Click here to switch to the map view.

The map label for this gene is marR [H]

Identifier: 116688072

GI number: 116688072

Start: 49622

End: 50110

Strand: Reverse

Name: marR [H]

Synonym: Bcen2424_0048

Alternate gene names: 116688072

Gene position: 50110-49622 (Counterclockwise)

Preceding gene: 116688075

Following gene: 116688071

Centisome position: 1.44

GC content: 67.69

Gene sequence:

>489_bases
ATGACCGGCGGCCTCTACGATCCCGAGAACATCGCGCTGGAAACGAGCCTCGGCTATTACCTGTCGAAGGCGAAGCAGGC
GCTCGTCGAGCGGATGGATCGCGCGCTCGAGCCGTTCGACCTCACCGCGCAGCAGATCGGCGTGATCCTGCTGCTGTCGC
GCGGCTACGCGCGCACGCCGTTCGAACTGTCGCGCAAGATGTCGTACGACAGCGGCTCGATGACGCGCATGCTCGACCGG
CTCGAACGCAAGGGACTGATCGCACGGGCGCGCAGCGAGCAGGACCGCCGGATGATCGAGCTGACGCTGACCGAGCGCGG
CATCGAAGCCGCCCGCGCGCTGCCGTCGCTGGTCGCGACCGTGCTCAACGCGCAACTCGAAGGCTTCTCGGCCGACGAAC
TCGCGACGCTCACCGGCCTGCTGCAACGCTTCATCGCCAACGGGCCCGGTTCGACCGGCTGCCCGAAGCCCGACGAACCC
GATTGCTGA

Upstream 100 bases:

>100_bases
TCGTAACTGGTTGACTCAAATAATATTGACTAAGCAATCATTTTTCAAGATACTGGGCGCGTTTTAACCCGAAACGCACT
ATTGCTGCGCGCGCAATCGT

Downstream 100 bases:

>100_bases
CGCGTGCGGAGCCCCATGTCTAGGTTAAACACTCGCTTATTTCTCTGTCTGGGCAGAAGATGACAAGGCACCCGCTCCCC
TTTTCCTCTTTTTTATTCCA

Product: MarR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MTGGLYDPENIALETSLGYYLSKAKQALVERMDRALEPFDLTAQQIGVILLLSRGYARTPFELSRKMSYDSGSMTRMLDR
LERKGLIARARSEQDRRMIELTLTERGIEAARALPSLVATVLNAQLEGFSADELATLTGLLQRFIANGPGSTGCPKPDEP
DC

Sequences:

>Translated_162_residues
MTGGLYDPENIALETSLGYYLSKAKQALVERMDRALEPFDLTAQQIGVILLLSRGYARTPFELSRKMSYDSGSMTRMLDR
LERKGLIARARSEQDRRMIELTLTERGIEAARALPSLVATVLNAQLEGFSADELATLTGLLQRFIANGPGSTGCPKPDEP
DC
>Mature_161_residues
TGGLYDPENIALETSLGYYLSKAKQALVERMDRALEPFDLTAQQIGVILLLSRGYARTPFELSRKMSYDSGSMTRMLDRL
ERKGLIARARSEQDRRMIELTLTERGIEAARALPSLVATVLNAQLEGFSADELATLTGLLQRFIANGPGSTGCPKPDEPD
C

Specific function: Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes. Binds to the marO operator/promoter site [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081927, Length=130, Percent_Identity=33.8461538461538, Blast_Score=71, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR023187
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 17856; Mature: 17725

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS01117 HTH_MARR_1 ; PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGGLYDPENIALETSLGYYLSKAKQALVERMDRALEPFDLTAQQIGVILLLSRGYARTP
CCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHEECCCCCCCC
FELSRKMSYDSGSMTRMLDRLERKGLIARARSEQDRRMIELTLTERGIEAARALPSLVAT
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLNAQLEGFSADELATLTGLLQRFIANGPGSTGCPKPDEPDC
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TGGLYDPENIALETSLGYYLSKAKQALVERMDRALEPFDLTAQQIGVILLLSRGYARTP
CCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHEECCCCCCCC
FELSRKMSYDSGSMTRMLDRLERKGLIARARSEQDRRMIELTLTERGIEAARALPSLVAT
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLNAQLEGFSADELATLTGLLQRFIANGPGSTGCPKPDEPDC
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8383113; 9097039; 9278503; 8282690; 7768850; 10760140 [H]