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The map label for this gene is pheC [H]

Identifier: 116688134

GI number: 116688134

Start: 112747

End: 113559

Strand: Reverse

Name: pheC [H]

Synonym: Bcen2424_0110

Alternate gene names: 116688134

Gene position: 113559-112747 (Counterclockwise)

Preceding gene: 116688139

Following gene: 116688133

Centisome position: 3.26

GC content: 65.44

Gene sequence:

>813_bases
ATGAAGACATTCGCCACGCTTGCCACGCTCGCTGCCGCTGCCGCGTTTTGCTGCGCCGCCGCGCACGCGCAGGGCACGAC
CACGCCGGCGCCCGCGAGCGCCGCTGCCGCCGGCTCGCGGCTCGACGACGTGCTCGCGCGCGGCGCGCTGCGCGTGTGCA
CGACGGGCGACTACAAGCCGTATTCGTACTATCGCGCGGACGGCCGCTTCGAGGGCATCGACATCGACATGGCGGAATCG
CTCGCGAAATCGCTCGGCGTGAAGACCGACTACGTGAAGACGAGCTGGTCGAACCTCACCAACGACTTCGTCGCGAAATG
CGACATCGCGGTAGGCGGCGTATCGACGACGCTCGAGCGCCAGAAGCGCGTGTTCTTCACGCAGCCGTACGTGGTCGACG
GCAAGACGCCGATCGTGCGCTGCGCGGATGCCGACAAGTACCAGACCGTCGCGCAGATCGACCGGCCCGAGACGCGGGTG
ATCGTGAATCCGGGCGGCACCAACGAGCGCTTCGCGAAGCAGTTCTTCACGCACGCGAACCTGACCGTCTTCCCGGACAA
CGTGACGATCTTCAAGCAGATCCTGGCGGGCAAGGCCGACGTGATGGTGACGGATGCGTCCGAGACGCTGCTGCAGCAAA
AGCTGAATCCGGGCCTTTGCTCGGTGCATCCGGACAAGCCGTTCCAGTTCGGAGAGAAGGCGTACATGGTGCCGCGCGGC
GACGTCACGTTCCAGCAGTACGTCGACCAGTGGCTGCATCTCGCGCTGTCCACCGGCGAGTACCAGGCGATTTCGGACAA
GTGGCTGAAGTAA

Upstream 100 bases:

>100_bases
GATCGGGCTGCGCATGCCGATGCGATGGCGGCCATATGACGCGCGCGATGGCTCCGTTATGATCGGACGCTCATATCCAA
CCGAACGAAGGAGGAGACCG

Downstream 100 bases:

>100_bases
GCTGACCCGCGCCGCGGCGGCCGATCATGGGCACTGACCCCGCGGCCGCCGCGCGCGCCGTTACACATTGCCGTCGCTGC
GCCGGGCCTTCCCGCGGCGC

Product: prephenate dehydratase

Products: NA

Alternate protein names: Prephenate dehydratase; Arogenate dehydratase [H]

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MKTFATLATLAAAAAFCCAAAHAQGTTTPAPASAAAAGSRLDDVLARGALRVCTTGDYKPYSYYRADGRFEGIDIDMAES
LAKSLGVKTDYVKTSWSNLTNDFVAKCDIAVGGVSTTLERQKRVFFTQPYVVDGKTPIVRCADADKYQTVAQIDRPETRV
IVNPGGTNERFAKQFFTHANLTVFPDNVTIFKQILAGKADVMVTDASETLLQQKLNPGLCSVHPDKPFQFGEKAYMVPRG
DVTFQQYVDQWLHLALSTGEYQAISDKWLK

Sequences:

>Translated_270_residues
MKTFATLATLAAAAAFCCAAAHAQGTTTPAPASAAAAGSRLDDVLARGALRVCTTGDYKPYSYYRADGRFEGIDIDMAES
LAKSLGVKTDYVKTSWSNLTNDFVAKCDIAVGGVSTTLERQKRVFFTQPYVVDGKTPIVRCADADKYQTVAQIDRPETRV
IVNPGGTNERFAKQFFTHANLTVFPDNVTIFKQILAGKADVMVTDASETLLQQKLNPGLCSVHPDKPFQFGEKAYMVPRG
DVTFQQYVDQWLHLALSTGEYQAISDKWLK
>Mature_270_residues
MKTFATLATLAAAAAFCCAAAHAQGTTTPAPASAAAAGSRLDDVLARGALRVCTTGDYKPYSYYRADGRFEGIDIDMAES
LAKSLGVKTDYVKTSWSNLTNDFVAKCDIAVGGVSTTLERQKRVFFTQPYVVDGKTPIVRCADADKYQTVAQIDRPETRV
IVNPGGTNERFAKQFFTHANLTVFPDNVTIFKQILAGKADVMVTDASETLLQQKLNPGLCSVHPDKPFQFGEKAYMVPRG
DVTFQQYVDQWLHLALSTGEYQAISDKWLK

Specific function: Forms alternative pathway for phenylalanine biosynthesis. Can catalyze two reactions:prephenate dehydratase and arogenate dehydratase. May have a role in chemotaxis or transport [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788228, Length=230, Percent_Identity=26.0869565217391, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787088, Length=227, Percent_Identity=25.1101321585903, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 1920 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1060 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 80 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015683
- InterPro:   IPR001638
- InterPro:   IPR018313 [H]

Pfam domain/function: PF00497 SBP_bac_3 [H]

EC number: =4.2.1.51; =4.2.1.91 [H]

Molecular weight: Translated: 29487; Mature: 29487

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: PS01039 SBP_BACTERIAL_3 ; PS00290 IG_MHC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTFATLATLAAAAAFCCAAAHAQGTTTPAPASAAAAGSRLDDVLARGALRVCTTGDYKP
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCC
YSYYRADGRFEGIDIDMAESLAKSLGVKTDYVKTSWSNLTNDFVAKCDIAVGGVSTTLER
CEEEECCCEECCCCCHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHEEEEECCHHHHHHH
QKRVFFTQPYVVDGKTPIVRCADADKYQTVAQIDRPETRVIVNPGGTNERFAKQFFTHAN
HHCEEEECCEEECCCCCEEEECCCCHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCC
LTVFPDNVTIFKQILAGKADVMVTDASETLLQQKLNPGLCSVHPDKPFQFGEKAYMVPRG
CEEECCCHHHHHHHHCCCCCEEEECHHHHHHHHHCCCCCEECCCCCCCCCCCEEEECCCC
DVTFQQYVDQWLHLALSTGEYQAISDKWLK
CCCHHHHHHHHHHHHHCCCCCHHHHHHCCC
>Mature Secondary Structure
MKTFATLATLAAAAAFCCAAAHAQGTTTPAPASAAAAGSRLDDVLARGALRVCTTGDYKP
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCC
YSYYRADGRFEGIDIDMAESLAKSLGVKTDYVKTSWSNLTNDFVAKCDIAVGGVSTTLER
CEEEECCCEECCCCCHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHEEEEECCHHHHHHH
QKRVFFTQPYVVDGKTPIVRCADADKYQTVAQIDRPETRVIVNPGGTNERFAKQFFTHAN
HHCEEEECCEEECCCCCEEEECCCCHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCC
LTVFPDNVTIFKQILAGKADVMVTDASETLLQQKLNPGLCSVHPDKPFQFGEKAYMVPRG
CEEECCCHHHHHHHHCCCCCEEEECHHHHHHHHHCCCCCEECCCCCCCCCCCEEEECCCC
DVTFQQYVDQWLHLALSTGEYQAISDKWLK
CCCHHHHHHHHHHHHHCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1733946; 10984043; 8515238; 7604006 [H]