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The map label for this gene is ctaD [H]

Identifier: 116626618

GI number: 116626618

Start: 9506580

End: 9508256

Strand: Direct

Name: ctaD [H]

Synonym: Acid_7581

Alternate gene names: 116626618

Gene position: 9506580-9508256 (Clockwise)

Preceding gene: 116626617

Following gene: 116626619

Centisome position: 95.39

GC content: 58.32

Gene sequence:

>1677_bases
ATGTCGGCCGTGATTGAGGCGGCATCGTCCACCCGGCCCGCGCCGCCAGCGCTGGTAAACCGGCTTCACGGGTGGATCAC
CACTGTCGATCACAAGCGTTTGGGCATCATGTACATTCTCTATGCCCTGGTATTTCTTGTGATCGGCGGGATCGAAGCGG
CGATTATGCGGACTCAGCTTATCGTGCCGCACAACCAGTTTGTCTCGCCGCAGGTCTTCAACCGGATGTTCACCATGCAT
GGCACGACGATGATCTTCTTCGTGGCCATGCCGCTCATTTTCGGCTTCGCCAACTACCTTCTCCCGCTGATGCTCGGGGC
GCGAGACATGGCGTTCCCCCGAATAAATGCTTTCAGCTTTTGGATGACTGCGTTTGGAGGCTGCCTCCTCTATCTCAGCC
TGGTGGGGGCATACGGCCTGTACGGTGCGGGAAACGCCCCCGACGTGGGATGGTTCGCCTACGCGCCGTTGACCTCTCAG
ACTTTTTCACGCGGGCACAGTACAGACTTCTGGATTCTGGCGGTCTTCATCTCCGGCATAGGCAGCATCGGCGGGGCCAT
CAACATTGTCTCCACGATTCTGTGCCTGCGGTGTCCGGGCATGACGCTCGCGAAAATGCCGTTGCTGGCGTGGATGTATC
TCGTGATGTCCGCCCTGGTCTTGATCGCGATCGGCCCGCTCACGGCTGCGCAGATCATGCTCCTGCTCGATCGCTACCTG
GGCGCGCACTTCTTCGACACTCAGGCCGGGGGCTCCGCCGTACTCTGGATGCACTTCTTCTGGATCTTCGGCCACCCGGA
GGTCTACATTCTGGTGATTCCAGCCTTCGCCTTCGTCTCCGAAATCGTCCCGGTGTTTTCGCGAAAGGCGATTTTCGGCT
ATCCCATCATGGTGGCCGCCACGCTCGCGATCGGTTTCGTCAGCGTGAGCGTGTGGGCACATCACATGTTCACCGTGGGG
CTGAGTTCCAATGCGAGCACGTTCTTCGTGCTATCGACAATGGCCATCGCTGTCCCGACCGGAATCAAAATCTTTAACTG
GCTGGCAACCATGTGGGGCGGGAAGCTTCACTTCCAGACGCCGATGCTGTTCTGCATCGGTTTTCTTTTCCAGTTCCTGG
TCGCCGGACTTACTGGAATCATGCTGAGCGCAGCGCCCTTTGACTGGCAACTCGGAAACTCTTACTTCGTGGTGGCGCAT
TTCCACTATGTCATCGTGGGCGGCATATTGTTCGCGCTTTTCGGCGCCTTCTATTACTGGTTTCCAAAGATGTCCGGGAA
GATGTATAGCGAAATGCTCGGCAGGCTGCACTTCGTACTATTCGTCATCGGCTTTCACCTCACGTTCGATAGTCTTCACA
TCCCCGGATTACTCGGCATGCCCCGCAGAATCTACACCTACGAACCCGGTAGAGGGTGGGACATCTGGAACGTCCTGGCG
ACTATTGGGGTGGTCTTTCAGGCTGCCGGCGTATTGGTCTTCGTCGCCAACCTGACGGCGTCTTACCTCAAGGGCAAGAG
TGCGGGAAACGATCCCTGGGACGCCTGGACGCTCGAGTGGTCCACGTCCTCGCCGCCACCCGCCTATAACTTCGCGCTGA
TTCCCTCGGTCAGAAGCCGCCGTCCGCTCTGGGATCTCAAGCACCCGGAGGATCCGGACTGGCGGTATGAGCAGTGA

Upstream 100 bases:

>100_bases
CGATGAAGCCCGGGTGCAGAATGCCGGCGATGAACTTGGGGGAGCGGGAGATAAGCGCCGTAGCCGCATACCTGGAGACA
CTTCGGTGAACGAACGTCCG

Downstream 100 bases:

>100_bases
GGATAGGGCAATGAGCGCCACTCCAATGACCATCCCCGGCACGGAACCGCCATGGGAACTTCCCTCGCGAGGGCGGGTGG
GAATGCTCTCGCTCATCGCA

Product: cytochrome-c oxidase

Products: NA

Alternate protein names: Caa-3605 subunit 1; Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I; Oxidase aa(3) subunit 1 [H]

Number of amino acids: Translated: 558; Mature: 557

Protein sequence:

>558_residues
MSAVIEAASSTRPAPPALVNRLHGWITTVDHKRLGIMYILYALVFLVIGGIEAAIMRTQLIVPHNQFVSPQVFNRMFTMH
GTTMIFFVAMPLIFGFANYLLPLMLGARDMAFPRINAFSFWMTAFGGCLLYLSLVGAYGLYGAGNAPDVGWFAYAPLTSQ
TFSRGHSTDFWILAVFISGIGSIGGAINIVSTILCLRCPGMTLAKMPLLAWMYLVMSALVLIAIGPLTAAQIMLLLDRYL
GAHFFDTQAGGSAVLWMHFFWIFGHPEVYILVIPAFAFVSEIVPVFSRKAIFGYPIMVAATLAIGFVSVSVWAHHMFTVG
LSSNASTFFVLSTMAIAVPTGIKIFNWLATMWGGKLHFQTPMLFCIGFLFQFLVAGLTGIMLSAAPFDWQLGNSYFVVAH
FHYVIVGGILFALFGAFYYWFPKMSGKMYSEMLGRLHFVLFVIGFHLTFDSLHIPGLLGMPRRIYTYEPGRGWDIWNVLA
TIGVVFQAAGVLVFVANLTASYLKGKSAGNDPWDAWTLEWSTSSPPPAYNFALIPSVRSRRPLWDLKHPEDPDWRYEQ

Sequences:

>Translated_558_residues
MSAVIEAASSTRPAPPALVNRLHGWITTVDHKRLGIMYILYALVFLVIGGIEAAIMRTQLIVPHNQFVSPQVFNRMFTMH
GTTMIFFVAMPLIFGFANYLLPLMLGARDMAFPRINAFSFWMTAFGGCLLYLSLVGAYGLYGAGNAPDVGWFAYAPLTSQ
TFSRGHSTDFWILAVFISGIGSIGGAINIVSTILCLRCPGMTLAKMPLLAWMYLVMSALVLIAIGPLTAAQIMLLLDRYL
GAHFFDTQAGGSAVLWMHFFWIFGHPEVYILVIPAFAFVSEIVPVFSRKAIFGYPIMVAATLAIGFVSVSVWAHHMFTVG
LSSNASTFFVLSTMAIAVPTGIKIFNWLATMWGGKLHFQTPMLFCIGFLFQFLVAGLTGIMLSAAPFDWQLGNSYFVVAH
FHYVIVGGILFALFGAFYYWFPKMSGKMYSEMLGRLHFVLFVIGFHLTFDSLHIPGLLGMPRRIYTYEPGRGWDIWNVLA
TIGVVFQAAGVLVFVANLTASYLKGKSAGNDPWDAWTLEWSTSSPPPAYNFALIPSVRSRRPLWDLKHPEDPDWRYEQ
>Mature_557_residues
SAVIEAASSTRPAPPALVNRLHGWITTVDHKRLGIMYILYALVFLVIGGIEAAIMRTQLIVPHNQFVSPQVFNRMFTMHG
TTMIFFVAMPLIFGFANYLLPLMLGARDMAFPRINAFSFWMTAFGGCLLYLSLVGAYGLYGAGNAPDVGWFAYAPLTSQT
FSRGHSTDFWILAVFISGIGSIGGAINIVSTILCLRCPGMTLAKMPLLAWMYLVMSALVLIAIGPLTAAQIMLLLDRYLG
AHFFDTQAGGSAVLWMHFFWIFGHPEVYILVIPAFAFVSEIVPVFSRKAIFGYPIMVAATLAIGFVSVSVWAHHMFTVGL
SSNASTFFVLSTMAIAVPTGIKIFNWLATMWGGKLHFQTPMLFCIGFLFQFLVAGLTGIMLSAAPFDWQLGNSYFVVAHF
HYVIVGGILFALFGAFYYWFPKMSGKMYSEMLGRLHFVLFVIGFHLTFDSLHIPGLLGMPRRIYTYEPGRGWDIWNVLAT
IGVVFQAAGVLVFVANLTASYLKGKSAGNDPWDAWTLEWSTSSPPPAYNFALIPSVRSRRPLWDLKHPEDPDWRYEQ

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=511, Percent_Identity=39.9217221135029, Blast_Score=350, Evalue=2e-96,
Organism=Escherichia coli, GI1786634, Length=544, Percent_Identity=42.8308823529412, Blast_Score=433, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6226519, Length=541, Percent_Identity=38.8170055452865, Blast_Score=356, Evalue=5e-99,
Organism=Saccharomyces cerevisiae, GI6226524, Length=331, Percent_Identity=42.2960725075529, Blast_Score=248, Evalue=2e-66,
Organism=Saccharomyces cerevisiae, GI6226523, Length=255, Percent_Identity=36.8627450980392, Blast_Score=145, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 61975; Mature: 61844

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVIEAASSTRPAPPALVNRLHGWITTVDHKRLGIMYILYALVFLVIGGIEAAIMRTQL
CCCHHHHHCCCCCCCHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHE
IVPHNQFVSPQVFNRMFTMHGTTMIFFVAMPLIFGFANYLLPLMLGARDMAFPRINAFSF
ECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHH
WMTAFGGCLLYLSLVGAYGLYGAGNAPDVGWFAYAPLTSQTFSRGHSTDFWILAVFISGI
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHHHHCCCCCCHHHHHHHHHHH
GSIGGAINIVSTILCLRCPGMTLAKMPLLAWMYLVMSALVLIAIGPLTAAQIMLLLDRYL
HHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
GAHFFDTQAGGSAVLWMHFFWIFGHPEVYILVIPAFAFVSEIVPVFSRKAIFGYPIMVAA
CCEEEECCCCCCEEHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHCCHHHCCHHHHHH
TLAIGFVSVSVWAHHMFTVGLSSNASTFFVLSTMAIAVPTGIKIFNWLATMWGGKLHFQT
HHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEECC
PMLFCIGFLFQFLVAGLTGIMLSAAPFDWQLGNSYFVVAHFHYVIVGGILFALFGAFYYW
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHH
FPKMSGKMYSEMLGRLHFVLFVIGFHLTFDSLHIPGLLGMPRRIYTYEPGRGWDIWNVLA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHH
TIGVVFQAAGVLVFVANLTASYLKGKSAGNDPWDAWTLEWSTSSPPPAYNFALIPSVRSR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCEEECCCCCCC
RPLWDLKHPEDPDWRYEQ
CCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SAVIEAASSTRPAPPALVNRLHGWITTVDHKRLGIMYILYALVFLVIGGIEAAIMRTQL
CCHHHHHCCCCCCCHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHE
IVPHNQFVSPQVFNRMFTMHGTTMIFFVAMPLIFGFANYLLPLMLGARDMAFPRINAFSF
ECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHH
WMTAFGGCLLYLSLVGAYGLYGAGNAPDVGWFAYAPLTSQTFSRGHSTDFWILAVFISGI
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHHHHCCCCCCHHHHHHHHHHH
GSIGGAINIVSTILCLRCPGMTLAKMPLLAWMYLVMSALVLIAIGPLTAAQIMLLLDRYL
HHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
GAHFFDTQAGGSAVLWMHFFWIFGHPEVYILVIPAFAFVSEIVPVFSRKAIFGYPIMVAA
CCEEEECCCCCCEEHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHCCHHHCCHHHHHH
TLAIGFVSVSVWAHHMFTVGLSSNASTFFVLSTMAIAVPTGIKIFNWLATMWGGKLHFQT
HHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEECC
PMLFCIGFLFQFLVAGLTGIMLSAAPFDWQLGNSYFVVAHFHYVIVGGILFALFGAFYYW
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHH
FPKMSGKMYSEMLGRLHFVLFVIGFHLTFDSLHIPGLLGMPRRIYTYEPGRGWDIWNVLA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHH
TIGVVFQAAGVLVFVANLTASYLKGKSAGNDPWDAWTLEWSTSSPPPAYNFALIPSVRSR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCEEECCCCCCC
RPLWDLKHPEDPDWRYEQ
CCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1847686; 9384377 [H]