Click here to switch to the map view.

The map label for this gene is yggV [C]

Identifier: 116626751

GI number: 116626751

Start: 9699206

End: 9699796

Strand: Direct

Name: yggV [C]

Synonym: Acid_7724

Alternate gene names: 116626751

Gene position: 9699206-9699796 (Clockwise)

Preceding gene: 116626750

Following gene: 116626754

Centisome position: 97.33

GC content: 62.1

Gene sequence:

>591_bases
TTGACGACGCTGTATTGCGCTACTGGGAACGCCGGCAAGCTGCGCGAATTTCGGATGGCGGCCGATCACGCACCATTCGA
TATCGAGCTGCTTCCGAATTACAAACAGCTTCCCGAAGCCGTGGAAGATGGCGCCACGTTCGAGGAGAACGCCATGAAGA
AGGCGATCCACTACAGTCCGCACGCGAGCGGCCTGTTATTCGCGGACGATTCAGGCCTTGAAGTCGAGGCGCTAGGCGGT
GCGCCGGGGGTGTATTCCGCGCGATACTCGGGCCCTGGCGCCACCGATGAACTGAACAACCGCCTCCTATTGGAGCGCAT
GCGCGGCGTGGAGAACCGGAGCGCGCGGTTTGTATGCGCGATCGCGCTCGCCGATCGGGACCGGGTGCTCGGCGCATGGA
GAGGTTTTGTCGAGGGCGTAATTCTGACCGAGGCCCGCGGCAGCGGCGGATTCGGTTACGATCCGCTGTTTTACTGTCCG
GCGTTCGCATGCACTTTTGGCGAAGCCACGGCCGAGCAGAAACTCTCGCTGAGCCACCGCGGGCAGGCCTTTCGTGCGAT
GACGCGAGACTACATCGGTGGCAAGTTGTAG

Upstream 100 bases:

>100_bases
AGCATAGCGCGTTCGACGATGCGCAGATGGCCGAGCTGACCGAGCTCGCGCGCACGGGAATCGCGCAACTGGTCCGCATG
CAGAAGGAGATCATCGAAGG

Downstream 100 bases:

>100_bases
ACTGCCGCTAAGCCGTTGAGGTCGCTTTTCAGAAGATCCCAGTCGCGCTGCAACTTCTCGGTGTATCGAAATTCCAGCAT
GACGCGATTGAGATCACTCG

Product: RdgB/HAM1 family non-canonical purine NTP pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MTTLYCATGNAGKLREFRMAADHAPFDIELLPNYKQLPEAVEDGATFEENAMKKAIHYSPHASGLLFADDSGLEVEALGG
APGVYSARYSGPGATDELNNRLLLERMRGVENRSARFVCAIALADRDRVLGAWRGFVEGVILTEARGSGGFGYDPLFYCP
AFACTFGEATAEQKLSLSHRGQAFRAMTRDYIGGKL

Sequences:

>Translated_196_residues
MTTLYCATGNAGKLREFRMAADHAPFDIELLPNYKQLPEAVEDGATFEENAMKKAIHYSPHASGLLFADDSGLEVEALGG
APGVYSARYSGPGATDELNNRLLLERMRGVENRSARFVCAIALADRDRVLGAWRGFVEGVILTEARGSGGFGYDPLFYCP
AFACTFGEATAEQKLSLSHRGQAFRAMTRDYIGGKL
>Mature_195_residues
TTLYCATGNAGKLREFRMAADHAPFDIELLPNYKQLPEAVEDGATFEENAMKKAIHYSPHASGLLFADDSGLEVEALGGA
PGVYSARYSGPGATDELNNRLLLERMRGVENRSARFVCAIALADRDRVLGAWRGFVEGVILTEARGSGGFGYDPLFYCPA
FACTFGEATAEQKLSLSHRGQAFRAMTRDYIGGKL

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Escherichia coli, GI1789324, Length=192, Percent_Identity=43.2291666666667, Blast_Score=135, Evalue=3e-33,
Organism=Drosophila melanogaster, GI19920712, Length=186, Percent_Identity=30.1075268817204, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 21281; Mature: 21150

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLYCATGNAGKLREFRMAADHAPFDIELLPNYKQLPEAVEDGATFEENAMKKAIHYSP
CCEEEEECCCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHCCCC
HASGLLFADDSGLEVEALGGAPGVYSARYSGPGATDELNNRLLLERMRGVENRSARFVCA
CCCEEEEECCCCCEEEECCCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEE
IALADRDRVLGAWRGFVEGVILTEARGSGGFGYDPLFYCPAFACTFGEATAEQKLSLSHR
EEECCCHHHHHHHHHHHCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHC
GQAFRAMTRDYIGGKL
CHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TTLYCATGNAGKLREFRMAADHAPFDIELLPNYKQLPEAVEDGATFEENAMKKAIHYSP
CEEEEECCCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHCCCC
HASGLLFADDSGLEVEALGGAPGVYSARYSGPGATDELNNRLLLERMRGVENRSARFVCA
CCCEEEEECCCCCEEEECCCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEE
IALADRDRVLGAWRGFVEGVILTEARGSGGFGYDPLFYCPAFACTFGEATAEQKLSLSHR
EEECCCHHHHHHHHHHHCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHC
GQAFRAMTRDYIGGKL
CHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA