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The map label for this gene is gph2 [H]

Identifier: 116689060

GI number: 116689060

Start: 1149682

End: 1150395

Strand: Reverse

Name: gph2 [H]

Synonym: Bcen2424_1037

Alternate gene names: 116689060

Gene position: 1150395-1149682 (Counterclockwise)

Preceding gene: 116689061

Following gene: 116689056

Centisome position: 33.02

GC content: 69.47

Gene sequence:

>714_bases
ATGACGACTCCCCTTTCGACCGCGCGGATCGCAGACGAACCGCGCCTGTTGCACTGCGATGCGGTCCTGTTCGATCTGGA
TGGCACGCTCGCCGACACGGCGCCCGACCTCGCGGCAGCCGTCAACAAGATGCAGCGCGAGCGCGGCCTGCCCGAAACGT
CGCTCGACGTGTTGCGGCCGCTGGCCTCGGCCGGCGCGCGCGGCCTGCTCGGCGGCGCGTTCGGCATCGATCCTCACACG
CCCGGCTACGAAGCGATGCGCGACGAGTTCCTGGCCAACTACGCGACCGATCTGTGCGTGCATACGACGCTGTTCCCCGG
CATCGGCGACGTGCTCGACGAACTCGATGCGCGCGACGTACGCTGGGGCATCGTCACGAACAAGGCGATGCGGCTCACCG
CACCGCTCGTCGAGCTGCTCGGCCTCGCGCCGCGCGCCGCTTGCGTCGTCGGGGGCGACACAACACCGCACTCGAAACCG
CATCCGGCCCCGCTGCTGCATGCCGCCGAGCAACTGACACTCGCGCCCGAGCGTATCGTCTACGTGGGTGACGACCTGCG
CGACATCCAGGCCGGCAGCGCCGCCGGCATGGCTACGATCGCGGCCGCATACGGCTATTGCGGCGACGGTATCGCGCCGG
CCGACTGGCAGGCCCAGCACCTCGTCGGCACGACGCAGGAGTTGCGGCACCTGCTGCGCGATGTTGGGCTATAA

Upstream 100 bases:

>100_bases
ATCACGTACCACCCGATCGGCAAGCGCTTCGCGCTGTCGAACGACACCGATATCAACTACCTGGTTGCGTGCCGTCGCGG
CGCGTGACCCTCCAACCGGC

Downstream 100 bases:

>100_bases
TGGTCGATCTTATCCGCGGGGGCGACCTGGTTTCGACAGGGGTTGTGAAGCGGCTAGGGCATGTCGAGGACCCGTCACCT
CGTTAATCAATGGGAAAATC

Product: phosphoglycolate phosphatase

Products: NA

Alternate protein names: PGP 2; PGPase2 [H]

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MTTPLSTARIADEPRLLHCDAVLFDLDGTLADTAPDLAAAVNKMQRERGLPETSLDVLRPLASAGARGLLGGAFGIDPHT
PGYEAMRDEFLANYATDLCVHTTLFPGIGDVLDELDARDVRWGIVTNKAMRLTAPLVELLGLAPRAACVVGGDTTPHSKP
HPAPLLHAAEQLTLAPERIVYVGDDLRDIQAGSAAGMATIAAAYGYCGDGIAPADWQAQHLVGTTQELRHLLRDVGL

Sequences:

>Translated_237_residues
MTTPLSTARIADEPRLLHCDAVLFDLDGTLADTAPDLAAAVNKMQRERGLPETSLDVLRPLASAGARGLLGGAFGIDPHT
PGYEAMRDEFLANYATDLCVHTTLFPGIGDVLDELDARDVRWGIVTNKAMRLTAPLVELLGLAPRAACVVGGDTTPHSKP
HPAPLLHAAEQLTLAPERIVYVGDDLRDIQAGSAAGMATIAAAYGYCGDGIAPADWQAQHLVGTTQELRHLLRDVGL
>Mature_236_residues
TTPLSTARIADEPRLLHCDAVLFDLDGTLADTAPDLAAAVNKMQRERGLPETSLDVLRPLASAGARGLLGGAFGIDPHTP
GYEAMRDEFLANYATDLCVHTTLFPGIGDVLDELDARDVRWGIVTNKAMRLTAPLVELLGLAPRAACVVGGDTTPHSKPH
PAPLLHAAEQLTLAPERIVYVGDDLRDIQAGSAAGMATIAAAYGYCGDGIAPADWQAQHLVGTTQELRHLLRDVGL

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=205, Percent_Identity=36.0975609756098, Blast_Score=110, Evalue=8e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 25087; Mature: 24956

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPLSTARIADEPRLLHCDAVLFDLDGTLADTAPDLAAAVNKMQRERGLPETSLDVLRP
CCCCCCCHHHCCCCCEEEECEEEEECCCCHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHH
LASAGARGLLGGAFGIDPHTPGYEAMRDEFLANYATDLCVHTTLFPGIGDVLDELDARDV
HHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCE
RWGIVTNKAMRLTAPLVELLGLAPRAACVVGGDTTPHSKPHPAPLLHAAEQLTLAPERIV
EEEEECCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCEEE
YVGDDLRDIQAGSAAGMATIAAAYGYCGDGIAPADWQAQHLVGTTQELRHLLRDVGL
EECCCHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHCCHHHHHHHHHHCCC
>Mature Secondary Structure 
TTPLSTARIADEPRLLHCDAVLFDLDGTLADTAPDLAAAVNKMQRERGLPETSLDVLRP
CCCCCCHHHCCCCCEEEECEEEEECCCCHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHH
LASAGARGLLGGAFGIDPHTPGYEAMRDEFLANYATDLCVHTTLFPGIGDVLDELDARDV
HHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCE
RWGIVTNKAMRLTAPLVELLGLAPRAACVVGGDTTPHSKPHPAPLLHAAEQLTLAPERIV
EEEEECCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCEEE
YVGDDLRDIQAGSAAGMATIAAAYGYCGDGIAPADWQAQHLVGTTQELRHLLRDVGL
EECCCHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]