Click here to switch to the map view.

The map label for this gene is cidA [H]

Identifier: 116688067

GI number: 116688067

Start: 45580

End: 46053

Strand: Reverse

Name: cidA [H]

Synonym: Bcen2424_0043

Alternate gene names: 116688067

Gene position: 46053-45580 (Counterclockwise)

Preceding gene: 116688069

Following gene: 116688066

Centisome position: 1.32

GC content: 74.26

Gene sequence:

>474_bases
ATGAACAAGCCGACCGCCACTGCCGCCGCCCGCCCCGCCGCTTCGGGCAGCCTCGCGCACACGGGCCGGATCGTGCTGCA
GGCCACCGCGCTCGGCGTGCTGTGGATGGCGGTCGACTGGGCCGTGCGCACGGTCGGGCTGCCGGTTCCGTCCGGCGTGA
TCGGCCTCGCGGTGCTCCTCGTGCTGCTGTTCTCGGGCCGCGTCGCGCCGGCGTGGGTGAAGGACGGCGCGAACTGGCTC
TTGTCCGACATGCTGCTGTTCTTCGTGCCGGCCGCCGTCGCGGCCGTGCAGTACGGCGGGCTGTTCCGCGAGGACGGCTG
GCGCATCGCGCTGGTGATGCTCGCCGGCACCGCGTTCGTGATGGTCGCGGTGGCCGTCGCGGTCGATCTCGCCGCGAAGC
TCGAACGCCGGCTCGCCGCGCAGCGCGTGTTCGCGGAGCGCCGCCGCGCGCGCCTGAGCGCCGTCGCTCACTGA

Upstream 100 bases:

>100_bases
CCGAATTGGAATGACAAGAATAGAGAGAAGTCATTTTATTTATGGTTAGGGGAAACCCTATACTTGCTCCATTGACAGAA
ACATCTGTATGGAGCCCGCC

Downstream 100 bases:

>100_bases
GCGGGAGCCTGCCATGCTCGCCGCGCTATCGAACCTGCCCGCCGACCGGGTGAATACCGCGATCTCCGTCGGCTGCTTCG
TGCTGACGATCGTGCTGTAT

Product: LrgA family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MNKPTATAAARPAASGSLAHTGRIVLQATALGVLWMAVDWAVRTVGLPVPSGVIGLAVLLVLLFSGRVAPAWVKDGANWL
LSDMLLFFVPAAVAAVQYGGLFREDGWRIALVMLAGTAFVMVAVAVAVDLAAKLERRLAAQRVFAERRRARLSAVAH

Sequences:

>Translated_157_residues
MNKPTATAAARPAASGSLAHTGRIVLQATALGVLWMAVDWAVRTVGLPVPSGVIGLAVLLVLLFSGRVAPAWVKDGANWL
LSDMLLFFVPAAVAAVQYGGLFREDGWRIALVMLAGTAFVMVAVAVAVDLAAKLERRLAAQRVFAERRRARLSAVAH
>Mature_157_residues
MNKPTATAAARPAASGSLAHTGRIVLQATALGVLWMAVDWAVRTVGLPVPSGVIGLAVLLVLLFSGRVAPAWVKDGANWL
LSDMLLFFVPAAVAAVQYGGLFREDGWRIALVMLAGTAFVMVAVAVAVDLAAKLERRLAAQRVFAERRRARLSAVAH

Specific function: Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. W

COG id: COG1380

COG function: function code R; Putative effector of murein hydrolase LrgA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidA/LrgA family. CidA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005538 [H]

Pfam domain/function: PF03788 LrgA [H]

EC number: NA

Molecular weight: Translated: 16555; Mature: 16555

Theoretical pI: Translated: 12.01; Mature: 12.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKPTATAAARPAASGSLAHTGRIVLQATALGVLWMAVDWAVRTVGLPVPSGVIGLAVLL
CCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
VLLFSGRVAPAWVKDGANWLLSDMLLFFVPAAVAAVQYGGLFREDGWRIALVMLAGTAFV
HHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCEEHHHHHHHHHHH
MVAVAVAVDLAAKLERRLAAQRVFAERRRARLSAVAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNKPTATAAARPAASGSLAHTGRIVLQATALGVLWMAVDWAVRTVGLPVPSGVIGLAVLL
CCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
VLLFSGRVAPAWVKDGANWLLSDMLLFFVPAAVAAVQYGGLFREDGWRIALVMLAGTAFV
HHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCEEHHHHHHHHHHH
MVAVAVAVDLAAKLERRLAAQRVFAERRRARLSAVAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA