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The map label for this gene is aspC [H]

Identifier: 116690232

GI number: 116690232

Start: 2462466

End: 2463665

Strand: Direct

Name: aspC [H]

Synonym: Bcen2424_2211

Alternate gene names: 116690232

Gene position: 2462466-2463665 (Clockwise)

Preceding gene: 116690226

Following gene: 116690234

Centisome position: 70.68

GC content: 66.25

Gene sequence:

>1200_bases
ATGTCGCTCTTCTCCGCTGTCCAGCTTGCTCCCCGCGACCCGATCCTGGGCCTGAACGAAGCCTTCAACGCCGATGCGCG
TCCGACCAAGGTCAACCTCGGCGTCGGTGTGTACACGAACGAAGACGGCAAGATTCCGCTGCTGCGCGCGGTGCGCGACG
CGGAGAAGGCACGTGTCGAGGCCGGCCTGCCGCGCGGCTACCTGCCGATCGACGGGATCGCCGCCTACGATGCGGCCGTG
CAGAAGCTGCTGCTCGGCAACGACTCGCCGCTGATCGCGGCGGGCCGCGTGGTCACGGCCCAGGCACTGGGCGGCACGGG
CGCGCTGAAGATCGGCGCCGATTTCCTGCGCACCCTGAATCCGAACGTGAAGGTCGCGATCAGCGATCCCAGCTGGGAAA
ACCACCGCGCGCTGTTCGAAGCGGCCGGCTTCGAAGTCGTCGCGTACCCGTATTACGATGCGGCCACGAACGGCGTGAAC
TTCGAAGGCATGCTGTCGGCGCTGAACGGCTACGCGGCCGGCACGGTCGTCGTGCTGCACGCGTGCTGCCACAACCCGAC
CGGCGTGGATCTCACCGAAGCGCAATGGCAACAGGTCGTCGACGTCGTGAAGGCGCGCAACCTCGTGCCGTTCCTCGACA
TGGCCTACCAGGGCTTCGGCGAGAACATCGAAGCCGATGCCGCCGCCGTGCGCCTGTTTGCCGCAGCCGACCTGAACGCG
TTCGTGTCGTCGTCGTTCTCGAAGTCGTTCTCGCTGTACGGCGAGCGTGTCGGCGCGCTGTCGATCATCACGTCGAGCAA
GGAAGAAGCCACGCGCGTGCTGTCGCAACTGAAGCGCGTGATCCGCACGAACTACTCGAACCCGCCGACCCACGGCGGCG
CGGTGGTCGCAGCCGTGCTCGCATCGCCGGAACTGCACGCTTCGTGGGTGCAGGAACTCGGCGAAATGCGCGATCGCATC
CGCGCGATGCGCAATGGTCTCGTCGAGCGCCTGAAGGCAAGCGGCGTCGATCGCGATTTCAGCTTCATCAACGCGCAGCG
CGGGATGTTCTCGTATTCGGGCCTGACCTCGGCACAAGTCGATCGCCTGCGCGACGAGTTCGGCATCTATGCGGTCGGCA
CCGGCCGAATCTGCGTCGCCGCGCTGAACACGCGCAACCTCGACGCGGTCGCCAATGCGGTCGCAGCGGTCCTGAAGTAA

Upstream 100 bases:

>100_bases
TCAGGCTGCTGCGCTTCCCGGCGTCGCGCCGTGGGCGCGGTCCATGCGCCCGCCCCGCCGGCTGAAAGCCTGACCCTCTT
TTCACTACTGCCGAATCATC

Downstream 100 bases:

