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The map label for this gene is benK [H]

Identifier: 116688186

GI number: 116688186

Start: 180076

End: 181479

Strand: Direct

Name: benK [H]

Synonym: Bcen2424_0162

Alternate gene names: 116688186

Gene position: 180076-181479 (Clockwise)

Preceding gene: 116688185

Following gene: 116688187

Centisome position: 5.17

GC content: 65.31

Gene sequence:

>1404_bases
TTGACGACACCCCTCAATGTCCGGGAGGAGCTGGCGCACGCGCGCATCGGCCGCTTCCATCTACGCTTCGCGGTACTCGT
CGCCTTCATCATGTTCTTCGACGGCTACGATCTCTTTAACGCCGCCTATGTGATTCCGCTCGTTCGACACGAATGGCAGC
CGTCGCCGACGATGATCGGGATCATGCTGTCAAGCGGCATCGTCGGGCTGTCGATTGGCTCGGTGCTGCAAGGCCTGATC
GCGGATCGGATCGGCCGGCGCAAGGTGATGCTCGGCGCGCTGTGGACTCTGACGCTGTCGAGCGGCCTGCTTGCTACCGT
CGTCCACTCGGCGGAGAGCTTCGCGCTCGCGCGTCTCGTCATGGGCACCGCGCTCGGTATGGTCACGCCGCTCGCGCTCA
CGTGCATCAACGAGTGGGCGCCGCGCCGCAACGCGAATACGTTCGCCACCTGGGTCTTTCAGTTTGGCTTTTCGGCGGGC
GGCATCTTCGCGGGCATCGCGGGTCTCACGCTCACGCCGCATCTGGGCTGGCAGTCGCTTTACTTCGTCGGCGTGTTGTC
GGCGCTCGTCGCGGCGGCGGCGATGAAATGGCTGCCTGAATCCGCGCAATATCTCGCGCTGCGCGGCCGCACCGACGACG
TGCTCGCGCTGCTGAAAGCGGTTCGTCCCGAACGCGAAGCGGTTTATCGCGACGCCCACATTCAACTGATGCGCGCGACG
TCGCGGCCCGGTTCGATCAGCGATCTGCTGTCCGCCGAATATCGCCGTAACACGCTGGTGCACTGGATTGCGGGCGCGTT
GAGCCTGTTCTGCATCCACGGCCTGACCGGTTGGCTGCCGACGATGGTCGTGAACAAGGGCGGTGGCGTGTCGTCGGCGT
TCGGCTACGGCACGGTGGTGATGATCGCGTCGGTGTTCGGCGGGATCTCGATGGGGTGGGTGGCTGACCGCATGCACAGC
CGCATCCGCGCGATGGTGGTCGGCTACATCGTCGCGGCGCTCTTCATGGCAGGCCTCGCGCTCACGCTCGGCAAGACGGG
CTCGATGGTGCTGGTCGCGTGCGTTGGCTTCTTCATCTTCGGCGCGCAGGCGATCATGAATAACTATCAGGCGATGTGTT
ACCGCACGGAAATCCGCGGCACCGGCATGGGCGTTGCGGTGGGGTTGAACCGGATTGGCGGGATACTCGGGCCTGTTATC
GTGGGTGTCGTCGCTTCGCTCAATCCCGACCCTCTGTGGACGTTCGCGGTGTTCACGGGCGCGCTGATCCTCGCCGCGGG
CGTGATCGCGCTCGGTAAGACGGAGATCGCCGCGTTGCCCGCTTCGTGGCCCAACGCCGCGACGCAGCAGGACGACGAAG
CGCTGCCTGCGGGCGCGCGACACGATCACGGCGTTGCAGGCTAA

Upstream 100 bases:

>100_bases
AACGCACCGCGCCGCATCGCCTCGCAACGGCGATGTTTGACTTACCCGCCCGCCGGCATAAGGCGGCATCGGTCGAAAAT
CAGAAAACACGGAGACAACC

Downstream 100 bases:

>100_bases
GCGCAAACGCGCGAACATTCGGATCGTTTCGAATCTCAGGGCCGCCCGACGAGGCGGCCTTTTGCATGGAGACGCGTGAG
ATGCGCTTTAACAGACTGGA

Product: major facilitator transporter

Products: Proton [Cytoplasm]; 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MTTPLNVREELAHARIGRFHLRFAVLVAFIMFFDGYDLFNAAYVIPLVRHEWQPSPTMIGIMLSSGIVGLSIGSVLQGLI
ADRIGRRKVMLGALWTLTLSSGLLATVVHSAESFALARLVMGTALGMVTPLALTCINEWAPRRNANTFATWVFQFGFSAG
GIFAGIAGLTLTPHLGWQSLYFVGVLSALVAAAAMKWLPESAQYLALRGRTDDVLALLKAVRPEREAVYRDAHIQLMRAT
SRPGSISDLLSAEYRRNTLVHWIAGALSLFCIHGLTGWLPTMVVNKGGGVSSAFGYGTVVMIASVFGGISMGWVADRMHS
RIRAMVVGYIVAALFMAGLALTLGKTGSMVLVACVGFFIFGAQAIMNNYQAMCYRTEIRGTGMGVAVGLNRIGGILGPVI
VGVVASLNPDPLWTFAVFTGALILAAGVIALGKTEIAALPASWPNAATQQDDEALPAGARHDHGVAG

Sequences:

>Translated_467_residues
MTTPLNVREELAHARIGRFHLRFAVLVAFIMFFDGYDLFNAAYVIPLVRHEWQPSPTMIGIMLSSGIVGLSIGSVLQGLI
ADRIGRRKVMLGALWTLTLSSGLLATVVHSAESFALARLVMGTALGMVTPLALTCINEWAPRRNANTFATWVFQFGFSAG
GIFAGIAGLTLTPHLGWQSLYFVGVLSALVAAAAMKWLPESAQYLALRGRTDDVLALLKAVRPEREAVYRDAHIQLMRAT
SRPGSISDLLSAEYRRNTLVHWIAGALSLFCIHGLTGWLPTMVVNKGGGVSSAFGYGTVVMIASVFGGISMGWVADRMHS
RIRAMVVGYIVAALFMAGLALTLGKTGSMVLVACVGFFIFGAQAIMNNYQAMCYRTEIRGTGMGVAVGLNRIGGILGPVI
VGVVASLNPDPLWTFAVFTGALILAAGVIALGKTEIAALPASWPNAATQQDDEALPAGARHDHGVAG
>Mature_466_residues
TTPLNVREELAHARIGRFHLRFAVLVAFIMFFDGYDLFNAAYVIPLVRHEWQPSPTMIGIMLSSGIVGLSIGSVLQGLIA
DRIGRRKVMLGALWTLTLSSGLLATVVHSAESFALARLVMGTALGMVTPLALTCINEWAPRRNANTFATWVFQFGFSAGG
IFAGIAGLTLTPHLGWQSLYFVGVLSALVAAAAMKWLPESAQYLALRGRTDDVLALLKAVRPEREAVYRDAHIQLMRATS
RPGSISDLLSAEYRRNTLVHWIAGALSLFCIHGLTGWLPTMVVNKGGGVSSAFGYGTVVMIASVFGGISMGWVADRMHSR
IRAMVVGYIVAALFMAGLALTLGKTGSMVLVACVGFFIFGAQAIMNNYQAMCYRTEIRGTGMGVAVGLNRIGGILGPVIV
GVVASLNPDPLWTFAVFTGALILAAGVIALGKTEIAALPASWPNAATQQDDEALPAGARHDHGVAG

Specific function: Probable uptake of benzoate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI24308167, Length=433, Percent_Identity=24.9422632794457, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI213021148, Length=479, Percent_Identity=24.4258872651357, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI7662270, Length=340, Percent_Identity=23.8235294117647, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI216548223, Length=332, Percent_Identity=24.6987951807229, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI262399383, Length=265, Percent_Identity=24.5283018867925, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI166064021, Length=355, Percent_Identity=27.887323943662, Blast_Score=69, Evalue=9e-12,
Organism=Escherichia coli, GI87081723, Length=387, Percent_Identity=26.0981912144703, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082404, Length=377, Percent_Identity=22.5464190981432, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1788074, Length=364, Percent_Identity=26.3736263736264, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87082159, Length=387, Percent_Identity=24.2894056847545, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1788068, Length=450, Percent_Identity=25.1111111111111, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI32564663, Length=423, Percent_Identity=23.8770685579196, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI19922874, Length=401, Percent_Identity=21.6957605985037, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24640198, Length=498, Percent_Identity=19.8795180722892, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24640196, Length=498, Percent_Identity=19.8795180722892, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24640200, Length=498, Percent_Identity=19.8795180722892, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19922616, Length=420, Percent_Identity=24.5238095238095, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004746
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49676; Mature: 49545

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPLNVREELAHARIGRFHLRFAVLVAFIMFFDGYDLFNAAYVIPLVRHEWQPSPTMIG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCEEE
IMLSSGIVGLSIGSVLQGLIADRIGRRKVMLGALWTLTLSSGLLATVVHSAESFALARLV
HHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
MGTALGMVTPLALTCINEWAPRRNANTFATWVFQFGFSAGGIFAGIAGLTLTPHLGWQSL
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHCEECCCCCHHHH
YFVGVLSALVAAAAMKWLPESAQYLALRGRTDDVLALLKAVRPEREAVYRDAHIQLMRAT
HHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHEECC
SRPGSISDLLSAEYRRNTLVHWIAGALSLFCIHGLTGWLPTMVVNKGGGVSSAFGYGTVV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHH
MIASVFGGISMGWVADRMHSRIRAMVVGYIVAALFMAGLALTLGKTGSMVLVACVGFFIF
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
GAQAIMNNYQAMCYRTEIRGTGMGVAVGLNRIGGILGPVIVGVVASLNPDPLWTFAVFTG
HHHHHHCCHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
ALILAAGVIALGKTEIAALPASWPNAATQQDDEALPAGARHDHGVAG
HHHHHHHHHHCCCHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TTPLNVREELAHARIGRFHLRFAVLVAFIMFFDGYDLFNAAYVIPLVRHEWQPSPTMIG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCEEE
IMLSSGIVGLSIGSVLQGLIADRIGRRKVMLGALWTLTLSSGLLATVVHSAESFALARLV
HHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
MGTALGMVTPLALTCINEWAPRRNANTFATWVFQFGFSAGGIFAGIAGLTLTPHLGWQSL
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHCEECCCCCHHHH
YFVGVLSALVAAAAMKWLPESAQYLALRGRTDDVLALLKAVRPEREAVYRDAHIQLMRAT
HHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHEECC
SRPGSISDLLSAEYRRNTLVHWIAGALSLFCIHGLTGWLPTMVVNKGGGVSSAFGYGTVV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHH
MIASVFGGISMGWVADRMHSRIRAMVVGYIVAALFMAGLALTLGKTGSMVLVACVGFFIF
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
GAQAIMNNYQAMCYRTEIRGTGMGVAVGLNRIGGILGPVIVGVVASLNPDPLWTFAVFTG
HHHHHHCCHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
ALILAAGVIALGKTEIAALPASWPNAATQQDDEALPAGARHDHGVAG
HHHHHHHHHHCCCHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 3-(3-hydroxyphenyl)propionate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 3-(3-hydroxyphenyl)propionate [Periplasm] = Proton [Cytoplasm] + 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9294456 [H]