BacMap

Definition	Burkholderia cenocepacia HI2424 chromosome 1, complete sequence.
Accession	NC_008542
Length	3,483,902

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The map label for this gene is fabG [H]

Identifier: 116688432

GI number: 116688432

Start: 459839

End: 460615

Strand: Reverse

Name: fabG [H]

Synonym: Bcen2424_0408

Alternate gene names: 116688432

Gene position: 460615-459839 (Counterclockwise)

Preceding gene: 116688433

Following gene: 116688431

Centisome position: 13.22

GC content: 74.52

Gene sequence:

>777_bases
GTGAACGCACGCGCCGCGCACCTCGAACGCATCGCGCTGATCACCGGCGCAGGCTCGGGGATCGGCGCGGCGCTCGCGCG
GCGGCTCGCGGCGCCCGGCATCGCGCTGGCGCTGCATGCGCGCGGCGCGGACGAGGCGGCACGATCGCGGCTCGCCGACG
TCGCCCATGCGTGCACGACGGCCGGCGCCGAGTGCATCACGCTGACCGGCGATCTCGGCGAACCGGGTATCGCCGCCGCA
CTGGTCGATAGCACCGCGACGCGCTTCGGCGGGCTCGACCAGCTCGTCGCGAACGCCGGCTTCGCCGCGCGGCAATCCTT
TTCCGAGCTCTCCGCGAACGCACTCGCGTCCGCCTTCGCGACGATGCCCGGGGCGTTCTCCGCGCTCGCGGGCCGCGCGC
GGCCGCTGCTCGAAACGTCGGCCACGCCGCGGATCGTCGCGGTCAGTTCGTTCGTCGCGCACCGCTACCGCGCCGATGCA
CCGTTCGCGACGACCGCCGCCGCGAAGGCCGCGCTCGAATCGCTGGTGCGTAGCGCGGCCGCCGAATTCGCCGCGCACGG
CATCACCGTCAATGCGGTCGCGCCGGGCTTCACGCGCAAGGACCATGGGCCGAGCGCCGGCAACGCCGCCGCGTGGGCGC
AGGCCGAACAGGCGACGCCGCTCGGCCGCATCGCGGAACCCGACGACGTCGCCGCGCTGATCGCGTTCCTGCTGTCGGAC
GCGGCACGGCAGATCACCGGCCAGGTCATCCACGTCGACGGCGGCCTGACGCTCTGA

Upstream 100 bases:

>100_bases
AGGCTGCGATCGTCAGCATCGCGCACCGCGAGTCGCTGGCCGCGTTCCACGTCGGCACGATCAACGTCGAGCGCGTGGGC
AGCGACGACAAGGTCGCCGC

Downstream 100 bases:

>100_bases
CGCGTCCTCCCTCCTGCCTGCTTTTCAGCACAAACCTGCATCCGCCTTTTTGGCATGCCGGAGCGCGCCCGTAAAATAAC
CGCGACGCGGTAGCGCGGGA

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MNARAAHLERIALITGAGSGIGAALARRLAAPGIALALHARGADEAARSRLADVAHACTTAGAECITLTGDLGEPGIAAA
LVDSTATRFGGLDQLVANAGFAARQSFSELSANALASAFATMPGAFSALAGRARPLLETSATPRIVAVSSFVAHRYRADA
PFATTAAAKAALESLVRSAAAEFAAHGITVNAVAPGFTRKDHGPSAGNAAAWAQAEQATPLGRIAEPDDVAALIAFLLSD
AARQITGQVIHVDGGLTL

Sequences:

>Translated_258_residues
MNARAAHLERIALITGAGSGIGAALARRLAAPGIALALHARGADEAARSRLADVAHACTTAGAECITLTGDLGEPGIAAA
LVDSTATRFGGLDQLVANAGFAARQSFSELSANALASAFATMPGAFSALAGRARPLLETSATPRIVAVSSFVAHRYRADA
PFATTAAAKAALESLVRSAAAEFAAHGITVNAVAPGFTRKDHGPSAGNAAAWAQAEQATPLGRIAEPDDVAALIAFLLSD
AARQITGQVIHVDGGLTL
>Mature_258_residues
MNARAAHLERIALITGAGSGIGAALARRLAAPGIALALHARGADEAARSRLADVAHACTTAGAECITLTGDLGEPGIAAA
LVDSTATRFGGLDQLVANAGFAARQSFSELSANALASAFATMPGAFSALAGRARPLLETSATPRIVAVSSFVAHRYRADA
PFATTAAAKAALESLVRSAAAEFAAHGITVNAVAPGFTRKDHGPSAGNAAAWAQAEQATPLGRIAEPDDVAALIAFLLSD
AARQITGQVIHVDGGLTL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI5031737, Length=251, Percent_Identity=29.8804780876494, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI19923817, Length=257, Percent_Identity=28.4046692607004, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI32483357, Length=274, Percent_Identity=28.4671532846715, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI7705925, Length=263, Percent_Identity=31.9391634980989, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI15277342, Length=253, Percent_Identity=28.4584980237154, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI40254992, Length=252, Percent_Identity=26.5873015873016, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI10190704, Length=254, Percent_Identity=28.3464566929134, Blast_Score=64, Evalue=1e-10,
Organism=Escherichia coli, GI1788459, Length=252, Percent_Identity=31.3492063492063, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87082100, Length=259, Percent_Identity=32.4324324324324, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1787335, Length=261, Percent_Identity=31.0344827586207, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI2367175, Length=249, Percent_Identity=31.7269076305221, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1789378, Length=252, Percent_Identity=31.3492063492063, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789208, Length=250, Percent_Identity=27.2, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787905, Length=246, Percent_Identity=28.8617886178862, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI2367365, Length=246, Percent_Identity=30.0813008130081, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1790717, Length=247, Percent_Identity=27.1255060728745, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786812, Length=259, Percent_Identity=30.5019305019305, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=265, Percent_Identity=29.0566037735849, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17560332, Length=269, Percent_Identity=31.9702602230483, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17562906, Length=265, Percent_Identity=30.9433962264151, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17562910, Length=267, Percent_Identity=28.8389513108614, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17536025, Length=261, Percent_Identity=28.3524904214559, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17559104, Length=265, Percent_Identity=30.9433962264151, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17536651, Length=262, Percent_Identity=28.6259541984733, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17560220, Length=273, Percent_Identity=30.7692307692308, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=31.203007518797, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17560676, Length=261, Percent_Identity=30.2681992337165, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17562908, Length=265, Percent_Identity=29.811320754717, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71994600, Length=259, Percent_Identity=29.7297297297297, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17538486, Length=268, Percent_Identity=28.7313432835821, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=263, Percent_Identity=27.3764258555133, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=27.4436090225564, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17561402, Length=255, Percent_Identity=27.0588235294118, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=261, Percent_Identity=28.735632183908, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=29.1666666666667, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI72000259, Length=271, Percent_Identity=30.6273062730627, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=259, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=266, Percent_Identity=27.4436090225564, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=255, Percent_Identity=27.4509803921569, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17561272, Length=248, Percent_Identity=27.0161290322581, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17508651, Length=267, Percent_Identity=27.7153558052434, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=267, Percent_Identity=29.2134831460674, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=268, Percent_Identity=28.3582089552239, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17563726, Length=262, Percent_Identity=29.3893129770992, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=263, Percent_Identity=26.9961977186312, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=252, Percent_Identity=28.1746031746032, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21355319, Length=251, Percent_Identity=31.0756972111554, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI23397609, Length=258, Percent_Identity=31.0077519379845, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24644339, Length=253, Percent_Identity=32.0158102766798, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21357041, Length=254, Percent_Identity=30.7086614173228, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28571526, Length=253, Percent_Identity=31.6205533596838, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24639444, Length=257, Percent_Identity=28.4046692607004, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24644337, Length=253, Percent_Identity=32.4110671936759, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24643142, Length=255, Percent_Identity=29.4117647058824, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25821; Mature: 25821

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNARAAHLERIALITGAGSGIGAALARRLAAPGIALALHARGADEAARSRLADVAHACTT
CCCHHHHHHHEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHH
AGAECITLTGDLGEPGIAAALVDSTATRFGGLDQLVANAGFAARQSFSELSANALASAFA
CCCEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
TMPGAFSALAGRARPLLETSATPRIVAVSSFVAHRYRADAPFATTAAAKAALESLVRSAA
HCCHHHHHHHHCCCHHHHCCCCCCEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
AEFAAHGITVNAVAPGFTRKDHGPSAGNAAAWAQAEQATPLGRIAEPDDVAALIAFLLSD
HHHHHCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
AARQITGQVIHVDGGLTL
HHHHHCCEEEEECCCCCC
>Mature Secondary Structure
MNARAAHLERIALITGAGSGIGAALARRLAAPGIALALHARGADEAARSRLADVAHACTT
CCCHHHHHHHEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHH
AGAECITLTGDLGEPGIAAALVDSTATRFGGLDQLVANAGFAARQSFSELSANALASAFA
CCCEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
TMPGAFSALAGRARPLLETSATPRIVAVSSFVAHRYRADAPFATTAAAKAALESLVRSAA
HCCHHHHHHHHCCCHHHHCCCCCCEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
AEFAAHGITVNAVAPGFTRKDHGPSAGNAAAWAQAEQATPLGRIAEPDDVAALIAFLLSD
HHHHHCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
AARQITGQVIHVDGGLTL
HHHHHCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9384377; 9534248; 8654983 [H]