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The map label for this gene is galE [H]

Identifier: 116688904

GI number: 116688904

Start: 985418

End: 986308

Strand: Direct

Name: galE [H]

Synonym: Bcen2424_0881

Alternate gene names: 116688904

Gene position: 985418-986308 (Clockwise)

Preceding gene: 116688903

Following gene: 116688905

Centisome position: 28.28

GC content: 60.38

Gene sequence:

>891_bases
ATGGCAAAAGTTTTCGTCACGGGCCTGGACGGATTTACCGGCCGCTATATGGCGGAGGAGTTGATCCGCTCGGGGCACGA
AGTTTGCGGGATCGTTCACAAGCCGGTTGCCGCTGCGCCGTGGCGAACGCACGTGTGCGATCTGCTTGATACCGACGCGC
TGGTTCGCGTGCTGTCCGACGAAAAGCCGGATGCCGTCGTGCATCTGGCGGCCATTGCGTTCGTTCAGCACGGCGATGTC
GGCGCGATCTATCAGACCAACGTGGTCGGGACGCGCAATCTGCTTGATGCGCTGACGCGCGCCGCGTGTCAGCCGCGGGC
CGTGTTGTTGGCAAGCAGTGCGAACGTCTATGGCAATTCCGACCGCGAAATCATCGACGAATCCACTGCGCCGGCGCCCG
CAAACGATTACGCAATCAGCAAGCTGGCGATGGAAATGGTCGCGCGCATGTGGCAGGACAAACTTCCGATCGTCATCGTG
CGGCCGTTCAATTACACGGGCGTCGGTCAGGACGAGCGATTCCTGCTGCCCAAGATCGTTCGGCATTTTAGCGCGCGCGC
GGAGCGCATCGAGTTGGGCAATCTGAATGTCGTGCGAGATTTCTCGGATGTGCGCATGGTGGTCGCCGCGTATCGGAAGT
TGATCGAAGCCGACTTCGCAGGACGCACGTTCAACGTCTGCTCAGGTATCGGGTATTCGCTGCAGGACGTCTTGGCGACG
GTGCAGGAACTATCCGGGCATGAACTCGAGGTGGCGGTGAATCCGCAGTTCGTGCGCGCGAACGAGGTCCACAAGCTCGT
CGGAAATTGCCGGGCGCTTGAACACGCGATCGGTTCGACTCACGCGATACCGCTTCGCAATACGCTTGCATGGATGCTCG
AACGTCCATGA

Upstream 100 bases:

>100_bases
GAACTCGGCTGGGTGCCGAAGACGACGCTCGAGCAGCTTTGCCAGATGATGGTCGAGGCGGACATTCGTCGCAACGAAGC
AGGCTTCTCGTTCTAAGGCC

Downstream 100 bases:

>100_bases
GCGAACTGATCGTTGACGGCGTGTTCGGCGCGGCCGGCATGCACGGCACGGTCATGGCCAGAAATGCAGGAAATCGGGGC
GGCGCCGATGTTTTCGTCGA

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MAKVFVTGLDGFTGRYMAEELIRSGHEVCGIVHKPVAAAPWRTHVCDLLDTDALVRVLSDEKPDAVVHLAAIAFVQHGDV
GAIYQTNVVGTRNLLDALTRAACQPRAVLLASSANVYGNSDREIIDESTAPAPANDYAISKLAMEMVARMWQDKLPIVIV
RPFNYTGVGQDERFLLPKIVRHFSARAERIELGNLNVVRDFSDVRMVVAAYRKLIEADFAGRTFNVCSGIGYSLQDVLAT
VQELSGHELEVAVNPQFVRANEVHKLVGNCRALEHAIGSTHAIPLRNTLAWMLERP

Sequences:

>Translated_296_residues
MAKVFVTGLDGFTGRYMAEELIRSGHEVCGIVHKPVAAAPWRTHVCDLLDTDALVRVLSDEKPDAVVHLAAIAFVQHGDV
GAIYQTNVVGTRNLLDALTRAACQPRAVLLASSANVYGNSDREIIDESTAPAPANDYAISKLAMEMVARMWQDKLPIVIV
RPFNYTGVGQDERFLLPKIVRHFSARAERIELGNLNVVRDFSDVRMVVAAYRKLIEADFAGRTFNVCSGIGYSLQDVLAT
VQELSGHELEVAVNPQFVRANEVHKLVGNCRALEHAIGSTHAIPLRNTLAWMLERP
>Mature_295_residues
AKVFVTGLDGFTGRYMAEELIRSGHEVCGIVHKPVAAAPWRTHVCDLLDTDALVRVLSDEKPDAVVHLAAIAFVQHGDVG
AIYQTNVVGTRNLLDALTRAACQPRAVLLASSANVYGNSDREIIDESTAPAPANDYAISKLAMEMVARMWQDKLPIVIVR
PFNYTGVGQDERFLLPKIVRHFSARAERIELGNLNVVRDFSDVRMVVAAYRKLIEADFAGRTFNVCSGIGYSLQDVLATV
QELSGHELEVAVNPQFVRANEVHKLVGNCRALEHAIGSTHAIPLRNTLAWMLERP

Specific function: Can have functions other than metabolism of galactose. It also could be involved in preparation of carbohydrate residues for incorporation into complex polymers, such as exopolysaccharides [H]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI4504031, Length=311, Percent_Identity=25.7234726688103, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1788366, Length=349, Percent_Identity=24.9283667621776, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI48994969, Length=269, Percent_Identity=27.5092936802974, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1788353, Length=277, Percent_Identity=26.3537906137184, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI133901786, Length=318, Percent_Identity=26.4150943396226, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI133901788, Length=318, Percent_Identity=26.4150943396226, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI133901790, Length=318, Percent_Identity=26.4150943396226, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17539424, Length=318, Percent_Identity=26.4150943396226, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17539422, Length=318, Percent_Identity=26.4150943396226, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17507723, Length=318, Percent_Identity=26.1006289308176, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17568069, Length=142, Percent_Identity=33.8028169014084, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24158427, Length=311, Percent_Identity=22.8295819935691, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 32552; Mature: 32421

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVFVTGLDGFTGRYMAEELIRSGHEVCGIVHKPVAAAPWRTHVCDLLDTDALVRVLSD
CCEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCC
EKPDAVVHLAAIAFVQHGDVGAIYQTNVVGTRNLLDALTRAACQPRAVLLASSANVYGNS
CCCHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCC
DREIIDESTAPAPANDYAISKLAMEMVARMWQDKLPIVIVRPFNYTGVGQDERFLLPKIV
CHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCHHHHHH
RHFSARAERIELGNLNVVRDFSDVRMVVAAYRKLIEADFAGRTFNVCSGIGYSLQDVLAT
HHHHHHHHEEECCCCEEEECHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHH
VQELSGHELEVAVNPQFVRANEVHKLVGNCRALEHAIGSTHAIPLRNTLAWMLERP
HHHCCCCEEEEEECCCEECHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
AKVFVTGLDGFTGRYMAEELIRSGHEVCGIVHKPVAAAPWRTHVCDLLDTDALVRVLSD
CEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCC
EKPDAVVHLAAIAFVQHGDVGAIYQTNVVGTRNLLDALTRAACQPRAVLLASSANVYGNS
CCCHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCC
DREIIDESTAPAPANDYAISKLAMEMVARMWQDKLPIVIVRPFNYTGVGQDERFLLPKIV
CHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCHHHHHH
RHFSARAERIELGNLNVVRDFSDVRMVVAAYRKLIEADFAGRTFNVCSGIGYSLQDVLAT
HHHHHHHHEEECCCCEEEECHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHH
VQELSGHELEVAVNPQFVRANEVHKLVGNCRALEHAIGSTHAIPLRNTLAWMLERP
HHHCCCCEEEEEECCCEECHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788721 [H]