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The map label for this gene is pncB [H]

Identifier: 116689123

GI number: 116689123

Start: 1211375

End: 1212574

Strand: Direct

Name: pncB [H]

Synonym: Bcen2424_1100

Alternate gene names: 116689123

Gene position: 1211375-1212574 (Clockwise)

Preceding gene: 116689116

Following gene: 116689124

Centisome position: 34.77

GC content: 63.5

Gene sequence:

>1200_bases
ATGATCATCACTTCGCTGCTCGACACGGATCTCTACAAGTTCACGATGATGCAGGTCGTCCTGCATCACTTCCCGGCTGC
AAACGTCGAATACCGCTTCCGGTGCCGCACGCCCGGCGTCGATCTCGTGCCGTACATCGACGAGATTCGCGACGAGGTGC
GCGGCCTGTGCTCGCTGCGCTTTGCCGACGTCGAACTCGACTACCTGCGGCGGATGCGCTTCATCAAGAGCGACTTCGTC
GACTTCCTCGCGCTGTTCCACCTGAACGAGAAGTACATCTCGATCACGCCGTCGCCGAAGGGCAACGGCGAAATCGACAT
CGTGATCGAGGGGCCGTGGCTGCATACGATCCTGTTCGAGATCCCGGTGCTCGCGATCGTCAACGAAGTCTATTTCCGCA
ACACGCAGCGCGAGCCCGACTATCGCGAAGGGCGCGAGCGGCTGCGCGAGAAGATCAAGCTGCTCGGCGCGAAGCCCGAA
TTCGCCGACTGCAAGATCGCCGACTACGGCACGCGCCGGCGCTTCTCGAAGGTCTGGCACGAGGAAGTCGCGCTCACGCT
GCGTGACGGGCTCGGCCCGCAGTTCGCGGGCACGAGCAACGTGCTGTACGCGATGAAGCACGACATCACGCCGCTCGGCA
CGATGGCGCACGAATACCTGCAGGCGTGCCAGGCGCTCGGCCCGCGGCTGCGCGACTCGCAGATCTACGGCTTCGAGATG
TGGGCGAAGGAATATCGCGGCGACCTCGGGATCGCGCTGTCGGACGTCTACGGGATGGACGCGTTCCTGAACGACTTCGA
CATGTACTTCTGCAAACTGTTCGACGGTGCGCGCCACGATTCGGGCGATCCGTTCGAGTGGGGCGAGCGGATGCTGCGCC
ATTACGAGGCGAACCGGTGCGACCCGCGCACCAAGGTGCTCGTGTTCTCGGACGCGCTCGACATCCCGAAGGTCATGCAG
CTGTACGAACGGTTCCGCGGCCGCTGCAAGCTCGCGTTCGGCGTCGGCACCAACCTCACCAACGATCTCGGCTACGTGCC
GCTGCAGATCGTGATCAAGATGGTTCGCTGCAACGGCCAGCCGGTCGCGAAGCTGTCCGATTCGCCGGGCAAGAGCATGT
GCGACGACAAGGCGTATCTCGCGTACCTGCGGCAGGTGTTCGGCATCGCGCAGCCGGTCGACGAAGACGCGTCGAAGTAG

Upstream 100 bases:

>100_bases
GTTTCACGATGGTCCGGCCCGCATTCGGGTAACATGACCGACAGACCGGGCGGCGCGCGGTGCGCCGGGGCCCGGTCACG
ATATTGGCGCTGCCGTCATC

Downstream 100 bases:

>100_bases
GCGTCGGCCGTTCGGCCGAAGGTGTGTCGCGGCAGGGGTGGCCGGTATAATCCGACGTATTGCACGCCAACGTCACGAGG
ACCGTTCATGGACACTTCCG

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MIITSLLDTDLYKFTMMQVVLHHFPAANVEYRFRCRTPGVDLVPYIDEIRDEVRGLCSLRFADVELDYLRRMRFIKSDFV
DFLALFHLNEKYISITPSPKGNGEIDIVIEGPWLHTILFEIPVLAIVNEVYFRNTQREPDYREGRERLREKIKLLGAKPE
FADCKIADYGTRRRFSKVWHEEVALTLRDGLGPQFAGTSNVLYAMKHDITPLGTMAHEYLQACQALGPRLRDSQIYGFEM
WAKEYRGDLGIALSDVYGMDAFLNDFDMYFCKLFDGARHDSGDPFEWGERMLRHYEANRCDPRTKVLVFSDALDIPKVMQ
LYERFRGRCKLAFGVGTNLTNDLGYVPLQIVIKMVRCNGQPVAKLSDSPGKSMCDDKAYLAYLRQVFGIAQPVDEDASK

Sequences:

>Translated_399_residues
MIITSLLDTDLYKFTMMQVVLHHFPAANVEYRFRCRTPGVDLVPYIDEIRDEVRGLCSLRFADVELDYLRRMRFIKSDFV
DFLALFHLNEKYISITPSPKGNGEIDIVIEGPWLHTILFEIPVLAIVNEVYFRNTQREPDYREGRERLREKIKLLGAKPE
FADCKIADYGTRRRFSKVWHEEVALTLRDGLGPQFAGTSNVLYAMKHDITPLGTMAHEYLQACQALGPRLRDSQIYGFEM
WAKEYRGDLGIALSDVYGMDAFLNDFDMYFCKLFDGARHDSGDPFEWGERMLRHYEANRCDPRTKVLVFSDALDIPKVMQ
LYERFRGRCKLAFGVGTNLTNDLGYVPLQIVIKMVRCNGQPVAKLSDSPGKSMCDDKAYLAYLRQVFGIAQPVDEDASK
>Mature_399_residues
MIITSLLDTDLYKFTMMQVVLHHFPAANVEYRFRCRTPGVDLVPYIDEIRDEVRGLCSLRFADVELDYLRRMRFIKSDFV
DFLALFHLNEKYISITPSPKGNGEIDIVIEGPWLHTILFEIPVLAIVNEVYFRNTQREPDYREGRERLREKIKLLGAKPE
FADCKIADYGTRRRFSKVWHEEVALTLRDGLGPQFAGTSNVLYAMKHDITPLGTMAHEYLQACQALGPRLRDSQIYGFEM
WAKEYRGDLGIALSDVYGMDAFLNDFDMYFCKLFDGARHDSGDPFEWGERMLRHYEANRCDPRTKVLVFSDALDIPKVMQ
LYERFRGRCKLAFGVGTNLTNDLGYVPLQIVIKMVRCNGQPVAKLSDSPGKSMCDDKAYLAYLRQVFGIAQPVDEDASK

Specific function: NAD biosynthesis; nicotinamide to NaMN; second step. [C]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

Organism=Escherichia coli, GI1787162, Length=393, Percent_Identity=43.5114503816794, Blast_Score=326, Evalue=2e-90,
Organism=Saccharomyces cerevisiae, GI6324783, Length=401, Percent_Identity=29.426433915212, Blast_Score=190, Evalue=3e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006406
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 46003; Mature: 46003

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIITSLLDTDLYKFTMMQVVLHHFPAANVEYRFRCRTPGVDLVPYIDEIRDEVRGLCSLR
CEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
FADVELDYLRRMRFIKSDFVDFLALFHLNEKYISITPSPKGNGEIDIVIEGPWLHTILFE
EECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEEECCHHHHHHHH
IPVLAIVNEVYFRNTQREPDYREGRERLREKIKLLGAKPEFADCKIADYGTRRRFSKVWH
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHH
EEVALTLRDGLGPQFAGTSNVLYAMKHDITPLGTMAHEYLQACQALGPRLRDSQIYGFEM
HHHHHHHHHCCCCCCCCCCCCEEHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
WAKEYRGDLGIALSDVYGMDAFLNDFDMYFCKLFDGARHDSGDPFEWGERMLRHYEANRC
HHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCC
DPRTKVLVFSDALDIPKVMQLYERFRGRCKLAFGVGTNLTNDLGYVPLQIVIKMVRCNGQ
CCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCC
PVAKLSDSPGKSMCDDKAYLAYLRQVFGIAQPVDEDASK
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MIITSLLDTDLYKFTMMQVVLHHFPAANVEYRFRCRTPGVDLVPYIDEIRDEVRGLCSLR
CEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
FADVELDYLRRMRFIKSDFVDFLALFHLNEKYISITPSPKGNGEIDIVIEGPWLHTILFE
EECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEEECCHHHHHHHH
IPVLAIVNEVYFRNTQREPDYREGRERLREKIKLLGAKPEFADCKIADYGTRRRFSKVWH
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHH
EEVALTLRDGLGPQFAGTSNVLYAMKHDITPLGTMAHEYLQACQALGPRLRDSQIYGFEM
HHHHHHHHHCCCCCCCCCCCCEEHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
WAKEYRGDLGIALSDVYGMDAFLNDFDMYFCKLFDGARHDSGDPFEWGERMLRHYEANRC
HHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCC
DPRTKVLVFSDALDIPKVMQLYERFRGRCKLAFGVGTNLTNDLGYVPLQIVIKMVRCNGQ
CCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCC
PVAKLSDSPGKSMCDDKAYLAYLRQVFGIAQPVDEDASK
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA