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The map label for this gene is mreB [H]

Identifier: 116626636

GI number: 116626636

Start: 9533421

End: 9534440

Strand: Direct

Name: mreB [H]

Synonym: Acid_7601

Alternate gene names: 116626636

Gene position: 9533421-9534440 (Clockwise)

Preceding gene: 116626634

Following gene: 116626638

Centisome position: 95.66

GC content: 60.88

Gene sequence:

>1020_bases
ATGACCACAGCATCACTTCTCGGCCTGTTTTCTTCCGACCTGGCAATCGACCTTGGAACCGCCAACACCCTCGTGTTCGA
GCGAAACAAGGGCGTTGTAGTGAACGAACCCTCGATCGTGGCTATGCGTAAAGATTCCGGCGGTGTGGAAGCCGTGGGCG
CCGAGGCTCGAGAGATGCTCGGCCGCACGCCCGAGCAGATCACCGCGGTTAAGCCAATGAAGAATGGTGTAATCGCGGAC
TTCAAAGCCACCTCGCACATGCTGAATCATTTCATCAGCAAAGCCCGCCGATACAGCCGGATGGTGCACCCGCGGATTGT
GATCGGCGTTCCCAGTGAAATCACTCCGGTAGAACGCCGCGCTGTAAAGGACGCATGCGCTAAGGCCCGGGAGGTCTACC
TGGTGCAGCAGCCCGTGATGGCGGCAGTCGGCGCCGGGCTGCCGATTGGGGAGGCGGTGGGCAACCTTATCGTGGACATA
GGTGGCGGAACCACCGACGTCGCTGTGATCTCGCTCGCGGGCATCGTCTACGCGCACTCGGTGCGGGTCGCCGGCAACGC
AATGGATGAGGTAATCATCGACCACGTCAAGCGGAAGCACAATCTGCTGATTGGAGAGCGCACCGCGGAAGCAATCAAAA
TGCAAATTGGTTCGGCGTTTCCGCTGGACAACGAAATGCGGATGGAAGTGCGTGGCCGCGATTTGGCGCGCGGCCTTCCA
GCCGCGGTGACGGTCACTGACTCCGAAATCCGCAATGCGCTGTCCACCTGCGTAGCAACCATCGTGAACGCGATCAGAAT
CGCACTGGAACACACACCCCCCGAGCTGAGCGCCGATATCTCCGATCGCGGCGTCGTCTTGACCGGTGGCGGTGCGCTGT
TGAAGAAGCTCGACGTGCGCATCGGCAGCGAAACCGGACTGCCGGTCCTGATCGCCGACGACCCCCTGCTCTCAGTGGTG
GTCGGAGCGGGCACGATGCTCGATGACTTCGGCCTCTTGCGCCGTGTGTGCATGAACTAA

Upstream 100 bases:

>100_bases
CGTTGACGGGCGGTGCTAACCGTTAGTTAATACATCTGTCCTAACCCCTGCCAACCTTGCAGCCGTTCTCTGGCACTCTG
ATACTAATGGGCACTGAGTT

Downstream 100 bases:

>100_bases
CCGAATCGTGTCTGGTACCTCCCAGGACTAAGTTTGGCGCTTCCGAATAAACCGAAGAGATTCAATCGGATTTCGGGTGG
GAAAAACACCCGAGTACATC

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MTTASLLGLFSSDLAIDLGTANTLVFERNKGVVVNEPSIVAMRKDSGGVEAVGAEAREMLGRTPEQITAVKPMKNGVIAD
FKATSHMLNHFISKARRYSRMVHPRIVIGVPSEITPVERRAVKDACAKAREVYLVQQPVMAAVGAGLPIGEAVGNLIVDI
GGGTTDVAVISLAGIVYAHSVRVAGNAMDEVIIDHVKRKHNLLIGERTAEAIKMQIGSAFPLDNEMRMEVRGRDLARGLP
AAVTVTDSEIRNALSTCVATIVNAIRIALEHTPPELSADISDRGVVLTGGGALLKKLDVRIGSETGLPVLIADDPLLSVV
VGAGTMLDDFGLLRRVCMN

Sequences:

>Translated_339_residues
MTTASLLGLFSSDLAIDLGTANTLVFERNKGVVVNEPSIVAMRKDSGGVEAVGAEAREMLGRTPEQITAVKPMKNGVIAD
FKATSHMLNHFISKARRYSRMVHPRIVIGVPSEITPVERRAVKDACAKAREVYLVQQPVMAAVGAGLPIGEAVGNLIVDI
GGGTTDVAVISLAGIVYAHSVRVAGNAMDEVIIDHVKRKHNLLIGERTAEAIKMQIGSAFPLDNEMRMEVRGRDLARGLP
AAVTVTDSEIRNALSTCVATIVNAIRIALEHTPPELSADISDRGVVLTGGGALLKKLDVRIGSETGLPVLIADDPLLSVV
VGAGTMLDDFGLLRRVCMN
>Mature_338_residues
TTASLLGLFSSDLAIDLGTANTLVFERNKGVVVNEPSIVAMRKDSGGVEAVGAEAREMLGRTPEQITAVKPMKNGVIADF
KATSHMLNHFISKARRYSRMVHPRIVIGVPSEITPVERRAVKDACAKAREVYLVQQPVMAAVGAGLPIGEAVGNLIVDIG
GGTTDVAVISLAGIVYAHSVRVAGNAMDEVIIDHVKRKHNLLIGERTAEAIKMQIGSAFPLDNEMRMEVRGRDLARGLPA
AVTVTDSEIRNALSTCVATIVNAIRIALEHTPPELSADISDRGVVLTGGGALLKKLDVRIGSETGLPVLIADDPLLSVVV
GAGTMLDDFGLLRRVCMN

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=328, Percent_Identity=53.9634146341463, Blast_Score=350, Evalue=1e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 35922; Mature: 35791

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTASLLGLFSSDLAIDLGTANTLVFERNKGVVVNEPSIVAMRKDSGGVEAVGAEAREML
CCHHHHHHHHHCCCEEEECCCEEEEEECCCCEEEECCCEEEEECCCCCCCHHCHHHHHHH
GRTPEQITAVKPMKNGVIADFKATSHMLNHFISKARRYSRMVHPRIVIGVPSEITPVERR
CCCHHHHEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHH
AVKDACAKAREVYLVQQPVMAAVGAGLPIGEAVGNLIVDIGGGTTDVAVISLAGIVYAHS
HHHHHHHHHHHEEEEHHHHHHHHCCCCCHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHH
VRVAGNAMDEVIIDHVKRKHNLLIGERTAEAIKMQIGSAFPLDNEMRMEVRGRDLARGLP
EEECCCHHHHHHHHHHHHHHCEEEEHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHCCCC
AAVTVTDSEIRNALSTCVATIVNAIRIALEHTPPELSADISDRGVVLTGGGALLKKLDVR
EEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCHHHHHHHHHE
IGSETGLPVLIADDPLLSVVVGAGTMLDDFGLLRRVCMN
ECCCCCCEEEEECCCHHHHHHCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTASLLGLFSSDLAIDLGTANTLVFERNKGVVVNEPSIVAMRKDSGGVEAVGAEAREML
CHHHHHHHHHCCCEEEECCCEEEEEECCCCEEEECCCEEEEECCCCCCCHHCHHHHHHH
GRTPEQITAVKPMKNGVIADFKATSHMLNHFISKARRYSRMVHPRIVIGVPSEITPVERR
CCCHHHHEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHH
AVKDACAKAREVYLVQQPVMAAVGAGLPIGEAVGNLIVDIGGGTTDVAVISLAGIVYAHS
HHHHHHHHHHHEEEEHHHHHHHHCCCCCHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHH
VRVAGNAMDEVIIDHVKRKHNLLIGERTAEAIKMQIGSAFPLDNEMRMEVRGRDLARGLP
EEECCCHHHHHHHHHHHHHHCEEEEHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHCCCC
AAVTVTDSEIRNALSTCVATIVNAIRIALEHTPPELSADISDRGVVLTGGGALLKKLDVR
EEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCHHHHHHHHHE
IGSETGLPVLIADDPLLSVVVGAGTMLDDFGLLRRVCMN
ECCCCCCEEEEECCCHHHHHHCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]