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The map label for this gene is gltK [H]

Identifier: 116688694

GI number: 116688694

Start: 747021

End: 747701

Strand: Direct

Name: gltK [H]

Synonym: Bcen2424_0671

Alternate gene names: 116688694

Gene position: 747021-747701 (Clockwise)

Preceding gene: 116688693

Following gene: 116688695

Centisome position: 21.44

GC content: 63.88

Gene sequence:

>681_bases
GTGATGCATCAGTTCGACTGGAGTAGTATTCCCGGCGCGCTGCCGACGCTGTGGTCGGGGGCGGTCGTCACGTTCAAGAT
CACGCTGATCGCGATCGTGATCGGGATCGTCTGGGGCACGCTGCTGGCGCTGCTGCGGCTGTCCGGCGTGAAGCCGCTCG
CATGGTTCGCGAAAGCGTACGTGACGGTGTTCCGCTCGATCCCGCTCGTGATGGTGCTGCTGTGGTTCTTCCTGATCGTG
CCGCAGTTGCTGCAGGGCGTGCTCGGGCTGTCGCCGACGATCGACATCCGCCTCGCGTCGGCCATGGTCGCGTTCTCGTT
GTTCGAAGCCGCGTATTATTCCGAGATCATCCGCGCCGGCATCCAGGCGGTGCCGCGCGGGCAGGTGAACGCCGCGTTCG
CGCTCGGCATGAACTACGCGCAGGCGATGCGCCTCGTGATCCTGCCGCAGGCCTTCCGTGCGATGGTGCCGCTGCTGCTC
ACGCAGGCGATCGTCCTGTTCCAGGATACGTCGCTCGTGTACGTGATCAGTCTCGCGGACTTCTTCCGCACGGCCGCCAA
CGTCGGCGATCGCGACGGCACGACCGTCGAGATGGTCCTGTTCGCCGGCGCATGCTATTTCGTGATTTGCTCGTTGGCGT
CTGCTCTCGTCAAGGGTCTCCAGAAAAAGGTCACAAGATGA

Upstream 100 bases:

>100_bases
TCGCGGTCACGCTCGCCTACGTGCTGATCAACCTCGTCGTGATGGCGTTCATGCGCTGGATCGAAGGCCGCACGCGGCTG
CCCGGCTATATCGGAGGCAA

Downstream 100 bases:

>100_bases
TTTCCATCAAGAACGTTTCGAAGTGGTACGGCCAGTTTCAGGTCCTCACCGAATGCACGACCGAGGTCAAGAAAGGCGAA
GTGGTCGTCGTGTGCGGCCC

Product: polar amino acid ABC transporter, inner membrane subunit

Products: ADP; phosphate; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MMHQFDWSSIPGALPTLWSGAVVTFKITLIAIVIGIVWGTLLALLRLSGVKPLAWFAKAYVTVFRSIPLVMVLLWFFLIV
PQLLQGVLGLSPTIDIRLASAMVAFSLFEAAYYSEIIRAGIQAVPRGQVNAAFALGMNYAQAMRLVILPQAFRAMVPLLL
TQAIVLFQDTSLVYVISLADFFRTAANVGDRDGTTVEMVLFAGACYFVICSLASALVKGLQKKVTR

Sequences:

>Translated_226_residues
MMHQFDWSSIPGALPTLWSGAVVTFKITLIAIVIGIVWGTLLALLRLSGVKPLAWFAKAYVTVFRSIPLVMVLLWFFLIV
PQLLQGVLGLSPTIDIRLASAMVAFSLFEAAYYSEIIRAGIQAVPRGQVNAAFALGMNYAQAMRLVILPQAFRAMVPLLL
TQAIVLFQDTSLVYVISLADFFRTAANVGDRDGTTVEMVLFAGACYFVICSLASALVKGLQKKVTR
>Mature_226_residues
MMHQFDWSSIPGALPTLWSGAVVTFKITLIAIVIGIVWGTLLALLRLSGVKPLAWFAKAYVTVFRSIPLVMVLLWFFLIV
PQLLQGVLGLSPTIDIRLASAMVAFSLFEAAYYSEIIRAGIQAVPRGQVNAAFALGMNYAQAMRLVILPQAFRAMVPLLL
TQAIVLFQDTSLVYVISLADFFRTAANVGDRDGTTVEMVLFAGACYFVICSLASALVKGLQKKVTR

Specific function: Part of the binding-protein-dependent transport system for aspartate/glutamate; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786873, Length=222, Percent_Identity=72.0720720720721, Blast_Score=322, Evalue=9e-90,
Organism=Escherichia coli, GI1788226, Length=214, Percent_Identity=35.0467289719626, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI87082239, Length=210, Percent_Identity=33.8095238095238, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1786874, Length=214, Percent_Identity=31.3084112149533, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1787087, Length=227, Percent_Identity=28.6343612334802, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1787030, Length=225, Percent_Identity=28.8888888888889, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788645, Length=217, Percent_Identity=25.3456221198157, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI48994930, Length=129, Percent_Identity=34.1085271317829, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788646, Length=209, Percent_Identity=24.4019138755981, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787086, Length=214, Percent_Identity=24.2990654205607, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24664; Mature: 24664

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMHQFDWSSIPGALPTLWSGAVVTFKITLIAIVIGIVWGTLLALLRLSGVKPLAWFAKAY
CCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VTVFRSIPLVMVLLWFFLIVPQLLQGVLGLSPTIDIRLASAMVAFSLFEAAYYSEIIRAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQAVPRGQVNAAFALGMNYAQAMRLVILPQAFRAMVPLLLTQAIVLFQDTSLVYVISLAD
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
FFRTAANVGDRDGTTVEMVLFAGACYFVICSLASALVKGLQKKVTR
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMHQFDWSSIPGALPTLWSGAVVTFKITLIAIVIGIVWGTLLALLRLSGVKPLAWFAKAY
CCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VTVFRSIPLVMVLLWFFLIVPQLLQGVLGLSPTIDIRLASAMVAFSLFEAAYYSEIIRAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQAVPRGQVNAAFALGMNYAQAMRLVILPQAFRAMVPLLLTQAIVLFQDTSLVYVISLAD
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
FFRTAANVGDRDGTTVEMVLFAGACYFVICSLASALVKGLQKKVTR
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamate [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamate [Periplasm] + H2O = ADP + phosphate + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]