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The map label for this gene is yghZ [H]

Identifier: 116690234

GI number: 116690234

Start: 2464742

End: 2465713

Strand: Direct

Name: yghZ [H]

Synonym: Bcen2424_2213

Alternate gene names: 116690234

Gene position: 2464742-2465713 (Clockwise)

Preceding gene: 116690232

Following gene: 116690235

Centisome position: 70.75

GC content: 63.89

Gene sequence:

>972_bases
ATGCACTATCGACGGCTAGGCCGCTCCGGCCTGCAGATCAGCGAGCTTTCACTCGGTTCGTGGGTGACGTACGGCAACCA
GGTCGACCAGCGGGTCGCGCGCGAATGCCTCGCCGCGGCACGTGATGCAGGCGTCAATTTCTTCGACAACGCCGAGGTCT
ACGCCGGCGGCAAATCCGAGGAAATCATGGGCCATGCGCTTAAGTCGCTCGACTGGCCGCGCGTCAGTTATATCGTGTCC
ACGAAGTTCTTCTGGGGGCTCGCAGAAGCCCCGAACCAGTATCACACGCTGAACCGGAAATACCTGCTGAACGCAATCGA
CGGCTCGCTGCGCCGGCTACAGCTCGACTATGTCGACCTCGCCTATTGCCATCGCCCCGATCCGCATACGCCGATCGAGG
AAACCGTCTGGGCGATGAGCGACATGATCGTGCGCGGCAAGGCGCTGTACTGGGGCACGTCGGAATGGAGCGCCGACGAA
ATCCGCGCGGCATGCGAGATTGCCGAGCGGCATCATCTCCACAAGCCGGTCGTCGAACAACCGCAGTACAACCTGTTTCA
CCGCACCCGGGTCGAACAGGAATATGCGCGGCTCTACGACGATTACGGTCTCGGGCTCACGACCTGGAGCCCGTTGGCGT
CGGGCCTGCTCACCGGCAAGTACCGCAACGGCGTGCCGGCCGGCAGCCGCGCGCAGTTGCAAGGCTACGACTGGATGCGC
GAACGCCTGACCGATCGGGCCGCCAACGACATCGTCGAACGGCTCGGCGAAATTGCGGCCGAATTCGGCTGCAGCACCGG
CCAGTTGGCAATCGCGTGGGTGCTCGCGAACCCGCGCGTGAGTTCGGTCATCACGGGTGCATCGCGGGTCGACCAGATCG
GCGACAACATGCGCGCGCTCGAGGTTGCCGCGAAGCTGACGCCGGACGTGAAGCAGCGCATCGAGGCGGTGGTCGGCGAT
GCATACGAGTAA

Upstream 100 bases:

>100_bases
ATCGCATCAGCGTGCCAGCCGTCATTGTGCACGATCGGCCCCGCCGTTCGTGCACAAAACGTCTAAGCTTAAGGTCGGTT
CCGTTCAGCAGGAGAGTCTC

Downstream 100 bases:

>100_bases
GGCGACTCACGGCCACTCGCGTACAATACGCGGCCGCATCGGCGCCCGGCCTGACGGCCGCGCACGATCGACCGTTTTCA
TCGATTCACCTTTCGTTTCA

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MHYRRLGRSGLQISELSLGSWVTYGNQVDQRVARECLAAARDAGVNFFDNAEVYAGGKSEEIMGHALKSLDWPRVSYIVS
TKFFWGLAEAPNQYHTLNRKYLLNAIDGSLRRLQLDYVDLAYCHRPDPHTPIEETVWAMSDMIVRGKALYWGTSEWSADE
IRAACEIAERHHLHKPVVEQPQYNLFHRTRVEQEYARLYDDYGLGLTTWSPLASGLLTGKYRNGVPAGSRAQLQGYDWMR
ERLTDRAANDIVERLGEIAAEFGCSTGQLAIAWVLANPRVSSVITGASRVDQIGDNMRALEVAAKLTPDVKQRIEAVVGD
AYE

Sequences:

>Translated_323_residues
MHYRRLGRSGLQISELSLGSWVTYGNQVDQRVARECLAAARDAGVNFFDNAEVYAGGKSEEIMGHALKSLDWPRVSYIVS
TKFFWGLAEAPNQYHTLNRKYLLNAIDGSLRRLQLDYVDLAYCHRPDPHTPIEETVWAMSDMIVRGKALYWGTSEWSADE
IRAACEIAERHHLHKPVVEQPQYNLFHRTRVEQEYARLYDDYGLGLTTWSPLASGLLTGKYRNGVPAGSRAQLQGYDWMR
ERLTDRAANDIVERLGEIAAEFGCSTGQLAIAWVLANPRVSSVITGASRVDQIGDNMRALEVAAKLTPDVKQRIEAVVGD
AYE
>Mature_323_residues
MHYRRLGRSGLQISELSLGSWVTYGNQVDQRVARECLAAARDAGVNFFDNAEVYAGGKSEEIMGHALKSLDWPRVSYIVS
TKFFWGLAEAPNQYHTLNRKYLLNAIDGSLRRLQLDYVDLAYCHRPDPHTPIEETVWAMSDMIVRGKALYWGTSEWSADE
IRAACEIAERHHLHKPVVEQPQYNLFHRTRVEQEYARLYDDYGLGLTTWSPLASGLLTGKYRNGVPAGSRAQLQGYDWMR
ERLTDRAANDIVERLGEIAAEFGCSTGQLAIAWVLANPRVSSVITGASRVDQIGDNMRALEVAAKLTPDVKQRIEAVVGD
AYE

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI27436969, Length=323, Percent_Identity=43.9628482972136, Blast_Score=300, Evalue=1e-81,
Organism=Homo sapiens, GI4504825, Length=321, Percent_Identity=43.9252336448598, Blast_Score=298, Evalue=3e-81,
Organism=Homo sapiens, GI27436964, Length=321, Percent_Identity=45.1713395638629, Blast_Score=298, Evalue=4e-81,
Organism=Homo sapiens, GI27436962, Length=321, Percent_Identity=45.1713395638629, Blast_Score=296, Evalue=1e-80,
Organism=Homo sapiens, GI27436966, Length=321, Percent_Identity=44.8598130841121, Blast_Score=295, Evalue=3e-80,
Organism=Homo sapiens, GI27436971, Length=323, Percent_Identity=43.9628482972136, Blast_Score=284, Evalue=9e-77,
Organism=Homo sapiens, GI41152114, Length=295, Percent_Identity=29.4915254237288, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI223718702, Length=291, Percent_Identity=26.8041237113402, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI41327764, Length=270, Percent_Identity=29.2592592592593, Blast_Score=82, Evalue=6e-16,
Organism=Escherichia coli, GI1789375, Length=318, Percent_Identity=35.8490566037736, Blast_Score=178, Evalue=5e-46,
Organism=Escherichia coli, GI87081735, Length=315, Percent_Identity=34.9206349206349, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1788070, Length=320, Percent_Identity=29.375, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1789199, Length=348, Percent_Identity=30.7471264367816, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1788081, Length=303, Percent_Identity=25.4125412541254, Blast_Score=72, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6325169, Length=325, Percent_Identity=25.8461538461538, Blast_Score=108, Evalue=8e-25,
Organism=Saccharomyces cerevisiae, GI6323998, Length=330, Percent_Identity=26.969696969697, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6319958, Length=304, Percent_Identity=26.9736842105263, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6319951, Length=335, Percent_Identity=26.2686567164179, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6322615, Length=222, Percent_Identity=26.5765765765766, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24640980, Length=340, Percent_Identity=31.1764705882353, Blast_Score=185, Evalue=3e-47,
Organism=Drosophila melanogaster, GI45549126, Length=340, Percent_Identity=31.1764705882353, Blast_Score=185, Evalue=4e-47,
Organism=Drosophila melanogaster, GI24646155, Length=313, Percent_Identity=28.1150159744409, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24646159, Length=226, Percent_Identity=28.7610619469027, Blast_Score=85, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR005399
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 36365; Mature: 36365

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYRRLGRSGLQISELSLGSWVTYGNQVDQRVARECLAAARDAGVNFFDNAEVYAGGKSE
CCHHHHCCCCCEEEEECCCHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHH
EIMGHALKSLDWPRVSYIVSTKFFWGLAEAPNQYHTLNRKYLLNAIDGSLRRLQLDYVDL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHCCHHHHEEHHHHHH
AYCHRPDPHTPIEETVWAMSDMIVRGKALYWGTSEWSADEIRAACEIAERHHLHKPVVEQ
HHHCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHCC
PQYNLFHRTRVEQEYARLYDDYGLGLTTWSPLASGLLTGKYRNGVPAGSRAQLQGYDWMR
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
ERLTDRAANDIVERLGEIAAEFGCSTGQLAIAWVLANPRVSSVITGASRVDQIGDNMRAL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCHHHH
EVAAKLTPDVKQRIEAVVGDAYE
HHHHHCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MHYRRLGRSGLQISELSLGSWVTYGNQVDQRVARECLAAARDAGVNFFDNAEVYAGGKSE
CCHHHHCCCCCEEEEECCCHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHH
EIMGHALKSLDWPRVSYIVSTKFFWGLAEAPNQYHTLNRKYLLNAIDGSLRRLQLDYVDL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHCCHHHHEEHHHHHH
AYCHRPDPHTPIEETVWAMSDMIVRGKALYWGTSEWSADEIRAACEIAERHHLHKPVVEQ
HHHCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHCC
PQYNLFHRTRVEQEYARLYDDYGLGLTTWSPLASGLLTGKYRNGVPAGSRAQLQGYDWMR
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
ERLTDRAANDIVERLGEIAAEFGCSTGQLAIAWVLANPRVSSVITGASRVDQIGDNMRAL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCHHHH
EVAAKLTPDVKQRIEAVVGDAYE
HHHHHCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]