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The map label for this gene is dnaC [H]

Identifier: 116626880

GI number: 116626880

Start: 9856429

End: 9857793

Strand: Direct

Name: dnaC [H]

Synonym: Acid_7856

Alternate gene names: 116626880

Gene position: 9856429-9857793 (Clockwise)

Preceding gene: 116626875

Following gene: 116626882

Centisome position: 98.9

GC content: 60.22

Gene sequence:

>1365_bases
ATGTCGGGTTCCAACGTCAGCGAAAAAGGACTTCCCACCAACGTAGATGCCGAGCGATTCGTGCTCGGGTCCATCCTGCT
CGAAGATAGCTTCTACATCCAGGCGGCTGGCACGCTGGAGATCAATGACTTCAGCCTGGAAAAGCATCGCCGCATCTTCA
AGCGCATGGGAGAGATCTACGAGCGCGGCGAAAAGATCGACCGCATCACCGTCGCCAACGAGTTGATGAAATTCAACGAA
CTGGAGAGCTGCGACGGCCTGAGCTATCTGGTTTCGCTGGACGACGGGCTACCCCAGATCCCGAACGTGGATGCCTACAT
CCGGCTGGTGAAGGATAAGGCGGTGCTGCGCAGCATCATTTTCGCCAGCCAGCACATGATCAACCGCTGCATGATGGCGG
AGGAAGCGCCGGACGAGATTCTGGCCGGCGCCGAAGAGACCCTGCTCAAACTCGGAGAGGCCCAGGTCAAAAGCGGGCTG
CTCAACCCCGACGAGATTCTGCAGAACTATGACGGCGGCATCAGCGCTTTCCTGGACCCCAGCAAACGAGTCAAAGGCGT
GAGCACCGGCTTCCTGAAGCTGGATGAATACACCGGCGGCATGCACGGCGGCGATCTCTTCATTCTGGCGGCCAGGCCGT
CGATGGGGAAAACCGCCTTCGCGCTCAATATCGCGCAGCACGTGGCGCTGCGCATGAAACAGACAGTGGCGGTCTTCTCG
CTCGAAATGTCCAAGGAGAGTCTGTTGACCCGCATGTTGTGCGCGTCGGCACGCGTGGATAGCCAGCGCTTCCGGACCGG
ATACCTTTCGCAGGACGAGCGCCGCAAGCTGAACCAATCGCTGCAGGACCTGGTGGAAGCGCCCCTGTATATCGACGACA
CCGCGGGACTCCACCTGATGGACATGCACGCCAAGCTCCGGCGGCTGAAATCAGAGCGCGGCAAGCTCGGCCTGGTCATC
GTGGATTACCTGCAGCTGATGAGTTCGCGCGGGCGCGTGGAAAACCGCAACCAGGAAGTCAGCGCCCTCTCCCGCGGATT
GAAACTGTTGGCGAAGGAATTGAATGTGCCGATGATGGTACTTTCCCAGTTGAGCCGCGCGGTGGAAACGCGCCAGGGCG
ACCACCGGCCGGTGCTCAGCGACCTTCGCGAGTCGGGATCGATCGAGCAGGACGCCGACGTGGTGGGCTTCATTTTTCGT
GAAGAGGTCTACAACAGGGATCGCGAAGATCTCAAGGGGCTGGCGGAACTGATCATCGCCAAGCAGCGCAATGGCCCGGT
GGGCACGGTCAACCTGGTCTTCCTGCATGCGCAGACCAAGTTCGAGAACCGCGCCGAAGACACTGGCGAGATGCCGGACG
AATAG

Upstream 100 bases:

>100_bases
GCGCATCAAAGCGGTTATACTTCCACCGCATTATTCGTCCCTCACAACCTCAAAAGCGTTGACCATGCGTCTCACGAGAG
CGTAGTCTAGGCATTGGCTC

Downstream 100 bases:

>100_bases
AAGGCTACCCGCGCTTCACGAAAATCTCTGCCTGCGTGAACGCAACCGCGCGGAGCTGGTCGCGCAGGGTGCTGTATCTC
ACCAGGTCGCGCGCGGCGCG

Product: primary replicative DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MSGSNVSEKGLPTNVDAERFVLGSILLEDSFYIQAAGTLEINDFSLEKHRRIFKRMGEIYERGEKIDRITVANELMKFNE
LESCDGLSYLVSLDDGLPQIPNVDAYIRLVKDKAVLRSIIFASQHMINRCMMAEEAPDEILAGAEETLLKLGEAQVKSGL
LNPDEILQNYDGGISAFLDPSKRVKGVSTGFLKLDEYTGGMHGGDLFILAARPSMGKTAFALNIAQHVALRMKQTVAVFS
LEMSKESLLTRMLCASARVDSQRFRTGYLSQDERRKLNQSLQDLVEAPLYIDDTAGLHLMDMHAKLRRLKSERGKLGLVI
VDYLQLMSSRGRVENRNQEVSALSRGLKLLAKELNVPMMVLSQLSRAVETRQGDHRPVLSDLRESGSIEQDADVVGFIFR
EEVYNRDREDLKGLAELIIAKQRNGPVGTVNLVFLHAQTKFENRAEDTGEMPDE

