Click here to switch to the map view.

The map label for this gene is 116688324

Identifier: 116688324

GI number: 116688324

Start: 340727

End: 342064

Strand: Direct

Name: 116688324

Synonym: Bcen2424_0300

Alternate gene names: NA

Gene position: 340727-342064 (Clockwise)

Preceding gene: 116688323

Following gene: 116688329

Centisome position: 9.78

GC content: 70.78

Gene sequence:

>1338_bases
ATGACCGTATTCGACCTCAACCGCGGCGCGCTCGCGCCGGTCGCCGACGAAGTCGACATCGTCGAGCTGCGCGTGACGGG
CGCCATTCCGCGCGAACTCGACGGCACGTTGCTGCGCAACGGTCCGAACCCGCCGGGTGGCCGCTTCGAAGGCAACGACA
TGCTGTCGTGGTGGCCGGAGGCCGCGATGCTGCACGCGATCGCGTTCGAAAACGGCCGCGCGGCCGGCTACCGGAACCGC
TGGGCGCGCACGCAGCGCTGGGCGGCCGTCCACGCGCCCGGGCAGGCGCCGCATCTGCCCGACACCAATCCGAACGTGAA
CGTGTTGCAGCATGCGGGCGAATTGCTCGCGCTGGCCGAGGGCGGCGCGCCGCTCGCGATCACCGCCGCGCTCGATTCGT
TCGGCGTGCCCGCGCGGCACGCGGGCTTCGACGGCGCGATGACCGCGCATCCGAAGGTCGACCCGGTGACCGGCGAGCTG
ATCCTGTTCCGCGCGGACTGGCGCGCTCCGTGGCTGCGCTACGGCGTGATCGACGCGATGGGTGTGAAGCGCATCGACGT
CGAGATCGAACTGGGCGCGCCGTCGATGATGCACGACCTCGCGATCACCGAAACCCGCAGCCTGCTGCTCGACCTGAACG
TCGGCTACGACTTCTCGCTGCTGAAGCAGGGCCACCGGATGCCGCTGCGCTGGCACGACGACCGGCCCGCGCGCATCGGC
GTGCTGCCGCGCCACGGCGGCGACGTGCGCTGGTTCGGCGTCGAGCCGTGCTTCATCCAGCACGTCGTGAACGCGTACGA
CTGCGATGCGTCGTGCATCGTGCTCGACGCGGTGCGCTATCCGTCGTTCCTGCGGCTCGACACGCGCACGGGCCGCTTCG
CGGACAACCCGGTCGGCGAGCTGTGGCGCTACGTGATCGACACCGCGAACGGGCTGATCGACGAAGGGCCGCTCGCCGAC
GGCGGCATCGAGCTGCCGCGCATCAACGAAAGCCGGACCGGGCGCAACTACCGCTATCTGTATGCGGTCGAGCAGCCGAA
TAACGCGGAAATGCGCGGCGTGATGCGTTTCGACCACGCGCGCGGCACGACGATGCACTACGCGGTGCCGGCCGGCGACC
AGAACGGCGAGCCGGTGTTCGTGCCGCGCCCGGGTGGCGCCGACGAGGACGACGGCTGGCTGCTGGTGATGGTCTACCGC
GCGGCGACGGATACGAGCGACGTCGTGATCCTCGATGCGCGCGCGATCGACGCGGGGCCGGTCGCGACCGTGCATCTGCC
GCGCCGCGTGCCGGCCGGGTTCCACGGCGCATGGGTGCCGTGCGAACGTCGAGCGTGA

Upstream 100 bases:

>100_bases
GATCGCCGGCTGGCCCGACGACGTGCGCGACCATGCGCTTGCCCTGGCGCGCGGCGATCTGCCGCCGGTCGCCGAAGACT
GCTGACGGAGCGCCGACGCG

Downstream 100 bases:

>100_bases
GCGGCGGCGCGCGTCACTGCGCGCGCAGCGCGTCGACGATCTTCAGCCGCGCGGCGCGCATCGCCGGCAGGAAGCCGCCG
ACGAGCCCCATCACGAGCGA

Product: carotenoid oxygenase

Products: NA

Alternate protein names: ACO; 8'-apo-beta-carotenal 15,15'-oxygenase; Diox1 [H]

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MTVFDLNRGALAPVADEVDIVELRVTGAIPRELDGTLLRNGPNPPGGRFEGNDMLSWWPEAAMLHAIAFENGRAAGYRNR
WARTQRWAAVHAPGQAPHLPDTNPNVNVLQHAGELLALAEGGAPLAITAALDSFGVPARHAGFDGAMTAHPKVDPVTGEL
ILFRADWRAPWLRYGVIDAMGVKRIDVEIELGAPSMMHDLAITETRSLLLDLNVGYDFSLLKQGHRMPLRWHDDRPARIG
VLPRHGGDVRWFGVEPCFIQHVVNAYDCDASCIVLDAVRYPSFLRLDTRTGRFADNPVGELWRYVIDTANGLIDEGPLAD
GGIELPRINESRTGRNYRYLYAVEQPNNAEMRGVMRFDHARGTTMHYAVPAGDQNGEPVFVPRPGGADEDDGWLLVMVYR
AATDTSDVVILDARAIDAGPVATVHLPRRVPAGFHGAWVPCERRA

Sequences:

>Translated_445_residues
MTVFDLNRGALAPVADEVDIVELRVTGAIPRELDGTLLRNGPNPPGGRFEGNDMLSWWPEAAMLHAIAFENGRAAGYRNR
WARTQRWAAVHAPGQAPHLPDTNPNVNVLQHAGELLALAEGGAPLAITAALDSFGVPARHAGFDGAMTAHPKVDPVTGEL
ILFRADWRAPWLRYGVIDAMGVKRIDVEIELGAPSMMHDLAITETRSLLLDLNVGYDFSLLKQGHRMPLRWHDDRPARIG
VLPRHGGDVRWFGVEPCFIQHVVNAYDCDASCIVLDAVRYPSFLRLDTRTGRFADNPVGELWRYVIDTANGLIDEGPLAD
GGIELPRINESRTGRNYRYLYAVEQPNNAEMRGVMRFDHARGTTMHYAVPAGDQNGEPVFVPRPGGADEDDGWLLVMVYR
AATDTSDVVILDARAIDAGPVATVHLPRRVPAGFHGAWVPCERRA
>Mature_444_residues
TVFDLNRGALAPVADEVDIVELRVTGAIPRELDGTLLRNGPNPPGGRFEGNDMLSWWPEAAMLHAIAFENGRAAGYRNRW
ARTQRWAAVHAPGQAPHLPDTNPNVNVLQHAGELLALAEGGAPLAITAALDSFGVPARHAGFDGAMTAHPKVDPVTGELI
LFRADWRAPWLRYGVIDAMGVKRIDVEIELGAPSMMHDLAITETRSLLLDLNVGYDFSLLKQGHRMPLRWHDDRPARIGV
LPRHGGDVRWFGVEPCFIQHVVNAYDCDASCIVLDAVRYPSFLRLDTRTGRFADNPVGELWRYVIDTANGLIDEGPLADG
GIELPRINESRTGRNYRYLYAVEQPNNAEMRGVMRFDHARGTTMHYAVPAGDQNGEPVFVPRPGGADEDDGWLLVMVYRA
ATDTSDVVILDARAIDAGPVATVHLPRRVPAGFHGAWVPCERRA

Specific function: Cleaves a number of carotenals and carotenols in the all-trans configuration at the 15-15' double bond producing retinal or retinol, respectively. Also shows activity toward lycopenals and the corresponding alcohols. Does not cleave beta- carotene or lyco

COG id: COG3670

COG function: function code Q; Lignostilbene-alpha,beta-dioxygenase and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carotenoid oxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004294 [H]

Pfam domain/function: PF03055 RPE65 [H]

EC number: =1.14.99.41 [H]

Molecular weight: Translated: 48935; Mature: 48804

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVFDLNRGALAPVADEVDIVELRVTGAIPRELDGTLLRNGPNPPGGRFEGNDMLSWWPE
CEEEECCCCCCCCCCCCCEEEEEEEECCCCCCCCCCEEECCCCCCCCCCCCCCCHHHCCH
AAMLHAIAFENGRAAGYRNRWARTQRWAAVHAPGQAPHLPDTNPNVNVLQHAGELLALAE
HHEEEEEEECCCCCCCCHHHHHHHHCEEEEECCCCCCCCCCCCCCHHHHHHCCCEEEEEC
GGAPLAITAALDSFGVPARHAGFDGAMTAHPKVDPVTGELILFRADWRAPWLRYGVIDAM
CCCCEEEEEEHHHCCCCHHHCCCCCCEECCCCCCCCCCEEEEEEECCCCCHHHHCCHHHC
GVKRIDVEIELGAPSMMHDLAITETRSLLLDLNVGYDFSLLKQGHRMPLRWHDDRPARIG
CEEEEEEEEEECCCHHHHHHHHCCCEEEEEEECCCCCHHHHHCCCCCCEEECCCCCCEEE
VLPRHGGDVRWFGVEPCFIQHVVNAYDCDASCIVLDAVRYPSFLRLDTRTGRFADNPVGE
EEECCCCCEEEEECCHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCHHH
LWRYVIDTANGLIDEGPLADGGIELPRINESRTGRNYRYLYAVEQPNNAEMRGVMRFDHA
HHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCCCCEEEEEEEECCCCCCEEEEEEECCC
RGTTMHYAVPAGDQNGEPVFVPRPGGADEDDGWLLVMVYRAATDTSDVVILDARAIDAGP
CCCEEEEEECCCCCCCCEEEEECCCCCCCCCCEEEEEEEECCCCCCCEEEEEEEECCCCC
VATVHLPRRVPAGFHGAWVPCERRA
EEEEEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TVFDLNRGALAPVADEVDIVELRVTGAIPRELDGTLLRNGPNPPGGRFEGNDMLSWWPE
EEEECCCCCCCCCCCCCEEEEEEEECCCCCCCCCCEEECCCCCCCCCCCCCCCHHHCCH
AAMLHAIAFENGRAAGYRNRWARTQRWAAVHAPGQAPHLPDTNPNVNVLQHAGELLALAE
HHEEEEEEECCCCCCCCHHHHHHHHCEEEEECCCCCCCCCCCCCCHHHHHHCCCEEEEEC
GGAPLAITAALDSFGVPARHAGFDGAMTAHPKVDPVTGELILFRADWRAPWLRYGVIDAM
CCCCEEEEEEHHHCCCCHHHCCCCCCEECCCCCCCCCCEEEEEEECCCCCHHHHCCHHHC
GVKRIDVEIELGAPSMMHDLAITETRSLLLDLNVGYDFSLLKQGHRMPLRWHDDRPARIG
CEEEEEEEEEECCCHHHHHHHHCCCEEEEEEECCCCCHHHHHCCCCCCEEECCCCCCEEE
VLPRHGGDVRWFGVEPCFIQHVVNAYDCDASCIVLDAVRYPSFLRLDTRTGRFADNPVGE
EEECCCCCEEEEECCHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCHHH
LWRYVIDTANGLIDEGPLADGGIELPRINESRTGRNYRYLYAVEQPNNAEMRGVMRFDHA
HHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCCCCEEEEEEEECCCCCCEEEEEEECCC
RGTTMHYAVPAGDQNGEPVFVPRPGGADEDDGWLLVMVYRAATDTSDVVILDARAIDAGP
CCCEEEEEECCCCCCCCEEEEECCCCCCCCCCEEEEEEEECCCCCCCEEEEEEEECCCCC
VATVHLPRRVPAGFHGAWVPCERRA
EEEEEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]