>100_bases
AGCCGTGCCGGGGCGGCAACCGTCACCGCCCTGCCCTGCCGACATGAAAAACGCGCTCCATGGAGCGCGTTTTTTTGTGC
CGTCCAGTCCAGCGCGGCGG

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MSLFSAVQLAPRDPILGLNEAFNADARPTKVNLGVGVYTNEDGKIPLLRAVRDAEKARVEAGLPRGYLPIDGIAAYDAAV
QKLLLGNDSPLIAAGRVVTAQALGGTGALKIGADFLRTLNPNVKVAISDPSWENHRALFEAAGFEVVAYPYYDAATNGVN
FEGMLSALNGYAAGTVVVLHACCHNPTGVDLTEAQWQQVVDVVKARNLVPFLDMAYQGFGENIEADAAAVRLFAAADLNA
FVSSSFSKSFSLYGERVGALSIITSSKEEATRVLSQLKRVIRTNYSNPPTHGGAVVAAVLASPELHASWVQELGEMRDRI
RAMRNGLVERLKASGVDRDFSFINAQRGMFSYSGLTSAQVDRLRDEFGIYAVGTGRICVAALNTRNLDAVANAVAAVLK

Sequences:

>Translated_399_residues
MSLFSAVQLAPRDPILGLNEAFNADARPTKVNLGVGVYTNEDGKIPLLRAVRDAEKARVEAGLPRGYLPIDGIAAYDAAV
QKLLLGNDSPLIAAGRVVTAQALGGTGALKIGADFLRTLNPNVKVAISDPSWENHRALFEAAGFEVVAYPYYDAATNGVN
FEGMLSALNGYAAGTVVVLHACCHNPTGVDLTEAQWQQVVDVVKARNLVPFLDMAYQGFGENIEADAAAVRLFAAADLNA
FVSSSFSKSFSLYGERVGALSIITSSKEEATRVLSQLKRVIRTNYSNPPTHGGAVVAAVLASPELHASWVQELGEMRDRI
RAMRNGLVERLKASGVDRDFSFINAQRGMFSYSGLTSAQVDRLRDEFGIYAVGTGRICVAALNTRNLDAVANAVAAVLK
>Mature_398_residues
SLFSAVQLAPRDPILGLNEAFNADARPTKVNLGVGVYTNEDGKIPLLRAVRDAEKARVEAGLPRGYLPIDGIAAYDAAVQ
KLLLGNDSPLIAAGRVVTAQALGGTGALKIGADFLRTLNPNVKVAISDPSWENHRALFEAAGFEVVAYPYYDAATNGVNF
EGMLSALNGYAAGTVVVLHACCHNPTGVDLTEAQWQQVVDVVKARNLVPFLDMAYQGFGENIEADAAAVRLFAAADLNAF
VSSSFSKSFSLYGERVGALSIITSSKEEATRVLSQLKRVIRTNYSNPPTHGGAVVAAVLASPELHASWVQELGEMRDRIR
AMRNGLVERLKASGVDRDFSFINAQRGMFSYSGLTSAQVDRLRDEFGIYAVGTGRICVAALNTRNLDAVANAVAAVLK

Specific function: Biosynthesis of Phe, Tyr, Asp and Leu. [C]

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=398, Percent_Identity=43.7185929648241, Blast_Score=340, Evalue=1e-93,
Organism=Homo sapiens, GI4504067, Length=401, Percent_Identity=43.640897755611, Blast_Score=330, Evalue=2e-90,
Organism=Homo sapiens, GI117414139, Length=399, Percent_Identity=27.3182957393484, Blast_Score=168, Evalue=6e-42,
Organism=Escherichia coli, GI1790488, Length=399, Percent_Identity=54.8872180451128, Blast_Score=435, Evalue=1e-123,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=47.979797979798, Blast_Score=395, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI71981858, Length=400, Percent_Identity=42.25, Blast_Score=348, Evalue=4e-96,
Organism=Caenorhabditis elegans, GI25147133, Length=399, Percent_Identity=41.8546365914787, Blast_Score=333, Evalue=1e-91,
Organism=Caenorhabditis elegans, GI17569539, Length=402, Percent_Identity=39.0547263681592, Blast_Score=296, Evalue=9e-81,
Organism=Caenorhabditis elegans, GI17569537, Length=396, Percent_Identity=33.5858585858586, Blast_Score=219, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI25147136, Length=213, Percent_Identity=41.3145539906103, Blast_Score=184, Evalue=6e-47,
Organism=Caenorhabditis elegans, GI17550384, Length=269, Percent_Identity=34.5724907063197, Blast_Score=179, Evalue=3e-45,
Organism=Saccharomyces cerevisiae, GI6323055, Length=408, Percent_Identity=37.5, Blast_Score=293, Evalue=2e-80,
Organism=Saccharomyces cerevisiae, GI6322743, Length=436, Percent_Identity=33.256880733945, Blast_Score=243, Evalue=3e-65,
Organism=Drosophila melanogaster, GI24580972, Length=400, Percent_Identity=42.25, Blast_Score=325, Evalue=2e-89,
Organism=Drosophila melanogaster, GI24580970, Length=400, Percent_Identity=42.25, Blast_Score=325, Evalue=3e-89,
Organism=Drosophila melanogaster, GI19920542, Length=393, Percent_Identity=41.9847328244275, Blast_Score=317, Evalue=9e-87,
Organism=Drosophila melanogaster, GI24654046, Length=402, Percent_Identity=40.547263681592, Blast_Score=306, Evalue=1e-83,
Organism=Drosophila melanogaster, GI19922362, Length=402, Percent_Identity=40.547263681592, Blast_Score=306, Evalue=2e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42562; Mature: 42431

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFSAVQLAPRDPILGLNEAFNADARPTKVNLGVGVYTNEDGKIPLLRAVRDAEKARVE
CCHHHHHHCCCCCCCCCCHHHCCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHH
AGLPRGYLPIDGIAAYDAAVQKLLLGNDSPLIAAGRVVTAQALGGTGALKIGADFLRTLN
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCEEEEECCCCCCEEHHHHHHHHHCC
PNVKVAISDPSWENHRALFEAAGFEVVAYPYYDAATNGVNFEGMLSALNGYAAGTVVVLH
CCEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCHHHHHHHH
ACCHNPTGVDLTEAQWQQVVDVVKARNLVPFLDMAYQGFGENIEADAAAVRLFAAADLNA
HHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
FVSSSFSKSFSLYGERVGALSIITSSKEEATRVLSQLKRVIRTNYSNPPTHGGAVVAAVL
HHHHHHHHHHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
ASPELHASWVQELGEMRDRIRAMRNGLVERLKASGVDRDFSFINAQRGMFSYSGLTSAQV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEECCCCCHHHH
DRLRDEFGIYAVGTGRICVAALNTRNLDAVANAVAAVLK
HHHHHHCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHC
>Mature Secondary Structure 
SLFSAVQLAPRDPILGLNEAFNADARPTKVNLGVGVYTNEDGKIPLLRAVRDAEKARVE
CHHHHHHCCCCCCCCCCHHHCCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHH
AGLPRGYLPIDGIAAYDAAVQKLLLGNDSPLIAAGRVVTAQALGGTGALKIGADFLRTLN
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCEEEEECCCCCCEEHHHHHHHHHCC
PNVKVAISDPSWENHRALFEAAGFEVVAYPYYDAATNGVNFEGMLSALNGYAAGTVVVLH
CCEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCHHHHHHHH
ACCHNPTGVDLTEAQWQQVVDVVKARNLVPFLDMAYQGFGENIEADAAAVRLFAAADLNA
HHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
FVSSSFSKSFSLYGERVGALSIITSSKEEATRVLSQLKRVIRTNYSNPPTHGGAVVAAVL
HHHHHHHHHHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
ASPELHASWVQELGEMRDRIRAMRNGLVERLKASGVDRDFSFINAQRGMFSYSGLTSAQV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEECCCCCHHHH
DRLRDEFGIYAVGTGRICVAALNTRNLDAVANAVAAVLK
HHHHHHCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043; 8808952 [H]