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The map label for this gene is ttuB [H]

Identifier: 116690202

GI number: 116690202

Start: 2429894

End: 2431261

Strand: Direct

Name: ttuB [H]

Synonym: Bcen2424_2181

Alternate gene names: 116690202

Gene position: 2429894-2431261 (Clockwise)

Preceding gene: 116690198

Following gene: 116690203

Centisome position: 69.75

GC content: 67.25

Gene sequence:

>1368_bases
TTGAACCCGCCCTCGTCCGCCCTGCCCGGCCGCGACCCGCTCGCGTCCGCCGTCTCGAAAGTGAAATGGCACGTGCTGCC
GCTCGTGCTGATCATGTTCATCGCGAACTACATCGACCGCGTGAACGTCGGCTTCGTCGATCGCCACCTCGAAGCGTCGA
TCGGCATCGGCGCGGCCGCGTACGGGCTCGGCGCCGGGCTGTTCTTCGTCGGCTACGCGCTGTTCGAAGTGCCGTCGAAC
CTGCTGATGCAGCGCTACGGCGCGCGCATCTGGCTCGCGCGGATCATGGCGACGTGGGGCATCGTCGCGGCCGCGATGGC
GTTCGTGTGGAACGACACGTCGTTCTACGCGCTGCGCTTCCTGCTCGGCGCGGCCGAGGCCGGCTTCTTCCCCGGCGTCG
TGCTGTACCTGTCGCAATGGCTGCCGCCGCAGGAACGCGGCAAGGCGATGGCGATCTTCCTCGGCGGCTCCGCGTTCGCA
TCGGTGCTGTCCGGGCCCGTCACCGGCGCGCTGCTGTCGATCCGCGGCTTCGGCCTGGAAGGCTGGCAATGGATGTTCCT
GATCGAAGGGCTATTCTCGGTCGCGCTGTGCGGCGCGAGCTGGCTGCTGCTGAAATCGCATATCCGCGATGCGACGTGGC
TCACCGCCGAAGAACGCACGGCGCTGCAGAACGCACTCGACGACGAGCGCGCGACGCGCGACGTCCGCTCGAACGTGCCG
GTGCGCGCCACCACGCTGCTGCGCGATCCGCAGATCATGCTGTTCTGCTTCCTGTACTTCTCGATCCAGCTGACGATCTA
CGCAGCCACGTTCTGGCTGCCGACCATCATCCGCAAGATGGGTGGCCTCACCGATTTCCAGGTCGGCCTGTACAACACGA
TTCCGTGGATGATCGCGATCGGCGCGATGTACGGCTTCGCGGTGCTGTCGTCGAAGTGGAAGCATCCGCAGCGTTGGCTC
GCGTGCGCGCTCGTGCTGGCCGCGTGCGGGCTGTTCGCGTCGACGTCGCATGATCCGGTATGGTCGTTCGCGTCGATCTG
CTTCGCCGCGCTCGGCTTCAAGGCCGCGTCGTCGCTGTTCTGGCCGATTCCACAGGGCTACCTCGACACGCGGGTGGCCG
CGGCCGTGATCGCGCTGATCAACTCGGTCGGCAACCTCGGCGGTTTCGTCGCGCCGACGGCCTTCGGCTATCTAAAGCAA
CATACGGGTTCGATCACGGGCGGGCTGTATGCGCTCGCGATCGCTTCGCTCGTCGCCGCGGTCGCCGCGCTGTTCGCGCG
CACGCACCGGCGCAGCGATCCGCCGCGCGGCCAGCCGGCCGACGAATCCTTCTCGCACGCCTCGATGCTCCGCCATGCCG
AACACTGA

Upstream 100 bases:

>100_bases
CCGGCGTACCATGTCATACGACGACGTACTACATTGAATCGGCATCCAGACGCCAACGCGGGCCGCCGCCCCGTCCGCCG
TCACCCGACCGGAGACACCC

Downstream 100 bases:

>100_bases
CCGCCTGACCGTCGTCGTCTCGAACGCCGTCGACGGCGACCTCGCCACCTTCGCCCTCACCGGCGACGGCACGCTCGCGC
CGCTCGCCCGCTATCCGGCC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MNPPSSALPGRDPLASAVSKVKWHVLPLVLIMFIANYIDRVNVGFVDRHLEASIGIGAAAYGLGAGLFFVGYALFEVPSN
LLMQRYGARIWLARIMATWGIVAAAMAFVWNDTSFYALRFLLGAAEAGFFPGVVLYLSQWLPPQERGKAMAIFLGGSAFA
SVLSGPVTGALLSIRGFGLEGWQWMFLIEGLFSVALCGASWLLLKSHIRDATWLTAEERTALQNALDDERATRDVRSNVP
VRATTLLRDPQIMLFCFLYFSIQLTIYAATFWLPTIIRKMGGLTDFQVGLYNTIPWMIAIGAMYGFAVLSSKWKHPQRWL
ACALVLAACGLFASTSHDPVWSFASICFAALGFKAASSLFWPIPQGYLDTRVAAAVIALINSVGNLGGFVAPTAFGYLKQ
HTGSITGGLYALAIASLVAAVAALFARTHRRSDPPRGQPADESFSHASMLRHAEH

Sequences:

