Click here to switch to the map view.

The map label for this gene is map [H]

Identifier: 116689171

GI number: 116689171

Start: 1260742

End: 1261548

Strand: Direct

Name: map [H]

Synonym: Bcen2424_1149

Alternate gene names: 116689171

Gene position: 1260742-1261548 (Clockwise)

Preceding gene: 116689170

Following gene: 116689174

Centisome position: 36.19

GC content: 67.04

Gene sequence:

>807_bases
ATGGCGAAACGAGAAATCCCGATCCGCGGTGCTGCGGAAATCGCCAAGTCGCGCGAAGCCGCGAAGCTCGCGTCGCAGGT
GCTCACAATGATCACCGAGCACGTGAAGCCGGGCGTCACCACCGACGAGCTGGACGCGCGCTGCCGCGAATACATCACCG
ATGAACTCGGCGCGATCCCCGCGAACATCGGCTATCACGGCTATCCGAAGACGCTGTGCACGTCGGTCAATCACGTGGTC
TGTCATGGCATTCCGACGTCGCGGCCGCTGCGCGACGGCGACATCGTGAACCTCGACATCGCGGTGATCAAGGACGGCTG
GTTCGGCGATACGAGCCGGATGTATTTCGTCGGCGAACCGAGCGAACTCGCGCGGCGGCTCGTCGCGGCGACCTACGAGG
CGATGCACGCCGGCATCCGCGCGGTGCGTCCCGGCGCGACGCTCGGCGACGTCGGCTATGCGATCCAGCAGGTCGCGCAT
CGCGAAGGGTTCAGTGTGGTGCGCGAGTATTGCGGGCACGGCATCGGCGACGTCTATCACGACGAGCCGCAGGTGCTGCA
CTACGGTCGCCCGGGCACCGGCCTGCCGCTGCGGCCGGGGATGATCTTCACGATCGAGCCGATGCTGAACGCGGGCAAGC
GCGATACGCGCGTGCTGGCCGACGGCTGGACGGTCGTGACGGCAGACCATTCGCTGTCCGCGCAATGGGAGCACATGGTC
GTGGTGACGGAAACCGGCTTCGAGGTGCTGACCGAGGACGCGAAGCCGCAGGCGTTCGCGGCGCTGTCGGGCACGCACGC
GGCCTGA

Upstream 100 bases:

>100_bases
CCTACGGCGACATCTGCAAGATGCTGATCGAGGCCGAGGCGCGGGGCGGCGACGTGGGGCCGGCGGAGACGGCCGCGCAT
AGCATCGAGCAGGTGGCGTG

Downstream 100 bases:

>100_bases
TGCCGGCGGTGCGCCGCGCGCGGCGGCGCGGCGTTGCAATGAAACGGGCCCCTTCGCGGGGCCCGTGCCGTTTGCGGCGG
CCGGCGCCGCGAACGACACG

Product: methionine aminopeptidase, type I

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MAKREIPIRGAAEIAKSREAAKLASQVLTMITEHVKPGVTTDELDARCREYITDELGAIPANIGYHGYPKTLCTSVNHVV
CHGIPTSRPLRDGDIVNLDIAVIKDGWFGDTSRMYFVGEPSELARRLVAATYEAMHAGIRAVRPGATLGDVGYAIQQVAH
REGFSVVREYCGHGIGDVYHDEPQVLHYGRPGTGLPLRPGMIFTIEPMLNAGKRDTRVLADGWTVVTADHSLSAQWEHMV
VVTETGFEVLTEDAKPQAFAALSGTHAA

Sequences:

>Translated_268_residues
MAKREIPIRGAAEIAKSREAAKLASQVLTMITEHVKPGVTTDELDARCREYITDELGAIPANIGYHGYPKTLCTSVNHVV
CHGIPTSRPLRDGDIVNLDIAVIKDGWFGDTSRMYFVGEPSELARRLVAATYEAMHAGIRAVRPGATLGDVGYAIQQVAH
REGFSVVREYCGHGIGDVYHDEPQVLHYGRPGTGLPLRPGMIFTIEPMLNAGKRDTRVLADGWTVVTADHSLSAQWEHMV
VVTETGFEVLTEDAKPQAFAALSGTHAA
>Mature_267_residues
AKREIPIRGAAEIAKSREAAKLASQVLTMITEHVKPGVTTDELDARCREYITDELGAIPANIGYHGYPKTLCTSVNHVVC
HGIPTSRPLRDGDIVNLDIAVIKDGWFGDTSRMYFVGEPSELARRLVAATYEAMHAGIRAVRPGATLGDVGYAIQQVAHR
EGFSVVREYCGHGIGDVYHDEPQVLHYGRPGTGLPLRPGMIFTIEPMLNAGKRDTRVLADGWTVVTADHSLSAQWEHMVV
VTETGFEVLTEDAKPQAFAALSGTHAA

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=261, Percent_Identity=41.7624521072797, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI40385867, Length=248, Percent_Identity=41.1290322580645, Blast_Score=207, Evalue=1e-53,
Organism=Escherichia coli, GI1786364, Length=247, Percent_Identity=55.8704453441296, Blast_Score=296, Evalue=8e-82,
Organism=Escherichia coli, GI1789275, Length=285, Percent_Identity=25.9649122807018, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71996291, Length=252, Percent_Identity=40.0793650793651, Blast_Score=193, Evalue=6e-50,
Organism=Saccharomyces cerevisiae, GI6323273, Length=256, Percent_Identity=42.1875, Blast_Score=215, Evalue=6e-57,
Organism=Drosophila melanogaster, GI21355531, Length=248, Percent_Identity=43.5483870967742, Blast_Score=210, Evalue=9e-55,
Organism=Drosophila melanogaster, GI24583427, Length=246, Percent_Identity=39.0243902439024, Blast_Score=190, Evalue=7e-49,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 29112; Mature: 28981

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKREIPIRGAAEIAKSREAAKLASQVLTMITEHVKPGVTTDELDARCREYITDELGAIP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCC
ANIGYHGYPKTLCTSVNHVVCHGIPTSRPLRDGDIVNLDIAVIKDGWFGDTSRMYFVGEP
CCCCCCCCCHHHHHCCCCEEEECCCCCCCCCCCCEEEEEEEEEECCCCCCCCEEEEEECH
SELARRLVAATYEAMHAGIRAVRPGATLGDVGYAIQQVAHREGFSVVREYCGHGIGDVYH
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCC
DEPQVLHYGRPGTGLPLRPGMIFTIEPMLNAGKRDTRVLADGWTVVTADHSLSAQWEHMV
CCCCEEEECCCCCCCCCCCCEEEEEEHHHCCCCCCCEEEECCEEEEEECCCCCCCEEEEE
VVTETGFEVLTEDAKPQAFAALSGTHAA
EEEECCHHHHHCCCCCCEEEECCCCCCC
>Mature Secondary Structure 
AKREIPIRGAAEIAKSREAAKLASQVLTMITEHVKPGVTTDELDARCREYITDELGAIP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCC
ANIGYHGYPKTLCTSVNHVVCHGIPTSRPLRDGDIVNLDIAVIKDGWFGDTSRMYFVGEP
CCCCCCCCCHHHHHCCCCEEEECCCCCCCCCCCCEEEEEEEEEECCCCCCCCEEEEEECH
SELARRLVAATYEAMHAGIRAVRPGATLGDVGYAIQQVAHREGFSVVREYCGHGIGDVYH
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCC
DEPQVLHYGRPGTGLPLRPGMIFTIEPMLNAGKRDTRVLADGWTVVTADHSLSAQWEHMV
CCCCEEEECCCCCCCCCCCCEEEEEEHHHCCCCCCCEEEECCEEEEEECCCCCCCEEEEE
VVTETGFEVLTEDAKPQAFAALSGTHAA
EEEECCHHHHHCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]