Sequences:

>Translated_454_residues
MSGSNVSEKGLPTNVDAERFVLGSILLEDSFYIQAAGTLEINDFSLEKHRRIFKRMGEIYERGEKIDRITVANELMKFNE
LESCDGLSYLVSLDDGLPQIPNVDAYIRLVKDKAVLRSIIFASQHMINRCMMAEEAPDEILAGAEETLLKLGEAQVKSGL
LNPDEILQNYDGGISAFLDPSKRVKGVSTGFLKLDEYTGGMHGGDLFILAARPSMGKTAFALNIAQHVALRMKQTVAVFS
LEMSKESLLTRMLCASARVDSQRFRTGYLSQDERRKLNQSLQDLVEAPLYIDDTAGLHLMDMHAKLRRLKSERGKLGLVI
VDYLQLMSSRGRVENRNQEVSALSRGLKLLAKELNVPMMVLSQLSRAVETRQGDHRPVLSDLRESGSIEQDADVVGFIFR
EEVYNRDREDLKGLAELIIAKQRNGPVGTVNLVFLHAQTKFENRAEDTGEMPDE
>Mature_453_residues
SGSNVSEKGLPTNVDAERFVLGSILLEDSFYIQAAGTLEINDFSLEKHRRIFKRMGEIYERGEKIDRITVANELMKFNEL
ESCDGLSYLVSLDDGLPQIPNVDAYIRLVKDKAVLRSIIFASQHMINRCMMAEEAPDEILAGAEETLLKLGEAQVKSGLL
NPDEILQNYDGGISAFLDPSKRVKGVSTGFLKLDEYTGGMHGGDLFILAARPSMGKTAFALNIAQHVALRMKQTVAVFSL
EMSKESLLTRMLCASARVDSQRFRTGYLSQDERRKLNQSLQDLVEAPLYIDDTAGLHLMDMHAKLRRLKSERGKLGLVIV
DYLQLMSSRGRVENRNQEVSALSRGLKLLAKELNVPMMVLSQLSRAVETRQGDHRPVLSDLRESGSIEQDADVVGFIFRE
EVYNRDREDLKGLAELIIAKQRNGPVGTVNLVFLHAQTKFENRAEDTGEMPDE

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=440, Percent_Identity=40, Blast_Score=323, Evalue=2e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 50785; Mature: 50654

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGSNVSEKGLPTNVDAERFVLGSILLEDSFYIQAAGTLEINDFSLEKHRRIFKRMGEIY
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCEEEECCCCHHHHHHHHHHHHHHH
ERGEKIDRITVANELMKFNELESCDGLSYLVSLDDGLPQIPNVDAYIRLVKDKAVLRSII
HCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHH
FASQHMINRCMMAEEAPDEILAGAEETLLKLGEAQVKSGLLNPDEILQNYDGGISAFLDP
HHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEECCCC
SKRVKGVSTGFLKLDEYTGGMHGGDLFILAARPSMGKTAFALNIAQHVALRMKQTVAVFS
HHHHCCCCCCCEEEECCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LEMSKESLLTRMLCASARVDSQRFRTGYLSQDERRKLNQSLQDLVEAPLYIDDTAGLHLM
HHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCEEHH
DMHAKLRRLKSERGKLGLVIVDYLQLMSSRGRVENRNQEVSALSRGLKLLAKELNVPMMV
HHHHHHHHHHHHCCCEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHH
LSQLSRAVETRQGDHRPVLSDLRESGSIEQDADVVGFIFREEVYNRDREDLKGLAELIIA
HHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
KQRNGPVGTVNLVFLHAQTKFENRAEDTGEMPDE
HCCCCCCEEEEEEEEEECHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SGSNVSEKGLPTNVDAERFVLGSILLEDSFYIQAAGTLEINDFSLEKHRRIFKRMGEIY
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCEEEECCCCHHHHHHHHHHHHHHH
ERGEKIDRITVANELMKFNELESCDGLSYLVSLDDGLPQIPNVDAYIRLVKDKAVLRSII
HCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHH
FASQHMINRCMMAEEAPDEILAGAEETLLKLGEAQVKSGLLNPDEILQNYDGGISAFLDP
HHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEECCCC
SKRVKGVSTGFLKLDEYTGGMHGGDLFILAARPSMGKTAFALNIAQHVALRMKQTVAVFS
HHHHCCCCCCCEEEECCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LEMSKESLLTRMLCASARVDSQRFRTGYLSQDERRKLNQSLQDLVEAPLYIDDTAGLHLM
HHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCEEHH
DMHAKLRRLKSERGKLGLVIVDYLQLMSSRGRVENRNQEVSALSRGLKLLAKELNVPMMV
HHHHHHHHHHHHCCCEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHH
LSQLSRAVETRQGDHRPVLSDLRESGSIEQDADVVGFIFREEVYNRDREDLKGLAELIIA
HHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
KQRNGPVGTVNLVFLHAQTKFENRAEDTGEMPDE
HCCCCCCEEEEEEEEEECHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]