCGCAACGAGAAGGCGCTCGCGAAGATGAACGAAGC
GCGCAGCGGTTCGGTGCTCGACTTCATCGACGATTTCTTCACGCGCTTCCCGAAGTGCGTCGACGAATACGAAACGCTGC
TGACCGACAACCGGATCTGGAAACAGCGTCTGGTCGGGATCGGCGTGGTGAGCCCGGAACGTGCGCTGCAGATGGGCCTG
ACCGGCCCGATGCTGCGCGGCTCGGGCATCGCGTGGGACCTGCGCAAGAAGCAGCCCTACGAAGTGTACGATCGGATGGA
TTTCGACGTGCCGGTCGGCGTGAACGGCGATTGCTACGACCGCTATCTGGTGCGCGTCGAAGAAATGCGCCAGTCGATCC
GCATCGCGAAACAGTGTATTGAGTGGCTCCGCAAGAATCCGGGCCCGGTGATGACGGACAATCACAAGGTTGCCCCGCCG
TCGCGCGTCGGCATGAAGACCAACATGGAAGACTTGATTCACCACTTCAAGCTCTTCACCGAAGGTTTCCATGTGCCGGA
AGGCGAAGCGTACGCGGCGGTCGAGCATCCGAAGGGCGAGTTCGGCATCTATCTCGTGTCGGATGGCGCCAACAAGCCGT
ATCGCCTCAAGATTCGCGCGCCGGGTTTCGCGCACCTGGCGTCGCTCGACGAAATGGCGCGCGGTCACATGATTGCCGAC
GCCGTCACGATCATCGGTACGCAGGACATCGTGTTCGGCGAAATCGATCGCTAA

Upstream 100 bases:

>100_bases
GCGGGTCGTGTACCAGCCGGTGACGATCGAGCCGCGCGAAATCACGCCGCGCGTGATCCGCGAGGATCGCTATGGCGGTC
TGAAACATTAAGGGGGCGTC

Downstream 100 bases:

>100_bases
TGGTTGCGCCGCCCGCGAGCGCGGGCGGCGAGCAGTCAGTCACACGCGAAGTCACATGCGGCATGCGCCGAATCGGCGCG
GCTTCGCAAGCTGTCAACAG

Product: NADH dehydrogenase subunit D

Products: NA

Alternate protein names: NADH dehydrogenase I subunit D; NDH-1 subunit D [H]

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MAEIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAESKTFIQSVPYMDRLDYVSMMVNEHGYVL
AIEKLLGIEVPERAQYIRVLFDEITRVLNHLMWIGAHALDVGAMAVFLYAFREREDLMDVYEAVSGARMHAAYYRPGGVY
RDLPDAMPQYKASKIRNEKALAKMNEARSGSVLDFIDDFFTRFPKCVDEYETLLTDNRIWKQRLVGIGVVSPERALQMGL
TGPMLRGSGIAWDLRKKQPYEVYDRMDFDVPVGVNGDCYDRYLVRVEEMRQSIRIAKQCIEWLRKNPGPVMTDNHKVAPP
SRVGMKTNMEDLIHHFKLFTEGFHVPEGEAYAAVEHPKGEFGIYLVSDGANKPYRLKIRAPGFAHLASLDEMARGHMIAD
AVTIIGTQDIVFGEIDR

Sequences:

>Translated_417_residues
MAEIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAESKTFIQSVPYMDRLDYVSMMVNEHGYVL
AIEKLLGIEVPERAQYIRVLFDEITRVLNHLMWIGAHALDVGAMAVFLYAFREREDLMDVYEAVSGARMHAAYYRPGGVY
RDLPDAMPQYKASKIRNEKALAKMNEARSGSVLDFIDDFFTRFPKCVDEYETLLTDNRIWKQRLVGIGVVSPERALQMGL
TGPMLRGSGIAWDLRKKQPYEVYDRMDFDVPVGVNGDCYDRYLVRVEEMRQSIRIAKQCIEWLRKNPGPVMTDNHKVAPP
SRVGMKTNMEDLIHHFKLFTEGFHVPEGEAYAAVEHPKGEFGIYLVSDGANKPYRLKIRAPGFAHLASLDEMARGHMIAD
AVTIIGTQDIVFGEIDR
>Mature_416_residues
AEIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAESKTFIQSVPYMDRLDYVSMMVNEHGYVLA
IEKLLGIEVPERAQYIRVLFDEITRVLNHLMWIGAHALDVGAMAVFLYAFREREDLMDVYEAVSGARMHAAYYRPGGVYR
DLPDAMPQYKASKIRNEKALAKMNEARSGSVLDFIDDFFTRFPKCVDEYETLLTDNRIWKQRLVGIGVVSPERALQMGLT
GPMLRGSGIAWDLRKKQPYEVYDRMDFDVPVGVNGDCYDRYLVRVEEMRQSIRIAKQCIEWLRKNPGPVMTDNHKVAPPS
RVGMKTNMEDLIHHFKLFTEGFHVPEGEAYAAVEHPKGEFGIYLVSDGANKPYRLKIRAPGFAHLASLDEMARGHMIADA
VTIIGTQDIVFGEIDR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0649