>Translated_455_residues
MNPPSSALPGRDPLASAVSKVKWHVLPLVLIMFIANYIDRVNVGFVDRHLEASIGIGAAAYGLGAGLFFVGYALFEVPSN
LLMQRYGARIWLARIMATWGIVAAAMAFVWNDTSFYALRFLLGAAEAGFFPGVVLYLSQWLPPQERGKAMAIFLGGSAFA
SVLSGPVTGALLSIRGFGLEGWQWMFLIEGLFSVALCGASWLLLKSHIRDATWLTAEERTALQNALDDERATRDVRSNVP
VRATTLLRDPQIMLFCFLYFSIQLTIYAATFWLPTIIRKMGGLTDFQVGLYNTIPWMIAIGAMYGFAVLSSKWKHPQRWL
ACALVLAACGLFASTSHDPVWSFASICFAALGFKAASSLFWPIPQGYLDTRVAAAVIALINSVGNLGGFVAPTAFGYLKQ
HTGSITGGLYALAIASLVAAVAALFARTHRRSDPPRGQPADESFSHASMLRHAEH
>Mature_455_residues
MNPPSSALPGRDPLASAVSKVKWHVLPLVLIMFIANYIDRVNVGFVDRHLEASIGIGAAAYGLGAGLFFVGYALFEVPSN
LLMQRYGARIWLARIMATWGIVAAAMAFVWNDTSFYALRFLLGAAEAGFFPGVVLYLSQWLPPQERGKAMAIFLGGSAFA
SVLSGPVTGALLSIRGFGLEGWQWMFLIEGLFSVALCGASWLLLKSHIRDATWLTAEERTALQNALDDERATRDVRSNVP
VRATTLLRDPQIMLFCFLYFSIQLTIYAATFWLPTIIRKMGGLTDFQVGLYNTIPWMIAIGAMYGFAVLSSKWKHPQRWL
ACALVLAACGLFASTSHDPVWSFASICFAALGFKAASSLFWPIPQGYLDTRVAAAVIALINSVGNLGGFVAPTAFGYLKQ
HTGSITGGLYALAIASLVAAVAALFARTHRRSDPPRGQPADESFSHASMLRHAEH

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=419, Percent_Identity=33.890214797136, Blast_Score=236, Evalue=3e-63,
Organism=Escherichia coli, GI87082320, Length=451, Percent_Identity=21.9512195121951, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789515, Length=431, Percent_Identity=23.8979118329466, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1789152, Length=442, Percent_Identity=24.6606334841629, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI2367379, Length=444, Percent_Identity=23.4234234234234, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI2367193, Length=313, Percent_Identity=22.3642172523962, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI25141316, Length=400, Percent_Identity=23, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI25141318, Length=400, Percent_Identity=23, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI86561091, Length=255, Percent_Identity=22.7450980392157, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322025, Length=249, Percent_Identity=25.3012048192771, Blast_Score=90, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6321698, Length=342, Percent_Identity=22.8070175438596, Blast_Score=80, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6319876, Length=235, Percent_Identity=24.6808510638298, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24639764, Length=356, Percent_Identity=25, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI20130167, Length=374, Percent_Identity=22.7272727272727, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24641682, Length=381, Percent_Identity=24.9343832020997, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24654215, Length=372, Percent_Identity=22.3118279569892, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19922400, Length=372, Percent_Identity=22.3118279569892, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49437; Mature: 49437

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPPSSALPGRDPLASAVSKVKWHVLPLVLIMFIANYIDRVNVGFVDRHLEASIGIGAAA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHH
YGLGAGLFFVGYALFEVPSNLLMQRYGARIWLARIMATWGIVAAAMAFVWNDTSFYALRF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LLGAAEAGFFPGVVLYLSQWLPPQERGKAMAIFLGGSAFASVLSGPVTGALLSIRGFGLE
HHHHHHCCCHHHHHHHHHHCCCHHHCCCEEEEEECCHHHHHHHCCCHHHHHHHHHCCCCC
GWQWMFLIEGLFSVALCGASWLLLKSHIRDATWLTAEERTALQNALDDERATRDVRSNVP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
VRATTLLRDPQIMLFCFLYFSIQLTIYAATFWLPTIIRKMGGLTDFQVGLYNTIPWMIAI
EEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHH
GAMYGFAVLSSKWKHPQRWLACALVLAACGLFASTSHDPVWSFASICFAALGFKAASSLF
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHC
WPIPQGYLDTRVAAAVIALINSVGNLGGFVAPTAFGYLKQHTGSITGGLYALAIASLVAA
CCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VAALFARTHRRSDPPRGQPADESFSHASMLRHAEH
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MNPPSSALPGRDPLASAVSKVKWHVLPLVLIMFIANYIDRVNVGFVDRHLEASIGIGAAA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHH
YGLGAGLFFVGYALFEVPSNLLMQRYGARIWLARIMATWGIVAAAMAFVWNDTSFYALRF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LLGAAEAGFFPGVVLYLSQWLPPQERGKAMAIFLGGSAFASVLSGPVTGALLSIRGFGLE
HHHHHHCCCHHHHHHHHHHCCCHHHCCCEEEEEECCHHHHHHHCCCHHHHHHHHHCCCCC
GWQWMFLIEGLFSVALCGASWLLLKSHIRDATWLTAEERTALQNALDDERATRDVRSNVP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
VRATTLLRDPQIMLFCFLYFSIQLTIYAATFWLPTIIRKMGGLTDFQVGLYNTIPWMIAI
EEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHH
GAMYGFAVLSSKWKHPQRWLACALVLAACGLFASTSHDPVWSFASICFAALGFKAASSLF
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHC
WPIPQGYLDTRVAAAVIALINSVGNLGGFVAPTAFGYLKQHTGSITGGLYALAIASLVAA
CCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VAALFARTHRRSDPPRGQPADESFSHASMLRHAEH
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]