Click here to switch to the map view.

The map label for this gene is dapL [H]

Identifier: 116690050

GI number: 116690050

Start: 2252347

End: 2253579

Strand: Direct

Name: dapL [H]

Synonym: Bcen2424_2029

Alternate gene names: 116690050

Gene position: 2252347-2253579 (Clockwise)

Preceding gene: 116690049

Following gene: 116690051

Centisome position: 64.65

GC content: 68.78

Gene sequence:

>1233_bases
ATGGCCGCTTCGCCCGTGAACCCTCGACTCGACTCGCTCCAGCCCTATCCCTTCGAAAAGCTGCGCGCCCTGTTCAAGGA
CGTGACGCCTTCCGGCGACCTCAAACCGATCAGCTTCGGCATCGGCGAGCCCAAACACGCGACGCCGGCGCTGATCCGCG
ACGCCGTGGTGGCCGCGCTCGACGGGCTCGCGTCGTACCCGGCCACGGCCGGCTCGGACGCGCTGCGCACGTCGATCGCG
CACTGGCTCGAGCGCCGCTACGGGCTGCCGGCAATCGATCCGGCCACGCAGGTGCTGCCGGTGTCGGGCTCGCGCGAAGC
GCTGTTCTCGCTCGCGCAGACGGTGATCGATGCACGGCCGTCCGCGGACGGCAAGAAGGCGATCGTACTCTGTCCGAATC
CTTTCTATCAAATTTACGAAGGCGCGGCGCTGCTCGCCGGTGCCGAACCCTATTTCGCGAACAGCGACCCGGCCCGCAAC
TTCGCGTGCGACTACGCGGCCGTGCCCGACGACGTGTGGGCGCGCACGCAGCTGCTGTACGTGTGCTCGCCCGGCAACCC
GACGGGCGCCGTGCTGACGCTCGACGACTGGCGCGAGCTGTTCGCGCTGTCGGACCGTCACGGTTTCGTGATCGCGTCCG
ACGAGTGCTATTCCGAGATCTATTTCGACGAAGCGGCGCCGCCGCTCGGCGGCCTCGAGGCCGCGCACCGCCTCGGCCGC
GGCTTCGAGCGGCTCGTGATGCTGTCGAGCCTGTCGAAGCGCTCGAACGTGCCGGGCATGCGCTCGGGCTTCGTCGCCGG
CGACGCCGCGCTGCTCAAGAAATTCCTGCTGTACCGCACGTACCACGGCGCCGCGCTGTCGCCGGTCTGGCAGCACGCGA
GCATCGCCGCATGGAACGACGAGGCGCACGTGCGCGAGAACCGCGCGCTGTACCTGCAGAAGTTCAACACGGTCACGCCG
ATGCTCGCCGACGTGATCGACGTGAAGCTGCCCGACGCCGCGTTCTACCTGTGGGCCAACGTGTCGCGCACCGGCCTGTC
GGACACCGAGTTCGCCCGCCGCCTGTACGCCGACTATAATGTGACGGTTCTGCCCGGCTCGTACCTGGCGCGCGATGCGC
ACGGCACGAACCCGGGCCGCGATTTCATCCGGATCGCGCTCGTCGCGGGCACCCCCGAATGCGTCGAGGGCGCGCAACGC
ATCGTCGATTTCTGCCGCGCTCTCGCGCGGTAA

Upstream 100 bases:

>100_bases
ATTGCGTCACGCTATAATCGTCCGTTGCGAGCCGCGCGCCCCGGCGCCCGTTCGCAGCCGCGCGGCGCGCCCGCCGCTTC
TTTCGCTCCAACCGGCCGCG

Downstream 100 bases:

>100_bases
GACGTCCATCCCGATCAATTCCATCCATCTCCTGCGAAAACGAACATGTCGCAACAACTTCAGCAAATCATCGATACCGC
CTGGGAAAACCGCGCCGAGC

Product: succinyldiaminopimelate transaminase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MAASPVNPRLDSLQPYPFEKLRALFKDVTPSGDLKPISFGIGEPKHATPALIRDAVVAALDGLASYPATAGSDALRTSIA
HWLERRYGLPAIDPATQVLPVSGSREALFSLAQTVIDARPSADGKKAIVLCPNPFYQIYEGAALLAGAEPYFANSDPARN
FACDYAAVPDDVWARTQLLYVCSPGNPTGAVLTLDDWRELFALSDRHGFVIASDECYSEIYFDEAAPPLGGLEAAHRLGR
GFERLVMLSSLSKRSNVPGMRSGFVAGDAALLKKFLLYRTYHGAALSPVWQHASIAAWNDEAHVRENRALYLQKFNTVTP
MLADVIDVKLPDAAFYLWANVSRTGLSDTEFARRLYADYNVTVLPGSYLARDAHGTNPGRDFIRIALVAGTPECVEGAQR
IVDFCRALAR

Sequences:

>Translated_410_residues
MAASPVNPRLDSLQPYPFEKLRALFKDVTPSGDLKPISFGIGEPKHATPALIRDAVVAALDGLASYPATAGSDALRTSIA
HWLERRYGLPAIDPATQVLPVSGSREALFSLAQTVIDARPSADGKKAIVLCPNPFYQIYEGAALLAGAEPYFANSDPARN
FACDYAAVPDDVWARTQLLYVCSPGNPTGAVLTLDDWRELFALSDRHGFVIASDECYSEIYFDEAAPPLGGLEAAHRLGR
GFERLVMLSSLSKRSNVPGMRSGFVAGDAALLKKFLLYRTYHGAALSPVWQHASIAAWNDEAHVRENRALYLQKFNTVTP
MLADVIDVKLPDAAFYLWANVSRTGLSDTEFARRLYADYNVTVLPGSYLARDAHGTNPGRDFIRIALVAGTPECVEGAQR
IVDFCRALAR
>Mature_409_residues
AASPVNPRLDSLQPYPFEKLRALFKDVTPSGDLKPISFGIGEPKHATPALIRDAVVAALDGLASYPATAGSDALRTSIAH
WLERRYGLPAIDPATQVLPVSGSREALFSLAQTVIDARPSADGKKAIVLCPNPFYQIYEGAALLAGAEPYFANSDPARNF
ACDYAAVPDDVWARTQLLYVCSPGNPTGAVLTLDDWRELFALSDRHGFVIASDECYSEIYFDEAAPPLGGLEAAHRLGRG
FERLVMLSSLSKRSNVPGMRSGFVAGDAALLKKFLLYRTYHGAALSPVWQHASIAAWNDEAHVRENRALYLQKFNTVTPM
LADVIDVKLPDAAFYLWANVSRTGLSDTEFARRLYADYNVTVLPGSYLARDAHGTNPGRDFIRIALVAGTPECVEGAQRI
VDFCRALAR

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=275, Percent_Identity=25.4545454545455, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI169881279, Length=275, Percent_Identity=25.4545454545455, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI56713256, Length=335, Percent_Identity=23.5820895522388, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI56713254, Length=335, Percent_Identity=23.5820895522388, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1788722, Length=365, Percent_Identity=27.1232876712329, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1787909, Length=409, Percent_Identity=23.7163814180929, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786816, Length=380, Percent_Identity=24.2105263157895, Blast_Score=65, Evalue=8e-12,
Organism=Drosophila melanogaster, GI18859735, Length=412, Percent_Identity=24.0291262135922, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 44621; Mature: 44490

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAASPVNPRLDSLQPYPFEKLRALFKDVTPSGDLKPISFGIGEPKHATPALIRDAVVAAL
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHH
DGLASYPATAGSDALRTSIAHWLERRYGLPAIDPATQVLPVSGSREALFSLAQTVIDARP
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHCCC
SADGKKAIVLCPNPFYQIYEGAALLAGAEPYFANSDPARNFACDYAAVPDDVWARTQLLY
CCCCCEEEEECCCHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHCCEEEEE
VCSPGNPTGAVLTLDDWRELFALSDRHGFVIASDECYSEIYFDEAAPPLGGLEAAHRLGR
EECCCCCCEEEEEHHHHHHHHHHCCCCCEEEECHHHHHHHHHHCCCCCCCHHHHHHHHHH
GFERLVMLSSLSKRSNVPGMRSGFVAGDAALLKKFLLYRTYHGAALSPVWQHASIAAWND
HHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHCCEEEEECC
EAHVRENRALYLQKFNTVTPMLADVIDVKLPDAAFYLWANVSRTGLSDTEFARRLYADYN
CHHHHCCCEEEEHHHCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCC
VTVLPGSYLARDAHGTNPGRDFIRIALVAGTPECVEGAQRIVDFCRALAR
EEEECCHHHHCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AASPVNPRLDSLQPYPFEKLRALFKDVTPSGDLKPISFGIGEPKHATPALIRDAVVAAL
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHH
DGLASYPATAGSDALRTSIAHWLERRYGLPAIDPATQVLPVSGSREALFSLAQTVIDARP
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHCCC
SADGKKAIVLCPNPFYQIYEGAALLAGAEPYFANSDPARNFACDYAAVPDDVWARTQLLY
CCCCCEEEEECCCHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHCCEEEEE
VCSPGNPTGAVLTLDDWRELFALSDRHGFVIASDECYSEIYFDEAAPPLGGLEAAHRLGR
EECCCCCCEEEEEHHHHHHHHHHCCCCCEEEECHHHHHHHHHHCCCCCCCHHHHHHHHHH
GFERLVMLSSLSKRSNVPGMRSGFVAGDAALLKKFLLYRTYHGAALSPVWQHASIAAWND
HHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHCCEEEEECC
EAHVRENRALYLQKFNTVTPMLADVIDVKLPDAAFYLWANVSRTGLSDTEFARRLYADYN
CHHHHCCCEEEEHHHCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCC
VTVLPGSYLARDAHGTNPGRDFIRIALVAGTPECVEGAQRIVDFCRALAR
EEEECCHHHHCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA