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The map label for this gene is ycbL [H]

Identifier: 116688309

GI number: 116688309

Start: 327430

End: 328074

Strand: Reverse

Name: ycbL [H]

Synonym: Bcen2424_0285

Alternate gene names: 116688309

Gene position: 328074-327430 (Counterclockwise)

Preceding gene: 116688313

Following gene: 116688308

Centisome position: 9.42

GC content: 66.51

Gene sequence:

>645_bases
ATGAAAGTCACGCTCATTCCGGTCACGCCGTTCCAGCAGAACTGCTCGCTGCTCGTCTGCGAGAAGACGGGCCGCGCCGC
CGTCGTCGATCCGGGCGGCGATCTCGACCGCATCGAACAGGAAGTCGCGCGGCAGAACGTGCAGGTCGAGAAGGTGCTGC
TCACGCACGGGCACATCGACCACTGCGCGGGCGCGAAAACGCTCGCGACGCGCTACGGCGTGCCGATCGAGGGGCCGCAG
GAAGAGGAACGCTTCTGGATCGAGAAGCTGCCGATGCAGAGCGAGCGCTTCGGCTTTCCGGCCGCCGACGTCTTCGAGCC
CGACCAGTGGCTGAACGACGGCGACACCGTGCGGTTCGGCGACGAGACGCTCGAGGTCTATCACTGCCCGGGCCACACGC
CCGGCCACGTCGTGTTCTTCAGCCGCGCACATCGCGTCGCGATCGTCGGCGACGTGCTGTTCGCGGGCTCGATCGGCCGG
ACCGATTTCCCGCGCGGCAATCACGAGGATCTCGTCCGTTCGATCAAGGAAAAACTGTGGCCGCTCGGCGACGACGTCAC
GTTCGTGCCCGGCCACGGCCCAGTGTCGACGTTCGGCGACGAGCGCCGCACGAACCCGTTCGTGTCCGACAAGGTATTCG
GATGA

Upstream 100 bases:

>100_bases
TCCGGGAATGCCCTGATCGGCACGCCGCCGCATGCATCGCACGCCCGGCAGCCCGTACGCGCGACCGGTACAATCGCTCC
TTTTAGCCGCCGGTGCACCC

Downstream 100 bases:

>100_bases
ACCAGACCGCCATCCCGGAAATTTACGTCAGCACCGACGTCGAGGCCGACGGCCCGATTCCCGGCCCGCACTCGATGCTG
AGCTTCGCGTCGGCCGCCTA

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MKVTLIPVTPFQQNCSLLVCEKTGRAAVVDPGGDLDRIEQEVARQNVQVEKVLLTHGHIDHCAGAKTLATRYGVPIEGPQ
EEERFWIEKLPMQSERFGFPAADVFEPDQWLNDGDTVRFGDETLEVYHCPGHTPGHVVFFSRAHRVAIVGDVLFAGSIGR
TDFPRGNHEDLVRSIKEKLWPLGDDVTFVPGHGPVSTFGDERRTNPFVSDKVFG

Sequences:

>Translated_214_residues
MKVTLIPVTPFQQNCSLLVCEKTGRAAVVDPGGDLDRIEQEVARQNVQVEKVLLTHGHIDHCAGAKTLATRYGVPIEGPQ
EEERFWIEKLPMQSERFGFPAADVFEPDQWLNDGDTVRFGDETLEVYHCPGHTPGHVVFFSRAHRVAIVGDVLFAGSIGR
TDFPRGNHEDLVRSIKEKLWPLGDDVTFVPGHGPVSTFGDERRTNPFVSDKVFG
>Mature_214_residues
MKVTLIPVTPFQQNCSLLVCEKTGRAAVVDPGGDLDRIEQEVARQNVQVEKVLLTHGHIDHCAGAKTLATRYGVPIEGPQ
EEERFWIEKLPMQSERFGFPAADVFEPDQWLNDGDTVRFGDETLEVYHCPGHTPGHVVFFSRAHRVAIVGDVLFAGSIGR
TDFPRGNHEDLVRSIKEKLWPLGDDVTFVPGHGPVSTFGDERRTNPFVSDKVFG

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=206, Percent_Identity=30.0970873786408, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1787158, Length=212, Percent_Identity=55.6603773584906, Blast_Score=262, Evalue=1e-71,
Organism=Caenorhabditis elegans, GI17538952, Length=195, Percent_Identity=30.7692307692308, Blast_Score=87, Evalue=7e-18,
Organism=Drosophila melanogaster, GI221330176, Length=202, Percent_Identity=27.2277227722772, Blast_Score=71, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 23817; Mature: 23817

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVTLIPVTPFQQNCSLLVCEKTGRAAVVDPGGDLDRIEQEVARQNVQVEKVLLTHGHID
CEEEEEECCCCCCCCCEEEEECCCCEEEECCCCCHHHHHHHHHHCCCEEEEEEEECCCHH
HCAGAKTLATRYGVPIEGPQEEERFWIEKLPMQSERFGFPAADVFEPDQWLNDGDTVRFG
HHCCCHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHHCCCCCCCCCCCHHHCCCCCEEEEC
DETLEVYHCPGHTPGHVVFFSRAHRVAIVGDVLFAGSIGRTDFPRGNHEDLVRSIKEKLW
CCEEEEEECCCCCCCEEEEEECCCEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHC
PLGDDVTFVPGHGPVSTFGDERRTNPFVSDKVFG
CCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKVTLIPVTPFQQNCSLLVCEKTGRAAVVDPGGDLDRIEQEVARQNVQVEKVLLTHGHID
CEEEEEECCCCCCCCCEEEEECCCCEEEECCCCCHHHHHHHHHHCCCEEEEEEEECCCHH
HCAGAKTLATRYGVPIEGPQEEERFWIEKLPMQSERFGFPAADVFEPDQWLNDGDTVRFG
HHCCCHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHHCCCCCCCCCCCHHHCCCCCEEEEC
DETLEVYHCPGHTPGHVVFFSRAHRVAIVGDVLFAGSIGRTDFPRGNHEDLVRSIKEKLW
CCEEEEEECCCCCCCEEEEEECCCEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHC
PLGDDVTFVPGHGPVSTFGDERRTNPFVSDKVFG
CCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]