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The map label for this gene is pmbA [H]

Identifier: 116689104

GI number: 116689104

Start: 1192500

End: 1193870

Strand: Direct

Name: pmbA [H]

Synonym: Bcen2424_1081

Alternate gene names: 116689104

Gene position: 1192500-1193870 (Clockwise)

Preceding gene: 116689101

Following gene: 116689107

Centisome position: 34.23

GC content: 68.13

Gene sequence:

>1371_bases
ATGGCAGCCAATCTCGACGTACAAGCGCGCTATTTCCCGCACACGCAGGACCAGCTCAAGGAAATCGCGTCGGACATCCT
TCGCCATGCGAAGGCGCTCGGCGCGACCGACGCCGCGACCGAAATCTCCGAGGGCGACGGCCTGTCGGTGTCGGTGCGCC
GCGGCGAAGTCGAAACGATCGAGCACAACCGCGACAAGATGGTCGGCGTCACCGTGTTCATCGGCAAGAAGCGCGGCAAC
GCGAGCACGTCGGACTTCTCGCCGGCCGCGATCAAGGATACCGTCGCCGCCGCGTACAACATCGCGCGCTTCACGGCCGA
GGACGAAGCGGCCGGCCTCGCCGAGGCCGAGCTGCTCGAAACCGACCCGCGCGACCTCGATCTGTACCACCCGTGGGCGC
TGAGCGCCGACGAGGCCGTCGAGCTCGCCCGCCGCGCGGAAGATGCCGCGTTCGCGGTCAGCCCGCAGATCCGCAATTCG
GAAGGCGCGAGCGTGTCGGCGCAGCACTCGCAGTTCGTGCTGGCGACGTCGCGCGGCTTCCTCGCCGGCTATCCGTACTC
GCGCCACTACATCGCATGCGCGCCGATCGCGGGTAGCGGCCGTCACATGCAGCGCGACGACTGGTATTCGTCGAAGCGCA
GCGCGATCGATCTCGCCGCGCCCGAAGCGGTGGGCCGTTACGCGGCCGAACGCGCGCTTGCGCGGATGGGCGCGCGCCGT
CTCGACACGCGCAAGGTGCCCGTGCTGTTCGAGGCGCCGCTCGCGGCCGGCCTGCTCGGCGCATTCGTGCAGGCGGTGAG
CGGCGGTGCGCTGTATCGCAAGACGTCGTTCCTCGTCGACAGCCTCGGCAAGCCGGTGTTCGCGCCGCACATCCAGGTCG
TCGAGGATCCGCACGTGCCGCGCGCGATGGGCAGCGCGCCGTTCGACGAGGAAGGCGTGCGCACGCGGGCGCGCAGCGTC
GTGAAGGACGGCGTCGTCGAAGGCTATTTCCTGTCGACCTATTCGGCACGCAAGCTCGGCACGCAAACCACCGGCAACGC
GGGCGGCTCGCACAACCTCGCGCTGCGCAGCTCGAACACGCAGGCGGGCGACGATTTCGACGCGATGCTGAAGAAGCTCG
GCACGGGTCTGCTGCTGACCGAGCTGATGGGGCAGGGCGTGAACTACGTGACGGGCGACTATTCGCGCGGCGCGGCGGGC
TTCTGGGTGGAGAACGGCGTGATCCAGTATCCGGTCGAGGAAATCACCGTTGCCAGCACGCTGCAGGAGATGTTCCGCCA
TATCGTCGCGATCGGTGCGGATTCGCTCGTGCGCGGCACGAAGGAAACCGGCTCGGTGCTGATCGAGCAGATGACGATCG
CAGGGCAGTAA

Upstream 100 bases:

>100_bases
CCCCAAGCTTGTCTGTGTCCGGCCCCGGACCTTGCTATGATCGCGGGATACGCAACATTTTGACCATGCGGGCGCCCGCC
CGCCACCGGATACCAAGACG

Downstream 100 bases:

>100_bases
GCCGCACGCGGCGCAGGCCGCCAGGAAACGACAAAGCCCGACCGGCGCGAGCCGGTCGGGCTTTTTTCATCGTGCGAAGA
AGTCGTCAGTCGCGCTTGCG

Product: peptidase U62, modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MAANLDVQARYFPHTQDQLKEIASDILRHAKALGATDAATEISEGDGLSVSVRRGEVETIEHNRDKMVGVTVFIGKKRGN
ASTSDFSPAAIKDTVAAAYNIARFTAEDEAAGLAEAELLETDPRDLDLYHPWALSADEAVELARRAEDAAFAVSPQIRNS
EGASVSAQHSQFVLATSRGFLAGYPYSRHYIACAPIAGSGRHMQRDDWYSSKRSAIDLAAPEAVGRYAAERALARMGARR
LDTRKVPVLFEAPLAAGLLGAFVQAVSGGALYRKTSFLVDSLGKPVFAPHIQVVEDPHVPRAMGSAPFDEEGVRTRARSV
VKDGVVEGYFLSTYSARKLGTQTTGNAGGSHNLALRSSNTQAGDDFDAMLKKLGTGLLLTELMGQGVNYVTGDYSRGAAG
FWVENGVIQYPVEEITVASTLQEMFRHIVAIGADSLVRGTKETGSVLIEQMTIAGQ

Sequences:

>Translated_456_residues
MAANLDVQARYFPHTQDQLKEIASDILRHAKALGATDAATEISEGDGLSVSVRRGEVETIEHNRDKMVGVTVFIGKKRGN
ASTSDFSPAAIKDTVAAAYNIARFTAEDEAAGLAEAELLETDPRDLDLYHPWALSADEAVELARRAEDAAFAVSPQIRNS
EGASVSAQHSQFVLATSRGFLAGYPYSRHYIACAPIAGSGRHMQRDDWYSSKRSAIDLAAPEAVGRYAAERALARMGARR
LDTRKVPVLFEAPLAAGLLGAFVQAVSGGALYRKTSFLVDSLGKPVFAPHIQVVEDPHVPRAMGSAPFDEEGVRTRARSV
VKDGVVEGYFLSTYSARKLGTQTTGNAGGSHNLALRSSNTQAGDDFDAMLKKLGTGLLLTELMGQGVNYVTGDYSRGAAG
FWVENGVIQYPVEEITVASTLQEMFRHIVAIGADSLVRGTKETGSVLIEQMTIAGQ
>Mature_455_residues
AANLDVQARYFPHTQDQLKEIASDILRHAKALGATDAATEISEGDGLSVSVRRGEVETIEHNRDKMVGVTVFIGKKRGNA
STSDFSPAAIKDTVAAAYNIARFTAEDEAAGLAEAELLETDPRDLDLYHPWALSADEAVELARRAEDAAFAVSPQIRNSE
GASVSAQHSQFVLATSRGFLAGYPYSRHYIACAPIAGSGRHMQRDDWYSSKRSAIDLAAPEAVGRYAAERALARMGARRL
DTRKVPVLFEAPLAAGLLGAFVQAVSGGALYRKTSFLVDSLGKPVFAPHIQVVEDPHVPRAMGSAPFDEEGVRTRARSVV
KDGVVEGYFLSTYSARKLGTQTTGNAGGSHNLALRSSNTQAGDDFDAMLKKLGTGLLLTELMGQGVNYVTGDYSRGAAGF
WVENGVIQYPVEEITVASTLQEMFRHIVAIGADSLVRGTKETGSVLIEQMTIAGQ

Specific function: May facilitate the secretion of the peptide antibiotic microcin B17 (MccB17) by completing its maturation. Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1790682, Length=439, Percent_Identity=48.0637813211845, Blast_Score=410, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 48851; Mature: 48720

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAANLDVQARYFPHTQDQLKEIASDILRHAKALGATDAATEISEGDGLSVSVRRGEVETI
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCEEEEECCCCHHH
EHNRDKMVGVTVFIGKKRGNASTSDFSPAAIKDTVAAAYNIARFTAEDEAAGLAEAELLE
HCCCCCEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHC
TDPRDLDLYHPWALSADEAVELARRAEDAAFAVSPQIRNSEGASVSAQHSQFVLATSRGF
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCEEECCCCEEEEEECCCC
LAGYPYSRHYIACAPIAGSGRHMQRDDWYSSKRSAIDLAAPEAVGRYAAERALARMGARR
EECCCCCCCEEEEECCCCCCCCCCCCHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHH
LDTRKVPVLFEAPLAAGLLGAFVQAVSGGALYRKTSFLVDSLGKPVFAPHIQVVEDPHVP
CCCCCCCEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCC
RAMGSAPFDEEGVRTRARSVVKDGVVEGYFLSTYSARKLGTQTTGNAGGSHNLALRSSNT
HHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCHHHHCCCCCCCCCCCCCCEEEECCCC
QAGDDFDAMLKKLGTGLLLTELMGQGVNYVTGDYSRGAAGFWVENGVIQYPVEEITVAST
CCCCCHHHHHHHHCCHHHHHHHHHCCCCEEECCCCCCCCCEEEECCEEECCHHHHHHHHH
LQEMFRHIVAIGADSLVRGTKETGSVLIEQMTIAGQ
HHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AANLDVQARYFPHTQDQLKEIASDILRHAKALGATDAATEISEGDGLSVSVRRGEVETI
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCEEEEECCCCHHH
EHNRDKMVGVTVFIGKKRGNASTSDFSPAAIKDTVAAAYNIARFTAEDEAAGLAEAELLE
HCCCCCEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHC
TDPRDLDLYHPWALSADEAVELARRAEDAAFAVSPQIRNSEGASVSAQHSQFVLATSRGF
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCEEECCCCEEEEEECCCC
LAGYPYSRHYIACAPIAGSGRHMQRDDWYSSKRSAIDLAAPEAVGRYAAERALARMGARR
EECCCCCCCEEEEECCCCCCCCCCCCHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHH
LDTRKVPVLFEAPLAAGLLGAFVQAVSGGALYRKTSFLVDSLGKPVFAPHIQVVEDPHVP
CCCCCCCEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCC
RAMGSAPFDEEGVRTRARSVVKDGVVEGYFLSTYSARKLGTQTTGNAGGSHNLALRSSNT
HHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCHHHHCCCCCCCCCCCCCCEEEECCCC
QAGDDFDAMLKKLGTGLLLTELMGQGVNYVTGDYSRGAAGFWVENGVIQYPVEEITVAST
CCCCCHHHHHHHHCCHHHHHHHHHCCCCEEECCCCCCCCCEEEECCEEECCHHHHHHHHH
LQEMFRHIVAIGADSLVRGTKETGSVLIEQMTIAGQ
HHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]