Click here to switch to the map view.

The map label for this gene is yaeL [C]

Identifier: 116690033

GI number: 116690033

Start: 2228814

End: 2230187

Strand: Reverse

Name: yaeL [C]

Synonym: Bcen2424_2012

Alternate gene names: 116690033

Gene position: 2230187-2228814 (Counterclockwise)

Preceding gene: 116690034

Following gene: 116690032

Centisome position: 64.01

GC content: 67.25

Gene sequence:

>1374_bases
ATGAACGTGCTGGTCGAACTGGTCGCGTTTGCGGTGGCGATCGGGGTACTGGTCGTCGTGCATGAGTACGGACATTATCG
CGTCGCGCGCTGGTGCGGCGTGAAGGTGCTGCGTTTCTCGATCGGCTTCGGCCAGCCCATCGCGCGCTGGGTCAGCCGCA
GGACGGGCACCGAGTGGACGCTGTCCGTGCTGCCGCTCGGCGGCTACGTGAAGATGCTCGACGAGCGCGATCCGGGCCCG
GGCGGCATCCCGGCCGAAGAGCTCGGCCAGGCATTCAACCGCCAGTCGGTCTACAAGCGCATCGCGATCGTCGCGGCCGG
GCCGATTGCAAACTTCCTGCTGGCAATCGCACTGTTTTCCCTCGTATTCGCCACCGGCGTGACCGAGCCGACCGCGATCG
TCGCGCCGCCGGCCGCCGGCACCGCAGCGGCTCGCGCGGGCTTCGACGGCAGCGAGACGGTCGTGTCGATCCGCAACGCG
CAGGGCGGCGAGTCCGAGCCGGTGCGATCGTGGTCGGACCTGCGCTGGAAGCTGCTGTCGGCCGCGTTCGACCATCGCGA
GGTCGTGCTCGGCGCGCGCGACGGCAATGCGACGTTCGACTTCCGCGTCGACCTCCGCAACGTGCCCGACAGCCAGCTCG
ACGACGACTTCATGGCCCATCTGGGCTTCGAGGCCGGCGGCGGCACGTTGTCGGTCGCGTCGGTGCAGCCGGGCAGCGCG
GCGGAGCAGGCCGGCCTGAAGGTCGGCGACAAGCTGGTCGCGCTCGACGGCAAGCCGATCGGCGGCGCGGCGCGTTTCAT
CGATACGGTGAAGCACCATGCGGGCCAGCCGCTCGAGCTGCGGATCGAGCGCAATGGCGCCGCACAGACGGTGTCGATCG
TGCCGCAGATGCAGCGTGACGACGAATCGGGGCAGCAGATCGGCCGCATCGGCGCGGCGCTGTCGATGCACGCGCCGTCG
GTGGACGTGCGCTACGGGCCGATCGAGAGCCTGCGGCTCGGCGCGCACCGCACGTGGGACATTTCCGTGTATTCGCTGAA
GATGTTCGGGCGGATGATCACGGGCAACGCGTCGCTGAAGAACCTGTCCGGCCCGGTGACGATCGCCGACTACGCAGGCA
AGAGCGCGCGGCTCGGTCCGTCGGCGTTCCTGTCGTTCCTCGCCCTTGTCAGCATTAGCCTTGGCGTCCTGAACTTGTTG
CCGATTCCCGTTTTGGACGGGGGGCATCTGTTATATTATGCGGTTGAAGCCGCGACCGGGAAAGCCGTCTCGGAGCGCTG
GCAGCTGATTCTGCAAAGAGCCGGGTTGATCTGCATCGTCGCGTTGTCGGCGATCGCGCTGTTCAACGATCTGGCTCGGT
TAATCCATTTCTGA

Upstream 100 bases:

>100_bases
ACGTCCTCGCGGCGGATGCCGAGGCTCGCCGCCTCGCCGCCGCGATCATTGCGAAAGCGCCTGCGCCACGCGTGGAGCGT
ACTGTCTGAATGGGGTGCTC

Downstream 100 bases:

>100_bases
AGCGTCAGGCGGCGGCCGCTGGCCAGCCGCCCGATTTGATGCAGCTAAATATTGGGGATGCATGTTGTTCAAACCTCATC
GCTTTGTACCTAAGACAGTT

Product: putative membrane-associated zinc metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MNVLVELVAFAVAIGVLVVVHEYGHYRVARWCGVKVLRFSIGFGQPIARWVSRRTGTEWTLSVLPLGGYVKMLDERDPGP
GGIPAEELGQAFNRQSVYKRIAIVAAGPIANFLLAIALFSLVFATGVTEPTAIVAPPAAGTAAARAGFDGSETVVSIRNA
QGGESEPVRSWSDLRWKLLSAAFDHREVVLGARDGNATFDFRVDLRNVPDSQLDDDFMAHLGFEAGGGTLSVASVQPGSA
AEQAGLKVGDKLVALDGKPIGGAARFIDTVKHHAGQPLELRIERNGAAQTVSIVPQMQRDDESGQQIGRIGAALSMHAPS
VDVRYGPIESLRLGAHRTWDISVYSLKMFGRMITGNASLKNLSGPVTIADYAGKSARLGPSAFLSFLALVSISLGVLNLL
PIPVLDGGHLLYYAVEAATGKAVSERWQLILQRAGLICIVALSAIALFNDLARLIHF

Sequences:

>Translated_457_residues
MNVLVELVAFAVAIGVLVVVHEYGHYRVARWCGVKVLRFSIGFGQPIARWVSRRTGTEWTLSVLPLGGYVKMLDERDPGP
GGIPAEELGQAFNRQSVYKRIAIVAAGPIANFLLAIALFSLVFATGVTEPTAIVAPPAAGTAAARAGFDGSETVVSIRNA
QGGESEPVRSWSDLRWKLLSAAFDHREVVLGARDGNATFDFRVDLRNVPDSQLDDDFMAHLGFEAGGGTLSVASVQPGSA
AEQAGLKVGDKLVALDGKPIGGAARFIDTVKHHAGQPLELRIERNGAAQTVSIVPQMQRDDESGQQIGRIGAALSMHAPS
VDVRYGPIESLRLGAHRTWDISVYSLKMFGRMITGNASLKNLSGPVTIADYAGKSARLGPSAFLSFLALVSISLGVLNLL
PIPVLDGGHLLYYAVEAATGKAVSERWQLILQRAGLICIVALSAIALFNDLARLIHF
>Mature_457_residues
MNVLVELVAFAVAIGVLVVVHEYGHYRVARWCGVKVLRFSIGFGQPIARWVSRRTGTEWTLSVLPLGGYVKMLDERDPGP
GGIPAEELGQAFNRQSVYKRIAIVAAGPIANFLLAIALFSLVFATGVTEPTAIVAPPAAGTAAARAGFDGSETVVSIRNA
QGGESEPVRSWSDLRWKLLSAAFDHREVVLGARDGNATFDFRVDLRNVPDSQLDDDFMAHLGFEAGGGTLSVASVQPGSA
AEQAGLKVGDKLVALDGKPIGGAARFIDTVKHHAGQPLELRIERNGAAQTVSIVPQMQRDDESGQQIGRIGAALSMHAPS
VDVRYGPIESLRLGAHRTWDISVYSLKMFGRMITGNASLKNLSGPVTIADYAGKSARLGPSAFLSFLALVSISLGVLNLL
PIPVLDGGHLLYYAVEAATGKAVSERWQLILQRAGLICIVALSAIALFNDLARLIHF

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=463, Percent_Identity=39.7408207343413, Blast_Score=295, Evalue=5e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 48663; Mature: 48663

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLVELVAFAVAIGVLVVVHEYGHYRVARWCGVKVLRFSIGFGQPIARWVSRRTGTEWT
CHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHCEEEEEEECCCCCHHHHHHHHCCCCCEE
LSVLPLGGYVKMLDERDPGPGGIPAEELGQAFNRQSVYKRIAIVAAGPIANFLLAIALFS
EEEEECCCHHHHHCCCCCCCCCCCHHHHHHHHCHHHHHHHHHEEECCHHHHHHHHHHHHH
LVFATGVTEPTAIVAPPAAGTAAARAGFDGSETVVSIRNAQGGESEPVRSWSDLRWKLLS
HHHHHCCCCCCEEEECCCCCCHHHHCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHH
AAFDHREVVLGARDGNATFDFRVDLRNVPDSQLDDDFMAHLGFEAGGGTLSVASVQPGSA
HHCCCCEEEEEECCCCCEEEEEEEECCCCCCCCCHHHHHHCCCCCCCCEEEEEECCCCCH
AEQAGLKVGDKLVALDGKPIGGAARFIDTVKHHAGQPLELRIERNGAAQTVSIVPQMQRD
HHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCCHHCC
DESGQQIGRIGAALSMHAPSVDVRYGPIESLRLGAHRTWDISVYSLKMFGRMITGNASLK
CHHHHHHHHHHHHHEECCCCCEEEECCHHHHHCCCCCEEEEEEEEHHHHHHHHCCCCCCC
NLSGPVTIADYAGKSARLGPSAFLSFLALVSISLGVLNLLPIPVLDGGHLLYYAVEAATG
CCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCEEEEEEEEHHCC
KAVSERWQLILQRAGLICIVALSAIALFNDLARLIHF
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNVLVELVAFAVAIGVLVVVHEYGHYRVARWCGVKVLRFSIGFGQPIARWVSRRTGTEWT
CHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHCEEEEEEECCCCCHHHHHHHHCCCCCEE
LSVLPLGGYVKMLDERDPGPGGIPAEELGQAFNRQSVYKRIAIVAAGPIANFLLAIALFS
EEEEECCCHHHHHCCCCCCCCCCCHHHHHHHHCHHHHHHHHHEEECCHHHHHHHHHHHHH
LVFATGVTEPTAIVAPPAAGTAAARAGFDGSETVVSIRNAQGGESEPVRSWSDLRWKLLS
HHHHHCCCCCCEEEECCCCCCHHHHCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHH
AAFDHREVVLGARDGNATFDFRVDLRNVPDSQLDDDFMAHLGFEAGGGTLSVASVQPGSA
HHCCCCEEEEEECCCCCEEEEEEEECCCCCCCCCHHHHHHCCCCCCCCEEEEEECCCCCH
AEQAGLKVGDKLVALDGKPIGGAARFIDTVKHHAGQPLELRIERNGAAQTVSIVPQMQRD
HHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCCHHCC
DESGQQIGRIGAALSMHAPSVDVRYGPIESLRLGAHRTWDISVYSLKMFGRMITGNASLK
CHHHHHHHHHHHHHEECCCCCEEEECCHHHHHCCCCCEEEEEEEEHHHHHHHHCCCCCCC
NLSGPVTIADYAGKSARLGPSAFLSFLALVSISLGVLNLLPIPVLDGGHLLYYAVEAATG
CCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCEEEEEEEEHHCC
KAVSERWQLILQRAGLICIVALSAIALFNDLARLIHF
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]