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The map label for this gene is pgl [H]

Identifier: 116690203

GI number: 116690203

Start: 2431248

End: 2432297

Strand: Direct

Name: pgl [H]

Synonym: Bcen2424_2182

Alternate gene names: 116690203

Gene position: 2431248-2432297 (Clockwise)

Preceding gene: 116690202

Following gene: 116690205

Centisome position: 69.79

GC content: 73.05

Gene sequence:

>1050_bases
ATGCCGAACACTGACCGCCTGACCGTCGTCGTCTCGAACGCCGTCGACGGCGACCTCGCCACCTTCGCCCTCACCGGCGA
CGGCACGCTCGCGCCGCTCGCCCGCTATCCGGCCGCCGACGTCGCGATGCCGATCGCCGTGCAGGCCGACCGCACGCGGC
TCTACGTCGCGACGCGCGGCGAGCAGCCGACGATCGTCGCGTTCCGCGTCGCCGCCGCCACGGGCGCGCTCGCACGCATC
GGCACGACCGCGATCGACGCGAGCCATGCGTACCTGTCGCTCGACCGCAGCGGCCGCTGGCTGCTCGGCGCGTCGTACGG
CGGGAATTCGCTGAGCCTCTACGACGCCGCCCGCGTGCGCGACGGCGACGGCACGCCGCTGCAAGTCGCGGGCGGCATCG
CGAACGCGCATGCGGTGATCGTATCGCCGGACAACCGTTTCGCGTACGTCAGCTCGCTCGGCTCGGACCGCGTGTTCGGC
TTCGCGCTCGTCGAGGACGCCGCCGGCCTGCGCGCGGTCGAACACGGCGACACGCGCGTGCCCGCCGGCTTCGGCCCGCG
TCACCTGCGGTTCGCGGATGACGGCCGCACGCTGGTCGTCGTCAGCGAATTCCAGGGAACGCTCGCGACCTTCGCCCGCG
ACACCAACACCGGCCGGCTCGGCGATCCACACGTGAGCGCGCGCCATCCGGCCGTCGTCGAACTCGCGCAAGGCCATGCG
CGCCCGCCCGCCCCGACCGAACCGTCCGTGTGGGCCGCCGATCTGCATCTGACGCCCGACGAGCGTTTCGCGTACGTCAG
CGAGCGCACGTCGAGCCGGTTGCTCGGCTACCGCCGCAACGAAGACGGCACGTTCGAGCCGACCCACGCGACGCCCACCG
AGACGCAGCCGCGCGGCTTCGCGATCGATCCGTCGGGGCGCTGGCTCGTCGCCTGCGGCGAGCAGTCGGAGCACGTGGCC
GTGTATGCGATCGCGCCGGACGACGGCACGCTGTCGCTGCATATGCGCGTGCCGGGCGGCCGCGGCGCGAACTGGATCGC
GATCGTCTGA

Upstream 100 bases:

>100_bases
GCCGCGGTCGCCGCGCTGTTCGCGCGCACGCACCGGCGCAGCGATCCGCCGCGCGGCCAGCCGGCCGACGAATCCTTCTC
GCACGCCTCGATGCTCCGCC

Downstream 100 bases:

>100_bases
AAGCTTGAAGGTTTGAAGAAGCATCCGCACCTGCGCGAGAACCGGCAAGCCGATGCGGGGGCGACGTTCAGCGCCGCGCG
CTCGGCGCCACGCCCGTCCA

Product: 3-carboxymuconate cyclase-like protein

Products: NA

Alternate protein names: 6-P-gluconolactonase [H]

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MPNTDRLTVVVSNAVDGDLATFALTGDGTLAPLARYPAADVAMPIAVQADRTRLYVATRGEQPTIVAFRVAAATGALARI
GTTAIDASHAYLSLDRSGRWLLGASYGGNSLSLYDAARVRDGDGTPLQVAGGIANAHAVIVSPDNRFAYVSSLGSDRVFG
FALVEDAAGLRAVEHGDTRVPAGFGPRHLRFADDGRTLVVVSEFQGTLATFARDTNTGRLGDPHVSARHPAVVELAQGHA
RPPAPTEPSVWAADLHLTPDERFAYVSERTSSRLLGYRRNEDGTFEPTHATPTETQPRGFAIDPSGRWLVACGEQSEHVA
VYAIAPDDGTLSLHMRVPGGRGANWIAIV

Sequences:

>Translated_349_residues
MPNTDRLTVVVSNAVDGDLATFALTGDGTLAPLARYPAADVAMPIAVQADRTRLYVATRGEQPTIVAFRVAAATGALARI
GTTAIDASHAYLSLDRSGRWLLGASYGGNSLSLYDAARVRDGDGTPLQVAGGIANAHAVIVSPDNRFAYVSSLGSDRVFG
FALVEDAAGLRAVEHGDTRVPAGFGPRHLRFADDGRTLVVVSEFQGTLATFARDTNTGRLGDPHVSARHPAVVELAQGHA
RPPAPTEPSVWAADLHLTPDERFAYVSERTSSRLLGYRRNEDGTFEPTHATPTETQPRGFAIDPSGRWLVACGEQSEHVA
VYAIAPDDGTLSLHMRVPGGRGANWIAIV
>Mature_348_residues
PNTDRLTVVVSNAVDGDLATFALTGDGTLAPLARYPAADVAMPIAVQADRTRLYVATRGEQPTIVAFRVAAATGALARIG
TTAIDASHAYLSLDRSGRWLLGASYGGNSLSLYDAARVRDGDGTPLQVAGGIANAHAVIVSPDNRFAYVSSLGSDRVFGF
ALVEDAAGLRAVEHGDTRVPAGFGPRHLRFADDGRTLVVVSEFQGTLATFARDTNTGRLGDPHVSARHPAVVELAQGHAR
PPAPTEPSVWAADLHLTPDERFAYVSERTSSRLLGYRRNEDGTFEPTHATPTETQPRGFAIDPSGRWLVACGEQSEHVAV
YAIAPDDGTLSLHMRVPGGRGANWIAIV

Specific function: Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate [H]

COG id: COG2706

COG function: function code G; 3-carboxymuconate cyclase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cycloisomerase 2 family [H]

Homologues:

Organism=Escherichia coli, GI1786983, Length=347, Percent_Identity=30.2593659942363, Blast_Score=158, Evalue=5e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022528
- InterPro:   IPR019405
- InterPro:   IPR011045
- InterPro:   IPR015943 [H]

Pfam domain/function: PF10282 DUF2394 [H]

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 36941; Mature: 36809

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNTDRLTVVVSNAVDGDLATFALTGDGTLAPLARYPAADVAMPIAVQADRTRLYVATRG
CCCCCEEEEEEECCCCCCEEEEEEECCCCCCHHHHCCCCCCEEEEEEEECCEEEEEEECC
EQPTIVAFRVAAATGALARIGTTAIDASHAYLSLDRSGRWLLGASYGGNSLSLYDAARVR
CCCEEEEEEEEHHCCCHHHCCCEEEECCEEEEEECCCCCEEEEECCCCCEEEEEEEEEEE
DGDGTPLQVAGGIANAHAVIVSPDNRFAYVSSLGSDRVFGFALVEDAAGLRAVEHGDTRV
CCCCCEEEEECCCCCCEEEEECCCCCEEEEECCCCCCEEEEEEEECCCCCEEEECCCCCC
PAGFGPRHLRFADDGRTLVVVSEFQGTLATFARDTNTGRLGDPHVSARHPAVVELAQGHA
CCCCCCCEEEEECCCCEEEEEECCCCCEEHHEECCCCCCCCCCCCCCCCCCEEEECCCCC
RPPAPTEPSVWAADLHLTPDERFAYVSERTSSRLLGYRRNEDGTFEPTHATPTETQPRGF
CCCCCCCCCEEEEEEEECCHHHEEEEHHCCCHHHEEEEECCCCCCCCCCCCCCCCCCCCE
AIDPSGRWLVACGEQSEHVAVYAIAPDDGTLSLHMRVPGGRGANWIAIV
EECCCCCEEEEECCCCCCEEEEEECCCCCEEEEEEECCCCCCCCEEEEC
>Mature Secondary Structure 
PNTDRLTVVVSNAVDGDLATFALTGDGTLAPLARYPAADVAMPIAVQADRTRLYVATRG
CCCCEEEEEEECCCCCCEEEEEEECCCCCCHHHHCCCCCCEEEEEEEECCEEEEEEECC
EQPTIVAFRVAAATGALARIGTTAIDASHAYLSLDRSGRWLLGASYGGNSLSLYDAARVR
CCCEEEEEEEEHHCCCHHHCCCEEEECCEEEEEECCCCCEEEEECCCCCEEEEEEEEEEE
DGDGTPLQVAGGIANAHAVIVSPDNRFAYVSSLGSDRVFGFALVEDAAGLRAVEHGDTRV
CCCCCEEEEECCCCCCEEEEECCCCCEEEEECCCCCCEEEEEEEECCCCCEEEECCCCCC
PAGFGPRHLRFADDGRTLVVVSEFQGTLATFARDTNTGRLGDPHVSARHPAVVELAQGHA
CCCCCCCEEEEECCCCEEEEEECCCCCEEHHEECCCCCCCCCCCCCCCCCCEEEECCCCC
RPPAPTEPSVWAADLHLTPDERFAYVSERTSSRLLGYRRNEDGTFEPTHATPTETQPRGF
CCCCCCCCCEEEEEEEECCHHHEEEEHHCCCHHHEEEEECCCCCCCCCCCCCCCCCCCCE
AIDPSGRWLVACGEQSEHVAVYAIAPDDGTLSLHMRVPGGRGANWIAIV
EECCCCCEEEEECCCCCCEEEEEECCCCCEEEEEEECCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA