Click here to switch to the map view.

The map label for this gene is namA [H]

Identifier: 116688096

GI number: 116688096

Start: 74288

End: 75400

Strand: Direct

Name: namA [H]

Synonym: Bcen2424_0072

Alternate gene names: 116688096

Gene position: 74288-75400 (Clockwise)

Preceding gene: 116688095

Following gene: 116688097

Centisome position: 2.13

GC content: 70.26

Gene sequence:

>1113_bases
ATGACTGCGCTGTTTTCCCCGTTCACGCTGCGCGGCGTGACCCTTCCGAACCGGATCGTGATTTCCCCGATGTGCCAGTA
CTCGGCCGAACGCGGCGAAGCGACCGACTGGCACATGATTCACCTCGGCCATCTCGCGCTGTCGGGCGCTGGGCTGCTGT
GCATCGAGGCGACCGCGGTGGAGCCCGACGGGCGCATCACGCATGGCGACCTCGGTCTGTGGGACGACGTGACCGAAGCC
GCGCTGAAGCCGGTGCTGGCCGCGATCCGCAAGCATTCGCCGATCCGCGTCGCGATGCAGCTGTCGCACGCGGGCCGCAA
GGCGTCGAGCGCGGCGCCGTGGGAGGGCGGCCAGCTCGTGCCGGTCGCCGACGGCGGCTGGCTGCCGCACGGGCCGTCGG
CCGTGCCGCACAAGGACGGCGAGACGCCGCCGCTCGCGCTCGATGCGGCGGGCCTGAACCGCATCCGCGAAGCCTTTGCC
GCATCGGCCAGGCGTGCCGCACGGCTCGGCATCGATGCGATCGAAGTGCACGCGGCGCACGGCTACCTGCTGCATCAGTT
CCTGTCGCCGCTCGCGAACCGGCGCACCGACGAATACGGCGGCTCGCGCGAAAACCGGATGCGGTTTCCGCTCGAGATCT
TCGAGATCGTGCGTGCCGCGTTTCCGGAAGACCGGCCGGTCGGCGTGCGCGTGTCCGCGACCGACTGGGTCGAAGGCGGC
TGGGAACTCGACGATACGATCGCGTTCGCACATGAACTGAAGCGCCGCGGCTGTGACTGGATCGACGTGTCGTCCGGCGG
CGTGTCGCCGCTGCAGAAGATTCCGCTGTCGCCCGGCTACCAGGTGCCGTTCGCGCAGGCCGTGAAGCGGTCGGTCGGCA
TGCCGACGATCGCGGTCGGCCTGATCAACGAACCCGCGCACGCGAACCGGCTGATCGAGGCCGGCGATGCCGATTTCGTC
GCGATGGCGCGCGCGATGCTGTACGACCCGCGCTGGCCGTGGCACGCGGCGGCCGAACTCGGCGCGCAGGTGACGGCGCC
GCCGCAGTACTGGCGTTCGCAGCCGCGTGAGCACAAGGCGCTGTTCGGCGACGTCTCGTTCGGCCAGCGCTGA

Upstream 100 bases:

>100_bases
CGTACCTGACCATCCGCTTACTGCCGATGGCGCCGTCTGCACGCTTCCAGCCTGCGTGCTACGCTCGTCCGCTCTTTCCC
TTTCCTGGCGAGCGGCTTCC

Downstream 100 bases:

>100_bases
GCACATCGCGCAATATTGCGCGCGATGTTGAACGAAGCAATCTTGAACGTGTAGGATGCGGATGATTCGCCGCATGCCCC
GACGCGGCACCGACCGGTGC

Product: NADH:flavin oxidoreductase/NADH oxidase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MTALFSPFTLRGVTLPNRIVISPMCQYSAERGEATDWHMIHLGHLALSGAGLLCIEATAVEPDGRITHGDLGLWDDVTEA
ALKPVLAAIRKHSPIRVAMQLSHAGRKASSAAPWEGGQLVPVADGGWLPHGPSAVPHKDGETPPLALDAAGLNRIREAFA
ASARRAARLGIDAIEVHAAHGYLLHQFLSPLANRRTDEYGGSRENRMRFPLEIFEIVRAAFPEDRPVGVRVSATDWVEGG
WELDDTIAFAHELKRRGCDWIDVSSGGVSPLQKIPLSPGYQVPFAQAVKRSVGMPTIAVGLINEPAHANRLIEAGDADFV
AMARAMLYDPRWPWHAAAELGAQVTAPPQYWRSQPREHKALFGDVSFGQR

Sequences:

>Translated_370_residues
MTALFSPFTLRGVTLPNRIVISPMCQYSAERGEATDWHMIHLGHLALSGAGLLCIEATAVEPDGRITHGDLGLWDDVTEA
ALKPVLAAIRKHSPIRVAMQLSHAGRKASSAAPWEGGQLVPVADGGWLPHGPSAVPHKDGETPPLALDAAGLNRIREAFA
ASARRAARLGIDAIEVHAAHGYLLHQFLSPLANRRTDEYGGSRENRMRFPLEIFEIVRAAFPEDRPVGVRVSATDWVEGG
WELDDTIAFAHELKRRGCDWIDVSSGGVSPLQKIPLSPGYQVPFAQAVKRSVGMPTIAVGLINEPAHANRLIEAGDADFV
AMARAMLYDPRWPWHAAAELGAQVTAPPQYWRSQPREHKALFGDVSFGQR
>Mature_369_residues
TALFSPFTLRGVTLPNRIVISPMCQYSAERGEATDWHMIHLGHLALSGAGLLCIEATAVEPDGRITHGDLGLWDDVTEAA
LKPVLAAIRKHSPIRVAMQLSHAGRKASSAAPWEGGQLVPVADGGWLPHGPSAVPHKDGETPPLALDAAGLNRIREAFAA
SARRAARLGIDAIEVHAAHGYLLHQFLSPLANRRTDEYGGSRENRMRFPLEIFEIVRAAFPEDRPVGVRVSATDWVEGGW
ELDDTIAFAHELKRRGCDWIDVSSGGVSPLQKIPLSPGYQVPFAQAVKRSVGMPTIAVGLINEPAHANRLIEAGDADFVA
MARAMLYDPRWPWHAAAELGAQVTAPPQYWRSQPREHKALFGDVSFGQR

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789463, Length=332, Percent_Identity=26.8072289156627, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787939, Length=341, Percent_Identity=30.791788856305, Blast_Score=109, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI72001454, Length=192, Percent_Identity=32.8125, Blast_Score=107, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17559802, Length=178, Percent_Identity=33.1460674157303, Blast_Score=104, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17564188, Length=198, Percent_Identity=30.3030303030303, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17559804, Length=197, Percent_Identity=29.9492385786802, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17540738, Length=203, Percent_Identity=30.0492610837438, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17565138, Length=270, Percent_Identity=25.5555555555556, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17566914, Length=282, Percent_Identity=26.9503546099291, Blast_Score=89, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6321973, Length=265, Percent_Identity=28.3018867924528, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6325086, Length=234, Percent_Identity=27.3504273504274, Blast_Score=88, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 40208; Mature: 40077

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALFSPFTLRGVTLPNRIVISPMCQYSAERGEATDWHMIHLGHLALSGAGLLCIEATAV
CCCCCCCCEEECCCCCCEEEECHHHHHCCCCCCCCCEEEEEEHHHHHCCCCEEEEEEEEE
EPDGRITHGDLGLWDDVTEAALKPVLAAIRKHSPIRVAMQLSHAGRKASSAAPWEGGQLV
CCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHCCCCCCCCCCCCCCEEE
PVADGGWLPHGPSAVPHKDGETPPLALDAAGLNRIREAFAASARRAARLGIDAIEVHAAH
EECCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHH
GYLLHQFLSPLANRRTDEYGGSRENRMRFPLEIFEIVRAAFPEDRPVGVRVSATDWVEGG
HHHHHHHHHHHHHCCCHHCCCCCCCCEECCHHHHHHHHHHCCCCCCCEEEEECCHHCCCC
WELDDTIAFAHELKRRGCDWIDVSSGGVSPLQKIPLSPGYQVPFAQAVKRSVGMPTIAVG
CCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHCCCCCCCCCCHHHHHHHHCCCCEEEEE
LINEPAHANRLIEAGDADFVAMARAMLYDPRWPWHAAAELGAQVTAPPQYWRSQPREHKA
ECCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHHCCCCHHHH
LFGDVSFGQR
EECCCCCCCC
>Mature Secondary Structure 
TALFSPFTLRGVTLPNRIVISPMCQYSAERGEATDWHMIHLGHLALSGAGLLCIEATAV
CCCCCCCEEECCCCCCEEEECHHHHHCCCCCCCCCEEEEEEHHHHHCCCCEEEEEEEEE
EPDGRITHGDLGLWDDVTEAALKPVLAAIRKHSPIRVAMQLSHAGRKASSAAPWEGGQLV
CCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHCCCCCCCCCCCCCCEEE
PVADGGWLPHGPSAVPHKDGETPPLALDAAGLNRIREAFAASARRAARLGIDAIEVHAAH
EECCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHH
GYLLHQFLSPLANRRTDEYGGSRENRMRFPLEIFEIVRAAFPEDRPVGVRVSATDWVEGG
HHHHHHHHHHHHHCCCHHCCCCCCCCEECCHHHHHHHHHHCCCCCCCEEEEECCHHCCCC
WELDDTIAFAHELKRRGCDWIDVSSGGVSPLQKIPLSPGYQVPFAQAVKRSVGMPTIAVG
CCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHCCCCCCCCCCHHHHHHHHCCCCEEEEE
LINEPAHANRLIEAGDADFVAMARAMLYDPRWPWHAAAELGAQVTAPPQYWRSQPREHKA
ECCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHHCCCCHHHH
LFGDVSFGQR
EECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA