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The map label for this gene is rmlC [H]

Identifier: 116688896

GI number: 116688896

Start: 976874

End: 977425

Strand: Direct

Name: rmlC [H]

Synonym: Bcen2424_0873

Alternate gene names: 116688896

Gene position: 976874-977425 (Clockwise)

Preceding gene: 116688895

Following gene: 116688897

Centisome position: 28.04

GC content: 62.32

Gene sequence:

>552_bases
ATGGCCATCCAAGTAACGGCAACGGCGCTGCCCGAAGTCAAGATCATCGAGCCGAAGGTGTTCGGCGACGCGCGCGGGTT
CTTCTACGAAAGCTTCAACGGGAAGGAATTCGCCGAGCAGGTCGCACCCGGCGTCGAATTCGTGCAGGACAACCATTCGC
GCTCGTCGAAGGGCGTGCTGCGCGGCCTGCACTATCAGATCCAGCACGCGCAGGGCAAGCTCGTTCGCGTGGTCGAGGGC
GAAGTGTTCGACGTCGCCGTCGACATTCGCAAGGATTCGCCCAACTTCGGCAAGTGGGTGGGTGTGGTGCTGTCGAACGA
CAACCATCGGCAACTGTGGGTGCCGCCCGGTTTCGCGCACGGGTTCGTCGTGCTGTCGGAGGCCGCGCAGTTCCTTTACA
AGACGACCGACTACTGGTTCCCCGAACACGAGCGCAGCATCGTGTGGAACGACCCGGAGATCGGGATCGAGTGGCCGATC
GATTTCGAGCCGCTGCTGGCGGCGAAGGATGCGGCCGGCAAGCGTTTGAGCGAAGCCGAAGTTTATGCGTGA

Upstream 100 bases:

>100_bases
GCAACTGGATCGACGCGGAACAAGTGCTGAAGCTCGCCCAGCCACTCGCGAAGAACGCATACGGTCAGTACCTGAAGAAC
ATTCTTACGGATCAAGTCGC

Downstream 100 bases:

>100_bases
GGTGGGTGTGACTCCTGAGCCGACGATTCTCGTGACGGGTGTGAATGGCCAGGTCGGGTTCGAACTGCTGCGCTCGCTGC
AAGGACTCGGCCGCGTGGTC

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MAIQVTATALPEVKIIEPKVFGDARGFFYESFNGKEFAEQVAPGVEFVQDNHSRSSKGVLRGLHYQIQHAQGKLVRVVEG
EVFDVAVDIRKDSPNFGKWVGVVLSNDNHRQLWVPPGFAHGFVVLSEAAQFLYKTTDYWFPEHERSIVWNDPEIGIEWPI
DFEPLLAAKDAAGKRLSEAEVYA

Sequences:

>Translated_183_residues
MAIQVTATALPEVKIIEPKVFGDARGFFYESFNGKEFAEQVAPGVEFVQDNHSRSSKGVLRGLHYQIQHAQGKLVRVVEG
EVFDVAVDIRKDSPNFGKWVGVVLSNDNHRQLWVPPGFAHGFVVLSEAAQFLYKTTDYWFPEHERSIVWNDPEIGIEWPI
DFEPLLAAKDAAGKRLSEAEVYA
>Mature_182_residues
AIQVTATALPEVKIIEPKVFGDARGFFYESFNGKEFAEQVAPGVEFVQDNHSRSSKGVLRGLHYQIQHAQGKLVRVVEGE
VFDVAVDIRKDSPNFGKWVGVVLSNDNHRQLWVPPGFAHGFVVLSEAAQFLYKTTDYWFPEHERSIVWNDPEIGIEWPID
FEPLLAAKDAAGKRLSEAEVYA

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=169, Percent_Identity=59.1715976331361, Blast_Score=203, Evalue=5e-54,
Organism=Caenorhabditis elegans, GI17550412, Length=153, Percent_Identity=54.2483660130719, Blast_Score=157, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 20601; Mature: 20470

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIQVTATALPEVKIIEPKVFGDARGFFYESFNGKEFAEQVAPGVEFVQDNHSRSSKGVL
CEEEEEECCCCCEEEECCEECCCCCCEEEECCCCHHHHHHHCCCHHHHHCCCCCCHHHHH
RGLHYQIQHAQGKLVRVVEGEVFDVAVDIRKDSPNFGKWVGVVLSNDNHRQLWVPPGFAH
HHHHEEEECCCCCEEEEECCCEEEEEEEEECCCCCCCEEEEEEEECCCCEEEEECCCCCC
GFVVLSEAAQFLYKTTDYWFPEHERSIVWNDPEIGIEWPIDFEPLLAAKDAAGKRLSEAE
HHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCEECCCCCCHHEECCCCCCCCCCCCC
VYA
CCC
>Mature Secondary Structure 
AIQVTATALPEVKIIEPKVFGDARGFFYESFNGKEFAEQVAPGVEFVQDNHSRSSKGVL
EEEEEECCCCCEEEECCEECCCCCCEEEECCCCHHHHHHHCCCHHHHHCCCCCCHHHHH
RGLHYQIQHAQGKLVRVVEGEVFDVAVDIRKDSPNFGKWVGVVLSNDNHRQLWVPPGFAH
HHHHEEEECCCCCEEEEECCCEEEEEEEEECCCCCCCEEEEEEEECCCCEEEEECCCCCC
GFVVLSEAAQFLYKTTDYWFPEHERSIVWNDPEIGIEWPIDFEPLLAAKDAAGKRLSEAE
HHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCEECCCCCCHHEECCCCCCCCCCCCC
VYA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]