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The map label for this gene is mmlH [H]

Identifier: 116688431

GI number: 116688431

Start: 458448

End: 459710

Strand: Reverse

Name: mmlH [H]

Synonym: Bcen2424_0407

Alternate gene names: 116688431

Gene position: 459710-458448 (Counterclockwise)

Preceding gene: 116688432

Following gene: 116688430

Centisome position: 13.2

GC content: 66.75

Gene sequence:

>1263_bases
ATGCAGGCATTCCAGTGGTTCAACGAATTGTCGACGCGCGAGCGCCGGACGCTGTACGCCGGATTCGGCGGCTATGCGGT
CGATGCGTTCGACTTCATGATCTATTCGTTCCTGATCCCGACGCTGATCGCCACCTGGGGCATGACGAAGAGCGAGGCCG
GGATGATCGCGACCAGTTCGCTGATCTCGTCGGCGATCGGCGGCTGGGTCGCCGGCATCCTCGCCGACCGCTATGGCCGC
GTGCGCGTGTTGCAGTGGACGATCGCGACGTTCGCGCTGTTCACGTGCCTGTCCGGCTTCACGCATTCGTTCTGGCAGCT
CCTTGCGACGCGCACGCTGCAGGGTTTCGGCTTCGGCGGCGAATGGTCGGTCGTGACGATCATGATGGCCGAGACGATCC
GCTCGCCCGAGCATCGCGCGAAGGCCGTCGGCACCGTGCAGAGCAGCTGGTCGTTCGGCTGGGGCGCGGCCGCGATCCTC
TACTGGGCGTTCTTCGCGCTGCTGCCGGAGCAGGTCGCGTGGCGCGCGTGCTTCTGGATCGGCATCGTGCCCGCCCTGTG
GATTCTCTATATCCGCCGCAACGTCAGCGATCCGGACATCTATACGGCCACGCGCCGCGCCCGCGACGAAGGCCGCGTGT
CGGGCCACTTCCTCGAGATCTTCTCGCCGCCGCACCTGCGCGCGACGCTGTTCGGCAGCGCGCTGTGCACCGGCATGCTC
GGCGGCTACTACGCGATCACGACGTGGCTGCCCACCTATCTCAAGACTGTGCGCCACCTGTCGGTGTTCAACACGAGCGG
CTATCTGGTCGTGCTGATCGTCGGCTCGTTCGTCGGCTACGTGGTCGGCGCGATCCTGTCCGACCGGCTCGGCCGCCGCG
CGTCCTTCATCCTGTTCGCGGTCGGCTCGTTCTCGCTTGGCATGGCGTACACGATGCTGCCGATCACCGATACCGCGATG
CTGCTGCTCGGCTTTCCACTCGGCATCGTCGTGCAGGGCATCTTCGCCGGCGTCGGCGCGTATCTGTCGGAGCTGTATCC
GGGCGCGATCCGCGGCTCGGGCCAGGGCTTCTGCTACAACCTCGGCCGCGGGCTCGGTTCGTTCTTTCCGATCCTCGTCG
GCGCGCTGTCGCAATCGATGTCGCTCGTGAAGGCGATCGGCCTCGTCGCGGGCGGCGGCTATCTGCTGGTGATCGTCGCG
GCGCTCGTGCTGCCGGAAACGCGCGGCAAGTCGCTCGTCGACGATCCGGCCGTCGCGTCGTGA

Upstream 100 bases:

>100_bases
CACAAACCTGCATCCGCCTTTTTGGCATGCCGGAGCGCGCCCGTAAAATAACCGCGACGCGGTAGCGCGGGACGAGACAA
GACGAGAGGGGGCGGCAAGC

Downstream 100 bases:

>100_bases
GCCACCGCCTCGTTCCGGACACCGCATGCACGTGATCGTTCTCGGCGCCGGCGTGATCGGCGTCACCACCGCCTGGCACC
TGCGCGAAGCAGGCTGCGAC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MQAFQWFNELSTRERRTLYAGFGGYAVDAFDFMIYSFLIPTLIATWGMTKSEAGMIATSSLISSAIGGWVAGILADRYGR
VRVLQWTIATFALFTCLSGFTHSFWQLLATRTLQGFGFGGEWSVVTIMMAETIRSPEHRAKAVGTVQSSWSFGWGAAAIL
YWAFFALLPEQVAWRACFWIGIVPALWILYIRRNVSDPDIYTATRRARDEGRVSGHFLEIFSPPHLRATLFGSALCTGML
GGYYAITTWLPTYLKTVRHLSVFNTSGYLVVLIVGSFVGYVVGAILSDRLGRRASFILFAVGSFSLGMAYTMLPITDTAM
LLLGFPLGIVVQGIFAGVGAYLSELYPGAIRGSGQGFCYNLGRGLGSFFPILVGALSQSMSLVKAIGLVAGGGYLLVIVA
ALVLPETRGKSLVDDPAVAS

Sequences:

>Translated_420_residues
MQAFQWFNELSTRERRTLYAGFGGYAVDAFDFMIYSFLIPTLIATWGMTKSEAGMIATSSLISSAIGGWVAGILADRYGR
VRVLQWTIATFALFTCLSGFTHSFWQLLATRTLQGFGFGGEWSVVTIMMAETIRSPEHRAKAVGTVQSSWSFGWGAAAIL
YWAFFALLPEQVAWRACFWIGIVPALWILYIRRNVSDPDIYTATRRARDEGRVSGHFLEIFSPPHLRATLFGSALCTGML
GGYYAITTWLPTYLKTVRHLSVFNTSGYLVVLIVGSFVGYVVGAILSDRLGRRASFILFAVGSFSLGMAYTMLPITDTAM
LLLGFPLGIVVQGIFAGVGAYLSELYPGAIRGSGQGFCYNLGRGLGSFFPILVGALSQSMSLVKAIGLVAGGGYLLVIVA
ALVLPETRGKSLVDDPAVAS
>Mature_420_residues
MQAFQWFNELSTRERRTLYAGFGGYAVDAFDFMIYSFLIPTLIATWGMTKSEAGMIATSSLISSAIGGWVAGILADRYGR
VRVLQWTIATFALFTCLSGFTHSFWQLLATRTLQGFGFGGEWSVVTIMMAETIRSPEHRAKAVGTVQSSWSFGWGAAAIL
YWAFFALLPEQVAWRACFWIGIVPALWILYIRRNVSDPDIYTATRRARDEGRVSGHFLEIFSPPHLRATLFGSALCTGML
GGYYAITTWLPTYLKTVRHLSVFNTSGYLVVLIVGSFVGYVVGAILSDRLGRRASFILFAVGSFSLGMAYTMLPITDTAM
LLLGFPLGIVVQGIFAGVGAYLSELYPGAIRGSGQGFCYNLGRGLGSFFPILVGALSQSMSLVKAIGLVAGGGYLLVIVA
ALVLPETRGKSLVDDPAVAS

Specific function: Probable uptake of 4-methylmuconolactone [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082404, Length=378, Percent_Identity=27.2486772486773, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI87082231, Length=442, Percent_Identity=24.4343891402715, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1790550, Length=438, Percent_Identity=25.5707762557078, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI87082159, Length=365, Percent_Identity=27.1232876712329, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI87081723, Length=337, Percent_Identity=25.8160237388724, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788942, Length=393, Percent_Identity=25.1908396946565, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1789152, Length=344, Percent_Identity=25.2906976744186, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI32564663, Length=443, Percent_Identity=24.3792325056433, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45594; Mature: 45594

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAFQWFNELSTRERRTLYAGFGGYAVDAFDFMIYSFLIPTLIATWGMTKSEAGMIATSS
CCHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
LISSAIGGWVAGILADRYGRVRVLQWTIATFALFTCLSGFTHSFWQLLATRTLQGFGFGG
HHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EWSVVTIMMAETIRSPEHRAKAVGTVQSSWSFGWGAAAILYWAFFALLPEQVAWRACFWI
CHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIVPALWILYIRRNVSDPDIYTATRRARDEGRVSGHFLEIFSPPHLRATLFGSALCTGML
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
GGYYAITTWLPTYLKTVRHLSVFNTSGYLVVLIVGSFVGYVVGAILSDRLGRRASFILFA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCHHHEEEEE
VGSFSLGMAYTMLPITDTAMLLLGFPLGIVVQGIFAGVGAYLSELYPGAIRGSGQGFCYN
CCCHHHHHHHEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
LGRGLGSFFPILVGALSQSMSLVKAIGLVAGGGYLLVIVAALVLPETRGKSLVDDPAVAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQAFQWFNELSTRERRTLYAGFGGYAVDAFDFMIYSFLIPTLIATWGMTKSEAGMIATSS
CCHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
LISSAIGGWVAGILADRYGRVRVLQWTIATFALFTCLSGFTHSFWQLLATRTLQGFGFGG
HHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EWSVVTIMMAETIRSPEHRAKAVGTVQSSWSFGWGAAAILYWAFFALLPEQVAWRACFWI
CHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIVPALWILYIRRNVSDPDIYTATRRARDEGRVSGHFLEIFSPPHLRATLFGSALCTGML
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
GGYYAITTWLPTYLKTVRHLSVFNTSGYLVVLIVGSFVGYVVGAILSDRLGRRASFILFA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCHHHEEEEE
VGSFSLGMAYTMLPITDTAMLLLGFPLGIVVQGIFAGVGAYLSELYPGAIRGSGQGFCYN
CCCHHHHHHHEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
LGRGLGSFFPILVGALSQSMSLVKAIGLVAGGGYLLVIVAALVLPETRGKSLVDDPAVAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9461415 [H]