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The map label for this gene is pdxY [H]

Identifier: 116689189

GI number: 116689189

Start: 1281065

End: 1281925

Strand: Reverse

Name: pdxY [H]

Synonym: Bcen2424_1167

Alternate gene names: 116689189

Gene position: 1281925-1281065 (Counterclockwise)

Preceding gene: 116689191

Following gene: 116689188

Centisome position: 36.8

GC content: 68.76

Gene sequence:

>861_bases
ATGAAAAACGTCCTCAGCATTCAGTCGCACGTCATCTACGGCCATGCCGGCAACAGCGCGGCCGTGTTCCCGATGCAGCG
TCTCGGCATCAACGTCTGGCCGCTCAACACCGTCCAGTTGTCGAATCACATGCAGTACGGCCACTGGGCCGGCAGCGCGA
TCGACGCCGCGAAGATGGAACAGCTCGTCGACGGCATCGCCGCCATCGGCGTGCTCAAGCGGTGCGACGCGGTGCTGTCC
GGCTTCCTCGGCTCGCCGCCGCAGGCACGCGCGGCGGTCGAGATCGTGCGCACGGTGAAAGCGATGAATCCGAACGCGTG
GTACTTCTGCGATCCGGCGATGGGCCAGACGGGCGGCATCCGGCCCGAGCCCGGCGTCGAGGAATTCATCGTGGAGGAGG
TGCCCGCGCTCGCGGACGGCATGTCGCCGAACCACACCGAACTGCAGAAGCTCGCCGGGCGGCGCATCGAGACCGTCGCC
GAAGCCGTCGACGCATGCCGTGCGCTGATCCGCCGCGGCCCGCAGATCATCCTCGTCAAGCACCTGCACGACCGCAACAG
TCCGGCCGACCGTTTCAACATGCTCGCCGTCACCGAGACCGAAGCGTGGATCGGCCAGCGGCCGCTGTATGCGTTTCCGC
GCCACCCGGTCGGCGTCGGCGACCTGACCAGCGCGATCTTCGTCGCGTGCCGGCTGCGCGGCGACTCGGTGCGCGCCGCG
TTCGAGCACACGCTCGCGGCCGTGCACGCGGTGGTGAAGGCCACCTACGACGCGCGCCGCTACGAGCTCGAACTCGTCGC
CGCGCAGGACGAGATCGCCCGCCCGAGCGAATGGTTCGGCGCGTGGGTGACCGACGCCTGA

Upstream 100 bases:

>100_bases
GACGACGGCGCGCAACACTCCGGGGCCACGCGACTTCCGCGCGGTTGACGAACTCGGGTATCGTGTGACGTGACCCTGAA
ACGCGTGCAGGCGAATTCCC

Downstream 100 bases:

>100_bases
CGCGTCGGCACTGCCCTGCGCTGCTCCAGCGCGCCGCTGTCCCGCTGTCCCGCTGTCCCGCTTTCCCGCTTTCCCGCTTT
CCCGTTGCAGCCGACCTGCT

Product: pyridoxal kinase

Products: NA

Alternate protein names: PM kinase [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MKNVLSIQSHVIYGHAGNSAAVFPMQRLGINVWPLNTVQLSNHMQYGHWAGSAIDAAKMEQLVDGIAAIGVLKRCDAVLS
GFLGSPPQARAAVEIVRTVKAMNPNAWYFCDPAMGQTGGIRPEPGVEEFIVEEVPALADGMSPNHTELQKLAGRRIETVA
EAVDACRALIRRGPQIILVKHLHDRNSPADRFNMLAVTETEAWIGQRPLYAFPRHPVGVGDLTSAIFVACRLRGDSVRAA
FEHTLAAVHAVVKATYDARRYELELVAAQDEIARPSEWFGAWVTDA

Sequences:

>Translated_286_residues
MKNVLSIQSHVIYGHAGNSAAVFPMQRLGINVWPLNTVQLSNHMQYGHWAGSAIDAAKMEQLVDGIAAIGVLKRCDAVLS
GFLGSPPQARAAVEIVRTVKAMNPNAWYFCDPAMGQTGGIRPEPGVEEFIVEEVPALADGMSPNHTELQKLAGRRIETVA
EAVDACRALIRRGPQIILVKHLHDRNSPADRFNMLAVTETEAWIGQRPLYAFPRHPVGVGDLTSAIFVACRLRGDSVRAA
FEHTLAAVHAVVKATYDARRYELELVAAQDEIARPSEWFGAWVTDA
>Mature_286_residues
MKNVLSIQSHVIYGHAGNSAAVFPMQRLGINVWPLNTVQLSNHMQYGHWAGSAIDAAKMEQLVDGIAAIGVLKRCDAVLS
GFLGSPPQARAAVEIVRTVKAMNPNAWYFCDPAMGQTGGIRPEPGVEEFIVEEVPALADGMSPNHTELQKLAGRRIETVA
EAVDACRALIRRGPQIILVKHLHDRNSPADRFNMLAVTETEAWIGQRPLYAFPRHPVGVGDLTSAIFVACRLRGDSVRAA
FEHTLAAVHAVVKATYDARRYELELVAAQDEIARPSEWFGAWVTDA

Specific function: Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxamine [H]

COG id: COG2240

COG function: function code H; Pyridoxal/pyridoxine/pyridoxamine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxine kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505701, Length=267, Percent_Identity=31.4606741573034, Blast_Score=125, Evalue=3e-29,
Organism=Escherichia coli, GI1787924, Length=283, Percent_Identity=53.0035335689046, Blast_Score=284, Evalue=4e-78,
Organism=Escherichia coli, GI1788758, Length=264, Percent_Identity=24.6212121212121, Blast_Score=85, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17507759, Length=260, Percent_Identity=30, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17507757, Length=270, Percent_Identity=28.8888888888889, Blast_Score=110, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6324354, Length=273, Percent_Identity=32.2344322344322, Blast_Score=104, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6320806, Length=275, Percent_Identity=30.5454545454545, Blast_Score=93, Evalue=4e-20,
Organism=Drosophila melanogaster, GI45553007, Length=292, Percent_Identity=29.1095890410959, Blast_Score=132, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013749
- InterPro:   IPR004625 [H]

Pfam domain/function: PF08543 Phos_pyr_kin [H]

EC number: =2.7.1.35 [H]

Molecular weight: Translated: 31222; Mature: 31222

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNVLSIQSHVIYGHAGNSAAVFPMQRLGINVWPLNTVQLSNHMQYGHWAGSAIDAAKME
CCCHHEEHHEEEEEECCCCEEECCHHHHCEEECCCCEEECCCCCCCCCCCCCHHHHHHHH
QLVDGIAAIGVLKRCDAVLSGFLGSPPQARAAVEIVRTVKAMNPNAWYFCDPAMGQTGGI
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCC
RPEPGVEEFIVEEVPALADGMSPNHTELQKLAGRRIETVAEAVDACRALIRRGPQIILVK
CCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCEEEEE
HLHDRNSPADRFNMLAVTETEAWIGQRPLYAFPRHPVGVGDLTSAIFVACRLRGDSVRAA
ECCCCCCCHHHHEEEEEECCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHH
FEHTLAAVHAVVKATYDARRYELELVAAQDEIARPSEWFGAWVTDA
HHHHHHHHHHHHHHHHCCHHEEEEEEECCHHHCCCHHHHCEECCCC
>Mature Secondary Structure
MKNVLSIQSHVIYGHAGNSAAVFPMQRLGINVWPLNTVQLSNHMQYGHWAGSAIDAAKME
CCCHHEEHHEEEEEECCCCEEECCHHHHCEEECCCCEEECCCCCCCCCCCCCHHHHHHHH
QLVDGIAAIGVLKRCDAVLSGFLGSPPQARAAVEIVRTVKAMNPNAWYFCDPAMGQTGGI
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCC
RPEPGVEEFIVEEVPALADGMSPNHTELQKLAGRRIETVAEAVDACRALIRRGPQIILVK
CCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCEEEEE
HLHDRNSPADRFNMLAVTETEAWIGQRPLYAFPRHPVGVGDLTSAIFVACRLRGDSVRAA
ECCCCCCCHHHHEEEEEECCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHH
FEHTLAAVHAVVKATYDARRYELELVAAQDEIARPSEWFGAWVTDA
HHHHHHHHHHHHHHHHCCHHEEEEEEECCHHHCCCHHHHCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA