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The map label for this gene is fadH [H]

Identifier: 116689366

GI number: 116689366

Start: 1481986

End: 1484010

Strand: Direct

Name: fadH [H]

Synonym: Bcen2424_1344

Alternate gene names: 116689366

Gene position: 1481986-1484010 (Clockwise)

Preceding gene: 116689364

Following gene: 116689367

Centisome position: 42.54

GC content: 67.8

Gene sequence:

>2025_bases
ATGGCTTCCCGTTATCCGCATTTGACGACCCCGCTCGAACTCGGCTTCACGTCGCTCCGGAACCGCGTGTTGATGGGGTC
GATGCACGTCGGCCTGGAGGAAGCGCCGAACGGTTTCGAGCGGATGGCCGCCTTCTATGCGGAGCGTGCGCGCGGCGAGG
CCGGCCTGATCGTCACGGGCGGCTTCGCGCCGAACGAGCGCGGCCGTCCTGCGCCCGGCGGCGCGATGCTGACGACCGAA
GCGGAAGCCGAACGCCATCGCGTCGTGACGCGTGCAGTGCAGGCCGAGGGCGGCAGGATCGCGTTGCAGATCCTGCATTT
CGGGCGCTACGCGTATCACCCGGCGCTCGCGGCGCCCAGTGCGCTGAAGGCGCCGATCAACCGGTTTACGCCGCATGCGC
TGACGAGCGACGAGGTCGACGAGACGATCGCCGATTTCGTGCGATGCGCGGCGCTCGCGCAGCATGCGGGCTACGACGGC
GTGGAGATCATGGGGTCCGAGGGCTACCTGATCAACGAATTCATCGCCGCACGCACGAACCATCGCGACGATGCGTGGGG
CGGCGCGTACGAGAACCGCATCCGTTTCGCGGTCGAGATCGTGCGGCGGGTGCGCGAGCGTGTCGGCACGAACTTCATCG
TCATCTACCGGCTGTCGATGCTCGATCTCGTCGAAGGCGGCTCGACGCTCGACGAGGTGATCCGGCTCGCGCAGGCGATC
GAGGCGGCGGGCGCGACGATCCTCAATACCGGCATCGGCTGGCACGAGGCGCGCATTCCGACCATCGCGACCAAGGTGCC
GCGCGCCGCGTATGCGTGGGTGACGCGGCAACTGATGGGCAAGGTCGGCATCCCGCTCGTCGCGACCAACCGGATCAACA
CGCCGGAAGTCGCCGAGCAACTGCTCGCCGACGGCTATTGCGACATGGTGTCGATGGCGCGGCCGTTCCTTGCCGATGCC
GAGTTCGTTCGCAAGGCGCGGGAAGGGCGCGCGGACGAAATCAACACGTGCATCGGCTGCAACCAGGCGTGCCTCGACCA
TACGTTCAGCGGCAGGATCACGTCGTGCCTCGTGAATCCGCGTGCGTGTCATGAAACCGAGCTCGTGATCCAGCCCGCGC
CGCAGCGCAAGCGGATCGCGGTGGTCGGCGCCGGGCCGGCGGGCCTCGGCTTCGCGGTCACGGCGGCCGAACGCGGTCAT
GCGGTCACGCTGTACGAAGCGGGCGCCGAGATCGGCGGCCAGTTCAACATCGCGAAGAAGGTGCCCGGCAAGGAAGAGTT
CAACGAGACGCTGCGCTATTTCCGTCGGCAGATCGAATTGCGCGGCATCGCGCTGCACGTCAACACGCGCGCGACCGCCG
AGATGCTGTTGCAGGGCGAATTCGACGAAGTGGTGATCGCGACGGGCATCGTGCCGCGCACGCCGCCGATCGACGGCATC
GGACATCCGAAAGCGCTCGGCTATCTCGACGTGCTGCGCGACGACAAGGCCGTGGGCCGCAGCGTCGCGATCGTCGGCGC
GGGCGGCATCGGCTTCGACGTCGCCGAATATCTCGTTCATCGCGACGCTGGCGAACGTGTCGACGCTGACCGGTTCTTCA
GCGAATGGGGTGTCGACCGGTCGTATGCGAATGCCGGCGGGCTGGGTGTCGCGCGGCCCGAGCCGGCGGCGCGGCACGTA
CATCTGCTGCAGCGCAAGGCGTCGAAGGTCGGCGACGGGCTCGGCAAGACCACCGGATGGATTCACCGTACGGCGCTGAA
GGCGCGCGGCGTCGGGATGTCGTCGGCGGTCACGTACCGGCGCATCGACGATGAAGGTCTTCACGTGACGATCGACGGCG
TCGAGCAGATGCTGCCGGTGGACAACGTGGTGATCTGCGCGGGGCAGGAGCCGTCGCGCGAGCTGGCGGAGCAACTGCAG
GCAGCCGGATGCCGCGTGCATCTGATCGGCGGCGCATGCGAGGCCGCCGAACTCGATGCGAAGCGCGCGATTCACCAGGG
CACGACGCTGGCCGCGACCCTTTGA

