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The map label for this gene is exbB [H]

Identifier: 116690220

GI number: 116690220

Start: 2450522

End: 2451256

Strand: Direct

Name: exbB [H]

Synonym: Bcen2424_2199

Alternate gene names: 116690220

Gene position: 2450522-2451256 (Clockwise)

Preceding gene: 116690219

Following gene: 116690221

Centisome position: 70.34

GC content: 65.58

Gene sequence:

>735_bases
ATGCAAAGCTACGGTATCGCGCACGTCTGGGCGCAAGGTGATTTCGTCACGCGCGCCATTGCGATCACGCTGCTCGTGAT
GTCGGTCCTGTCGTGGATCGTGATCGTCATCAAGGGCTGGAACGTGATTCGCCTGAACCGCCTCACGAAGAACGCCGAAC
AGGCATTCTGGCATTCCGACAATTTCGACGACGGCATCAAGAAGCTCGGCCTCGCCGCATCGACGCCGAACGACAATCCG
TTCCTCGCGCTCGCGCTGTCGGGCAAGGAAGCCGCCGACCACCACCATCAGACGCAACCGCACCTGCACGACCGCATGGA
CGTGTCGGACTGGGTCACGCGCTGCCTGAAGGACACGATGGACGAAGGCATCTCGCGTATGCAGAGCGGCCTCGCGATCC
TCGCATCGGTCGGCAGCACGGCGCCGTTCGTCGGCCTGTTCGGCACGGTCTGGGGCATCTACCACGCGCTGCTCGCGATC
GGTGCCACCGGCCAGACGTCGATCGACCAGGTCGCGGGCCCGGTCGGCGAATCGCTGATCATGACGGCCTTCGGCCTGTT
CGTCGCGATTCCCGCGGTGCTCGGCTACAACGCGCTGACCCGCGCGAACAAGGGCGTCGTCAGCAAGCTCCGCCGCTTCG
CGCACGGTCTGCACGCGTACTTCGTGACGGGTGCGAGCCTCGCGTCGTCGTCGACGCGCGACGGTCTGCGTCTCGCATCG
CGCGCCGCCAGCTGA

Upstream 100 bases:

>100_bases
GTCGAGAACGGCCAGGCGATCCGCGCCGCCCGCACACAGCCCTACAGCTTCGGGCTCACCGACTAACCTGCCTCATCCGG
AAGATTCAAAGGAAACAAAA

Downstream 100 bases:

>100_bases
GACGAGGTGAACCATGGCCATGAACACCGGTTTCAGCGACGATGACGACGATGCCGTGATGAGCGAGATCAACATGACGC
CGCTCGTCGACGTCATGCTC

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MQSYGIAHVWAQGDFVTRAIAITLLVMSVLSWIVIVIKGWNVIRLNRLTKNAEQAFWHSDNFDDGIKKLGLAASTPNDNP
FLALALSGKEAADHHHQTQPHLHDRMDVSDWVTRCLKDTMDEGISRMQSGLAILASVGSTAPFVGLFGTVWGIYHALLAI
GATGQTSIDQVAGPVGESLIMTAFGLFVAIPAVLGYNALTRANKGVVSKLRRFAHGLHAYFVTGASLASSSTRDGLRLAS
RAAS

Sequences:

>Translated_244_residues
MQSYGIAHVWAQGDFVTRAIAITLLVMSVLSWIVIVIKGWNVIRLNRLTKNAEQAFWHSDNFDDGIKKLGLAASTPNDNP
FLALALSGKEAADHHHQTQPHLHDRMDVSDWVTRCLKDTMDEGISRMQSGLAILASVGSTAPFVGLFGTVWGIYHALLAI
GATGQTSIDQVAGPVGESLIMTAFGLFVAIPAVLGYNALTRANKGVVSKLRRFAHGLHAYFVTGASLASSSTRDGLRLAS
RAAS
>Mature_244_residues
MQSYGIAHVWAQGDFVTRAIAITLLVMSVLSWIVIVIKGWNVIRLNRLTKNAEQAFWHSDNFDDGIKKLGLAASTPNDNP
FLALALSGKEAADHHHQTQPHLHDRMDVSDWVTRCLKDTMDEGISRMQSGLAILASVGSTAPFVGLFGTVWGIYHALLAI
GATGQTSIDQVAGPVGESLIMTAFGLFVAIPAVLGYNALTRANKGVVSKLRRFAHGLHAYFVTGASLASSSTRDGLRLAS
RAAS

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=215, Percent_Identity=31.6279069767442, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1789381, Length=193, Percent_Identity=28.4974093264249, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 26194; Mature: 26194

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSYGIAHVWAQGDFVTRAIAITLLVMSVLSWIVIVIKGWNVIRLNRLTKNAEQAFWHSD
CCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCC
NFDDGIKKLGLAASTPNDNPFLALALSGKEAADHHHQTQPHLHDRMDVSDWVTRCLKDTM
CHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHH
DEGISRMQSGLAILASVGSTAPFVGLFGTVWGIYHALLAIGATGQTSIDQVAGPVGESLI
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHH
MTAFGLFVAIPAVLGYNALTRANKGVVSKLRRFAHGLHAYFVTGASLASSSTRDGLRLAS
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
RAAS
HCCC
>Mature Secondary Structure
MQSYGIAHVWAQGDFVTRAIAITLLVMSVLSWIVIVIKGWNVIRLNRLTKNAEQAFWHSD
CCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCC
NFDDGIKKLGLAASTPNDNPFLALALSGKEAADHHHQTQPHLHDRMDVSDWVTRCLKDTM
CHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHH
DEGISRMQSGLAILASVGSTAPFVGLFGTVWGIYHALLAIGATGQTSIDQVAGPVGESLI
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHH
MTAFGLFVAIPAVLGYNALTRANKGVVSKLRRFAHGLHAYFVTGASLASSSTRDGLRLAS
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
RAAS
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9371459 [H]