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The map label for this gene is exbB [H]

Identifier: 116688675

GI number: 116688675

Start: 724875

End: 725543

Strand: Direct

Name: exbB [H]

Synonym: Bcen2424_0652

Alternate gene names: 116688675

Gene position: 724875-725543 (Clockwise)

Preceding gene: 116688674

Following gene: 116688676

Centisome position: 20.81

GC content: 71.15

Gene sequence:

>669_bases
ATGGCGATTCCCACCGGCGTTGTCCACTACCTCGAAAGCGGCGATGCGATCACGCACGCCGTCTCCTATGTGCTGCTGGC
GATGTCGGTCGCCAGCTGGTGCTTCCTCTTCATGAAAGCTTGGCTGCTGGTCCGCGCGAAGCGGCAGGGGCCGCGCGCGC
TCGCCGCGTTCTGGCGCGCGCCGTCGCTCGACGCGGGCATTGCCGCGCTGGCCGGCGCCGATCGCGAGCGCGTGTTCGTG
CCGCTCGCCGAAGCCGCGCGCGATGCGGCCGACGATCACGACCCCACCGCGCTGGCCGCGCGCGTCGAGCGTAGCGAACG
CGTGCTGCGCGCGTTGCGTCACGCGATGCTGCGCTCGCAGCGGCGCCTCGAATTCGGCCAGGTGCTGCTCGCGTCGATCG
GCAGCACCGCGCCGTTCGTCGGGCTGCTCGGCACCGTGTGGGGCATCTATCACGCACTCGGCAGCATCGCCGCGAGCGGG
CAGGCGCAGATCGAGAACGTCGCGGGGCCGGTCGGCGAGGCGCTGATCATGACCGCGTTCGGGCTGGTCGTCGCGATTCC
CGCGGTGCTCGCGTACAACATCCTCGGCCGGCTCGTCCGGCAGCTCGCCGAGGAGCTCGACGGCTTCGCACGCGATCTGC
ACGTCTTCGTGTGCGCGCAGGGCGTCTGA

Upstream 100 bases:

>100_bases
GGGCGCGTTGCGGGCGGTCCGCTTCCTGTCGGCGCGCGGCGCCGGCCTGTTCGACATGCAGGACGTGCTCGGCCTGCGCT
GACCCCGCGAGGAAACTCCG

Downstream 100 bases:

>100_bases
CGCGCCGGCTCCGGAGGAACGATCATGGCATTCGGCGGGCTCGAGCACCACAAGACGTCCGCGCCGATGGCGGAGATCAA
CATGACGCCGCTGATCGACG

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MAIPTGVVHYLESGDAITHAVSYVLLAMSVASWCFLFMKAWLLVRAKRQGPRALAAFWRAPSLDAGIAALAGADRERVFV
PLAEAARDAADDHDPTALAARVERSERVLRALRHAMLRSQRRLEFGQVLLASIGSTAPFVGLLGTVWGIYHALGSIAASG
QAQIENVAGPVGEALIMTAFGLVVAIPAVLAYNILGRLVRQLAEELDGFARDLHVFVCAQGV

Sequences:

>Translated_222_residues
MAIPTGVVHYLESGDAITHAVSYVLLAMSVASWCFLFMKAWLLVRAKRQGPRALAAFWRAPSLDAGIAALAGADRERVFV
PLAEAARDAADDHDPTALAARVERSERVLRALRHAMLRSQRRLEFGQVLLASIGSTAPFVGLLGTVWGIYHALGSIAASG
QAQIENVAGPVGEALIMTAFGLVVAIPAVLAYNILGRLVRQLAEELDGFARDLHVFVCAQGV
>Mature_221_residues
AIPTGVVHYLESGDAITHAVSYVLLAMSVASWCFLFMKAWLLVRAKRQGPRALAAFWRAPSLDAGIAALAGADRERVFVP
LAEAARDAADDHDPTALAARVERSERVLRALRHAMLRSQRRLEFGQVLLASIGSTAPFVGLLGTVWGIYHALGSIAASGQ
AQIENVAGPVGEALIMTAFGLVVAIPAVLAYNILGRLVRQLAEELDGFARDLHVFVCAQGV

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=197, Percent_Identity=34.5177664974619, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789381, Length=198, Percent_Identity=32.3232323232323, Blast_Score=80, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 23709; Mature: 23578

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIPTGVVHYLESGDAITHAVSYVLLAMSVASWCFLFMKAWLLVRAKRQGPRALAAFWRA
CCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCC
PSLDAGIAALAGADRERVFVPLAEAARDAADDHDPTALAARVERSERVLRALRHAMLRSQ
CCCCHHHHHHHCCCCCCEEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLEFGQVLLASIGSTAPFVGLLGTVWGIYHALGSIAASGQAQIENVAGPVGEALIMTAF
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHHHHHHH
GLVVAIPAVLAYNILGRLVRQLAEELDGFARDLHVFVCAQGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AIPTGVVHYLESGDAITHAVSYVLLAMSVASWCFLFMKAWLLVRAKRQGPRALAAFWRA
CCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCC
PSLDAGIAALAGADRERVFVPLAEAARDAADDHDPTALAARVERSERVLRALRHAMLRSQ
CCCCHHHHHHHCCCCCCEEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLEFGQVLLASIGSTAPFVGLLGTVWGIYHALGSIAASGQAQIENVAGPVGEALIMTAF
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHHHHHHH
GLVVAIPAVLAYNILGRLVRQLAEELDGFARDLHVFVCAQGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9371459 [H]