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The map label for this gene is insF1 [C]

Identifier: 116626965

GI number: 116626965

Start: 9953359

End: 9954645

Strand: Direct

Name: insF1 [C]

Synonym: Acid_7942

Alternate gene names: 116626965

Gene position: 9953359-9954645 (Clockwise)

Preceding gene: 116626964

Following gene: 116626966

Centisome position: 99.88

GC content: 58.51

Gene sequence:

>1287_bases
ATGGCCAAGATGAAAAAGTGGCGTCGACACACTATAGAATTCAAGCGGCAGGCCGTCGAACGAATGAAGACCTGCGAAAA
CATTGAGGCTTTAGCTCGCGAACTCAAGATCCAGCGGAAGCTTCTTTACACCTGGCGGTATCAGCTCGAGGGCCGGCCCG
AACCGCGGCACGCCAACCTGGGAATTGCCGCGGAAGACCGCAAAGAGAAACGACTCCGGGAGGAGAACGCCAAGCTGAAA
TCGGCTCTGGCGGATAAAGTCCTGGAGATCGAGCTTTTTCAACATGCCTTGCTCAAATTAAAGGAGGCACGGCCCACAGC
CTGGCGCCTCAGCGTCTACGAAGTCATCCGTTCGATGACGCAAGAGCAAGGCAAGTTAAGCATCCAACGGATGTGCCAAC
TCGTCGGCGTCAGCCGGGCCGGATATTACCGGCACTGGGAGGTCGTAGCTCCGGACGAAGCGGAAATGGCGGCCAGGGAT
GCCATCCAGAAGGTGGTGCTCGCGCACCATCGACGGTACGGCTACCGGCGCGTCACCGCGCAACTGCATCGACAGGGAAA
CATCATCAATCACAAGCGGGTGCTGCGCATTTTGGGTGAGGACAACCTGCTGGCGATCCGCTACCGCAAGTACATTATGA
CCACCGATTCGCGGCACGACTACCCGGTCTACGTGAATCTGGCTGCGCGCATGAGATTGACCGGCATCAACCAGCTGTGG
ATCGCCGACATCACCTACATCCGGCTGCGCACGGAGTTTGTCTATCTGGCGATCGTGCTCGACCGATTCTCACGTAAGGC
AATCGGTTGGTCGCTGGATCGGGCGCTGGCTGCCCGAATCGCGGTGGCGGCCTTGGAGCAGGCCGTGGAGAGACGGCAGC
CGCCGCCGGGCGTGGTGGTGCACAACGATCAGGGTATCCAGTTTGTCTGCCACGAATTTCAAGAGGTGGTGAAAGCTCAC
GGGATGGTGCCCAGCCTGAGCCGCCCGGCGAATCCGTACGACAATGCCGCCTGTGAAAGTTTCATGAAGACGCTGAAGCA
GGAGGAAATCTACTGCCACCGGTACCAGGATTTCGATGAACTTTCCGCCCATGTGGAAGAGTTCATCGAAACCTACTACA
ACCGGCAACGGCTGCACTCGGCACTGGGCTATCGGACGCCGGAAGAATTTGAGCGGGATGGCATCTCAGCCCCGAATTCC
GGCACCCACAATGCGGCGACCATGCTGGTGTTTACTCCGAAGGAAGAAGAGGGTTCCGGCGGGCCAGATTCCATCTCTCC
GCGATGA

Upstream 100 bases:

>100_bases
TAATACTGATGTAACCAGTGTTTGTGTTTTTTTGCTTATGGAGTGAACCCCAAAAGTGAGACAGGAGGAATAGACGCACT
TTGCATCGAATGGAGGCAAA

Downstream 100 bases:

>100_bases
CTCAGGCAAAGAAATGGCACGAAAGGCAAAGTTCGCCCGCTACCGGGAACATCTCCGCACGACCGGGCCGGTCAGCCTGG
GGGGTTCTTCCATCGTCAAG

Product: integrase catalytic subunit

Products: NA

Alternate protein names: ISO-S3 31 kDa protein [H]

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MAKMKKWRRHTIEFKRQAVERMKTCENIEALARELKIQRKLLYTWRYQLEGRPEPRHANLGIAAEDRKEKRLREENAKLK
SALADKVLEIELFQHALLKLKEARPTAWRLSVYEVIRSMTQEQGKLSIQRMCQLVGVSRAGYYRHWEVVAPDEAEMAARD
AIQKVVLAHHRRYGYRRVTAQLHRQGNIINHKRVLRILGEDNLLAIRYRKYIMTTDSRHDYPVYVNLAARMRLTGINQLW
IADITYIRLRTEFVYLAIVLDRFSRKAIGWSLDRALAARIAVAALEQAVERRQPPPGVVVHNDQGIQFVCHEFQEVVKAH
GMVPSLSRPANPYDNAACESFMKTLKQEEIYCHRYQDFDELSAHVEEFIETYYNRQRLHSALGYRTPEEFERDGISAPNS
GTHNAATMLVFTPKEEEGSGGPDSISPR

Sequences:

>Translated_428_residues
MAKMKKWRRHTIEFKRQAVERMKTCENIEALARELKIQRKLLYTWRYQLEGRPEPRHANLGIAAEDRKEKRLREENAKLK
SALADKVLEIELFQHALLKLKEARPTAWRLSVYEVIRSMTQEQGKLSIQRMCQLVGVSRAGYYRHWEVVAPDEAEMAARD
AIQKVVLAHHRRYGYRRVTAQLHRQGNIINHKRVLRILGEDNLLAIRYRKYIMTTDSRHDYPVYVNLAARMRLTGINQLW
IADITYIRLRTEFVYLAIVLDRFSRKAIGWSLDRALAARIAVAALEQAVERRQPPPGVVVHNDQGIQFVCHEFQEVVKAH
GMVPSLSRPANPYDNAACESFMKTLKQEEIYCHRYQDFDELSAHVEEFIETYYNRQRLHSALGYRTPEEFERDGISAPNS
GTHNAATMLVFTPKEEEGSGGPDSISPR
>Mature_427_residues
AKMKKWRRHTIEFKRQAVERMKTCENIEALARELKIQRKLLYTWRYQLEGRPEPRHANLGIAAEDRKEKRLREENAKLKS
ALADKVLEIELFQHALLKLKEARPTAWRLSVYEVIRSMTQEQGKLSIQRMCQLVGVSRAGYYRHWEVVAPDEAEMAARDA
IQKVVLAHHRRYGYRRVTAQLHRQGNIINHKRVLRILGEDNLLAIRYRKYIMTTDSRHDYPVYVNLAARMRLTGINQLWI
ADITYIRLRTEFVYLAIVLDRFSRKAIGWSLDRALAARIAVAALEQAVERRQPPPGVVVHNDQGIQFVCHEFQEVVKAHG
MVPSLSRPANPYDNAACESFMKTLKQEEIYCHRYQDFDELSAHVEEFIETYYNRQRLHSALGYRTPEEFERDGISAPNSG
THNAATMLVFTPKEEEGSGGPDSISPR

Specific function: Involved in the transposition of the insertion sequence is3 [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=256, Percent_Identity=27.34375, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1788405, Length=283, Percent_Identity=35.3356890459364, Blast_Score=161, Evalue=1e-40,
Organism=Escherichia coli, GI1787263, Length=283, Percent_Identity=35.3356890459364, Blast_Score=161, Evalue=1e-40,
Organism=Escherichia coli, GI1786753, Length=283, Percent_Identity=35.3356890459364, Blast_Score=161, Evalue=1e-40,
Organism=Escherichia coli, GI1786570, Length=283, Percent_Identity=35.3356890459364, Blast_Score=161, Evalue=1e-40,
Organism=Escherichia coli, GI1786490, Length=283, Percent_Identity=35.3356890459364, Blast_Score=161, Evalue=1e-40,
Organism=Escherichia coli, GI1789981, Length=259, Percent_Identity=33.5907335907336, Blast_Score=138, Evalue=8e-34,
Organism=Escherichia coli, GI1790724, Length=231, Percent_Identity=29.4372294372294, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1789424, Length=231, Percent_Identity=29.4372294372294, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1789224, Length=231, Percent_Identity=29.4372294372294, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1788305, Length=231, Percent_Identity=29.4372294372294, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1787669, Length=231, Percent_Identity=29.4372294372294, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1786558, Length=231, Percent_Identity=29.4372294372294, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 49835; Mature: 49704

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKMKKWRRHTIEFKRQAVERMKTCENIEALARELKIQRKLLYTWRYQLEGRPEPRHANL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCC
GIAAEDRKEKRLREENAKLKSALADKVLEIELFQHALLKLKEARPTAWRLSVYEVIRSMT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
QEQGKLSIQRMCQLVGVSRAGYYRHWEVVAPDEAEMAARDAIQKVVLAHHRRYGYRRVTA
HHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHHH
QLHRQGNIINHKRVLRILGEDNLLAIRYRKYIMTTDSRHDYPVYVNLAARMRLTGINQLW
HHHHCCCCCHHHHHHHHHCCCCEEEEEEEHHEEECCCCCCCCEEEEEEHHHHHCCCCHHH
IADITYIRLRTEFVYLAIVLDRFSRKAIGWSLDRALAARIAVAALEQAVERRQPPPGVVV
HHHHHHEEHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
HNDQGIQFVCHEFQEVVKAHGMVPSLSRPANPYDNAACESFMKTLKQEEIYCHRYQDFDE
ECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHH
LSAHVEEFIETYYNRQRLHSALGYRTPEEFERDGISAPNSGTHNAATMLVFTPKEEEGSG
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCC
GPDSISPR
CCCCCCCC
>Mature Secondary Structure 
AKMKKWRRHTIEFKRQAVERMKTCENIEALARELKIQRKLLYTWRYQLEGRPEPRHANL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCC
GIAAEDRKEKRLREENAKLKSALADKVLEIELFQHALLKLKEARPTAWRLSVYEVIRSMT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
QEQGKLSIQRMCQLVGVSRAGYYRHWEVVAPDEAEMAARDAIQKVVLAHHRRYGYRRVTA
HHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHHH
QLHRQGNIINHKRVLRILGEDNLLAIRYRKYIMTTDSRHDYPVYVNLAARMRLTGINQLW
HHHHCCCCCHHHHHHHHHCCCCEEEEEEEHHEEECCCCCCCCEEEEEEHHHHHCCCCHHH
IADITYIRLRTEFVYLAIVLDRFSRKAIGWSLDRALAARIAVAALEQAVERRQPPPGVVV
HHHHHHEEHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
HNDQGIQFVCHEFQEVVKAHGMVPSLSRPANPYDNAACESFMKTLKQEEIYCHRYQDFDE
ECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHH
LSAHVEEFIETYYNRQRLHSALGYRTPEEFERDGISAPNSGTHNAATMLVFTPKEEEGSG
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCC
GPDSISPR
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2824781 [H]