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The map label for this gene is atoC [H]

Identifier: 116689107

GI number: 116689107

Start: 1195578

End: 1196975

Strand: Direct

Name: atoC [H]

Synonym: Bcen2424_1084

Alternate gene names: 116689107

Gene position: 1195578-1196975 (Clockwise)

Preceding gene: 116689104

Following gene: 116689108

Centisome position: 34.32

GC content: 68.03

Gene sequence:

>1398_bases
ATGGGAGCCGATCAGCGGCACGTGATCTACTATTCGCGCGAACCGAACGACGCGTTGCGCGGCCATTTCGACGAATGCGG
CTGGCGCGTCGATCTCGCCGAGACCGTGCGCGATGTGCGGCGCGTCGTGCAGCACGGCGTGGCAACCGCCGGCCTGCTCG
ATTTCTCGCCGGGCTTCAAGCCGTCGGACCTGCGCGAACTCGAATCCTGCCTGAGCATCCAGCACATCGGCTGGATCGCG
GCGACGCGGCGCGGCCAGTTGCAGGACGCGACGCTGCGCCATCTCATTCGCGACTATTGCTTCGACTACGTGACGATGCC
GTACGAAACGGCGCGGATCGTCGAGACCGTCGGTCATGCGCACGGCATGGTCGCCCTGACCGATCCCGTTGCGCCGCCCG
TCGGCGCCGGGCGCAGCGAAGGCGAGATGGTCGGCACCTGCGATGCGATGCTCGGGCTGTTCCGGACGATCCGCCGTGTC
GCGGCGACCGACGCGCCGGTGTTCATCTCCGGCGAGTCGGGCACGGGCAAGGAGTTGACGGCGGTCGCGATTCACGAGCG
TTCGTCGCGCGCGCAGGCGCCGTTCATCGCGATCAATTGCGGGGCGATACCGTCGACGCTGCTGCAGGCCGAACTGTTCG
GCTATGAACGCGGCGCGTTCACCGGCGCGAACCAGCGCAAGATCGGCCGCGTCGAGGCCGCCAACGGCGGCACGCTGTTT
CTCGACGAGATCGGCGATTTGCCGCTCGAAAGCCAGGCGAGCCTGTTGCGCTTCCTGCAGGAAGGCAAGATCGAGCGGCT
CGGCGCGCACGTGTCGGTGCCGGTCGACGTACGCGTGATTTGCGCGACGCACGTGGACATGGAAGCGGCGCTGCGCGAAG
GGCGCTTCCGCGAGGATCTGTTTCACCGGCTGTGCGTGCTGAAGATCGAGGAGCCGCCGTTGCGCGCGCGCGGCAAGGAC
ATCGAGGTGCTCGCGCGTCACATGCTCGAGCGCTTCAAGGGCGATGCGCATCGCCGCCTGCGCGGTTTTTCGCCTGACGC
GGTCGCGTCGCTGTACGGCTATTCGTGGCCGGGCAACGTGCGCGAGCTGATCAACCGCGTGCGCCGCGCGATCGTGATGT
CGGAAGGCCGGATGATCACCGCGGCCGATCTCGAACTGAACGACTATGCAATGCTCGCGCCGGTATCGCTGCTGGAGGCT
CGCGAGGCGGCCGAGCGGCAGGCGATCGAGCAGGCGCTGCTGCGCCATCGCGGCCGTTTTGCCGATGCCGCGCGTGAGCT
CGGCGTGTCGCGCGTCACGCTCTACCGGCTGATGTGCGCGCACGGCATGCGCGACCGCGGCGACACGCTGGGAGGGTTTT
CGGCGCCGTTGCCGGAGCTTCCGCGTCACGCTTGCTAA

Upstream 100 bases:

>100_bases
CATGGCGAATCGAGCCACCTCTGGCTGACCCGATTCGATCCTTTTGCACGTGACCTACGTGTGCGGCAATCGTTAGACGG
TTGATGAACGGGGTGAGGAT

Downstream 100 bases:

>100_bases
AATTGGCGGGTACGGCCGCCCCTCGCGGCCGAAGGAACCCGCATGAAACAGTATCTCGATCTCGTTCGTACCATTCTCGA
TACCGGCACCTGGCAGGAGA

Product: sigma-54 dependent trancsriptional regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MGADQRHVIYYSREPNDALRGHFDECGWRVDLAETVRDVRRVVQHGVATAGLLDFSPGFKPSDLRELESCLSIQHIGWIA
ATRRGQLQDATLRHLIRDYCFDYVTMPYETARIVETVGHAHGMVALTDPVAPPVGAGRSEGEMVGTCDAMLGLFRTIRRV
AATDAPVFISGESGTGKELTAVAIHERSSRAQAPFIAINCGAIPSTLLQAELFGYERGAFTGANQRKIGRVEAANGGTLF
LDEIGDLPLESQASLLRFLQEGKIERLGAHVSVPVDVRVICATHVDMEAALREGRFREDLFHRLCVLKIEEPPLRARGKD
IEVLARHMLERFKGDAHRRLRGFSPDAVASLYGYSWPGNVRELINRVRRAIVMSEGRMITAADLELNDYAMLAPVSLLEA
REAAERQAIEQALLRHRGRFADAARELGVSRVTLYRLMCAHGMRDRGDTLGGFSAPLPELPRHAC

Sequences:

>Translated_465_residues
MGADQRHVIYYSREPNDALRGHFDECGWRVDLAETVRDVRRVVQHGVATAGLLDFSPGFKPSDLRELESCLSIQHIGWIA
ATRRGQLQDATLRHLIRDYCFDYVTMPYETARIVETVGHAHGMVALTDPVAPPVGAGRSEGEMVGTCDAMLGLFRTIRRV
AATDAPVFISGESGTGKELTAVAIHERSSRAQAPFIAINCGAIPSTLLQAELFGYERGAFTGANQRKIGRVEAANGGTLF
LDEIGDLPLESQASLLRFLQEGKIERLGAHVSVPVDVRVICATHVDMEAALREGRFREDLFHRLCVLKIEEPPLRARGKD
IEVLARHMLERFKGDAHRRLRGFSPDAVASLYGYSWPGNVRELINRVRRAIVMSEGRMITAADLELNDYAMLAPVSLLEA
REAAERQAIEQALLRHRGRFADAARELGVSRVTLYRLMCAHGMRDRGDTLGGFSAPLPELPRHAC
>Mature_464_residues
GADQRHVIYYSREPNDALRGHFDECGWRVDLAETVRDVRRVVQHGVATAGLLDFSPGFKPSDLRELESCLSIQHIGWIAA
TRRGQLQDATLRHLIRDYCFDYVTMPYETARIVETVGHAHGMVALTDPVAPPVGAGRSEGEMVGTCDAMLGLFRTIRRVA
ATDAPVFISGESGTGKELTAVAIHERSSRAQAPFIAINCGAIPSTLLQAELFGYERGAFTGANQRKIGRVEAANGGTLFL
DEIGDLPLESQASLLRFLQEGKIERLGAHVSVPVDVRVICATHVDMEAALREGRFREDLFHRLCVLKIEEPPLRARGKDI
EVLARHMLERFKGDAHRRLRGFSPDAVASLYGYSWPGNVRELINRVRRAIVMSEGRMITAADLELNDYAMLAPVSLLEAR
EAAERQAIEQALLRHRGRFADAARELGVSRVTLYRLMCAHGMRDRGDTLGGFSAPLPELPRHAC

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=358, Percent_Identity=41.0614525139665, Blast_Score=265, Evalue=6e-72,
Organism=Escherichia coli, GI1790437, Length=353, Percent_Identity=42.7762039660057, Blast_Score=263, Evalue=2e-71,
Organism=Escherichia coli, GI1790299, Length=374, Percent_Identity=40.9090909090909, Blast_Score=251, Evalue=6e-68,
Organism=Escherichia coli, GI1788905, Length=347, Percent_Identity=40.3458213256484, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI87082117, Length=365, Percent_Identity=40, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI1789233, Length=313, Percent_Identity=43.7699680511182, Blast_Score=231, Evalue=6e-62,
Organism=Escherichia coli, GI1789087, Length=313, Percent_Identity=40.5750798722045, Blast_Score=221, Evalue=8e-59,
Organism=Escherichia coli, GI87082152, Length=324, Percent_Identity=42.5925925925926, Blast_Score=220, Evalue=1e-58,
Organism=Escherichia coli, GI1786524, Length=315, Percent_Identity=43.4920634920635, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI87081872, Length=234, Percent_Identity=44.4444444444444, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1787583, Length=316, Percent_Identity=36.0759493670886, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI87081858, Length=293, Percent_Identity=33.7883959044369, Blast_Score=153, Evalue=3e-38,
Organism=Escherichia coli, GI1789828, Length=243, Percent_Identity=34.9794238683128, Blast_Score=123, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 51438; Mature: 51306

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGADQRHVIYYSREPNDALRGHFDECGWRVDLAETVRDVRRVVQHGVATAGLLDFSPGFK
CCCCCCEEEEEECCCCHHHHCCHHHCCCEEEHHHHHHHHHHHHHHCCHHHCCCCCCCCCC
PSDLRELESCLSIQHIGWIAATRRGQLQDATLRHLIRDYCFDYVTMPYETARIVETVGHA
CHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
HGMVALTDPVAPPVGAGRSEGEMVGTCDAMLGLFRTIRRVAATDAPVFISGESGTGKELT
CCEEEEECCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEE
AVAIHERSSRAQAPFIAINCGAIPSTLLQAELFGYERGAFTGANQRKIGRVEAANGGTLF
EEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCEEE
LDEIGDLPLESQASLLRFLQEGKIERLGAHVSVPVDVRVICATHVDMEAALREGRFREDL
EECCCCCCCCHHHHHHHHHHHCCHHHCCCEEECCCCEEEEEEHHCCHHHHHHCCCHHHHH
FHRLCVLKIEEPPLRARGKDIEVLARHMLERFKGDAHRRLRGFSPDAVASLYGYSWPGNV
HHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHCCCCCCHH
RELINRVRRAIVMSEGRMITAADLELNDYAMLAPVSLLEAREAAERQAIEQALLRHRGRF
HHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
ADAARELGVSRVTLYRLMCAHGMRDRGDTLGGFSAPLPELPRHAC
HHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GADQRHVIYYSREPNDALRGHFDECGWRVDLAETVRDVRRVVQHGVATAGLLDFSPGFK
CCCCCEEEEEECCCCHHHHCCHHHCCCEEEHHHHHHHHHHHHHHCCHHHCCCCCCCCCC
PSDLRELESCLSIQHIGWIAATRRGQLQDATLRHLIRDYCFDYVTMPYETARIVETVGHA
CHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
HGMVALTDPVAPPVGAGRSEGEMVGTCDAMLGLFRTIRRVAATDAPVFISGESGTGKELT
CCEEEEECCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEE
AVAIHERSSRAQAPFIAINCGAIPSTLLQAELFGYERGAFTGANQRKIGRVEAANGGTLF
EEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCEEE
LDEIGDLPLESQASLLRFLQEGKIERLGAHVSVPVDVRVICATHVDMEAALREGRFREDL
EECCCCCCCCHHHHHHHHHHHCCHHHCCCEEECCCCEEEEEEHHCCHHHHHHCCCHHHHH
FHRLCVLKIEEPPLRARGKDIEVLARHMLERFKGDAHRRLRGFSPDAVASLYGYSWPGNV
HHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHCCCCCCHH
RELINRVRRAIVMSEGRMITAADLELNDYAMLAPVSLLEAREAAERQAIEQALLRHRGRF
HHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
ADAARELGVSRVTLYRLMCAHGMRDRGDTLGGFSAPLPELPRHAC
HHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]