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The map label for this gene is acoC [H]

Identifier: 116689858

GI number: 116689858

Start: 2040935

End: 2042050

Strand: Reverse

Name: acoC [H]

Synonym: Bcen2424_1837

Alternate gene names: 116689858

Gene position: 2042050-2040935 (Counterclockwise)

Preceding gene: 116689859

Following gene: 116689857

Centisome position: 58.61

GC content: 70.52

Gene sequence:

>1116_bases
ATGTCGATTCACATGATCACGATGCCCAAATGGGGGCTGTCGATGGAGCAGGGGCAGGTCAACGGCTGGCTGAAGGCGGT
CGGCGAACGCGTGGCGAAGGGCGACGAAGTGCTCGACGTCGAGACCGACAAGATCTCGTCGGGTGTCGAATGCGCATTCG
ACGGCACGCTGCGCCGGCAGGTCGCGCAGGAGGGCGAGACGCTGCCCGTCGGCGCGCTGCTCGGTGTCGTCGCGGCCGCC
GAGGCGAGCGATGCCGACATCGACGCGGCGATCGCCGATTTCCAGCGCGATTTCGTGCCGAGCGCGGCGTCCGACGAGGC
GGCCGGCCCGCAGCCGGAGAAGGCGCAGATCGGCGGCCGCACGGTCCGCTTCCTGAAGCTGGGCGAGGGGTCGGGCACGC
CCGCCGTGCTGATCCACGGCTTCGGCGGCGACCTGAACAACTGGCTGTTCAACCACGCGGAGCTCGCCGCGCACCGGCCG
GTGTGGGCGCTCGATCTGCCCGGCCACGGCGAATCGGGCAAGGCGGTCGAGACCGGCAGCCTCGACGAACTGGCCGACGC
GGTGCTCGCGCTGCTCGATGCGCAGCACATCGAGCGCGCGCACCTGATCGGCCATTCGATGGGCGGGGCGGTCGCGATGA
CGGTGGCCGAGCGCGCACCGCAACGCGTTGCATCGCTCACGCTGATCGCGAGCGCGGGGCTCGGCACCGACATCAACCGC
GCGTACATCGACGGCTTCGTCGCCGGCAACAGCCGCAACACGCTGAAACCGCACCTCGGCGCGCTGTTCGCGGACGACGC
GCTGGTCACGCGGCAACTCGTCGAGGACCTCGTCAAGTACAAGCGGCTCGAAGGCGTGCAGGCCGCGCTGGAGAAGATCG
CGCACGCCGCGTTCGACGGCGCCGCGCAGCGGCGTGTGTTCCGTGACCGGCTCGCGACGCTGGCGCCGCGCACGCTCGTG
ATCTGGGGCGAGCGCGACCAGGTGATTCCCGCGCAGCATGCGCAGGGCTTGCCGGACGGCGTGCGTGCCGAGGTGATCGC
CGGCAGCGGGCACATGGTGCAGATGGAAGCGGCCGCCGACGTGAACCGCCTGATCGTCGCGTTCCTCGGAGACTGA

Upstream 100 bases:

>100_bases
CCGCATACGCCCGCGCCGTTCGCCGGCGTGCTGGAAGACCTGTATATCCCGTCCGCCGATGCAATTGCGCAGGCGGTACT
CAAGACGAGGAGCTGACACG

Downstream 100 bases:

>100_bases
CGATGACCGCCGCGCTCGAACGACCCAGCCGCACGGCGCTCGGCCAGCCCGGCGCGAGAAGTCGCGACAAGCTCGCGCGC
ATTCCGGTGCGCGTCGAGCC

Product: branched-chain alpha-keto acid dehydrogenase subunit E2

Products: NA

Alternate protein names: Acetoin dehydrogenase E2 component; Dihydrolipoamide acetyltransferase component of acetoin cleaving system [H]

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MSIHMITMPKWGLSMEQGQVNGWLKAVGERVAKGDEVLDVETDKISSGVECAFDGTLRRQVAQEGETLPVGALLGVVAAA
EASDADIDAAIADFQRDFVPSAASDEAAGPQPEKAQIGGRTVRFLKLGEGSGTPAVLIHGFGGDLNNWLFNHAELAAHRP
VWALDLPGHGESGKAVETGSLDELADAVLALLDAQHIERAHLIGHSMGGAVAMTVAERAPQRVASLTLIASAGLGTDINR
AYIDGFVAGNSRNTLKPHLGALFADDALVTRQLVEDLVKYKRLEGVQAALEKIAHAAFDGAAQRRVFRDRLATLAPRTLV
IWGERDQVIPAQHAQGLPDGVRAEVIAGSGHMVQMEAAADVNRLIVAFLGD

Sequences:

>Translated_371_residues
MSIHMITMPKWGLSMEQGQVNGWLKAVGERVAKGDEVLDVETDKISSGVECAFDGTLRRQVAQEGETLPVGALLGVVAAA
EASDADIDAAIADFQRDFVPSAASDEAAGPQPEKAQIGGRTVRFLKLGEGSGTPAVLIHGFGGDLNNWLFNHAELAAHRP
VWALDLPGHGESGKAVETGSLDELADAVLALLDAQHIERAHLIGHSMGGAVAMTVAERAPQRVASLTLIASAGLGTDINR
AYIDGFVAGNSRNTLKPHLGALFADDALVTRQLVEDLVKYKRLEGVQAALEKIAHAAFDGAAQRRVFRDRLATLAPRTLV
IWGERDQVIPAQHAQGLPDGVRAEVIAGSGHMVQMEAAADVNRLIVAFLGD
>Mature_370_residues
SIHMITMPKWGLSMEQGQVNGWLKAVGERVAKGDEVLDVETDKISSGVECAFDGTLRRQVAQEGETLPVGALLGVVAAAE
ASDADIDAAIADFQRDFVPSAASDEAAGPQPEKAQIGGRTVRFLKLGEGSGTPAVLIHGFGGDLNNWLFNHAELAAHRPV
WALDLPGHGESGKAVETGSLDELADAVLALLDAQHIERAHLIGHSMGGAVAMTVAERAPQRVASLTLIASAGLGTDINRA
YIDGFVAGNSRNTLKPHLGALFADDALVTRQLVEDLVKYKRLEGVQAALEKIAHAAFDGAAQRRVFRDRLATLAPRTLVI
WGERDQVIPAQHAQGLPDGVRAEVIAGSGHMVQMEAAADVNRLIVAFLGD

Specific function: 3-hydroxyphenylpropionate degradation. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 lipoyl-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081721, Length=298, Percent_Identity=26.8456375838926, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003016
- InterPro:   IPR000073
- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF00364 Biotin_lipoyl [H]

EC number: =2.3.1.12 [H]

Molecular weight: Translated: 39192; Mature: 39061

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS50968 BIOTINYL_LIPOYL ; PS00189 LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIHMITMPKWGLSMEQGQVNGWLKAVGERVAKGDEVLDVETDKISSGVECAFDGTLRRQ
CEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCHHHCCCCCEEEECHHHHHH
VAQEGETLPVGALLGVVAAAEASDADIDAAIADFQRDFVPSAASDEAAGPQPEKAQIGGR
HHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCC
TVRFLKLGEGSGTPAVLIHGFGGDLNNWLFNHAELAAHRPVWALDLPGHGESGKAVETGS
EEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEECCC
LDELADAVLALLDAQHIERAHLIGHSMGGAVAMTVAERAPQRVASLTLIASAGLGTDINR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCH
AYIDGFVAGNSRNTLKPHLGALFADDALVTRQLVEDLVKYKRLEGVQAALEKIAHAAFDG
HHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAQRRVFRDRLATLAPRTLVIWGERDQVIPAQHAQGLPDGVRAEVIAGSGHMVQMEAAAD
HHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHCCCCCCCEEEEEECCCCEEEEHHHCC
VNRLIVAFLGD
CCCEEEEEECC
>Mature Secondary Structure 
SIHMITMPKWGLSMEQGQVNGWLKAVGERVAKGDEVLDVETDKISSGVECAFDGTLRRQ
EEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCHHHCCCCCEEEECHHHHHH
VAQEGETLPVGALLGVVAAAEASDADIDAAIADFQRDFVPSAASDEAAGPQPEKAQIGGR
HHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCC
TVRFLKLGEGSGTPAVLIHGFGGDLNNWLFNHAELAAHRPVWALDLPGHGESGKAVETGS
EEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEECCC
LDELADAVLALLDAQHIERAHLIGHSMGGAVAMTVAERAPQRVASLTLIASAGLGTDINR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCH
AYIDGFVAGNSRNTLKPHLGALFADDALVTRQLVEDLVKYKRLEGVQAALEKIAHAAFDG
HHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAQRRVFRDRLATLAPRTLVIWGERDQVIPAQHAQGLPDGVRAEVIAGSGHMVQMEAAAD
HHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHCCCCCCCEEEEEECCCCEEEEHHHCC
VNRLIVAFLGD
CCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7813883 [H]