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The map label for this gene is degQ [H]

Identifier: 116688463

GI number: 116688463

Start: 484755

End: 485960

Strand: Reverse

Name: degQ [H]

Synonym: Bcen2424_0439

Alternate gene names: 116688463

Gene position: 485960-484755 (Counterclockwise)

Preceding gene: 116688475

Following gene: 116688433

Centisome position: 13.95

GC content: 66.42

Gene sequence:

>1206_bases
ATGCTTAGACGCTTCTGGCTGTTCTTCGCGCAGGCGGTGACCGTACTGCTCGCGCTGATGTTCATCGTCGTGACGCTCAA
GCCGCAATGGCTGCAACGGCAAGGACAGCTCGGCAAGCAGCTCGCCACGCCGATCGTCGCGCTGCGGGAAGTCGCGCCGG
GCATCGGCGGCGCACCGGCGACCACGTCGTACGCCGAAGCCGCGCAGAAGGCGATGCCGGCCGTCGTCAACGTGTTCTCC
AGCAAGGACGGCTCGCTGCCGCCCGACCCGCGCGCGAAAGATCCGCTGTTCCGTTACTTCTTCGGCGACCGCAACGCCCG
CAAGCAGCAGGACGAGCCGGCCGCCAACCTCGGCTCGGGCGTTATCGTGAGCCCTGAAGGTTACATTCTAACGAACCAGC
ACGTCGTGGACGGCGCCGACCAGATCGAAGTCGCGCTCGCCGACGGCCGCACGGCCACCGCGAAAGTGATCGGCAGCGAT
CCCGAAACCGATCTCGCGGTGCTGAAGATCAACATGACGAACCTGCCGACGATCACGCTCGGCCGCTCCGACCAGTCGCG
CGTCGGCGACGTCGTGCTCGCGATCGGCAATCCGTTTGGCGTCGGCCAGACGGTCACGATGGGGATCATCAGCGCGCTCG
GCCGCAACCACCTCGGCATCAACACGTTCGAGAACTTCATCCAGACCGATGCGCCGATCAACCCCGGCAACTCCGGCGGC
GCGCTGGTCGACGTGAACGGCAACCTGCTCGGCATCAACACGGCGATCTACTCGCGCTCGGGCGGCTCGCTCGGCATCGG
TTTCGCGATTCCCGTCTCGACCGCTCGCACGGTGCTCGAGAGCATCATCACGACGGGCTCGGTCACGCGCGGCTGGATCG
GCGTCGAGCCGCAGGACGTCACGCCGGAAATCGCCGAGTCGTTCGGGCTGCAGCAGAAATCGGGCGCGATCGTCGCGGGC
GTGCTGCAGGGCGGTCCGGCCGACAAGGCCGGCATCAAGCCGGGCGACATCCTGGTGAGCGTGAACGGCGACGAAATCAC
CGACACGACGAAGCTGCTGAACACCGTCGCGCAGATCAAGCCGGGCACGCCGACCAAGGTGCACGTCGTACGCAAGGGCA
AGCAGTTCGACGTGAACGTCGTGATCGGCAAGCGCCCGCCGCCGCCGAAGCAGGCGCTCGACGAGCAGGACAACGATAGC
GAATGA

Upstream 100 bases:

>100_bases
GGCCGTTCGGGCAATAGTCCTTGAAGCGCGCGGTTTCAAGGGTATTGTTCAAGTACAATTCAAGTTCGATCCGATCCATA
TAAACCTCTAATCCATTCAG

Downstream 100 bases:

>100_bases
GGGTCGGCGGCCGGTGCGCCGCCTGCCGGTCGCGATGCGAGGCAACGCGACGCGGAAATGAAAAAGGGCAGCCATCGGCT
GCCCTTTTGCTTTGCGTCTG

Product: peptidase S1 and S6, chymotrypsin/Hap

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MLRRFWLFFAQAVTVLLALMFIVVTLKPQWLQRQGQLGKQLATPIVALREVAPGIGGAPATTSYAEAAQKAMPAVVNVFS
SKDGSLPPDPRAKDPLFRYFFGDRNARKQQDEPAANLGSGVIVSPEGYILTNQHVVDGADQIEVALADGRTATAKVIGSD
PETDLAVLKINMTNLPTITLGRSDQSRVGDVVLAIGNPFGVGQTVTMGIISALGRNHLGINTFENFIQTDAPINPGNSGG
ALVDVNGNLLGINTAIYSRSGGSLGIGFAIPVSTARTVLESIITTGSVTRGWIGVEPQDVTPEIAESFGLQQKSGAIVAG
VLQGGPADKAGIKPGDILVSVNGDEITDTTKLLNTVAQIKPGTPTKVHVVRKGKQFDVNVVIGKRPPPPKQALDEQDNDS
E

Sequences:

>Translated_401_residues
MLRRFWLFFAQAVTVLLALMFIVVTLKPQWLQRQGQLGKQLATPIVALREVAPGIGGAPATTSYAEAAQKAMPAVVNVFS
SKDGSLPPDPRAKDPLFRYFFGDRNARKQQDEPAANLGSGVIVSPEGYILTNQHVVDGADQIEVALADGRTATAKVIGSD
PETDLAVLKINMTNLPTITLGRSDQSRVGDVVLAIGNPFGVGQTVTMGIISALGRNHLGINTFENFIQTDAPINPGNSGG
ALVDVNGNLLGINTAIYSRSGGSLGIGFAIPVSTARTVLESIITTGSVTRGWIGVEPQDVTPEIAESFGLQQKSGAIVAG
VLQGGPADKAGIKPGDILVSVNGDEITDTTKLLNTVAQIKPGTPTKVHVVRKGKQFDVNVVIGKRPPPPKQALDEQDNDS
E
>Mature_401_residues
MLRRFWLFFAQAVTVLLALMFIVVTLKPQWLQRQGQLGKQLATPIVALREVAPGIGGAPATTSYAEAAQKAMPAVVNVFS
SKDGSLPPDPRAKDPLFRYFFGDRNARKQQDEPAANLGSGVIVSPEGYILTNQHVVDGADQIEVALADGRTATAKVIGSD
PETDLAVLKINMTNLPTITLGRSDQSRVGDVVLAIGNPFGVGQTVTMGIISALGRNHLGINTFENFIQTDAPINPGNSGG
ALVDVNGNLLGINTAIYSRSGGSLGIGFAIPVSTARTVLESIITTGSVTRGWIGVEPQDVTPEIAESFGLQQKSGAIVAG
VLQGGPADKAGIKPGDILVSVNGDEITDTTKLLNTVAQIKPGTPTKVHVVRKGKQFDVNVVIGKRPPPPKQALDEQDNDS
E

Specific function: Protease with a shared specificity with degP [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=327, Percent_Identity=34.2507645259939, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI24308541, Length=254, Percent_Identity=35.0393700787402, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI7019477, Length=286, Percent_Identity=34.965034965035, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI22129776, Length=262, Percent_Identity=35.4961832061069, Blast_Score=130, Evalue=2e-30,
Organism=Escherichia coli, GI1789629, Length=326, Percent_Identity=45.398773006135, Blast_Score=267, Evalue=9e-73,
Organism=Escherichia coli, GI1786356, Length=343, Percent_Identity=42.8571428571429, Blast_Score=248, Evalue=6e-67,
Organism=Escherichia coli, GI1789630, Length=328, Percent_Identity=42.9878048780488, Blast_Score=229, Evalue=3e-61,
Organism=Drosophila melanogaster, GI24646839, Length=284, Percent_Identity=35.5633802816901, Blast_Score=145, Evalue=7e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 42167; Mature: 42167

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRRFWLFFAQAVTVLLALMFIVVTLKPQWLQRQGQLGKQLATPIVALREVAPGIGGAPA
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
TTSYAEAAQKAMPAVVNVFSSKDGSLPPDPRAKDPLFRYFFGDRNARKQQDEPAANLGSG
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCHHHCCCC
VIVSPEGYILTNQHVVDGADQIEVALADGRTATAKVIGSDPETDLAVLKINMTNLPTITL
EEECCCCEEEECCEEECCCCEEEEEEECCCEEEEEEECCCCCCCEEEEEEECCCCCEEEE
GRSDQSRVGDVVLAIGNPFGVGQTVTMGIISALGRNHLGINTFENFIQTDAPINPGNSGG
CCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCC
ALVDVNGNLLGINTAIYSRSGGSLGIGFAIPVSTARTVLESIITTGSVTRGWIGVEPQDV
EEEEECCCEEEEEEEEEECCCCCEEEEEEECHHHHHHHHHHHHHCCCCCCCEECCCCCCC
TPEIAESFGLQQKSGAIVAGVLQGGPADKAGIKPGDILVSVNGDEITDTTKLLNTVAQIK
CHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCC
PGTPTKVHVVRKGKQFDVNVVIGKRPPPPKQALDEQDNDSE
CCCCCEEEEEECCCEEEEEEEECCCCCCCHHHCCCCCCCCC
>Mature Secondary Structure
MLRRFWLFFAQAVTVLLALMFIVVTLKPQWLQRQGQLGKQLATPIVALREVAPGIGGAPA
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
TTSYAEAAQKAMPAVVNVFSSKDGSLPPDPRAKDPLFRYFFGDRNARKQQDEPAANLGSG
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCHHHCCCC
VIVSPEGYILTNQHVVDGADQIEVALADGRTATAKVIGSDPETDLAVLKINMTNLPTITL
EEECCCCEEEECCEEECCCCEEEEEEECCCEEEEEEECCCCCCCEEEEEEECCCCCEEEE
GRSDQSRVGDVVLAIGNPFGVGQTVTMGIISALGRNHLGINTFENFIQTDAPINPGNSGG
CCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCC
ALVDVNGNLLGINTAIYSRSGGSLGIGFAIPVSTARTVLESIITTGSVTRGWIGVEPQDV
EEEEECCCEEEEEEEEEECCCCCEEEEEEECHHHHHHHHHHHHHCCCCCCCEECCCCCCC
TPEIAESFGLQQKSGAIVAGVLQGGPADKAGIKPGDILVSVNGDEITDTTKLLNTVAQIK
CHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCC
PGTPTKVHVVRKGKQFDVNVVIGKRPPPPKQALDEQDNDSE
CCCCCEEEEEECCCEEEEEEEECCCCCCCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8576051; 9278503 [H]