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The map label for this gene is ribD [H]

Identifier: 116688983

GI number: 116688983

Start: 1066110

End: 1067231

Strand: Reverse

Name: ribD [H]

Synonym: Bcen2424_0960

Alternate gene names: 116688983

Gene position: 1067231-1066110 (Counterclockwise)

Preceding gene: 116688984

Following gene: 116688982

Centisome position: 30.63

GC content: 71.75

Gene sequence:

>1122_bases
ATGTTCTCGGATACCGATTTCGCCCACATGCAGCGCGCGCTCGCGCTCGCGGCGCGCGGCATGTACACGACCGCGCCGAA
TCCGCGCGTCGGCTGCGTGATCGTCAAGGACGGCGACGTGATCGGCGAAGGCTTCACGCAGCCGGCCGGCCAGGACCACG
CGGAAGTGCAGGCGCTCAAGGACGCGCGTTCGCGCGGCTACGACGTCGCGGGCTCCACCGTCTACGTGACGCTCGAACCG
TGCAGCCATTTCGGCCGCACGCCGCCGTGCGCGAACGCGCTGATCGACGCGCGCGTCGCGAAGGTCGTCGCCGCGATGGA
AGACCCGAACCCGCAGGTGTCGGGGCGCGGCCTCGGAATGCTGCGCGACGCGGGTATCGACGTGCGCTGCGGGCTGCTCG
CGCATGAAGCCGGCGAGCTGAACATCGGCTTCGTGTCGCGGATGACGCGCGGCCGCCCGTGGGTGCGGATGAAAACCGCC
GCGTCGCTCGACGGCCGCACCGCGCTGCCGTCCGGCGAAAGCCAGTGGATCACCGGCGAGGCCGCGCGCCTCGACGGCCA
TGCGTGGCGCGCCCGTGCGTGCGCGATCCTCACCGGTATCGGCACCGTGCGCGAGGACAATCCGCTGCTGACCGTGCGCG
GCATCGACACGCCGCGCCAGCCGCAACGCATCCTGGTGGACAGCCGCCTCGACCTGCCGCTCGACGCGCGGCTGCTCGAA
GGCGCGCCATTGCTGATCTTCTGCGGCCGGCTCGACGCCGCCGGCGAACTGCGCGCGAACGTGCTGAAGTCGCGCGGCGC
GGAAATCGTGCCGCTCGCGAATGCGCACGGCAAGGTCGACCTGCCCGCGATGCTGGCGGCGCTCGGCGCGCGCGGCGTCA
ACGAGCTGCACGTCGAGGCCGGCCACAAGCTGAACGGTTCGCTGCTGCGCGAACGCTGCGTCGACGAATTGCTGGTGTAT
CTGGCGCCGAGCCTGCTGGGCGCCGACGCGGCCGGCATGTTCGATCTCGCCGCGCCGGCCAGCCTCGAGGCGCGCACCCG
GCTGTCGTTCCACGGTATCGAGCGGGTCGGCGACGACCTGCGCATCCTCGCGCGCGTCGCACCGACCGACACGTCTCACT
GA

Upstream 100 bases:

>100_bases
CTTCGTGTCGAGCACGCACGACGACGCGGTGATCGACGCGACGCTCGCGGCCGCGCGCCGCGCGTTCGCGGCACTCGCCG
CCTGACCCGGGGCCGCGCGC

Downstream 100 bases:

>100_bases
ACGGAATCGCCACGATGTTTACCGGAATTGTCGCGGCCGTCGGCCGCATCGAAACGATCGCCCCGCTCGGCACGTCGGCC
GATGCGGGCGTGCGCCTGAC

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MFSDTDFAHMQRALALAARGMYTTAPNPRVGCVIVKDGDVIGEGFTQPAGQDHAEVQALKDARSRGYDVAGSTVYVTLEP
CSHFGRTPPCANALIDARVAKVVAAMEDPNPQVSGRGLGMLRDAGIDVRCGLLAHEAGELNIGFVSRMTRGRPWVRMKTA
ASLDGRTALPSGESQWITGEAARLDGHAWRARACAILTGIGTVREDNPLLTVRGIDTPRQPQRILVDSRLDLPLDARLLE
GAPLLIFCGRLDAAGELRANVLKSRGAEIVPLANAHGKVDLPAMLAALGARGVNELHVEAGHKLNGSLLRERCVDELLVY
LAPSLLGADAAGMFDLAAPASLEARTRLSFHGIERVGDDLRILARVAPTDTSH

Sequences:

>Translated_373_residues
MFSDTDFAHMQRALALAARGMYTTAPNPRVGCVIVKDGDVIGEGFTQPAGQDHAEVQALKDARSRGYDVAGSTVYVTLEP
CSHFGRTPPCANALIDARVAKVVAAMEDPNPQVSGRGLGMLRDAGIDVRCGLLAHEAGELNIGFVSRMTRGRPWVRMKTA
ASLDGRTALPSGESQWITGEAARLDGHAWRARACAILTGIGTVREDNPLLTVRGIDTPRQPQRILVDSRLDLPLDARLLE
GAPLLIFCGRLDAAGELRANVLKSRGAEIVPLANAHGKVDLPAMLAALGARGVNELHVEAGHKLNGSLLRERCVDELLVY
LAPSLLGADAAGMFDLAAPASLEARTRLSFHGIERVGDDLRILARVAPTDTSH
>Mature_373_residues
MFSDTDFAHMQRALALAARGMYTTAPNPRVGCVIVKDGDVIGEGFTQPAGQDHAEVQALKDARSRGYDVAGSTVYVTLEP
CSHFGRTPPCANALIDARVAKVVAAMEDPNPQVSGRGLGMLRDAGIDVRCGLLAHEAGELNIGFVSRMTRGRPWVRMKTA
ASLDGRTALPSGESQWITGEAARLDGHAWRARACAILTGIGTVREDNPLLTVRGIDTPRQPQRILVDSRLDLPLDARLLE
GAPLLIFCGRLDAAGELRANVLKSRGAEIVPLANAHGKVDLPAMLAALGARGVNELHVEAGHKLNGSLLRERCVDELLVY
LAPSLLGADAAGMFDLAAPASLEARTRLSFHGIERVGDDLRILARVAPTDTSH

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=367, Percent_Identity=46.866485013624, Blast_Score=298, Evalue=5e-82,
Organism=Escherichia coli, GI145693172, Length=176, Percent_Identity=33.5227272727273, Blast_Score=72, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 39729; Mature: 39729

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSDTDFAHMQRALALAARGMYTTAPNPRVGCVIVKDGDVIGEGFTQPAGQDHAEVQALK
CCCCCHHHHHHHHHHHHHCCCEECCCCCCEEEEEEECCCEECCCCCCCCCCCHHHHHHHH
DARSRGYDVAGSTVYVTLEPCSHFGRTPPCANALIDARVAKVVAAMEDPNPQVSGRGLGM
HHHHCCCCCCCCEEEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCE
LRDAGIDVRCGLLAHEAGELNIGFVSRMTRGRPWVRMKTAASLDGRTALPSGESQWITGE
EECCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCEEECC
AARLDGHAWRARACAILTGIGTVREDNPLLTVRGIDTPRQPQRILVDSRLDLPLDARLLE
HHHCCCCHHHHHHHHHEECCCCCCCCCCEEEEECCCCCCCCCEEEECCCCCCCCCHHHHC
GAPLLIFCGRLDAAGELRANVLKSRGAEIVPLANAHGKVDLPAMLAALGARGVNELHVEA
CCCEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHCCCCCEEEECC
GHKLNGSLLRERCVDELLVYLAPSLLGADAAGMFDLAAPASLEARTRLSFHGIERVGDDL
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCHHHHHHHHHHHHHCCHH
RILARVAPTDTSH
EEEEEECCCCCCC
>Mature Secondary Structure
MFSDTDFAHMQRALALAARGMYTTAPNPRVGCVIVKDGDVIGEGFTQPAGQDHAEVQALK
CCCCCHHHHHHHHHHHHHCCCEECCCCCCEEEEEEECCCEECCCCCCCCCCCHHHHHHHH
DARSRGYDVAGSTVYVTLEPCSHFGRTPPCANALIDARVAKVVAAMEDPNPQVSGRGLGM
HHHHCCCCCCCCEEEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCE
LRDAGIDVRCGLLAHEAGELNIGFVSRMTRGRPWVRMKTAASLDGRTALPSGESQWITGE
EECCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCEEECC
AARLDGHAWRARACAILTGIGTVREDNPLLTVRGIDTPRQPQRILVDSRLDLPLDARLLE
HHHCCCCHHHHHHHHHEECCCCCCCCCCEEEEECCCCCCCCCEEEECCCCCCCCCHHHHC
GAPLLIFCGRLDAAGELRANVLKSRGAEIVPLANAHGKVDLPAMLAALGARGVNELHVEA
CCCEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHCCCCCEEEECC
GHKLNGSLLRERCVDELLVYLAPSLLGADAAGMFDLAAPASLEARTRLSFHGIERVGDDL
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCHHHHHHHHHHHHHCCHH
RILARVAPTDTSH
EEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1406588; 9278503; 9068650 [H]