COG function: function code C; NADH:ubiquinone oxidoreductase 49 kD subunit 7

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 49 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758786, Length=414, Percent_Identity=61.5942028985507, Blast_Score=520, Evalue=1e-148,
Organism=Homo sapiens, GI260898743, Length=408, Percent_Identity=60.7843137254902, Blast_Score=504, Evalue=1e-143,
Organism=Escherichia coli, GI145693162, Length=410, Percent_Identity=38.2926829268293, Blast_Score=300, Evalue=1e-82,
Organism=Escherichia coli, GI1789076, Length=422, Percent_Identity=28.1990521327014, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI1788832, Length=408, Percent_Identity=27.4509803921569, Blast_Score=118, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17555284, Length=415, Percent_Identity=59.2771084337349, Blast_Score=492, Evalue=1e-139,
Organism=Caenorhabditis elegans, GI17568379, Length=415, Percent_Identity=58.0722891566265, Blast_Score=489, Evalue=1e-138,
Organism=Drosophila melanogaster, GI24638644, Length=415, Percent_Identity=60.7228915662651, Blast_Score=526, Evalue=1e-149,
Organism=Drosophila melanogaster, GI221459469, Length=412, Percent_Identity=55.5825242718447, Blast_Score=471, Evalue=1e-133,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010219
- InterPro:   IPR001135
- InterPro:   IPR014029
- InterPro:   IPR022885 [H]

Pfam domain/function: PF00346 Complex1_49kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 47444; Mature: 47313

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS00535 COMPLEX1_49K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAESKTFIQSV
CCCCCCCEEECCCCCCHHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
PYMDRLDYVSMMVNEHGYVLAIEKLLGIEVPERAQYIRVLFDEITRVLNHLMWIGAHALD
CCHHHHHHHHHHHCCCCCEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGAMAVFLYAFREREDLMDVYEAVSGARMHAAYYRPGGVYRDLPDAMPQYKASKIRNEKA
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
LAKMNEARSGSVLDFIDDFFTRFPKCVDEYETLLTDNRIWKQRLVGIGVVSPERALQMGL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHCC
TGPMLRGSGIAWDLRKKQPYEVYDRMDFDVPVGVNGDCYDRYLVRVEEMRQSIRIAKQCI
CCCCCCCCCCEEECCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EWLRKNPGPVMTDNHKVAPPSRVGMKTNMEDLIHHFKLFTEGFHVPEGEAYAAVEHPKGE
HHHHCCCCCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCC
FGIYLVSDGANKPYRLKIRAPGFAHLASLDEMARGHMIADAVTIIGTQDIVFGEIDR
EEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHCCCCCEEECCCCC
>Mature Secondary Structure 
AEIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAESKTFIQSV
CCCCCCEEECCCCCCHHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
PYMDRLDYVSMMVNEHGYVLAIEKLLGIEVPERAQYIRVLFDEITRVLNHLMWIGAHALD
CCHHHHHHHHHHHCCCCCEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGAMAVFLYAFREREDLMDVYEAVSGARMHAAYYRPGGVYRDLPDAMPQYKASKIRNEKA
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
LAKMNEARSGSVLDFIDDFFTRFPKCVDEYETLLTDNRIWKQRLVGIGVVSPERALQMGL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHCC
TGPMLRGSGIAWDLRKKQPYEVYDRMDFDVPVGVNGDCYDRYLVRVEEMRQSIRIAKQCI
CCCCCCCCCCEEECCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EWLRKNPGPVMTDNHKVAPPSRVGMKTNMEDLIHHFKLFTEGFHVPEGEAYAAVEHPKGE
HHHHCCCCCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCC
FGIYLVSDGANKPYRLKIRAPGFAHLASLDEMARGHMIADAVTIIGTQDIVFGEIDR
EEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA