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The map label for this gene is gst [C]

Identifier: 116688322

GI number: 116688322

Start: 339188

End: 339952

Strand: Direct

Name: gst [C]

Synonym: Bcen2424_0298

Alternate gene names: 116688322

Gene position: 339188-339952 (Clockwise)

Preceding gene: 116688317

Following gene: 116688323

Centisome position: 9.74

GC content: 69.54

Gene sequence:

>765_bases
ATGACTGCTCGTTCAACTTCTGTGGAATTCCCGATGTCCCCGATCCTTCTCTACGGTATTCCCGCCGGCTGCTCGTTCGG
CTCGATCGTCGCGCTCGAATGGACCGGCCGCCCGTACCGGCTGTCGCGCATCACGATGCCGGGCGCCGTGACGAGCGACG
CGTTCCTCGCGCTGAACCCCGTCGCCGAGACGCCGGCGTTCGTCACGGCGAACGGCGACGTGCTGACCGAAAGCATCGCG
ATCCTCGGCCATATCGGCGCGCAGGCGCTCGACCGCGGCCTCGCGTTTCGGCAGGGCAGCGCGGATTTCGACCGGCTGAA
CCGGATGCTGGCGTGGCTGAACACGACGTTCTTCAACGCGTTCGGCGCGCTCTGGTACGTGTACGAACACGACACCGAAG
GCGCGGAGAAAGCGGCGTTGCAGGCGTACGGCCGCGGCAAGGTGCTGAAGGCGCACCGGCAGCTCGAAGCGCTGCTCGAG
CGCGGCGAAGGCCCGTGGCTGCTGGGCGCGCGACGCACGCTGGCCGATGCGTACTTCACGGGAATCGCGCGCTGGGCCGA
CTATCACGCGGTGTTCGAGCGCGATGCGTTCCCGCGCGTCGCCGCGCTGCGCGCGCGGCTTGCCGACGATGCCGGCGTGC
AGTTCGCGCACGCGATCGAGGAGAACCTGCCGCCGCCGGCGTCTTCCGCGTTCGAAGGGCATGTGTCGCTCGACGACGCG
CTGGCCAGCGCGCGCGGCATCGTGGCGTCGGCGCGGGCGGTCTGA

Upstream 100 bases:

>100_bases
CGAACAGGTAGAGATCGTTCAGATTCATTTCCAGCGTCCACATGGAGAAACGACGGGTTTCGATTTTAGCGGCTACTGCG
CCATCGTTCGCCATGGGAGC

Downstream 100 bases:

>100_bases
TCGGCAAGCCGGTCGCTCCACAGGACGGAACATGCTGGCGACAATTTTTACCCGGATAATATTGACATCCAATTAATACC
CGGATAAAAATAGCGTCATT

Product: glutathione S-transferase domain-containing protein

Products: HX; R-S-Glutathione; S-(2,4-dinitrophenyl)glutathione [C]

Alternate protein names: Glutathione S-Transferase Domain Protein; Glutathione S-Transferase Domain-Containing Protein; Glutathione-S-Transferase; Glutathione S-Transferase-Like Protein; Glutathione S-Transferase Protein; Glutathione Transferase Protein; Glutathione S-Transferase Domain; Glutathione S-Transferase Family Protein

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MTARSTSVEFPMSPILLYGIPAGCSFGSIVALEWTGRPYRLSRITMPGAVTSDAFLALNPVAETPAFVTANGDVLTESIA
ILGHIGAQALDRGLAFRQGSADFDRLNRMLAWLNTTFFNAFGALWYVYEHDTEGAEKAALQAYGRGKVLKAHRQLEALLE
RGEGPWLLGARRTLADAYFTGIARWADYHAVFERDAFPRVAALRARLADDAGVQFAHAIEENLPPPASSAFEGHVSLDDA
LASARGIVASARAV

Sequences:

>Translated_254_residues
MTARSTSVEFPMSPILLYGIPAGCSFGSIVALEWTGRPYRLSRITMPGAVTSDAFLALNPVAETPAFVTANGDVLTESIA
ILGHIGAQALDRGLAFRQGSADFDRLNRMLAWLNTTFFNAFGALWYVYEHDTEGAEKAALQAYGRGKVLKAHRQLEALLE
RGEGPWLLGARRTLADAYFTGIARWADYHAVFERDAFPRVAALRARLADDAGVQFAHAIEENLPPPASSAFEGHVSLDDA
LASARGIVASARAV
>Mature_253_residues
TARSTSVEFPMSPILLYGIPAGCSFGSIVALEWTGRPYRLSRITMPGAVTSDAFLALNPVAETPAFVTANGDVLTESIAI
LGHIGAQALDRGLAFRQGSADFDRLNRMLAWLNTTFFNAFGALWYVYEHDTEGAEKAALQAYGRGKVLKAHRQLEALLER
GEGPWLLGARRTLADAYFTGIARWADYHAVFERDAFPRVAALRARLADDAGVQFAHAIEENLPPPASSAFEGHVSLDDAL
ASARGIVASARAV

Specific function: Conjugation Of Reduced Glutathione To A Wide Number Of Exogenous And Endogenous Hydrophobic Electrophiles. [C]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787923, Length=206, Percent_Identity=26.2135922330097, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.5.1.18 [C]

Molecular weight: Translated: 27410; Mature: 27279

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARSTSVEFPMSPILLYGIPAGCSFGSIVALEWTGRPYRLSRITMPGAVTSDAFLALNP
CCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCEEEECC
VAETPAFVTANGDVLTESIAILGHIGAQALDRGLAFRQGSADFDRLNRMLAWLNTTFFNA
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCHHHCCCCCCHHHHHHHHHHHHHHHHHH
FGALWYVYEHDTEGAEKAALQAYGRGKVLKAHRQLEALLERGEGPWLLGARRTLADAYFT
HHHEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHH
GIARWADYHAVFERDAFPRVAALRARLADDAGVQFAHAIEENLPPPASSAFEGHVSLDDA
HHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHH
LASARGIVASARAV
HHHHHHHHHHCCCC
>Mature Secondary Structure 
TARSTSVEFPMSPILLYGIPAGCSFGSIVALEWTGRPYRLSRITMPGAVTSDAFLALNP
CCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCEEEECC
VAETPAFVTANGDVLTESIAILGHIGAQALDRGLAFRQGSADFDRLNRMLAWLNTTFFNA
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCHHHCCCCCCHHHHHHHHHHHHHHHHHH
FGALWYVYEHDTEGAEKAALQAYGRGKVLKAHRQLEALLERGEGPWLLGARRTLADAYFT
HHHEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHH
GIARWADYHAVFERDAFPRVAALRARLADDAGVQFAHAIEENLPPPASSAFEGHVSLDDA
HHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHH
LASARGIVASARAV
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RX; Glutathione; 1-chloro-2,4-dinitrobenzene; reduced glutathione [C]

Specific reaction: RX + Glutathione = HX + R-S-Glutathione 1-chloro-2,4-dinitrobenzene + reduced glutathione = S-(2,4-dinitrophenyl)glutathione [C]

General reaction: Aryl group transfer [C]

Inhibitor: Cd2+; CibacronBlue; Co2+; Cu2+; Hematin; Hg2+; Ni2+; Sulfophthaleins; Tributyl tinacetate; Triethyl tinbromide; Zn2+ [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA