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The map label for this gene is pgl [H]

Identifier: 116688989

GI number: 116688989

Start: 1073151

End: 1073831

Strand: Reverse

Name: pgl [H]

Synonym: Bcen2424_0966

Alternate gene names: 116688989

Gene position: 1073831-1073151 (Counterclockwise)

Preceding gene: 116688990

Following gene: 116688988

Centisome position: 30.82

GC content: 71.51

Gene sequence:

>681_bases
GTGATCGAGATCCACGCTTTCGACACCCAGGAAGCGCAAAGCGAAGCGCTCGCGCGCGCCGTCGGCGATGCGCTGCGCGC
GGCGCTTGCCGGCCCCGCGCGCCCCACGCTCGCGGTGTCCGGCGGCACCAGCCCGCGCCCGTTCCTGCATACGCTGTCGC
ACGCGGCGCTCGACTGGGCCGGCGTCGACGTCACGCTGGTCGACGACCGCTGGGTGCCGGACGACGACGCGGCCAGCAAC
GCGCAACTCGTGCGCGACACGCTGCTGCAGCGCGCGGCGGCCCCTGCCCGCTTCCTGCCGCTCGTCGACACGCGCAGCAC
GCTCGACGCGCACGTCGCCGCGTTGAACGCGAACCCCGACTACCGCGTGCCGACCGTCGCCGTGCTCGGCATGGGCGAGG
ACGGCCACACCGCGTCGATCTTCGCCGACGCACCCGAATGGGACCACGCGATCACGACGTCCGAGCGGTTCGTCGCCGTG
CATCCGGGCGCGGCGCCCCATGCACGCGTGAGCTATTCGCTCGATGCGCTCAAGCGCGTCGACCGGCTGTTCCTGCTGAT
CGCGGGCGCCCGCAAACGCGACGTGCTCGACGCCGCGGCCGCGTCGCTGCAGAAGAACGCGATTTCCCAACTGGCCAACG
ACAAGGGGACCCAGCTCGATGTCTACTGGTGCGCAAAGTAA

Upstream 100 bases:

>100_bases
GAAGAAAACTGATGCAAACCGTTGCGGCGTACGCCACCGTACGCGGCAACGCGCCTCACGATTCGTACGATTTGAACAGA
CAAAGCAGTCCGGAGGAGAT

Downstream 100 bases:

>100_bases
GGCGGTCGTCGCGGGTCAGCATGCCGACGGCCCGCGCCTGCTCGCGGACGTCGGCGGCACCAACGCGCGCTTCGCGCTGG
AAACCGGCCCCGGCGAGATC

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MIEIHAFDTQEAQSEALARAVGDALRAALAGPARPTLAVSGGTSPRPFLHTLSHAALDWAGVDVTLVDDRWVPDDDAASN
AQLVRDTLLQRAAAPARFLPLVDTRSTLDAHVAALNANPDYRVPTVAVLGMGEDGHTASIFADAPEWDHAITTSERFVAV
HPGAAPHARVSYSLDALKRVDRLFLLIAGARKRDVLDAAAASLQKNAISQLANDKGTQLDVYWCAK

Sequences:

>Translated_226_residues
MIEIHAFDTQEAQSEALARAVGDALRAALAGPARPTLAVSGGTSPRPFLHTLSHAALDWAGVDVTLVDDRWVPDDDAASN
AQLVRDTLLQRAAAPARFLPLVDTRSTLDAHVAALNANPDYRVPTVAVLGMGEDGHTASIFADAPEWDHAITTSERFVAV
HPGAAPHARVSYSLDALKRVDRLFLLIAGARKRDVLDAAAASLQKNAISQLANDKGTQLDVYWCAK
>Mature_226_residues
MIEIHAFDTQEAQSEALARAVGDALRAALAGPARPTLAVSGGTSPRPFLHTLSHAALDWAGVDVTLVDDRWVPDDDAASN
AQLVRDTLLQRAAAPARFLPLVDTRSTLDAHVAALNANPDYRVPTVAVLGMGEDGHTASIFADAPEWDHAITTSERFVAV
HPGAAPHARVSYSLDALKRVDRLFLLIAGARKRDVLDAAAASLQKNAISQLANDKGTQLDVYWCAK

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI52145310, Length=174, Percent_Identity=32.183908045977, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900 [H]

Pfam domain/function: NA

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 24084; Mature: 24084

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEIHAFDTQEAQSEALARAVGDALRAALAGPARPTLAVSGGTSPRPFLHTLSHAALDWA
CEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHEEC
GVDVTLVDDRWVPDDDAASNAQLVRDTLLQRAAAPARFLPLVDTRSTLDAHVAALNANPD
CCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHEEECCCCCCHHHEEEEEEECCCC
YRVPTVAVLGMGEDGHTASIFADAPEWDHAITTSERFVAVHPGAAPHARVSYSLDALKRV
CCCCEEEEEECCCCCCEEEEEECCCCCCCEECCCCCEEEECCCCCCCCEEEECHHHHHHH
DRLFLLIAGARKRDVLDAAAASLQKNAISQLANDKGTQLDVYWCAK
HHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECC
>Mature Secondary Structure
MIEIHAFDTQEAQSEALARAVGDALRAALAGPARPTLAVSGGTSPRPFLHTLSHAALDWA
CEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHEEC
GVDVTLVDDRWVPDDDAASNAQLVRDTLLQRAAAPARFLPLVDTRSTLDAHVAALNANPD
CCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHEEECCCCCCHHHEEEEEEECCCC
YRVPTVAVLGMGEDGHTASIFADAPEWDHAITTSERFVAVHPGAAPHARVSYSLDALKRV
CCCCEEEEEECCCCCCEEEEEECCCCCCCEECCCCCEEEECCCCCCCCEEEECHHHHHHH
DRLFLLIAGARKRDVLDAAAASLQKNAISQLANDKGTQLDVYWCAK
HHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]