Upstream 100 bases:

>100_bases
GCAGCACAAACGACGCGGGTGCTTTTATGCAACATGTTGCACAAACAAAGCCGACGAGCTACCATCAATGCAACTTGTTG
CATAAACATGGAGACACCCG

Downstream 100 bases:

>100_bases
TACCGATTCGTTTCTTCCCCCGTCCAACCACGTTACTGGAGACTGCGATGACGCACTCGCCGCTGAATGTTCATCCCGCC
GTCGCGAAATCGCTCGACGC

Product: NADH:flavin oxidoreductase/NADH oxidase

Products: NA

Alternate protein names: 2,4-dienoyl coenzyme A reductase [H]

Number of amino acids: Translated: 674; Mature: 673

Protein sequence:

>674_residues
MASRYPHLTTPLELGFTSLRNRVLMGSMHVGLEEAPNGFERMAAFYAERARGEAGLIVTGGFAPNERGRPAPGGAMLTTE
AEAERHRVVTRAVQAEGGRIALQILHFGRYAYHPALAAPSALKAPINRFTPHALTSDEVDETIADFVRCAALAQHAGYDG
VEIMGSEGYLINEFIAARTNHRDDAWGGAYENRIRFAVEIVRRVRERVGTNFIVIYRLSMLDLVEGGSTLDEVIRLAQAI
EAAGATILNTGIGWHEARIPTIATKVPRAAYAWVTRQLMGKVGIPLVATNRINTPEVAEQLLADGYCDMVSMARPFLADA
EFVRKAREGRADEINTCIGCNQACLDHTFSGRITSCLVNPRACHETELVIQPAPQRKRIAVVGAGPAGLGFAVTAAERGH
AVTLYEAGAEIGGQFNIAKKVPGKEEFNETLRYFRRQIELRGIALHVNTRATAEMLLQGEFDEVVIATGIVPRTPPIDGI
GHPKALGYLDVLRDDKAVGRSVAIVGAGGIGFDVAEYLVHRDAGERVDADRFFSEWGVDRSYANAGGLGVARPEPAARHV
HLLQRKASKVGDGLGKTTGWIHRTALKARGVGMSSAVTYRRIDDEGLHVTIDGVEQMLPVDNVVICAGQEPSRELAEQLQ
AAGCRVHLIGGACEAAELDAKRAIHQGTTLAATL

Sequences:

>Translated_674_residues
MASRYPHLTTPLELGFTSLRNRVLMGSMHVGLEEAPNGFERMAAFYAERARGEAGLIVTGGFAPNERGRPAPGGAMLTTE
AEAERHRVVTRAVQAEGGRIALQILHFGRYAYHPALAAPSALKAPINRFTPHALTSDEVDETIADFVRCAALAQHAGYDG
VEIMGSEGYLINEFIAARTNHRDDAWGGAYENRIRFAVEIVRRVRERVGTNFIVIYRLSMLDLVEGGSTLDEVIRLAQAI
EAAGATILNTGIGWHEARIPTIATKVPRAAYAWVTRQLMGKVGIPLVATNRINTPEVAEQLLADGYCDMVSMARPFLADA
EFVRKAREGRADEINTCIGCNQACLDHTFSGRITSCLVNPRACHETELVIQPAPQRKRIAVVGAGPAGLGFAVTAAERGH
AVTLYEAGAEIGGQFNIAKKVPGKEEFNETLRYFRRQIELRGIALHVNTRATAEMLLQGEFDEVVIATGIVPRTPPIDGI
GHPKALGYLDVLRDDKAVGRSVAIVGAGGIGFDVAEYLVHRDAGERVDADRFFSEWGVDRSYANAGGLGVARPEPAARHV
HLLQRKASKVGDGLGKTTGWIHRTALKARGVGMSSAVTYRRIDDEGLHVTIDGVEQMLPVDNVVICAGQEPSRELAEQLQ
AAGCRVHLIGGACEAAELDAKRAIHQGTTLAATL
>Mature_673_residues
ASRYPHLTTPLELGFTSLRNRVLMGSMHVGLEEAPNGFERMAAFYAERARGEAGLIVTGGFAPNERGRPAPGGAMLTTEA
EAERHRVVTRAVQAEGGRIALQILHFGRYAYHPALAAPSALKAPINRFTPHALTSDEVDETIADFVRCAALAQHAGYDGV
EIMGSEGYLINEFIAARTNHRDDAWGGAYENRIRFAVEIVRRVRERVGTNFIVIYRLSMLDLVEGGSTLDEVIRLAQAIE
AAGATILNTGIGWHEARIPTIATKVPRAAYAWVTRQLMGKVGIPLVATNRINTPEVAEQLLADGYCDMVSMARPFLADAE
FVRKAREGRADEINTCIGCNQACLDHTFSGRITSCLVNPRACHETELVIQPAPQRKRIAVVGAGPAGLGFAVTAAERGHA
VTLYEAGAEIGGQFNIAKKVPGKEEFNETLRYFRRQIELRGIALHVNTRATAEMLLQGEFDEVVIATGIVPRTPPIDGIG
HPKALGYLDVLRDDKAVGRSVAIVGAGGIGFDVAEYLVHRDAGERVDADRFFSEWGVDRSYANAGGLGVARPEPAARHVH
LLQRKASKVGDGLGKTTGWIHRTALKARGVGMSSAVTYRRIDDEGLHVTIDGVEQMLPVDNVVICAGQEPSRELAEQLQA
AGCRVHLIGGACEAAELDAKRAIHQGTTLAATL

Specific function: Catalyzes the NADP-dependent reduction of 2,4-dienoyl- CoA to yield trans-2- enoyl-CoA [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789463, Length=670, Percent_Identity=65.2238805970149, Blast_Score=889, Evalue=0.0,
Organism=Escherichia coli, GI1787939, Length=352, Percent_Identity=28.125, Blast_Score=99, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17559802, Length=317, Percent_Identity=25.5520504731861, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17564188, Length=308, Percent_Identity=24.025974025974, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17540738, Length=220, Percent_Identity=26.8181818181818, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17559804, Length=368, Percent_Identity=24.7282608695652, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17565138, Length=227, Percent_Identity=28.6343612334802, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17566914, Length=313, Percent_Identity=25.8785942492013, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI72001454, Length=216, Percent_Identity=26.8518518518519, Blast_Score=82, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6321973, Length=225, Percent_Identity=27.1111111111111, Blast_Score=84, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6325086, Length=235, Percent_Identity=28.5106382978723, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF07992 Pyr_redox_2 [H]

EC number: =1.3.1.34 [H]

Molecular weight: Translated: 72755; Mature: 72624

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASRYPHLTTPLELGFTSLRNRVLMGSMHVGLEEAPNGFERMAAFYAERARGEAGLIVTG
CCCCCCCCCCHHHHHHHHHHCCEEECHHHCCHHHCCCHHHHHHHHHHHHHCCCCCEEEEC
GFAPNERGRPAPGGAMLTTEAEAERHRVVTRAVQAEGGRIALQILHFGRYAYHPALAAPS
CCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHCHHHCCCH
ALKAPINRFTPHALTSDEVDETIADFVRCAALAQHAGYDGVEIMGSEGYLINEFIAARTN
HHHCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHCC
HRDDAWGGAYENRIRFAVEIVRRVRERVGTNFIVIYRLSMLDLVEGGSTLDEVIRLAQAI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHCCCCHHHHHHHHHHHH
EAAGATILNTGIGWHEARIPTIATKVPRAAYAWVTRQLMGKVGIPLVATNRINTPEVAEQ
HHCCCEEEECCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHH
LLADGYCDMVSMARPFLADAEFVRKAREGRADEINTCIGCNQACLDHTFSGRITSCLVNP
HHHCCHHHHHHHHCHHHCCHHHHHHHHCCCCHHHHHHHCCCHHHHCCCCCCCHHHEEECC
RACHETELVIQPAPQRKRIAVVGAGPAGLGFAVTAAERGHAVTLYEAGAEIGGQFNIAKK
CCCCCCEEEEECCCCCCEEEEEECCCCCCCEEEEECCCCCEEEEEECCHHCCCCEEECCC
VPGKEEFNETLRYFRRQIELRGIALHVNTRATAEMLLQGEFDEVVIATGIVPRTPPIDGI
CCCHHHHHHHHHHHHHHHEEEEEEEEECCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCC
GHPKALGYLDVLRDDKAVGRSVAIVGAGGIGFDVAEYLVHRDAGERVDADRFFSEWGVDR
CCCHHHHHHHHHHCCHHCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCC
SYANAGGLGVARPEPAARHVHLLQRKASKVGDGLGKTTGWIHRTALKARGVGMSSAVTYR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHCEEEE
RIDDEGLHVTIDGVEQMLPVDNVVICAGQEPSRELAEQLQAAGCRVHLIGGACEAAELDA
EECCCCCEEEECCHHHHCCCCCEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHH
KRAIHQGTTLAATL
HHHHHCCCEEEEEC
>Mature Secondary Structure 
ASRYPHLTTPLELGFTSLRNRVLMGSMHVGLEEAPNGFERMAAFYAERARGEAGLIVTG
CCCCCCCCCHHHHHHHHHHCCEEECHHHCCHHHCCCHHHHHHHHHHHHHCCCCCEEEEC
GFAPNERGRPAPGGAMLTTEAEAERHRVVTRAVQAEGGRIALQILHFGRYAYHPALAAPS
CCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHCHHHCCCH
ALKAPINRFTPHALTSDEVDETIADFVRCAALAQHAGYDGVEIMGSEGYLINEFIAARTN
HHHCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHCC
HRDDAWGGAYENRIRFAVEIVRRVRERVGTNFIVIYRLSMLDLVEGGSTLDEVIRLAQAI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHCCCCHHHHHHHHHHHH
EAAGATILNTGIGWHEARIPTIATKVPRAAYAWVTRQLMGKVGIPLVATNRINTPEVAEQ
HHCCCEEEECCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHH
LLADGYCDMVSMARPFLADAEFVRKAREGRADEINTCIGCNQACLDHTFSGRITSCLVNP
HHHCCHHHHHHHHCHHHCCHHHHHHHHCCCCHHHHHHHCCCHHHHCCCCCCCHHHEEECC
RACHETELVIQPAPQRKRIAVVGAGPAGLGFAVTAAERGHAVTLYEAGAEIGGQFNIAKK
CCCCCCEEEEECCCCCCEEEEEECCCCCCCEEEEECCCCCEEEEEECCHHCCCCEEECCC
VPGKEEFNETLRYFRRQIELRGIALHVNTRATAEMLLQGEFDEVVIATGIVPRTPPIDGI
CCCHHHHHHHHHHHHHHHEEEEEEEEECCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCC
GHPKALGYLDVLRDDKAVGRSVAIVGAGGIGFDVAEYLVHRDAGERVDADRFFSEWGVDR
CCCHHHHHHHHHHCCHHCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCC
SYANAGGLGVARPEPAARHVHLLQRKASKVGDGLGKTTGWIHRTALKARGVGMSSAVTYR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHCEEEE
RIDDEGLHVTIDGVEQMLPVDNVVICAGQEPSRELAEQLQAAGCRVHLIGGACEAAELDA
EECCCCCEEEECCHHHHCCCCCEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHH
KRAIHQGTTLAATL
HHHHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9346310; 9278503 [H]